Spatiotemporal Rescue of Memory Dysfunction in Drosophila

Science

Volumn 302, Issue 5651, 2003, Pages 1765-1768

  McGuire, Sean E ^a   Le, Phuong T ^a   Osborn, Alexander J ^a   Matsumoto, Kunihiro ^b   Davis, Ronald L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; ENZYMES;

MEMORY DEFECTS;

GENES;

GREEN FLUORESCENT PROTEIN; MESSENGER RNA;

GENE EXPRESSION; MEMORY; SPATIOTEMPORAL ANALYSIS;

ARTICLE; CENTRAL NERVOUS SYSTEM; DROSOPHILA; FLY; GENE EXPRESSION; LEARNING; MEMORY; MEMORY DISORDER; NONHUMAN; OLFACTORY NERVOUS SYSTEM; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENYLATE CYCLASE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CLONING, MOLECULAR; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION; GENOTYPE; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MEMORY; MUSHROOM BODIES; NEURONAL PLASTICITY; PHENOTYPE; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; TEMPERATURE; TRANSCRIPTION FACTORS; TRANSGENES;

BASIDIOMYCOTA; BRASSICA NAPUS VAR. NAPOBRASSICA; INSECTA;

EID: 0345168202     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1089035     Document Type: Article

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23. We would like to thank T. Lee for providing the pCaSpeR4 vector that contained the tubulin 1α promoter; S. Elledge for kindly providing yeast strains used in the study; L. Zong for technical assistance with embryo injections; C. Wilson for preparation of the brain cryosections; and G. Chamness and L. Luo for critically reading drafts of the manuscript. Supported by NIH grant nos. NS19904 and GM63929, the R. P. Doherty-Welch Chair in Science (R.L.D.), and an National Research Service Award from the National Institute on Aging (S.E.M.).