P[acman]: A BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster

Science

Volumn 314, Issue 5806, 2006, Pages 1747-1751

  Venken, Koen J T ^a   He, Yuchun ^a   Hoskins, Roger A ^b   Bellen, Hugo J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CHROMOSOMES; DNA SEQUENCES; MUTAGENESIS;

BACTERIAL ARTIFICIAL CHROMOSOME (BAC); DROSOPHILA GENES; PLASMIDS; TRANSGENESIS;

GENETIC ENGINEERING;

DNA FRAGMENT;

BACTERIOPHAGE; CHROMOSOME; DNA; FLY; GENETIC ENGINEERING; GENETICALLY MODIFIED ORGANISM;

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BACTERIOPHAGE; CLONE; DROSOPHILA MELANOGASTER; GENE FUNCTION; GENE INSERTION; GENE MUTATION; GENE STRUCTURE; GENE TARGETING; GENETIC ANALYSIS; GENOME; MUTAGENESIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; TECHNOLOGY; TRANSGENICS;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CLONING, MOLECULAR; DNA REPAIR; DNA TRANSPOSABLE ELEMENTS; DROSOPHILA MELANOGASTER; GENE TRANSFER TECHNIQUES; GENES, INSECT; GENETIC VECTORS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PLASMIDS; RECOMBINATION, GENETIC; SIPHOVIRIDAE; TRANSGENES; TRANSPOSASES;

BACTERIA (MICROORGANISMS); DROSOPHILA MELANOGASTER;

EID: 33845698104     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1134426     Document Type: Article

References (26)

1. K. J. Venken, H. J. Bellen, Nat. Rev. Genet. 6, 167 (2005).
2. K. A. Matthews, T. C. Kaufman, W. M. Gelbart, Nat. Rev. Genet. 6, 179 (2005).
3. G. M. Rubin, A. C. Spradling, Science 218, 348 (1982).
4. E. Ryder, S. Russell, Brief. Function. Genom. Proteom. 2, 57 (2003).
5. N. Sternberg, Proc. Natl. Acad. Sci. U.S.A. 87, 103 (1990).
6. H. Shizuya et al. Proc. Natl. Acad. Sci. U.S.A. 89, 8794 (1992).
7. J. Wild, Z. Hradecna, W. Szybalski, Genome Res. 12, 1434 (2002).
8. N. G. Copeland, N. A. Jenkins, D. L. Court, Nat. Rev. Genet. 2, 769 (2001).
9. H. J. Bellen et al., Genetics 167, 761 (2004).
10. K. K. Norga et al., Curr. Biol. 13, 1388 (2003).
11. A. C. Groth, M. Fish, R. Nusse, M. P. Calos, Genetics 166, 1775 (2004).
12. W. Kimmerly et al., Genome Res. 6, 414 (1996).
13. R. A. Hoskins et al., Science 287, 2271 (2000).
14. M. D. Adams et al., Science 287, 2185 (2000).
15. S. E. Celniker et al., Genome Biol. 3, RESEARCH0079 (2002).
16. H. Jafar-Nejad, H. J. Bellen, Mol. Cell. Biol. 24, 8803 (2004).
17. E. C. Lee et al., Genomics 73, 56 (2001).
18. D. L. Court et al., Gene 315, 63 (2003).
19. X. Li, N. Lobo, C. A. Bauser, M. J. Fraser Jr., Mol. Genet. Genomics 266, 190 (2001).
20. G. Kotzamanis, C. Huxley, BMC Biotechnol. 4, 1 (2004).
21. H. M. Thorpe, M. C. Smith, Proc. Natl. Acad. Sci. U.S.A. 95, 5505 (1998).
22. A. L. Parks et al., Nat. Genet. 36, 288 (2004).
23. H. F. Xu et al., Mol. Genet. Genomics 276, 31 (2006).
24. D. A. Sorrell, A. F. Kolb, Biotechnol. Adv. 23, 431 (2005).
25. P. Verstreken et al., Neuron 47, 365 (2005).
26. R-F-2, EF106980. We thank the Bloomington Stock Center and Drosophila Genome Resource Center for fly stocks and plasmids, respectively; and M. Calos, J. Carlson, A. Celik, H.-T. Chao, K.-W. Choi, J. Clemens, N. Copeland, D. Court, C. Delidakis, M. Evans-Holm, D. Featherstone, M. Fraser, A. Handler, N. Jenkins, H. Kim, E. Lai, P. Liu, P. Ponsaerts, R. Mann, D. Schmucker, S. Speese, W. Szybalski, U. Tepass, L. Zipursky, and past and present members of the Bellen lab for flies, bacteria, plasmids, help, and/or stimulating discussions. H.J.B is an investigator with the Howard Hughes Medical Institute. This work was supported by NIH (grant GM067858-05) and the Howard Hughes Medical Institute. Plasmids are available through the Drosophila Genome Resource Center. Fly strains are available through the Bloomington Stock Center.