-
1
-
-
78649498609
-
High concentrations of anti-caspase-8 antibodies in Chilean patients with type 1 diabetes
-
Oyarzun A, Lera L, Codner E, et al. High concentrations of anti-caspase-8 antibodies in Chilean patients with type 1 diabetes. Immunobiology. 2011; 216: 208-12.
-
(2011)
Immunobiology
, vol.216
, pp. 208-212
-
-
Oyarzun, A.1
Lera, L.2
Codner, E.3
-
2
-
-
80052829380
-
Defective Differentiation of regulatory FoxP3(+) T Cells by small-intestinal dendritic cells in patients with type 1 diabetes
-
Badami E, Sorini C, Coccia M, et al. Defective Differentiation of regulatory FoxP3(+) T Cells by small-intestinal dendritic cells in patients with type 1 diabetes. Diabetes. 2011; 60: 2120-4.
-
(2011)
Diabetes
, vol.60
, pp. 2120-2124
-
-
Badami, E.1
Sorini, C.2
Coccia, M.3
-
3
-
-
83455224508
-
In Type 1 Diabetes Immunocompetent cells are defective in IL-16 secretion
-
Vendrame F, Cataldo D, Ciarlo L, et al. In Type 1 Diabetes Immunocompetent cells are defective in IL-16 secretion. Scand J Immunol. 2012; 75: 127-8.
-
(2012)
Scand J Immunol
, vol.75
, pp. 127-128
-
-
Vendrame, F.1
Cataldo, D.2
Ciarlo, L.3
-
4
-
-
79251640900
-
Innate immunity and the pathogenesis of type 1 diabetes
-
Grieco FA, Vendrame F, Spagnuolo I, et al. Innate immunity and the pathogenesis of type 1 diabetes. Semin Immunopathol. 2011; 33: 57-66.
-
(2011)
Semin Immunopathol
, vol.33
, pp. 57-66
-
-
Grieco, F.A.1
Vendrame, F.2
Spagnuolo, I.3
-
5
-
-
76549198972
-
Pathologic anatomy of pancreas in juvenile diabetes mellitus
-
Gepts W. Pathologic anatomy of pancreas in juvenile diabetes mellitus. Diabetes. 1965; 14: 619.
-
(1965)
Diabetes
, vol.14
, pp. 619
-
-
Gepts, W.1
-
6
-
-
78751662679
-
Type 1 diabetes etiology, immunology, and therapeutic strategies
-
Van Belle TL, Coppieters KT, Von Herrath MG. Type 1 diabetes etiology, immunology, and therapeutic strategies. Physiol Rev. 2011; 91: 79-118.
-
(2011)
Physiol Rev
, vol.91
, pp. 79-118
-
-
Van Belle, T.L.1
Coppieters, K.T.2
Von Herrath, M.G.3
-
7
-
-
77951884435
-
The long and winding road to understanding and conquering type 1 diabetes
-
Santamaria P. The long and winding road to understanding and conquering type 1 diabetes. Immunity. 2010; 32: 437-45.
-
(2010)
Immunity
, vol.32
, pp. 437-445
-
-
Santamaria, P.1
-
8
-
-
79955883244
-
Investigating the role of T-cell avidity and killing efficacy in relation to type 1 diabetes prediction
-
Khadra A, Pietropaolo M, Nepom GT, et al. Investigating the role of T-cell avidity and killing efficacy in relation to type 1 diabetes prediction. PLoS ONE. 2011; 6: e14796.
-
(2011)
PLoS ONE
, vol.6
-
-
Khadra, A.1
Pietropaolo, M.2
Nepom, G.T.3
-
9
-
-
79960956458
-
A novel triple mix radiobinding assay for the three ZnT8 (ZnT8-RWQ) autoantibody variants in children with newly diagnosed diabetes
-
Vaziri-Sani F, Delli AJ, Elding-Larsson H, et al. A novel triple mix radiobinding assay for the three ZnT8 (ZnT8-RWQ) autoantibody variants in children with newly diagnosed diabetes. J Immunol Methods. 2011; 371: 25-37.
-
(2011)
J Immunol Methods
, vol.371
, pp. 25-37
-
-
Vaziri-Sani, F.1
Delli, A.J.2
Elding-Larsson, H.3
-
10
-
-
84857392593
-
Rising incidence of type 1 diabetes is associated with altered immunophenotype at diagnosis
-
Long AE, Gillespie KM, Rokni S, et al. Rising incidence of type 1 diabetes is associated with altered immunophenotype at diagnosis. Diabetes. 2012; 61: 683-6.
-
(2012)
Diabetes
, vol.61
, pp. 683-686
-
-
Long, A.E.1
Gillespie, K.M.2
Rokni, S.3
-
11
-
-
18744385526
-
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope
-
Kent SC, Chen YH, Bregoli L, et al. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope. Nature. 2005; 435: 224-8.
-
(2005)
Nature
, vol.435
, pp. 224-228
-
-
Kent, S.C.1
Chen, Y.H.2
Bregoli, L.3
-
12
-
-
18744366947
-
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice
-
Nakayama M, Abiru N, Moriyama H, et al. Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature. 2005; 435: 220-3.
-
(2005)
Nature
, vol.435
, pp. 220-223
-
-
Nakayama, M.1
Abiru, N.2
Moriyama, H.3
-
13
-
-
79952193175
-
Suppression of dendritic cell activation by diabetes autoantigens linked to the cholera toxin B subunit
-
Odumosu O, Payne K, Baez I, et al. Suppression of dendritic cell activation by diabetes autoantigens linked to the cholera toxin B subunit. Immunobiology. 2011; 216: 447-56.
-
(2011)
Immunobiology
, vol.216
, pp. 447-456
-
-
Odumosu, O.1
Payne, K.2
Baez, I.3
-
14
-
-
50549103960
-
T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies
-
Marttila J, Huttunen S, Vaarala O, et al. T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies. J Autoimmun. 2008; 31: 142-8.
-
(2008)
J Autoimmun
, vol.31
, pp. 142-148
-
-
Marttila, J.1
Huttunen, S.2
Vaarala, O.3
-
15
-
-
0034652317
-
Early expression of antiinsulin autoantibodies of humans and the NOD mouse evidence for early determination of subsequent diabetes
-
Yu LP, Robles DT, Abiru N, et al. Early expression of antiinsulin autoantibodies of humans and the NOD mouse evidence for early determination of subsequent diabetes. Proc Natl Acad Sci USA. 2000; 97: 1701-6.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1701-1706
-
-
Yu, L.P.1
Robles, D.T.2
Abiru, N.3
-
16
-
-
84884592691
-
Antigen-based vaccination and prevention of type 1 diabetes
-
Harrison LC, Wentworth JM, Zhang Y, et al. Antigen-based vaccination and prevention of type 1 diabetes. Curr Diabetes Rep. 2013; 13: 616-23.
-
(2013)
Curr Diabetes Rep
, vol.13
, pp. 616-623
-
-
Harrison, L.C.1
Wentworth, J.M.2
Zhang, Y.3
-
17
-
-
67650360252
-
Therapy with GAD in diabetes
-
Ludvigsson J. Therapy with GAD in diabetes. Diabetes Metab Res. 2009; 25: 307-15.
-
(2009)
Diabetes Metab Res
, vol.25
, pp. 307-315
-
-
Ludvigsson, J.1
-
18
-
-
0027409043
-
Association of GAD-65, but not of GAD-67, with the golgi-complex of transfected chinese-hamster ovary cells mediated by the n-terminal region
-
Solimena M, Aggujaro D, MuntzeL C, et al. Association of GAD-65, but not of GAD-67, with the golgi-complex of transfected chinese-hamster ovary cells mediated by the n-terminal region. Proc Natl Acad Sci USA. 1993; 90: 3073-7.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3073-3077
-
-
Solimena, M.1
Aggujaro, D.2
MuntzeL, C.3
-
19
-
-
0027450794
-
Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic-acid decarboxylase
-
Hagopian WA, Chelsen BM, Karlsen AE, et al. Autoantibodies in IDDM primarily recognize the 65, 000-M(r) rather than the 67, 000-M(r) isoform of glutamic-acid decarboxylase. Diabetes. 1993; 42: 631-6.
-
(1993)
Diabetes
, vol.42
, pp. 631-636
-
-
Hagopian, W.A.1
Chelsen, B.M.2
Karlsen, A.E.3
-
20
-
-
79954497707
-
An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes
-
Jayakrishnan B, Hoke DE, Langendorf CG, et al. An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes. PLoS ONE. 2011; 6: e18411.
-
(2011)
PLoS ONE
, vol.6
-
-
Jayakrishnan, B.1
Hoke, D.E.2
Langendorf, C.G.3
-
21
-
-
80052666659
-
Immunoglobulin subclass profiles of anti-idiotypic antibodies to GAD65Ab differ between type 1 diabetes patients and healthy individuals
-
Oak S, Radtke J, Torn C, et al. Immunoglobulin subclass profiles of anti-idiotypic antibodies to GAD65Ab differ between type 1 diabetes patients and healthy individuals. Scand J Immunol. 2011; 74: 363-7.
-
(2011)
Scand J Immunol
, vol.74
, pp. 363-367
-
-
Oak, S.1
Radtke, J.2
Torn, C.3
-
22
-
-
84863165531
-
Anti-Idiotypic Antibody Specific to GAD65 autoantibody prevents type 1 diabetes in the NOD mouse
-
Wang X, Zhang A, Liu Y, et al. Anti-Idiotypic Antibody Specific to GAD65 autoantibody prevents type 1 diabetes in the NOD mouse. PLoS ONE. 2012; 7: e32515.
-
(2012)
PLoS ONE
, vol.7
-
-
Wang, X.1
Zhang, A.2
Liu, Y.3
-
23
-
-
80053085802
-
Combining antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted beta-cells in diabetic NOD mice
-
Tian J, Dang H, Kaufman DL. Combining antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted beta-cells in diabetic NOD mice. PLoS ONE. 2011; 6: e25337.
-
(2011)
PLoS ONE
, vol.6
-
-
Tian, J.1
Dang, H.2
Kaufman, D.L.3
-
24
-
-
84856564903
-
GAD65 Antigen therapy in recently diagnosed type 1 diabetes mellitus
-
Ludvigsson J, Krisky D, Casas R, et al. GAD65 Antigen therapy in recently diagnosed type 1 diabetes mellitus. New Engl J Med. 2012; 366: 433-42.
-
(2012)
New Engl J Med
, vol.366
, pp. 433-442
-
-
Ludvigsson, J.1
Krisky, D.2
Casas, R.3
-
25
-
-
84881374695
-
The clinical and immunological significance of GAD-specific autoantibody and 1-cell responses in type 1 diabetes
-
Boettler T, Pagni PP, Jaffe R, et al. The clinical and immunological significance of GAD-specific autoantibody and 1-cell responses in type 1 diabetes. J Autoimmun. 2013; 44: 40-8.
-
(2013)
J Autoimmun
, vol.44
, pp. 40-48
-
-
Boettler, T.1
Pagni, P.P.2
Jaffe, R.3
-
26
-
-
1642546578
-
Insulinoma-Associated Protein IA-2, a vesicle transmembrane protein, genetically interacts with UNC-31 CAPS and affects neurosecretion in caenorhabditis elegans
-
Cai T, Fukushige T, Notkins AL, et al. Insulinoma-Associated Protein IA-2, a vesicle transmembrane protein, genetically interacts with UNC-31 CAPS and affects neurosecretion in caenorhabditis elegans. J Neurosci. 2004; 24: 3115-24.
-
(2004)
J Neurosci
, vol.24
, pp. 3115-3124
-
-
Cai, T.1
Fukushige, T.2
Notkins, A.L.3
-
27
-
-
0032964798
-
Antoantigens IA-2 and GAD in type I (insulin-dependent) diabetes
-
Leslie R, Atkinson MA, Notkins AL. Antoantigens IA-2 and GAD in type I (insulin-dependent) diabetes. Diabetologia. 1999; 42: 3-14.
-
(1999)
Diabetologia
, vol.42
, pp. 3-14
-
-
Leslie, R.1
Atkinson, M.A.2
Notkins, A.L.3
-
28
-
-
67649546999
-
Insulinoma-associated protein 2-deficient mice develop severe forms of diabetes induced by multiple low doses of streptozotocin
-
Nakajima K, Wu G, Takeyama N, et al. Insulinoma-associated protein 2-deficient mice develop severe forms of diabetes induced by multiple low doses of streptozotocin. Int J Mol Med. 2009; 24: 23-7.
-
(2009)
Int J Mol Med
, vol.24
, pp. 23-27
-
-
Nakajima, K.1
Wu, G.2
Takeyama, N.3
-
29
-
-
74249087709
-
Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes non insulin requiring autoimmune diabetes (NIRAD) 4
-
Lampasona V, Petrone A, Tiberti C, et al. Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes non insulin requiring autoimmune diabetes (NIRAD) 4. Diabetes Care. 2010; 33: 104-8.
-
(2010)
Diabetes Care
, vol.33
, pp. 104-108
-
-
Lampasona, V.1
Petrone, A.2
Tiberti, C.3
-
30
-
-
79956218486
-
Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8
-
Dang M, Rockell J, Wagner R, et al. Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8. J Immunol. 2011; 186: 6056-63.
-
(2011)
J Immunol
, vol.186
, pp. 6056-6063
-
-
Dang, M.1
Rockell, J.2
Wagner, R.3
-
31
-
-
84871682813
-
Antigenicity and epitope specificity of ZnT8 autoantibodies in type 1 diabetes
-
Skarstrand H, Lernmark A, Vaziri-Sani F. Antigenicity and epitope specificity of ZnT8 autoantibodies in type 1 diabetes. Scand J Immunol. 2013; 77: 21-9.
-
(2013)
Scand J Immunol
, vol.77
, pp. 21-29
-
-
Skarstrand, H.1
Lernmark, A.2
Vaziri-Sani, F.3
-
32
-
-
4344665860
-
Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules
-
Chimienti F, Devergnas S, Favier A, et al. Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules. Diabetes. 2004; 53: 2330-7.
-
(2004)
Diabetes
, vol.53
, pp. 2330-2337
-
-
Chimienti, F.1
Devergnas, S.2
Favier, A.3
-
33
-
-
36749011882
-
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes
-
Wenzlau JM, Juhl K, Yu L, et al. The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci USA. 2007; 104: 17040-5.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 17040-17045
-
-
Wenzlau, J.M.1
Juhl, K.2
Yu, L.3
-
34
-
-
84875259796
-
Identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from zinc transporter 8
-
Li S, Li H, Chen B, et al. Identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from zinc transporter 8. Vaccine. 2013; 31: 1610-5.
-
(2013)
Vaccine
, vol.31
, pp. 1610-1615
-
-
Li, S.1
Li, H.2
Chen, B.3
-
35
-
-
84856775181
-
The role of autoantibodies to zinc transporter 8 in prediction of type 1 diabetes in relatives: lessons from the European nicotinamide diabetes intervention trial (ENDIT) Cohort
-
Long AE, Gooneratne AT, Rokni S, et al. The role of autoantibodies to zinc transporter 8 in prediction of type 1 diabetes in relatives: lessons from the European nicotinamide diabetes intervention trial (ENDIT) Cohort. J Clin Endocr Metab. 2012; 97: 632-7.
-
(2012)
J Clin Endocr Metab
, vol.97
, pp. 632-637
-
-
Long, A.E.1
Gooneratne, A.T.2
Rokni, S.3
-
36
-
-
64649084572
-
The A-chain of insulin is a hot-spot for CD4(+) T cell epitopes in human type 1 diabetes
-
Mannering SI, Pang SH, Williamson NA, et al. The A-chain of insulin is a hot-spot for CD4(+) T cell epitopes in human type 1 diabetes. Clin Exp Immunol. 2009; 156: 226-31.
-
(2009)
Clin Exp Immunol
, vol.156
, pp. 226-231
-
-
Mannering, S.I.1
Pang, S.H.2
Williamson, N.A.3
-
37
-
-
80054698474
-
Immunomodulation and regeneration of islet beta cells by cytokines in autoimmune type 1 diabetes
-
Singh B, Nikoopour E, Huszarik K, et al. Immunomodulation and regeneration of islet beta cells by cytokines in autoimmune type 1 diabetes. J Interf Cytok Res. 2011; 31: 711-9.
-
(2011)
J Interf Cytok Res
, vol.31
, pp. 711-719
-
-
Singh, B.1
Nikoopour, E.2
Huszarik, K.3
-
39
-
-
79961170586
-
A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice
-
Lin MS, Tse HM, Delmastro MM, et al. A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice. Immunol Res. 2011; 50: 213-20.
-
(2011)
Immunol Res
, vol.50
, pp. 213-220
-
-
Lin, M.S.1
Tse, H.M.2
Delmastro, M.M.3
-
40
-
-
0036268008
-
Regulatory natural killer T cells protect against spontaneous and recurrent type 1 diabetes
-
Sharif S, Arreaza GA, Zucker P, et al. Regulatory natural killer T cells protect against spontaneous and recurrent type 1 diabetes. Ann N Y Acad Sci. 2002; 958: 77-88.
-
(2002)
Ann N Y Acad Sci
, vol.958
, pp. 77-88
-
-
Sharif, S.1
Arreaza, G.A.2
Zucker, P.3
-
41
-
-
77955610171
-
Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic mice
-
Ruffner MA, Robbins PD. Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic mice. PLoS ONE. 2010; 5: e11848.
-
(2010)
PLoS ONE
, vol.5
-
-
Ruffner, M.A.1
Robbins, P.D.2
-
42
-
-
79955968277
-
IL-10-conditioned dendritic cells prevent autoimmune diabetes in NOD and humanized HLA-DQ8 RIP-B7.1 mice
-
Tai NW, Yasuda H, Xiang YF, et al. IL-10-conditioned dendritic cells prevent autoimmune diabetes in NOD and humanized HLA-DQ8 RIP-B7.1 mice. Clin Immunol. 2011; 139: 336-49.
-
(2011)
Clin Immunol
, vol.139
, pp. 336-349
-
-
Tai, N.W.1
Yasuda, H.2
Xiang, Y.F.3
-
43
-
-
80052465164
-
T-cell vaccination leads to suppression of intrapancreatic Th17 cells through Stat3-mediated ROR gamma t inhibition in autoimmune diabetes
-
Wang M, Yang L, Sheng XY, et al. T-cell vaccination leads to suppression of intrapancreatic Th17 cells through Stat3-mediated ROR gamma t inhibition in autoimmune diabetes. Cell Res. 2011; 21: 1358-69.
-
(2011)
Cell Res
, vol.21
, pp. 1358-1369
-
-
Wang, M.1
Yang, L.2
Sheng, X.Y.3
-
44
-
-
0032964001
-
Type I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease
-
Azar ST, Tamim H, Beyhum HN, et al. Type I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease. Clin Diagn Lab Immun. 1999; 6: 306-10.
-
(1999)
Clin Diagn Lab Immun
, vol.6
, pp. 306-310
-
-
Azar, S.T.1
Tamim, H.2
Beyhum, H.N.3
-
45
-
-
77958136352
-
Cutting edge increased IL-17-secreting T cells in children with new-onset type 1 diabetes
-
Marwaha AK, Crome SQ, Panagiotopoulos C, et al. Cutting edge increased IL-17-secreting T cells in children with new-onset type 1 diabetes. J Immunol. 2010; 185: 3814-8.
-
(2010)
J Immunol
, vol.185
, pp. 3814-3818
-
-
Marwaha, A.K.1
Crome, S.Q.2
Panagiotopoulos, C.3
-
46
-
-
45249097325
-
Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus Implications for Th17-mediated inflammation in auto-immunity
-
Wong CK, Lit LCW, Tam LS, et al. Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus Implications for Th17-mediated inflammation in auto-immunity. Clin Immunol. 2008; 127: 385-93.
-
(2008)
Clin Immunol
, vol.127
, pp. 385-393
-
-
Wong, C.K.1
Lit, L.C.W.2
Tam, L.S.3
-
47
-
-
72949107811
-
Translational Mini-Review Series on Th17 Cells: function and regulation of human T helper 17 cells in health and disease
-
Crome SQ, Wang AY, Levings MK. Translational Mini-Review Series on Th17 Cells: function and regulation of human T helper 17 cells in health and disease. Clin Exp Immunol. 2010; 159: 109-19.
-
(2010)
Clin Exp Immunol
, vol.159
, pp. 109-119
-
-
Crome, S.Q.1
Wang, A.Y.2
Levings, M.K.3
-
48
-
-
84877011245
-
Loss of the balance between CD4(+)Foxp3(+) regulatory T cells and CD4(+)IL17A(+) Th17 cells in patients with type 1 diabetes
-
Ryba-Stanislawowska M, Skrzypkowska M, Mysliwiec M, et al. Loss of the balance between CD4(+)Foxp3(+) regulatory T cells and CD4(+)IL17A(+) Th17 cells in patients with type 1 diabetes. Hum Immunol. 2013; 74: 701-7.
-
(2013)
Hum Immunol
, vol.74
, pp. 701-707
-
-
Ryba-Stanislawowska, M.1
Skrzypkowska, M.2
Mysliwiec, M.3
-
49
-
-
84876741481
-
B7-H4.Ig inhibits the development of Type 1 diabetes by regulating Th17 cells in NOD mice
-
Lee IF, Wang XJ, Hao JQ, et al. B7-H4.Ig inhibits the development of Type 1 diabetes by regulating Th17 cells in NOD mice. Cell Immunol. 2013; 282: 1-8.
-
(2013)
Cell Immunol
, vol.282
, pp. 1-8
-
-
Lee, I.F.1
Wang, X.J.2
Hao, J.Q.3
-
50
-
-
77956398549
-
IL-17 immunity in human type 1 diabetes
-
Honkanen J, Nieminen JK, Gao R, et al. IL-17 immunity in human type 1 diabetes. J Immunol. 2010; 185: 1959-67.
-
(2010)
J Immunol
, vol.185
, pp. 1959-1967
-
-
Honkanen, J.1
Nieminen, J.K.2
Gao, R.3
-
51
-
-
67650650890
-
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
-
Bending D, De La Pena H, Veldhoen M, et al. Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J Clin Invest. 2009; 119: 565-72.
-
(2009)
J Clin Invest
, vol.119
, pp. 565-572
-
-
Bending, D.1
De La Pena, H.2
Veldhoen, M.3
-
52
-
-
0016812372
-
Suppressor T-cells in mice made unresponsive to skin allografts
-
Kilshaw PJ, Brent L, Pinto M. Suppressor T-cells in mice made unresponsive to skin allografts. Nature. 1975; 255: 489-91.
-
(1975)
Nature
, vol.255
, pp. 489-491
-
-
Kilshaw, P.J.1
Brent, L.2
Pinto, M.3
-
53
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi S, Yamaguchi T, Nomura T, et al. Regulatory T cells and immune tolerance. Cell. 2008; 133: 775-87.
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
-
54
-
-
84879356078
-
Foxp3(+) regulatory T cells in mouse models of type 1 diabetes
-
Petzold C, Riewaldt J, Watts D, et al. Foxp3(+) regulatory T cells in mouse models of type 1 diabetes. J Diabetes Res. 2013; 2013: 940710.
-
(2013)
J Diabetes Res
, vol.2013
, pp. 940710
-
-
Petzold, C.1
Riewaldt, J.2
Watts, D.3
-
55
-
-
84870981578
-
Dietary gluten alters the balance of pro-inflammatory and anti-inflammatory cytokines in T cells of BALB/c mice
-
Antvorskov JC, Fundova P, Buschard K, et al. Dietary gluten alters the balance of pro-inflammatory and anti-inflammatory cytokines in T cells of BALB/c mice. Immunology. 2013; 138: 23-33.
-
(2013)
Immunology
, vol.138
, pp. 23-33
-
-
Antvorskov, J.C.1
Fundova, P.2
Buschard, K.3
-
56
-
-
84859864752
-
Downregulation of TGF-beta RII in Teffector cells leads to increased resistance to TGF-beta-mediated suppression of autoimmune responses in type I diabetes
-
Kawamoto K, Pahuja A, Nettles A, et al. Downregulation of TGF-beta RII in Teffector cells leads to increased resistance to TGF-beta-mediated suppression of autoimmune responses in type I diabetes. Autoimmunity. 2012; 45: 310-9.
-
(2012)
Autoimmunity
, vol.45
, pp. 310-319
-
-
Kawamoto, K.1
Pahuja, A.2
Nettles, A.3
-
57
-
-
84876837169
-
Excessive Th1 responses due to the absence of TGF-beta signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis
-
Ishigame H, Zenewicz LA, Sanjabi S, et al. Excessive Th1 responses due to the absence of TGF-beta signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis. Proc Natl Acad Sci USA. 2013; 110: 6961-6.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6961-6966
-
-
Ishigame, H.1
Zenewicz, L.A.2
Sanjabi, S.3
-
58
-
-
33744517332
-
IL-10-deficiency unmasks unique immune system defects and reveals differential regulation of organ-specific autoimmunity in non-obese diabetic mice
-
Rajagopalan G, Kudva YC, Sen MM, et al. IL-10-deficiency unmasks unique immune system defects and reveals differential regulation of organ-specific autoimmunity in non-obese diabetic mice. Cytokine. 2006; 34: 85-95.
-
(2006)
Cytokine
, vol.34
, pp. 85-95
-
-
Rajagopalan, G.1
Kudva, Y.C.2
Sen, M.M.3
-
59
-
-
84857193362
-
The composition and signaling of the IL-35 receptor are unconventional
-
Collison LW, Delgoffe GM, Guy CS, et al. The composition and signaling of the IL-35 receptor are unconventional. Nat Immunol. 2012; 13: 115-290.
-
(2012)
Nat Immunol
, vol.13
, pp. 115-290
-
-
Collison, L.W.1
Delgoffe, G.M.2
Guy, C.S.3
-
60
-
-
84861851646
-
Prevention of autoimmune diabetes by ectopic pancreatic beta-cell expression of interleukin-35
-
Bettini M, Castellaw AH, Lennon GP, et al. Prevention of autoimmune diabetes by ectopic pancreatic beta-cell expression of interleukin-35. Diabetes. 2012; 61: 1519-26.
-
(2012)
Diabetes
, vol.61
, pp. 1519-1526
-
-
Bettini, M.1
Castellaw, A.H.2
Lennon, G.P.3
-
61
-
-
84880033192
-
CD4(+)CD45RA(-)FoxP3(high) activated regulatory T cells are functionally impaired and related to residual insulin-secreting capacity in patients with type 1 diabetes
-
Haseda F, Imagawa A, Murase-Mishiba Y, et al. CD4(+)CD45RA(-)FoxP3(high) activated regulatory T cells are functionally impaired and related to residual insulin-secreting capacity in patients with type 1 diabetes. Clin Exp Immunol. 2013; 173: 207-16.
-
(2013)
Clin Exp Immunol
, vol.173
, pp. 207-216
-
-
Haseda, F.1
Imagawa, A.2
Murase-Mishiba, Y.3
-
63
-
-
84876428386
-
The role of different subsets of regulatory T cells in immunopathogenesis of rheumatoid arthritis
-
Gol-Ara M, Jadidi-Niaragh F, Sadria R, et al. The role of different subsets of regulatory T cells in immunopathogenesis of rheumatoid arthritis. Arthritis. 2012; 2012: 805875.
-
(2012)
Arthritis
, vol.2012
, pp. 805875
-
-
Gol-Ara, M.1
Jadidi-Niaragh, F.2
Sadria, R.3
-
64
-
-
84879831952
-
Advances in distinguishing natural from induced Foxp3(+) regulatory T cells
-
Lin XH, Chen MG, Liu Y, et al. Advances in distinguishing natural from induced Foxp3(+) regulatory T cells. Int J Clin Exp Pathol. 2013; 6: 116-23.
-
(2013)
Int J Clin Exp Pathol
, vol.6
, pp. 116-123
-
-
Lin, X.H.1
Chen, M.G.2
Liu, Y.3
-
65
-
-
78649938754
-
The type of responder T-cell has a significant impact in a human in vitro suppression assay
-
Jana S, Campbell H, Woodliff J, et al. The type of responder T-cell has a significant impact in a human in vitro suppression assay. PLoS ONE. 2010; 5: e15154.
-
(2010)
PLoS ONE
, vol.5
-
-
Jana, S.1
Campbell, H.2
Woodliff, J.3
-
66
-
-
67650003971
-
Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner
-
Tonkin DR, Haskins K. Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner. Eur J Immunol. 2009; 39: 1313-22.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1313-1322
-
-
Tonkin, D.R.1
Haskins, K.2
-
67
-
-
2942692039
-
CD25(+) CD4(+) T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
-
Tarbell KV, Yamazaki S, Olson K, et al. CD25(+) CD4(+) T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med. 2004; 199: 1467-77.
-
(2004)
J Exp Med
, vol.199
, pp. 1467-1477
-
-
Tarbell, K.V.1
Yamazaki, S.2
Olson, K.3
-
68
-
-
84885093230
-
Differential response of regulatory and conventional CD4(+) lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action?
-
Li L, Nishio J, van Maurik A, et al. Differential response of regulatory and conventional CD4(+) lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action? J Immunol. 2013; 191: 3694-704.
-
(2013)
J Immunol
, vol.191
, pp. 3694-3704
-
-
Li, L.1
Nishio, J.2
van Maurik, A.3
-
69
-
-
77956257716
-
IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
-
Grinberg-Bleyer Y, Baeyens A, You S, et al. IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells. J Exp Med. 2010; 207: 1871-8.
-
(2010)
J Exp Med
, vol.207
, pp. 1871-1878
-
-
Grinberg-Bleyer, Y.1
Baeyens, A.2
You, S.3
-
70
-
-
84873749432
-
IL-2 promotes the function of memory-like autoregulatory CD8+T cells but suppresses their development via FoxP3+Treg cells
-
Shameli A, Yamanouchi J, Tsai S, et al. IL-2 promotes the function of memory-like autoregulatory CD8+T cells but suppresses their development via FoxP3+Treg cells. Eur J Immunol. 2013; 43: 394-403.
-
(2013)
Eur J Immunol
, vol.43
, pp. 394-403
-
-
Shameli, A.1
Yamanouchi, J.2
Tsai, S.3
-
71
-
-
84884181617
-
Immune regulation in T1D and T2D: prospective role of Foxp3+ treg cells in disease pathogenesis and treatment
-
Kornete M, Mason ES, Piccirillo CA. Immune regulation in T1D and T2D: prospective role of Foxp3+ treg cells in disease pathogenesis and treatment. Front Endocrinol. 2013; 4: 76.
-
(2013)
Front Endocrinol
, vol.4
, pp. 76
-
-
Kornete, M.1
Mason, E.S.2
Piccirillo, C.A.3
-
72
-
-
67349143066
-
Genetic association of HLA DQB1 with CD4+CD25+ (high) T-cell apoptosis in type 1 diabetes
-
Glisic S, Klinker M, Waukau J, et al. Genetic association of HLA DQB1 with CD4+CD25+ (high) T-cell apoptosis in type 1 diabetes. Genes Immun. 2009; 10: 334-40.
-
(2009)
Genes Immun
, vol.10
, pp. 334-340
-
-
Glisic, S.1
Klinker, M.2
Waukau, J.3
-
73
-
-
77949265942
-
Inducible regulatory T cells (iTregs) from recent-onset type 1 diabetes subjects show increased in vitro suppression and higher ITCH levels compared with controls
-
Glisic S, Ehlenbach S, Jailwala P, et al. Inducible regulatory T cells (iTregs) from recent-onset type 1 diabetes subjects show increased in vitro suppression and higher ITCH levels compared with controls. Cell Tissue Res. 2010; 339: 585-95.
-
(2010)
Cell Tissue Res
, vol.339
, pp. 585-595
-
-
Glisic, S.1
Ehlenbach, S.2
Jailwala, P.3
-
74
-
-
84881023892
-
Clinical application of regulatory T cells in type 1 diabetes
-
Marek-Trzonkowska N, Mysliwec M, Siebert J, et al. Clinical application of regulatory T cells in type 1 diabetes. Pediatr Diabetes. 2013; 14: 322-32.
-
(2013)
Pediatr Diabetes
, vol.14
, pp. 322-332
-
-
Marek-Trzonkowska, N.1
Mysliwec, M.2
Siebert, J.3
-
75
-
-
77950867022
-
Numerical defects in CD8(+)CD28(-) T-suppressor lymphocyte population in patients with type 1 diabetes mellitus and multiple sclerosis
-
Mikulkova Z, Praksova P, Stourac P, et al. Numerical defects in CD8(+)CD28(-) T-suppressor lymphocyte population in patients with type 1 diabetes mellitus and multiple sclerosis. Cell Immunol. 2010; 262: 75-9.
-
(2010)
Cell Immunol
, vol.262
, pp. 75-79
-
-
Mikulkova, Z.1
Praksova, P.2
Stourac, P.3
-
76
-
-
0033039278
-
Responses of CD8(+) T cells to intracellular bacteria
-
Harty JT, Bevan MJ. Responses of CD8(+) T cells to intracellular bacteria. Curr Opin Immunol. 1999; 11: 89-93.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 89-93
-
-
Harty, J.T.1
Bevan, M.J.2
-
77
-
-
84875981114
-
IL-21 promotes CD8(+) ctl activity via the transcription factor T-bet
-
Sutherland A, Joller N, Michaud M, et al. IL-21 promotes CD8(+) ctl activity via the transcription factor T-bet. J Immunol. 2013; 190: 3977-84.
-
(2013)
J Immunol
, vol.190
, pp. 3977-3984
-
-
Sutherland, A.1
Joller, N.2
Michaud, M.3
-
78
-
-
0033840544
-
The critical role of CD40 CD40L in the CD4-dependent generation of CD8(+) T cell immunity
-
Clarke S. The critical role of CD40 CD40L in the CD4-dependent generation of CD8(+) T cell immunity. J Leukocyte Biol. 2000; 67: 607-14.
-
(2000)
J Leukocyte Biol
, vol.67
, pp. 607-614
-
-
Clarke, S.1
-
79
-
-
84872352675
-
Prevention or acceleration of type 1 diabetes by viruses
-
Ghazarian L, Diana J, Simoni Y, et al. Prevention or acceleration of type 1 diabetes by viruses. Cell Mol Life Sci. 2013; 70: 239-55.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 239-255
-
-
Ghazarian, L.1
Diana, J.2
Simoni, Y.3
-
80
-
-
67649207839
-
GAD65-Specific Cytotoxic T lymphocytes mediate beta-cell death and loss of function
-
Rasche S, Busick RY, Quinn A. GAD65-Specific Cytotoxic T lymphocytes mediate beta-cell death and loss of function. Rev Diabet Stud. 2009; 6: 43-53.
-
(2009)
Rev Diabet Stud
, vol.6
, pp. 43-53
-
-
Rasche, S.1
Busick, R.Y.2
Quinn, A.3
-
81
-
-
0027367830
-
Major histocompatibility complex class-i molecules are required for the development of insulitis in nonobese diabetic mice
-
Katz J, Benoist C, Mathis D. Major histocompatibility complex class-i molecules are required for the development of insulitis in nonobese diabetic mice. Eur J Immunol. 1993; 23: 3358-60.
-
(1993)
Eur J Immunol
, vol.23
, pp. 3358-3360
-
-
Katz, J.1
Benoist, C.2
Mathis, D.3
-
82
-
-
84857189975
-
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes
-
Bulek AM, Cole DK, Skowera A, et al. Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat Immunol. 2012; 13: 283-1521.
-
(2012)
Nat Immunol
, vol.13
, pp. 283-1521
-
-
Bulek, A.M.1
Cole, D.K.2
Skowera, A.3
-
83
-
-
79952135500
-
The potential of multimer technologies in type 1 diabetes prediction strategies
-
Fierabracci A. The potential of multimer technologies in type 1 diabetes prediction strategies. Diabetes Metab Res. 2011; 27: 216-29.
-
(2011)
Diabetes Metab Res
, vol.27
, pp. 216-229
-
-
Fierabracci, A.1
-
84
-
-
84856825977
-
Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
-
Coppieters KT, Dotta F, Amirian N, et al. Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. J Exp Med. 2012; 209: 51-60.
-
(2012)
J Exp Med
, vol.209
, pp. 51-60
-
-
Coppieters, K.T.1
Dotta, F.2
Amirian, N.3
-
85
-
-
84880021592
-
Induction of autoimmune diabetes in non-obese diabetic mice requires interleukin-21-dependent activation of autoreactive CD8(+) T cells
-
Chen XL, Bobbala D, Rodriguez GM, et al. Induction of autoimmune diabetes in non-obese diabetic mice requires interleukin-21-dependent activation of autoreactive CD8(+) T cells. Clin Exp Immunol. 2013; 173: 184-94.
-
(2013)
Clin Exp Immunol
, vol.173
, pp. 184-194
-
-
Chen, X.L.1
Bobbala, D.2
Rodriguez, G.M.3
-
86
-
-
33845995044
-
SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes
-
Barral AM, Thomas HE, Ling EM, et al. SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes. J Autoimmun. 2006; 27: 166-73.
-
(2006)
J Autoimmun
, vol.27
, pp. 166-173
-
-
Barral, A.M.1
Thomas, H.E.2
Ling, E.M.3
-
87
-
-
77957855176
-
HLA-E restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes
-
Jiang H, Canfield SM, Gallagher MP, et al. HLA-E restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes. J Clin Invest. 2010; 120: 3641-50.
-
(2010)
J Clin Invest
, vol.120
, pp. 3641-3650
-
-
Jiang, H.1
Canfield, S.M.2
Gallagher, M.P.3
-
88
-
-
67651099236
-
Change you can B(cell)eive in recent progress confirms a critical role for B cells in type 1 diabetes
-
O'Neill SK, Liu E, Cambier JC. Change you can B(cell)eive in recent progress confirms a critical role for B cells in type 1 diabetes. Curr Opin Endocrinol. 2009; 16: 293-8.
-
(2009)
Curr Opin Endocrinol
, vol.16
, pp. 293-298
-
-
O'Neill, S.K.1
Liu, E.2
Cambier, J.C.3
-
89
-
-
77649146706
-
Emerging roles for B lymphocytes in Type 1 diabetes
-
Cox SL, Silveira PA. Emerging roles for B lymphocytes in Type 1 diabetes. Expert Rev Clin Immunol. 2009; 5: 311-24.
-
(2009)
Expert Rev Clin Immunol
, vol.5
, pp. 311-324
-
-
Cox, S.L.1
Silveira, P.A.2
-
90
-
-
84859835474
-
Protective role of anti-idiotypic antibodies in autoimmunity - lessons for type 1 diabetes
-
Hampe CS. Protective role of anti-idiotypic antibodies in autoimmunity - lessons for type 1 diabetes. Autoimmunity. 2012; 45: 320-31.
-
(2012)
Autoimmunity
, vol.45
, pp. 320-331
-
-
Hampe, C.S.1
-
91
-
-
4644225746
-
Investigation of the role of B-cells in type 1 diabetes in the NOD mouse
-
Wong FS, Wen L, Tang M, et al. Investigation of the role of B-cells in type 1 diabetes in the NOD mouse. Diabetes. 2004; 53: 2581-7.
-
(2004)
Diabetes
, vol.53
, pp. 2581-2587
-
-
Wong, F.S.1
Wen, L.2
Tang, M.3
-
92
-
-
42449104350
-
B-cells promote intra-islet CD8+ cytotoxic T-cell survival to enhance type 1 diabetes
-
Brodie GM, Wallberg M, Santamaria P, et al. B-cells promote intra-islet CD8+ cytotoxic T-cell survival to enhance type 1 diabetes. Diabetes. 2008; 57: 909-17.
-
(2008)
Diabetes
, vol.57
, pp. 909-917
-
-
Brodie, G.M.1
Wallberg, M.2
Santamaria, P.3
-
93
-
-
77955922605
-
alpha(4)beta(7) integrin/MAdCAM-1 adhesion pathway is crucial for B cell migration into pancreatic lymph nodes in nonobese diabetic mice
-
Xu BH, Cook RE, Michie SA. alpha(4)beta(7) integrin/MAdCAM-1 adhesion pathway is crucial for B cell migration into pancreatic lymph nodes in nonobese diabetic mice. J Autoimmun. 2010; 35: 124-9.
-
(2010)
J Autoimmun
, vol.35
, pp. 124-129
-
-
Xu, B.H.1
Cook, R.E.2
Michie, S.A.3
-
94
-
-
0030969531
-
B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice
-
Noorchashm H, Noorchashm N, Kern J, et al. B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice. Diabetes. 1997; 46: 941-6.
-
(1997)
Diabetes
, vol.46
, pp. 941-946
-
-
Noorchashm, H.1
Noorchashm, N.2
Kern, J.3
-
95
-
-
84883360314
-
Combination treatment with anti-CD20 and oral anti-CD3 prevents and reverses autoimmune diabetes
-
Hu CY, Ding HN, Zhang XJ, et al. Combination treatment with anti-CD20 and oral anti-CD3 prevents and reverses autoimmune diabetes. Diabetes. 2013; 62: 2849-58.
-
(2013)
Diabetes
, vol.62
, pp. 2849-2858
-
-
Hu, C.Y.1
Ding, H.N.2
Zhang, X.J.3
-
96
-
-
0035807589
-
Brief report - development of type 1 diabetes despite severe hereditary B-cell deficiency
-
Martin S, Wolf-Eichbaum D, Duinkerken G, et al. Brief report - development of type 1 diabetes despite severe hereditary B-cell deficiency. New Engl J Med. 2001; 345: 1036-40.
-
(2001)
New Engl J Med
, vol.345
, pp. 1036-1040
-
-
Martin, S.1
Wolf-Eichbaum, D.2
Duinkerken, G.3
-
97
-
-
62749129435
-
Role of innate immunity in triggering and tuning of autoimmune diabetes
-
Kim HS, Lee MS. Role of innate immunity in triggering and tuning of autoimmune diabetes. Curr Mol Med. 2009; 9: 30-44.
-
(2009)
Curr Mol Med
, vol.9
, pp. 30-44
-
-
Kim, H.S.1
Lee, M.S.2
-
98
-
-
77954760110
-
Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes
-
Jobim M, Chagastelles P, Salim PH, et al. Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes. Hum Immunol. 2010; 71: 799-803.
-
(2010)
Hum Immunol
, vol.71
, pp. 799-803
-
-
Jobim, M.1
Chagastelles, P.2
Salim, P.H.3
-
99
-
-
33847053237
-
Altered natural killer cells in type 1 diabetic patients
-
Rodacki M, Svoren B, Butty V, et al. Altered natural killer cells in type 1 diabetic patients. Diabetes. 2007; 56: 177-85.
-
(2007)
Diabetes
, vol.56
, pp. 177-185
-
-
Rodacki, M.1
Svoren, B.2
Butty, V.3
-
100
-
-
0021802879
-
Predominance of lymphocytes-t in pancreatic-islets and spleen of pre-diabetic non-obese diabetic (NOD) mice - a longitudinal-study
-
Miyazaki A, Hanafusa T, Yamada K, et al. Predominance of lymphocytes-t in pancreatic-islets and spleen of pre-diabetic non-obese diabetic (NOD) mice - a longitudinal-study. Clin Exp Immunol. 1985; 60: 622-30.
-
(1985)
Clin Exp Immunol
, vol.60
, pp. 622-630
-
-
Miyazaki, A.1
Hanafusa, T.2
Yamada, K.3
-
101
-
-
77951922471
-
Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice
-
Brauner H, Elemans M, Lemos S, et al. Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice. J Immunol. 2010; 184: 2272-80.
-
(2010)
J Immunol
, vol.184
, pp. 2272-2280
-
-
Brauner, H.1
Elemans, M.2
Lemos, S.3
-
102
-
-
75649104301
-
The activating receptor NKp46 is essential for the development of type 1 diabetes
-
Gur C, Porgador A, Elboim M, et al. The activating receptor NKp46 is essential for the development of type 1 diabetes. Nat Immunol. 2010; 11: 121-37.
-
(2010)
Nat Immunol
, vol.11
, pp. 121-137
-
-
Gur, C.1
Porgador, A.2
Elboim, M.3
-
104
-
-
0021217853
-
Deficiency of monoclonal-antibody (leu7) defined nk-cells in newly diagnosed insulin-dependent diabetes-mellitus
-
Chandy KG, Charles MA, Buckingham B, et al. Deficiency of monoclonal-antibody (leu7) defined nk-cells in newly diagnosed insulin-dependent diabetes-mellitus. Immunol Lett. 1984; 8: 89-91.
-
(1984)
Immunol Lett
, vol.8
, pp. 89-91
-
-
Chandy, K.G.1
Charles, M.A.2
Buckingham, B.3
-
105
-
-
79952140360
-
Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells
-
Qin HJ, Wang ZD, Du WT, et al. Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells. Proc Natl Acad Sci USA. 2011; 108: 2016-21.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 2016-2021
-
-
Qin, H.J.1
Wang, Z.D.2
Du, W.T.3
-
106
-
-
58149299735
-
Analysis of islet inflammation in human type 1 diabetes
-
Willcox A, Richardson SJ, Bone AJ, et al. Analysis of islet inflammation in human type 1 diabetes. Clin Exp Immunol. 2009; 155: 173-81.
-
(2009)
Clin Exp Immunol
, vol.155
, pp. 173-181
-
-
Willcox, A.1
Richardson, S.J.2
Bone, A.J.3
-
107
-
-
0036378060
-
Dendritic cells, chemokine receptors and autoimmune inflammatory diseases
-
Cravens PD, Lipsky PE. Dendritic cells, chemokine receptors and autoimmune inflammatory diseases. Immunol Cell Biol. 2002; 80: 497-505.
-
(2002)
Immunol Cell Biol
, vol.80
, pp. 497-505
-
-
Cravens, P.D.1
Lipsky, P.E.2
-
108
-
-
84880924243
-
The role of dendritic cells in autoimmunity
-
Ganguly D, Haak S, Sisirak V, et al. The role of dendritic cells in autoimmunity. Nat Rev Immunol. 2013; 13: 566-77.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 566-577
-
-
Ganguly, D.1
Haak, S.2
Sisirak, V.3
-
109
-
-
39049088951
-
Dendritic cells and cytokines in human inflammatory and autoimmune diseases
-
Blanco P, Palucka AK, Pascual V, et al. Dendritic cells and cytokines in human inflammatory and autoimmune diseases. Cytokine Growth F R. 2008; 19: 41-52.
-
(2008)
Cytokine Growth F R
, vol.19
, pp. 41-52
-
-
Blanco, P.1
Palucka, A.K.2
Pascual, V.3
-
110
-
-
0035879111
-
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase
-
Grohmann U, Fallarino FFAU, Bianchi R, et al. IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2, 3-dioxygenase. J Immunol. 2001; 167: 708-14.
-
(2001)
J Immunol
, vol.167
, pp. 708-714
-
-
Grohmann, U.1
Fallarino, F.F.A.U.2
Bianchi, R.3
-
111
-
-
27644491043
-
Altered phenotype and function of dendritic cells in children with type 1 diabetes
-
Angelini F, Del Duca EFAU, Piccinini S, et al. Altered phenotype and function of dendritic cells in children with type 1 diabetes. Clin Exp Immunol. 2005; 142: 341-6.
-
(2005)
Clin Exp Immunol
, vol.142
, pp. 341-346
-
-
Angelini, F.1
Del Duca, E.F.A.U.2
Piccinini, S.3
-
112
-
-
49149097651
-
Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes
-
Mollah ZU, Pai SFAU, Moore C, et al. Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes. J Immunol. 2008; 180: 3166-75.
-
(2008)
J Immunol
, vol.180
, pp. 3166-3175
-
-
Mollah, Z.U.1
Pai, S.F.A.U.2
Moore, C.3
-
113
-
-
0037815119
-
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice
-
Grohmann U, Fallarino FFAU, Bianchi R, et al. A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice. J Exp Med. 2003; 198: 153-60.
-
(2003)
J Exp Med
, vol.198
, pp. 153-160
-
-
Grohmann, U.1
Fallarino, F.F.A.U.2
Bianchi, R.3
-
114
-
-
80052352967
-
Modulation of regulatory T cell-Th17 balance by plasmacytoid dendritic cells
-
Gautreau L, Chabannes D, Heslan M, et al. Modulation of regulatory T cell-Th17 balance by plasmacytoid dendritic cells. J Leukocyte Biol. 2011; 90: 521-7.
-
(2011)
J Leukocyte Biol
, vol.90
, pp. 521-527
-
-
Gautreau, L.1
Chabannes, D.2
Heslan, M.3
-
115
-
-
44449109208
-
Differential control of T regulatory cell proliferation and suppressive activity by mature plasmacytoid versus conventional spleen dendritic cells
-
Ouabed A, Hubert FX, Chabannes D, et al. Differential control of T regulatory cell proliferation and suppressive activity by mature plasmacytoid versus conventional spleen dendritic cells. J Immunol. 2008; 180: 5862-70.
-
(2008)
J Immunol
, vol.180
, pp. 5862-5870
-
-
Ouabed, A.1
Hubert, F.X.2
Chabannes, D.3
-
116
-
-
80054805349
-
Innate immunity in type 1 diabetes
-
Diana J, Gahzarian L, Simoni Y, et al. Innate immunity in type 1 diabetes. Discov Med. 2011; 11: 513-20.
-
(2011)
Discov Med
, vol.11
, pp. 513-520
-
-
Diana, J.1
Gahzarian, L.2
Simoni, Y.3
-
117
-
-
39449126502
-
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
-
Tang Q, Bluestone JA. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol. 2008; 9: 239-44.
-
(2008)
Nat Immunol
, vol.9
, pp. 239-244
-
-
Tang, Q.1
Bluestone, J.A.2
-
118
-
-
78651345190
-
Altered toll-like receptor signaling pathways in human type 1 diabetes
-
Meyers AJ, Shah RR, Gottlieb PA, et al. Altered toll-like receptor signaling pathways in human type 1 diabetes. J Mol Med. 2010; 88: 1221-31.
-
(2010)
J Mol Med
, vol.88
, pp. 1221-1231
-
-
Meyers, A.J.1
Shah, R.R.2
Gottlieb, P.A.3
-
119
-
-
59249097729
-
APC dysfunction is correlated with defective suppression of T cell proliferation in human type 1 diabetes
-
Jin Y, Chen XQ, Podolsky R, et al. APC dysfunction is correlated with defective suppression of T cell proliferation in human type 1 diabetes. Clin Immunol. 2009; 130: 272-9.
-
(2009)
Clin Immunol
, vol.130
, pp. 272-279
-
-
Jin, Y.1
Chen, X.Q.2
Podolsky, R.3
-
121
-
-
84883071615
-
The systemic immune network in recent onset type 1 diabetes: central role of interleukin-1 receptor antagonist (DIATOR Trial)
-
Kolb H, Luckemeyer K, Heise T, et al. The systemic immune network in recent onset type 1 diabetes: central role of interleukin-1 receptor antagonist (DIATOR Trial). PLoS ONE. 2013; 8: e72440.
-
(2013)
PLoS ONE
, vol.8
-
-
Kolb, H.1
Luckemeyer, K.2
Heise, T.3
-
122
-
-
27644470987
-
The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation
-
Lee LF, Xu B, Michie SA, et al. The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation. Proc Natl Acad Sci USA. 2005; 102: 15995-6000.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15995-16000
-
-
Lee, L.F.1
Xu, B.2
Michie, S.A.3
-
123
-
-
73949129793
-
Interleukin-17-producing gamma delta plus T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-beta
-
Han G, Wang R, Chen G, et al. Interleukin-17-producing gamma delta plus T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-beta. Immunology. 2010; 129: 197-206.
-
(2010)
Immunology
, vol.129
, pp. 197-206
-
-
Han, G.1
Wang, R.2
Chen, G.3
-
124
-
-
84870424721
-
Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality?
-
Simoni Y, Diana J, Ghazarian L, et al. Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality? Clin Exp Immunol. 2013; 171: 8-19.
-
(2013)
Clin Exp Immunol
, vol.171
, pp. 8-19
-
-
Simoni, Y.1
Diana, J.2
Ghazarian, L.3
-
125
-
-
79955738789
-
Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay
-
Diana J, Brezar V, Beaudoin L, et al. Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay. J Exp Med. 2011; 208: 729-45.
-
(2011)
J Exp Med
, vol.208
, pp. 729-745
-
-
Diana, J.1
Brezar, V.2
Beaudoin, L.3
-
126
-
-
80052623696
-
Structure-guided design of an invariant natural killer T cell agonist for optimum protection from type 1 diabetes in non-obese diabetic mice
-
Blumenfeld HJ, Tohn R, Haeryfar SMM, et al. Structure-guided design of an invariant natural killer T cell agonist for optimum protection from type 1 diabetes in non-obese diabetic mice. Clin Exp Immunol. 2011; 166: 121-33.
-
(2011)
Clin Exp Immunol
, vol.166
, pp. 121-133
-
-
Blumenfeld, H.J.1
Tohn, R.2
Haeryfar, S.M.M.3
-
127
-
-
84860539468
-
Toll-like receptor 4 on islet beta cells senses expression changes in high-mobility group box 1 and contributes to the initiation of type 1 diabetes
-
Li M, Song LJ, Gao XD, et al. Toll-like receptor 4 on islet beta cells senses expression changes in high-mobility group box 1 and contributes to the initiation of type 1 diabetes. Exp Mol Med. 2012; 44: 260-7.
-
(2012)
Exp Mol Med
, vol.44
, pp. 260-267
-
-
Li, M.1
Song, L.J.2
Gao, X.D.3
-
128
-
-
84875211293
-
Mechanistic basis of immunotherapies for type 1 diabetes mellitus
-
Chen WH, Xie AN, Chan L. Mechanistic basis of immunotherapies for type 1 diabetes mellitus. Transl Res. 2013; 161: 217-29.
-
(2013)
Transl Res
, vol.161
, pp. 217-229
-
-
Chen, W.H.1
Xie, A.N.2
Chan, L.3
-
129
-
-
84856436834
-
Type 1 diabetes mellitus in 2011 heterogeneity of T1DM raises questions for therapy
-
Pozzilli P. Type 1 diabetes mellitus in 2011 heterogeneity of T1DM raises questions for therapy. Nat Rev Endocrinol. 2012; 8: 78-80.
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 78-80
-
-
Pozzilli, P.1
-
130
-
-
80053611194
-
Dendritic cells expressing BTLA induces CD8(+) T cell tolerance and attenuates the severity of diabetes
-
Li S, Zhang M, Xiang F, et al. Dendritic cells expressing BTLA induces CD8(+) T cell tolerance and attenuates the severity of diabetes. Vaccine. 2011; 29: 7747-51.
-
(2011)
Vaccine
, vol.29
, pp. 7747-7751
-
-
Li, S.1
Zhang, M.2
Xiang, F.3
-
131
-
-
84872853977
-
Immune therapy in type 1 diabetes mellitus
-
Lernmark A, Larsson HE. Immune therapy in type 1 diabetes mellitus. Nat Rev Endocrinol. 2013; 9: 92-103.
-
(2013)
Nat Rev Endocrinol
, vol.9
, pp. 92-103
-
-
Lernmark, A.1
Larsson, H.E.2
-
132
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
Herold KC, Hagopian W, Auger JA, et al. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. New Engl J Med. 2002; 346: 1692-8.
-
(2002)
New Engl J Med
, vol.346
, pp. 1692-1698
-
-
Herold, K.C.1
Hagopian, W.2
Auger, J.A.3
-
133
-
-
79551655241
-
Hematopoietic stem cell transplantation for the treatment of autoimmunity in type 1 diabetes
-
LoCascio SA, Spinelli J, Kurtz J. Hematopoietic stem cell transplantation for the treatment of autoimmunity in type 1 diabetes. Curr Stem Cell Res Ther. 2011; 6: 29-37.
-
(2011)
Curr Stem Cell Res Ther
, vol.6
, pp. 29-37
-
-
LoCascio, S.A.1
Spinelli, J.2
Kurtz, J.3
-
134
-
-
84866631736
-
Immune regulatory properties of allogeneic adipose-derived mesenchymal stem cells in the treatment of experimental autoimmune diabetes
-
Bassi EJ, Moraes-Vieira P, Moreira-Sa C, et al. Immune regulatory properties of allogeneic adipose-derived mesenchymal stem cells in the treatment of experimental autoimmune diabetes. Diabetes. 2012; 61: 2534-45.
-
(2012)
Diabetes
, vol.61
, pp. 2534-2545
-
-
Bassi, E.J.1
Moraes-Vieira, P.2
Moreira-Sa, C.3
-
135
-
-
84870839254
-
Harnessing the immunomodulatory and tissue repair properties of mesenchymal stem cells to restore beta cell function
-
Davis NE, Hamilton D, Fontaine MJ. Harnessing the immunomodulatory and tissue repair properties of mesenchymal stem cells to restore beta cell function. Curr Diabetes Rep. 2012; 12: 612-22.
-
(2012)
Curr Diabetes Rep
, vol.12
, pp. 612-622
-
-
Davis, N.E.1
Hamilton, D.2
Fontaine, M.J.3
-
136
-
-
79960996764
-
GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes
-
Soltani N, Qiu H, Aleksic M, et al. GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes. Proc Natl Acad Sci USA. 2011; 108: 11692-7.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11692-11697
-
-
Soltani, N.1
Qiu, H.2
Aleksic, M.3
-
137
-
-
84861905980
-
The novel therapeutic effect of phosphoinositide 3-kinase-gamma inhibitor AS605240 in autoimmune diabetes
-
Azzi J, Moore RF, Elyaman W, et al. The novel therapeutic effect of phosphoinositide 3-kinase-gamma inhibitor AS605240 in autoimmune diabetes. Diabetes. 2012; 61: 1509-18.
-
(2012)
Diabetes
, vol.61
, pp. 1509-1518
-
-
Azzi, J.1
Moore, R.F.2
Elyaman, W.3
|