IL-2 promotes the function of memory-like autoregulatory CD8+ T cells but suppresses their development via FoxP3+ Treg cells

European Journal of Immunology

Volumn 43, Issue 2, 2013, Pages 394-403

  Shameli, Afshin ^a   Yamanouchi, Jun ^a   Tsai, Sue ^a   Yang, Yang ^a,b   Clemente Casares, Xavier ^a   Moore, Anna ^c   Serra, Pau ^d   Santamaria, Pere ^a,d  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HOSPITAL CLÍNIC   (Spain)

Author keywords

Autoregulatory T cell memory; CD122; FoxP3+CD25+ Treg cells; IL 2; Type 1 diabetes

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; TRANSCRIPTION FACTOR FOXP3;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; FEMALE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MEMORY T LYMPHOCYTE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DIABETES MELLITUS, TYPE 1; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HOMEOSTASIS; IMMUNOLOGIC MEMORY; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES, REGULATORY;

EID: 84873749432     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242845     Document Type: Article

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