-
1
-
-
33645821472
-
The honeymoon phase' in children with type 1 diabetes mellitus: frequency, duration, and influential factors
-
doi:10.1111/j.1399-543X.2006.00155.x
-
Abdul-Rasoul, M., Habib, H., and Al-Khouly, M. (2006). The honeymoon phase' in children with type 1 diabetes mellitus: frequency, duration, and influential factors. Pediatr. Diabetes 7, 101-107. doi:10.1111/j.1399-543X.2006.00155.x
-
(2006)
Pediatr. Diabetes
, vol.7
, pp. 101-107
-
-
Abdul-Rasoul, M.1
Habib, H.2
Al-Khouly, M.3
-
2
-
-
34249012115
-
Autoimmunity and beta cell regeneration in mouse and human type 1 diabetes: the peace is not enough
-
doi:10.1196/annals.1394.006
-
Ablamunits, V., Sherry, N. A., Kushner, J. A., and Herold, K. C. (2007). Autoimmunity and beta cell regeneration in mouse and human type 1 diabetes: the peace is not enough. Ann. N. Y. Acad. Sci. 1103, 19-32. doi:10.1196/annals.1394.006
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1103
, pp. 19-32
-
-
Ablamunits, V.1
Sherry, N.A.2
Kushner, J.A.3
Herold, K.C.4
-
3
-
-
32244445416
-
Natural regulatory T cells control the development of atherosclerosis in mice
-
doi:10.1038/nm1343
-
Ait-Oufella, H., Salomon, B. L., Potteaux, S., Robertson, A. K., Gourdy, P., Zoll, J., et al. (2006). Natural regulatory T cells control the development of atherosclerosis in mice. Nat. Med. 12, 178-180. doi:10.1038/nm1343
-
(2006)
Nat. Med.
, vol.12
, pp. 178-180
-
-
Ait-Oufella, H.1
Salomon, B.L.2
Potteaux, S.3
Robertson, A.K.4
Gourdy, P.5
Zoll, J.6
-
4
-
-
58149348476
-
Beta-cell mass and type 1 diabetes: going, going, gone?
-
doi:10.2337/db07-1817
-
Akirav, E., Kushner, J. A., and Herold, K. C. (2008). Beta-cell mass and type 1 diabetes: going, going, gone? Diabetes 57, 2883-2888. doi:10.2337/db07-1817
-
(2008)
Diabetes
, vol.57
, pp. 2883-2888
-
-
Akirav, E.1
Kushner, J.A.2
Herold, K.C.3
-
5
-
-
17644361955
-
The NOD mouse: a model of immune dysregulation
-
doi:10.1146/annurev.immunol.23.021704.115643
-
Anderson, M. S., and Bluestone, J. A. (2005). The NOD mouse: a model of immune dysregulation. Annu. Rev. Immunol. 23, 447-485. doi:10.1146/annurev.immunol.23.021704.115643
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 447-485
-
-
Anderson, M.S.1
Bluestone, J.A.2
-
6
-
-
20044387026
-
IKK-beta links inflammation to obesity-induced insulin resistance
-
doi:10.1038/nm1185
-
Arkan, M. C., Hevener, A. L., Greten, F. R., Maeda, A., Li, Z. W., Long, J. M., et al. (2005). IKK-beta links inflammation to obesity-induced insulin resistance. Nat. Med. 11, 191-198. doi:10.1038/nm1185
-
(2005)
Nat. Med.
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, A.4
Li, Z.W.5
Long, J.M.6
-
7
-
-
0033001488
-
The NOD mouse model of type 1 diabetes: as good as it gets?
-
doi:10.1038/9442
-
Atkinson, M. A., and Leiter, E. H. (1999). The NOD mouse model of type 1 diabetes: as good as it gets? Nat. Med. 5, 601-604. doi:10.1038/9442
-
(1999)
Nat Med.
, vol.5
, pp. 601-604
-
-
Atkinson, M.A.1
Leiter, E.H.2
-
8
-
-
0035061536
-
Tolerance to islet autoantigens in type 1 diabetes
-
doi:10.1146/annurev.immunol.19.1.131
-
Bach, J. F., and Chatenoud, L. (2001). Tolerance to islet autoantigens in type 1 diabetes. Annu. Rev. Immunol. 19, 131-161. doi:10.1146/annurev.immunol.19.1.131
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 131-161
-
-
Bach, J.F.1
Chatenoud, L.2
-
9
-
-
34447617193
-
Induction of the chemokine interferon-gamma-inducible protein-10 in human pancreatic islets during enterovirus infection
-
doi:10.1007/s00125-006-0429-7
-
Berg, A. K., Korsgren, O., and Frisk, G. (2006). Induction of the chemokine interferon-gamma-inducible protein-10 in human pancreatic islets during enterovirus infection. Diabetologia 49, 2697-2703. doi:10.1007/s00125-006-0429-7
-
(2006)
Diabetologia
, vol.49
, pp. 2697-2703
-
-
Berg, A.K.1
Korsgren, O.2
Frisk, G.3
-
10
-
-
0037763758
-
Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha
-
doi:10.1530/eje.0.1480535
-
Bruun, J. M., Verdich, C., Toubro, S., Astrup, A., and Richelsen, B. (2003). Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha. Effect of weight loss in obese men. Eur. J. Endocrinol. 148, 535-542. doi:10.1530/eje.0.1480535
-
(2003)
Effect of weight loss in obese men. Eur. J. Endocrinol.
, vol.148
, pp. 535-542
-
-
Bruun, J.M.1
Verdich, C.2
Toubro, S.3
Astrup, A.4
Richelsen, B.5
-
13
-
-
0027958044
-
3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice
-
doi:10.1073/pnas.91.1.123
-
3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc. Natl. Acad. Sci. U.S.A. 91, 123-127. doi:10.1073/pnas.91.1.123
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 123-127
-
-
Chatenoud, L.1
Thervet, E.2
Primo, J.3
Bach, J.F.4
-
14
-
-
74049161267
-
Influence of microbial environment on autoimmunity
-
doi:10.1038/ni.1801
-
Chervonsky, A. V. (2010). Influence of microbial environment on autoimmunity. Nat. Immunol. 11, 28-35. doi:10.1038/ni.1801
-
(2010)
Nat. Immunol.
, vol.11
, pp. 28-35
-
-
Chervonsky, A.V.1
-
16
-
-
77958099053
-
Pancreatic beta-cell neogenesis by direct conversion from mature alpha-cells
-
doi:10.1002/stem.482
-
Chung, C. H., Hao, E., Piran, R., Keinan, E., and Levine, F. (2010). Pancreatic beta-cell neogenesis by direct conversion from mature alpha-cells. Stem Cells 28, 1630 -1638. doi:10.1002/stem.482
-
(2010)
Stem Cells
, vol.28
-
-
Chung, C.H.1
Hao, E.2
Piran, R.3
Keinan, E.4
Levine, F.5
-
17
-
-
84862986986
-
PPAR-gamma is a major driver of the accumulation and phenotype of adipose tissue Treg cells
-
doi:10.1038/nature11132
-
Cipolletta, D., Feuerer, M., Li, A., Kamei, N., Lee, J., Shoelson, S. E., et al. (2012). PPAR-gamma is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature 486, 549-553. doi:10.1038/nature11132
-
(2012)
Nature
, vol.486
, pp. 549-553
-
-
Cipolletta, D.1
Feuerer, M.2
Li, A.3
Kamei, N.4
Lee, J.5
Shoelson, S.E.6
-
18
-
-
36348967350
-
Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions
-
doi:10.1371/journal.pone.0000779
-
de Boer, O. J., Van Der Meer, J. J., Teeling, P., Van Der Loos, C. M., and Van Der Wal, A. C. (2007). Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions. PLoS ONE 2:e779. doi:10.1371/journal.pone.0000779
-
(2007)
PLoS ONE
, vol.2
-
-
de Boer, O.J.1
Van Der Meer, J.J.2
Teeling, P.3
Van Der Loos, C.M.4
Van Der Wal, A.C.5
-
19
-
-
84864080545
-
The immunogenetics of immune dysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
-
doi:10.1136/jmedgenet-2012-100759
-
d'Hennezel, E., Bin Dhuban, K., Torgerson, T., and Piccirillo, C. A. (2012). The immunogenetics of immune dysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. J. Med. Genet. 49, 291-302. doi:10.1136/jmedgenet-2012-100759
-
(2012)
J. Med. Genet.
, vol.49
, pp. 291-302
-
-
d'Hennezel, E.1
Bin Dhuban, K.2
Torgerson, T.3
Piccirillo, C.A.4
-
20
-
-
0041828484
-
Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes
-
doi:10.1007/s00109-003-0450-y
-
Donath, M. Y., Storling, J., Maedler, K., and Mandrup-Poulsen, T. (2003). Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes. J. Mol. Med. (Berl.) 81, 455-470. doi:10.1007/s00109-003-0450-y
-
(2003)
J. Mol. Med. (Berl.)
, vol.81
, pp. 455-470
-
-
Donath, M.Y.1
Storling, J.2
Maedler, K.3
Mandrup-Poulsen, T.4
-
21
-
-
2342510386
-
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
-
doi:10.1038/nature02520
-
Dor, Y., Brown, J., Martinez, O. I., and Melton, D. A. (2004). Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429, 41-46. doi:10.1038/nature02520
-
(2004)
Nature
, vol.429
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
22
-
-
80755168875
-
Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy
-
doi:10.2337/db11-0358
-
Eller, K., Kirsch, A., Wolf, A. M., Sopper, S., Tagwerker, A., Stanzl, U., et al. (2011). Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy. Diabetes 60, 2954-2962. doi:10.2337/db11-0358
-
(2011)
Diabetes
, vol.60
, pp. 2954-2962
-
-
Eller, K.1
Kirsch, A.2
Wolf, A.M.3
Sopper, S.4
Tagwerker, A.5
Stanzl, U.6
-
23
-
-
0030960835
-
Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets
-
doi:10.1210/en.138.4.1750
-
Fernandes, A., King, L. C., Guz, Y., Stein, R., Wright, C. V., and Teitelman, G. (1997). Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets. Endocrinology 138, 1750-1762. doi:10.1210/en.138.4.1750
-
(1997)
Endocrinology
, vol.138
, pp. 1750-1762
-
-
Fernandes, A.1
King, L.C.2
Guz, Y.3
Stein, R.4
Wright, C.V.5
Teitelman, G.6
-
24
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
doi:10.1038/nm.2002
-
Feuerer, M., Herrero, L., Cipolletta, D., Naaz, A., Wong, J., Nayer, A., et al. (2009). Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat. Med. 15, 930-939. doi:10.1038/nm.2002
-
(2009)
Nat. Med.
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
-
25
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
doi:10.1038/ni1263
-
Fontenot, J. D., Rasmussen, J. P., Gavin, M. A., and Rudensky, A. Y. (2005). A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6, 1142-1151. doi:10.1038/ni1263
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
26
-
-
33645454310
-
Leukocyte recruitment and vascular injury in diabetic nephropathy
-
doi:10.1681/ASN.2005080859
-
Galkina, E., and Ley, K. (2006). Leukocyte recruitment and vascular injury in diabetic nephropathy. J. Am. Soc. Nephrol. 17, 368-377. doi:10.1681/ASN.2005080859
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 368-377
-
-
Galkina, E.1
Ley, K.2
-
27
-
-
77956257716
-
IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
-
doi:10.1084/jem.20100209
-
Grinberg-Bleyer, Y., Baeyens, A., You, S., Elhage, R., Fourcade, G., Gregoire, S., et al. (2010). IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells. J. Exp. Med. 207, 1871-1878. doi:10.1084/jem.20100209
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1871-1878
-
-
Grinberg-Bleyer, Y.1
Baeyens, A.2
You, S.3
Elhage, R.4
Fourcade, G.5
Gregoire, S.6
-
28
-
-
0034748027
-
Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes
-
doi:10.1210/en.142.11.4956
-
Guz, Y., Nasir, I., and Teitelman, G. (2001). Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes. Endocrinology 142, 4956-4968. doi:10.1210/en.142.11.4956
-
(2001)
Endocrinology
, vol.142
, pp. 4956-4968
-
-
Guz, Y.1
Nasir, I.2
Teitelman, G.3
-
29
-
-
79955545927
-
Transcriptional regulation of Foxp3 in regulatory T cells
-
doi:10.1016/j.imbio.2010.11.002
-
Haiqi, H., Yong, Z., and Yi, L. (2011). Transcriptional regulation of Foxp3 in regulatory T cells. Immunobiology 216, 678-685. doi:10.1016/j.imbio.2010.11.002
-
(2011)
Immunobiology
, vol.216
, pp. 678-685
-
-
Haiqi, H.1
Yong, Z.2
Yi, L.3
-
32
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
doi:10.1126/science.1079490
-
Hori, S., Nomura, T., and Sakaguchi, S. (2003). Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061. doi:10.1126/science.1079490
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
33
-
-
0026542241
-
Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus
-
doi:10.1172/JCI115573
-
Kaufman, D. L., Erlander, M. G., Clare-Salzler, M., Atkinson, M. A., Maclaren, N. K., and Tobin, A. J. (1992). Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus. J. Clin. Invest. 89, 283-292. doi:10.1172/JCI115573
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 283-292
-
-
Kaufman, D.L.1
Erlander, M.G.2
Clare-Salzler, M.3
Atkinson, M.A.4
Maclaren, N.K.5
Tobin, A.J.6
-
35
-
-
77951433369
-
Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis
-
doi:10.1161/ATVBAHA.109.202671
-
Klingenberg, R., Lebens, M., Hermansson, A., Fredrikson, G. N., Strodthoff, D., Rudling, M., et al. (2010). Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 30, 946-952. doi:10.1161/ATVBAHA.109.202671
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 946-952
-
-
Klingenberg, R.1
Lebens, M.2
Hermansson, A.3
Fredrikson, G.N.4
Strodthoff, D.5
Rudling, M.6
-
36
-
-
31444451575
-
Environmental triggers and determinants of type 1 diabetes
-
doi:10.2337/diabetes.54.suppl_2.S125
-
Knip, M., Veijola, R., Virtanen, S. M., Hyoty, H., Vaarala, O., and Akerblom, H. K. (2005). Environmental triggers and determinants of type 1 diabetes. Diabetes 54 (Suppl. 2), S125-S136. doi:10.2337/diabetes.54.suppl_2.S125
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Knip, M.1
Veijola, R.2
Virtanen, S.M.3
Hyoty, H.4
Vaarala, O.5
Akerblom, H.K.6
-
37
-
-
84856585744
-
3+ regulatory T cells in islets of nonobese diabetic mice
-
doi:10.4049/jimmunol.1101303
-
3+ regulatory T cells in islets of nonobese diabetic mice. J. Immunol. 188, 1064-1074. doi:10.4049/jimmunol.1101303
-
(2012)
J. Immunol.
, vol.188
, pp. 1064-1074
-
-
Kornete, M.1
Sgouroudis, E.2
Piccirillo, C.A.3
-
38
-
-
33845316086
-
Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP
-
doi:10.1172/JCI29602
-
Krishnamurthy, B., Dudek, N. L., Mckenzie, M. D., Purcell, A. W., Brooks, A. G., Gellert, S., et al. (2006). Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP. J. Clin. Invest. 116, 3258-3265. doi:10.1172/JCI29602
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 3258-3265
-
-
Krishnamurthy, B.1
Dudek, N.L.2
Mckenzie, M.D.3
Purcell, A.W.4
Brooks, A.G.5
Gellert, S.6
-
40
-
-
55249110198
-
GAD treatment and insulin secretion in recent-onset type 1 diabetes
-
doi:10.1056/NEJMoa0804328
-
Ludvigsson, J., Faresjo, M., Hjorth, M., Axelsson, S., Cheramy, M., Pihl, M., et al. (2008). GAD treatment and insulin secretion in recent-onset type 1 diabetes. N. Engl. J. Med. 359, 1909-1920. doi:10.1056/NEJMoa0804328
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1909-1920
-
-
Ludvigsson, J.1
Faresjo, M.2
Hjorth, M.3
Axelsson, S.4
Cheramy, M.5
Pihl, M.6
-
41
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
doi:10.1172/JCI29881
-
Lumeng, C. N., Bodzin, J. L., and Saltiel, A. R. (2007). Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest. 117, 175-184. doi:10.1172/JCI29881
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
42
-
-
20844446146
-
3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice
-
doi:10.1097/01.TP.0000161223.54452.A2
-
3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice. Transplantation 79, 1091-1096. doi:10.1097/01.TP.0000161223.54452.A2
-
(2005)
Transplantation
, vol.79
, pp. 1091-1096
-
-
Luo, X.1
Yang, H.2
Kim, I.S.3
Saint-Hilaire, F.4
Thomas, D.A.5
De, B.P.6
-
43
-
-
0034075807
-
Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping
-
doi:10.1101/gr.10.4.446
-
Lyons, P. A., Armitage, N., Argentina, F., Denny, P., Hill, N. J., Lord, C. J., et al. (2000). Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping. Genome Res. 10, 446-453. doi:10.1101/gr.10.4.446
-
(2000)
Genome Res.
, vol.10
, pp. 446-453
-
-
Lyons, P.A.1
Armitage, N.2
Argentina, F.3
Denny, P.4
Hill, N.J.5
Lord, C.J.6
-
44
-
-
0041915628
-
Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockout mice
-
doi:10.1161/01.CIR.0000089083.61317.A1
-
Mallat, Z., Gojova, A., Brun, V., Esposito, B., Fournier, N., Cottrez, F., et al. (2003). Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockout mice. Circulation 108, 1232-1237. doi:10.1161/01.CIR.0000089083.61317.A1
-
(2003)
Circulation
, vol.108
, pp. 1232-1237
-
-
Mallat, Z.1
Gojova, A.2
Brun, V.3
Esposito, B.4
Fournier, N.5
Cottrez, F.6
-
45
-
-
83655165390
-
The influence of the microbiota on type-1 diabetes: on the threshold of a leap forward in our understanding
-
doi:10.1111/j.1600-065X.2011.01084.x
-
Mathis, D., and Benoist, C. (2012). The influence of the microbiota on type-1 diabetes: on the threshold of a leap forward in our understanding. Immunol. Rev. 245, 239-249. doi:10.1111/j.1600-065X.2011.01084.x
-
(2012)
Immunol. Rev.
, vol.245
, pp. 239-249
-
-
Mathis, D.1
Benoist, C.2
-
46
-
-
79955028001
-
Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes
-
doi:10.4049/jimmunol.1003099
-
McClymont, S. A., Putnam, A. L., Lee, M. R., Esensten, J. H., Liu, W., Hulme, M. A., et al. (2011). Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. J. Immunol. 186, 3918-3926. doi:10.4049/jimmunol.1003099
-
(2011)
J. Immunol.
, vol.186
, pp. 3918-3926
-
-
McClymont, S.A.1
Putnam, A.L.2
Lee, M.R.3
Esensten, J.H.4
Liu, W.5
Hulme, M.A.6
-
47
-
-
84862807705
-
Aberrant recruitment and activation of T cells in diabetic nephropathy
-
doi:10.1159/000334928
-
Moon, J. Y., Jeong, K. H., Lee, T. W., Ihm, C. G., Lim, S. J., and Lee, S. H. (2012). Aberrant recruitment and activation of T cells in diabetic nephropathy. Am. J. Nephrol. 35, 164-174. doi:10.1159/000334928
-
(2012)
Am. J. Nephrol.
, vol.35
, pp. 164-174
-
-
Moon, J.Y.1
Jeong, K.H.2
Lee, T.W.3
Ihm, C.G.4
Lim, S.J.5
Lee, S.H.6
-
48
-
-
0032934914
-
Partial remission phase of diabetes in children younger than age 10 years
-
doi:10.1136/adc.80.4.367
-
Muhammad, B. J., Swift, P. G. F., Raymond, N. T., and Botha, J. L. (1999). Partial remission phase of diabetes in children younger than age 10 years. Arch. Dis. Child. 80, 367-369. doi:10.1136/adc.80.4.367
-
(1999)
Arch. Dis. Child.
, vol.80
, pp. 367-369
-
-
Muhammad, B.J.1
Swift, P.G.F.2
Raymond, N.T.3
Botha, J.L.4
-
49
-
-
34848887156
-
Recovery from diabetes in mice by beta cell regeneration
-
doi:10.1172/JCI32959
-
Nir, T., Melton, D. A., and Dor, Y. (2007). Recovery from diabetes in mice by beta cell regeneration. J. Clin. Invest. 117, 2553-2561. doi:10.1172/JCI32959
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2553-2561
-
-
Nir, T.1
Melton, D.A.2
Dor, Y.3
-
50
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
doi:10.1038/nm.1964
-
Nishimura, S., Manabe, I., Nagasaki, M., Eto, K., Yamashita, H., Ohsugi, M., et al. (2009). CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat. Med. 15, 914-920. doi:10.1038/nm.1964
-
(2009)
Nat. Med.
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Eto, K.4
Yamashita, H.5
Ohsugi, M.6
-
51
-
-
72249122333
-
Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1
-
doi:10.2337/dc09-0934
-
Orban, T., Sosenko, J. M., Cuthbertson, D., Krischer, J. P., Skyler, J. S., Jackson, R., et al. (2009). Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1. Diabetes Care 32, 2269-2274. doi:10.2337/dc09-0934
-
(2009)
Diabetes Care
, vol.32
, pp. 2269-2274
-
-
Orban, T.1
Sosenko, J.M.2
Cuthbertson, D.3
Krischer, J.P.4
Skyler, J.S.5
Jackson, R.6
-
52
-
-
80051931752
-
3 therapy promotes tolerance by selectively depleting pathogenic cells while preserving regulatory T cells
-
doi:10.4049/jimmunol.1100713
-
3 therapy promotes tolerance by selectively depleting pathogenic cells while preserving regulatory T cells. J. Immunol. 187, 2015-2022. doi:10.4049/jimmunol.1100713
-
(2011)
J. Immunol.
, vol.187
, pp. 2015-2022
-
-
Penaranda, C.1
Tang, Q.2
Bluestone, J.A.3
-
53
-
-
25444510061
-
Control of type 1 autoimmune diabetes by naturally occurring CD4+CD25+ regulatory T lymphocytes in neonatal NOD mice
-
doi:10.1196/annals.1361.048
-
Piccirillo, C. A., Tritt, M., Sgouroudis, E., Albanese, A., Pyzik, M., and Hay, V. (2005). Control of type 1 autoimmune diabetes by naturally occurring CD4+CD25+ regulatory T lymphocytes in neonatal NOD mice. Ann. N. Y. Acad. Sci. 1051, 72-87. doi:10.1196/annals.1361.048
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1051
, pp. 72-87
-
-
Piccirillo, C.A.1
Tritt, M.2
Sgouroudis, E.3
Albanese, A.4
Pyzik, M.5
Hay, V.6
-
54
-
-
0036310118
-
Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue
-
doi:10.2337/diabetes.51.3.686
-
Rooman, I., Lardon, J., and Bouwens, L. (2002). Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue. Diabetes 51, 686-690. doi:10.2337/diabetes.51.3.686
-
(2002)
Diabetes
, vol.51
, pp. 686-690
-
-
Rooman, I.1
Lardon, J.2
Bouwens, L.3
-
55
-
-
0033311156
-
Diabetes-associated autoantibodies in relation to clinical characteristics and natural course in children with newly diagnosed type 1 diabetes
-
doi:10.1210/jc.84.5.1534
-
Sabbah, E., Savola, K., Kulmala, P., Veijola, R., Vahasalo, P., Karjalainen, J., et al. (1999). Diabetes-associated autoantibodies in relation to clinical characteristics and natural course in children with newly diagnosed type 1 diabetes. The Childhood Diabetes in Finland Study Group. J. Clin. Endocrinol. Metab. 84, 1534-1539. doi:10.1210/jc.84.5.1534
-
(1999)
The Childhood Diabetes in Finland Study Group. J. Clin. Endocrinol. Metab.
, vol.84
, pp. 1534-1539
-
-
Sabbah, E.1
Savola, K.2
Kulmala, P.3
Veijola, R.4
Vahasalo, P.5
Karjalainen, J.6
-
56
-
-
73549091444
-
Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance
-
doi:10.1128/MCB.01162-09
-
Sabio, G., Kennedy, N. J., Cavanagh-Kyros, J., Jung, D. Y., Ko, H. J., Ong, H., et al. (2010). Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance. Mol. Cell. Biol. 30, 106-115. doi:10.1128/MCB.01162-09
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 106-115
-
-
Sabio, G.1
Kennedy, N.J.2
Cavanagh-Kyros, J.3
Jung, D.Y.4
Ko, H.J.5
Ong, H.6
-
57
-
-
70349512606
-
Regulatory T cells: how do they suppress immune responses?
-
doi:10.1093/intimm/dxp095
-
Sakaguchi, S., Wing, K., Onishi, Y., Prieto-Martin, P., and Yamaguchi, T. (2009). Regulatory T cells: how do they suppress immune responses? Int. Immunol. 21, 1105-1111. doi:10.1093/intimm/dxp095
-
(2009)
Int. Immunol.
, vol.21
, pp. 1105-1111
-
-
Sakaguchi, S.1
Wing, K.2
Onishi, Y.3
Prieto-Martin, P.4
Yamaguchi, T.5
-
58
-
-
0035059417
-
Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
-
doi:10.1146/annurev.immunol.19.1.225
-
Salomon, B., and Bluestone, J. A. (2001). Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annu. Rev. Immunol. 19, 225-252. doi:10.1146/annurev.immunol.19.1.225
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 225-252
-
-
Salomon, B.1
Bluestone, J.A.2
-
59
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
doi:10.1016/S1074-7613(00)80195-8
-
Salomon, B. T., Lenschow, D. J., Rhee, L., Ashourian, N., Singh, B., Sharpe, A., et al. (2000). B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12, 431-440. doi:10.1016/S1074-7613(00)80195-8
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.T.1
Lenschow, D.J.2
Rhee, L.3
Ashourian, N.4
Singh, B.5
Sharpe, A.6
-
60
-
-
56749178234
-
3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice
-
3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice. J. Immunol. 181, 6283-6292.
-
(2008)
J. Immunol.
, vol.181
, pp. 6283-6292
-
-
Sgouroudis, E.1
Albanese, A.2
Piccirillo, C.A.3
-
61
-
-
69449096138
-
Transcriptional regulation of Foxp3 gene: multiple signal pathways on the road
-
doi:10.1002/med.20152
-
Shen, Z., Chen, L., Hao, F., and Wu, J. (2009). Transcriptional regulation of Foxp3 gene: multiple signal pathways on the road. Med. Res. Rev. 29, 742-766. doi:10.1002/med.20152
-
(2009)
Med. Res. Rev.
, vol.29
, pp. 742-766
-
-
Shen, Z.1
Chen, L.2
Hao, F.3
Wu, J.4
-
62
-
-
33845523340
-
Effects of autoimmunity and immune therapy on beta-cell turnover in type 1 diabetes
-
doi:10.2337/db05-1034
-
Sherry, N. A., Kushner, J. A., Glandt, M., Kitamura, T., Brillantes, A. M., and Herold, K. C. (2006). Effects of autoimmunity and immune therapy on beta-cell turnover in type 1 diabetes. Diabetes 55, 3238-3245. doi:10.2337/db05-1034
-
(2006)
Diabetes
, vol.55
, pp. 3238-3245
-
-
Sherry, N.A.1
Kushner, J.A.2
Glandt, M.3
Kitamura, T.4
Brillantes, A.M.5
Herold, K.C.6
-
63
-
-
65549136983
-
3+ T regulatory cell-mediated suppression
-
doi:10.1016/j.immuni
-
3+ T regulatory cell-mediated suppression. Immunity 30, 636-645. doi:10.1016/j.immuni
-
(2009)
Immunity
, vol.30
, pp. 636-645
-
-
Shevach, E.M.1
-
64
-
-
18144391496
-
Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial - Type 1
-
doi:10.2337/diacare.28.5.1068
-
Skyler, J. S., Krischer, J. P., Wolfsdorf, J., Cowie, C., Palmer, J. P., Greenbaum, C., et al. (2005). Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial - Type 1. Diabetes Care 28, 1068-1076. doi:10.2337/diacare.28.5.1068
-
(2005)
Diabetes Care
, vol.28
, pp. 1068-1076
-
-
Skyler, J.S.1
Krischer, J.P.2
Wolfsdorf, J.3
Cowie, C.4
Palmer, J.P.5
Greenbaum, C.6
-
66
-
-
43049174722
-
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
-
doi:10.1016/j.immuni.2008.03.016
-
Tang, Q., Adams, J. Y., Penaranda, C., Melli, K., Piaggio, E., Sgouroudis, E., et al. (2008). Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity 28, 687-697. doi:10.1016/j.immuni.2008.03.016
-
(2008)
Immunity
, vol.28
, pp. 687-697
-
-
Tang, Q.1
Adams, J.Y.2
Penaranda, C.3
Melli, K.4
Piaggio, E.5
Sgouroudis, E.6
-
67
-
-
77951611220
-
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
-
doi:10.1038/nature08894
-
Thorel, F., Nepote, V., Avril, I., Kohno, K., Desgraz, R., Chera, S., et al. (2010). Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss. Nature 464, 1149-1154. doi:10.1038/nature08894
-
(2010)
Nature
, vol.464
, pp. 1149-1154
-
-
Thorel, F.1
Nepote, V.2
Avril, I.3
Kohno, K.4
Desgraz, R.5
Chera, S.6
-
68
-
-
33645868980
-
Ontogeny of regeneration of beta-cells in the neonatal rat after treatment with streptozotocin
-
doi:10.1210/en.2005-0396
-
Thyssen, S., Arany, E., and Hill, D. J. (2006). Ontogeny of regeneration of beta-cells in the neonatal rat after treatment with streptozotocin. Endocrinology 147, 2346 -2356. doi:10.1210/en.2005-0396
-
(2006)
Endocrinology
, vol.147
-
-
Thyssen, S.1
Arany, E.2
Hill, D.J.3
-
69
-
-
38449090623
-
Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes
-
doi:10.2337/db06-1700
-
Tritt, M., Sgouroudis, E., d'Hennezel, E., Albanese, A., and Piccirizllo, C. A. (2008). Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes. Diabetes 57, 113-123. doi:10.2337/db06-1700
-
(2008)
Diabetes
, vol.57
, pp. 113-123
-
-
Tritt, M.1
Sgouroudis, E.2
d'Hennezel, E.3
Albanese, A.4
Piccirizllo, C.A.5
-
70
-
-
0025748693
-
Role of tumor necrosis factor-alpha and interferon-gamma as growth factors to the human fetal beta-cell
-
doi:10.1210/jcem-73-5-1044
-
Tuch, B. E., Simpson, A. M., and Campbell, I. L. (1991). Role of tumor necrosis factor-alpha and interferon-gamma as growth factors to the human fetal beta-cell. J. Clin. Endocrinol. Metab. 73, 1044-1050. doi:10.1210/jcem-73-5-1044
-
(1991)
J. Clin. Endocrinol. Metab.
, vol.73
, pp. 1044-1050
-
-
Tuch, B.E.1
Simpson, A.M.2
Campbell, I.L.3
-
71
-
-
33750502631
-
Induction of oral tolerance to oxidized lowdensity lipoprotein ameliorates atherosclerosis
-
doi:10.1161/CIRCULATIONAHA.106.615609
-
van Puijvelde, G. H., Hauer, A. D., De Vos, P., Van Den Heuvel, R., Van Herwijnen, M. J., Van Der Zee, R., et al. (2006). Induction of oral tolerance to oxidized lowdensity lipoprotein ameliorates atherosclerosis. Circulation 114, 1968-1976. doi:10.1161/CIRCULATIONAHA.106.615609
-
(2006)
Circulation
, vol.114
, pp. 1968-1976
-
-
van Puijvelde, G.H.1
Hauer, A.D.2
De Vos, P.3
Van Den Heuvel, R.4
Van Herwijnen, M.J.5
Van Der Zee, R.6
-
72
-
-
10644252898
-
Differential expression patterns of proinflammatory and antiinflammatory mediators during atherogenesis in mice
-
doi:10.1161/01.ATV.0000146532.98235.e6
-
Veillard, N. R., Steffens, S., Burger, F., Pelli, G., and Mach, F. (2004). Differential expression patterns of proinflammatory and antiinflammatory mediators during atherogenesis in mice. Arterioscler. Thromb. Vasc. Biol. 24, 2339-2344. doi:10.1161/01.ATV.0000146532.98235.e6
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 2339-2344
-
-
Veillard, N.R.1
Steffens, S.2
Burger, F.3
Pelli, G.4
Mach, F.5
-
73
-
-
0033537013
-
Elevated C-reactive protein levels in overweight and obese adults
-
doi:10.1001/jama.282.22.2131
-
Visser, M., Bouter, L. M., McQuillan, G. M., Wener, M. H., and Harris, T. B. (1999). Elevated C-reactive protein levels in overweight and obese adults. JAMA 282, 2131-2135. doi:10.1001/jama.282.22.2131
-
(1999)
JAMA
, vol.282
, pp. 2131-2135
-
-
Visser, M.1
Bouter, L.M.2
McQuillan, G.M.3
Wener, M.H.4
Harris, T.B.5
-
74
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
doi:10.1172/JCI19246
-
Weisberg, S. P., Mccann, D., Desai, M., Rosenbaum, M., Leibel, R. L., and Ferrante, A. W. Jr. (2003). Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112, 1796-1808. doi:10.1172/JCI19246
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
Mccann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.Jr.6
-
75
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
doi:10.1038/nm.2001
-
Winer, S., Chan, Y., Paltser, G., Truong, D., Tsui, H., Bahrami, J., et al. (2009). Normalization of obesity-associated insulin resistance through immunotherapy. Nat. Med. 15, 921-929. doi:10.1038/nm.2001
-
(2009)
Nat. Med.
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
Truong, D.4
Tsui, H.5
Bahrami, J.6
-
77
-
-
77951566030
-
Diabetes forum: extreme makeover of pancreatic alpha-cells
-
doi:10.1038/4641132a
-
Zaret, K. S., and White, M. F. (2010). Diabetes forum: extreme makeover of pancreatic alpha-cells. Nature 464, 1132-1133. doi:10.1038/4641132a
-
(2010)
Nature
, vol.464
, pp. 1132-1133
-
-
Zaret, K.S.1
White, M.F.2
-
78
-
-
34548354722
-
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
-
doi:10.1038/sj.ijo.0803632
-
Zeyda, M., Farmer, D., Todoric, J., Aszmann, O., Speiser, M., Gyori, G., et al. (2007). Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int. J. Obes. (Lond.) 31, 1420-1428. doi:10.1038/sj.ijo.0803632
-
(2007)
Int. J. Obes. (Lond.)
, vol.31
, pp. 1420-1428
-
-
Zeyda, M.1
Farmer, D.2
Todoric, J.3
Aszmann, O.4
Speiser, M.5
Gyori, G.6
-
79
-
-
79953204947
-
Inflammation correlates with markers of T-cell subsets including regulatory T cells in adipose tissue from obese patients
-
doi:10.1038/oby.2010.123
-
Zeyda, M., Huber, J., Prager, G., and Stulnig, T. M. (2011). Inflammation correlates with markers of T-cell subsets including regulatory T cells in adipose tissue from obese patients. Obesity (Silver Spring) 19, 743-748. doi:10.1038/oby.2010.123
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 743-748
-
-
Zeyda, M.1
Huber, J.2
Prager, G.3
Stulnig, T.M.4
-
80
-
-
69049107358
-
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
-
doi:10.1038/ni.1774
-
Zhou, X., Bailey-Bucktrout, S. L., Jeker, L. T., Penaranda, C., Martinez-Llordella, M., Ashby, M., et al. (2009). Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nat. Immunol. 10, 1000-1007. doi:10.1038/ni.1774
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1000-1007
-
-
Zhou, X.1
Bailey-Bucktrout, S.L.2
Jeker, L.T.3
Penaranda, C.4
Martinez-Llordella, M.5
Ashby, M.6
|