Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

Nature

Volumn 435, Issue 7039, 2005, Pages 220-223

  Nakayama, Maki ^a   Abiru, Norio ^b   Moriyama, Hiroaki ^c   Babaya, Naru ^a   Liu, Edwin ^a   Miao, Dongmei ^a   Yu, Liping ^a   Wegmann, Dale R ^a   Hutton, John C ^a   Elliott, John F ^d   Eisenbarth, George S ^a  

^a UNIVERSITY OF COLORADO DENVER   (United States)

^b NAGASAKI UNIVERSITY   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; DISEASE CONTROL; GENES; MATHEMATICAL MODELS; MOLECULES; PATHOLOGY;

AUTOANTIGENS; INSULIN EPITOPE; ISLET MOLECULES; PATHOGENESIS;

INSULIN;

ALANINE; AUTOANTIBODY; AUTOANTIGEN; EPITOPE; INSULIN; PROINSULIN;

DIABETES; MEDICINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CELL DESTRUCTION; CONTROLLED STUDY; EXPERIMENTAL MOUSE; FEMALE; GENE; GENE MUTATION; INSULIN 1 GENE; INSULIN 2 GENE; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; KNOCKOUT GENE; LYMPHOCYTE CLONE; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MALE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; ADOPTIVE TRANSFER; ANIMAL; CD4+ T LYMPHOCYTE; CYTOLOGY; DISEASE COURSE; GENETICS; GLUCOSE BLOOD LEVEL; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; SPLEEN; TRANSGENIC MOUSE;

ANIMALIA;

ADOPTIVE TRANSFER; ANIMALS; AUTOANTIBODIES; BLOOD GLUCOSE; CD4-POSITIVE T-LYMPHOCYTES; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; EPITOPES; FEMALE; INSULIN; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; MICE, TRANSGENIC; PROINSULIN; SPLEEN;

EID: 18744366947     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03523     Document Type: Article

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