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Volumn 6, Issue 9, 2011, Pages

Combining Antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted ß-cells in diabetic NOD mice

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ALUMINUM POTASSIUM SULFATE; DRINKING WATER; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE;

EID: 80053085802     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025337     Document Type: Article
Times cited : (39)

References (27)
  • 1
    • 77950649733 scopus 로고    scopus 로고
    • Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group
    • Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, (2010) Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin Exp Immunol 160: 176-184.
    • (2010) Clin Exp Immunol , vol.160 , pp. 176-184
    • Matthews, J.B.1    Staeva, T.P.2    Bernstein, P.L.3    Peakman, M.4    von Herrath, M.5
  • 2
    • 0033119044 scopus 로고    scopus 로고
    • GABA(A) receptors mediate inhibition of T cell responses
    • Tian J, Chau C, Hales TG, Kaufman DL, (1999) GABA(A) receptors mediate inhibition of T cell responses. J Neuroimmunol 96: 21-28.
    • (1999) J Neuroimmunol , vol.96 , pp. 21-28
    • Tian, J.1    Chau, C.2    Hales, T.G.3    Kaufman, D.L.4
  • 3
    • 6344285328 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid inhibits T cell autoimmunity and the development of inflammatory responses in a mouse type 1 diabetes model
    • Tian J, Lu Y, Zhang H, Chau CH, Dang HN, et al. (2004) Gamma-aminobutyric acid inhibits T cell autoimmunity and the development of inflammatory responses in a mouse type 1 diabetes model. J Immunol 173: 5298-5304.
    • (2004) J Immunol , vol.173 , pp. 5298-5304
    • Tian, J.1    Lu, Y.2    Zhang, H.3    Chau, C.H.4    Dang, H.N.5
  • 5
    • 80051498172 scopus 로고    scopus 로고
    • Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis
    • Tian J, Yong J, Dang H, Kaufman DL, (2011) Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis. Autoimmunity 44: 465-470.
    • (2011) Autoimmunity , vol.44 , pp. 465-470
    • Tian, J.1    Yong, J.2    Dang, H.3    Kaufman, D.L.4
  • 6
    • 80053078763 scopus 로고    scopus 로고
    • Oral treatment with γ-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice
    • (in press)
    • Tian J, Dang H, Yong J, Chui W-S, Dizon M, et al. (2011) Oral treatment with γ-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice. PLoS ONE (in press).
    • (2011) PLoS ONE
    • Tian, J.1    Dang, H.2    Yong, J.3    Chui, W.-S.4    Dizon, M.5
  • 7
    • 70349098142 scopus 로고    scopus 로고
    • Antigen-based therapy for the treatment of type 1 diabetes
    • Tian J, Kaufman DL, (2009) Antigen-based therapy for the treatment of type 1 diabetes. Diabetes 58: 1939-1946.
    • (2009) Diabetes , vol.58 , pp. 1939-1946
    • Tian, J.1    Kaufman, D.L.2
  • 8
    • 16144361909 scopus 로고    scopus 로고
    • Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice
    • Tian J, Clare-Salzler M, Herschenfeld A, Middleton B, Newman D, et al. (1996) Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice. Nat Med 2: 1348-1353.
    • (1996) Nat Med , vol.2 , pp. 1348-1353
    • Tian, J.1    Clare-Salzler, M.2    Herschenfeld, A.3    Middleton, B.4    Newman, D.5
  • 9
    • 34248210131 scopus 로고    scopus 로고
    • The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice
    • Pop SM, Wong CP, He Q, Wang Y, Wallet MA, et al. (2007) The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice. Diabetes 56: 1395-1402.
    • (2007) Diabetes , vol.56 , pp. 1395-1402
    • Pop, S.M.1    Wong, C.P.2    He, Q.3    Wang, Y.4    Wallet, M.A.5
  • 10
    • 0344915162 scopus 로고    scopus 로고
    • Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response
    • Yip HC, Karulin AY, Tary-Lehmann M, Hesse MD, Radeke H, et al. (1999) Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response. J Immunol 162: 3942-3949.
    • (1999) J Immunol , vol.162 , pp. 3942-3949
    • Yip, H.C.1    Karulin, A.Y.2    Tary-Lehmann, M.3    Hesse, M.D.4    Radeke, H.5
  • 11
    • 22544454139 scopus 로고    scopus 로고
    • Antigen-based therapies using ignored determinants of beta cell antigens can more effectively inhibit late-stage autoimmune disease in diabetes-prone mice
    • Olcott AP, Tian J, Walker V, Dang H, Middleton B, et al. (2005) Antigen-based therapies using ignored determinants of beta cell antigens can more effectively inhibit late-stage autoimmune disease in diabetes-prone mice. J Immunol 175: 1991-1999.
    • (2005) J Immunol , vol.175 , pp. 1991-1999
    • Olcott, A.P.1    Tian, J.2    Walker, V.3    Dang, H.4    Middleton, B.5
  • 12
    • 40949147034 scopus 로고    scopus 로고
    • Combination therapy with epidermal growth factor and gastrin delays autoimmune diabetes recurrence in nonobese diabetic mice transplanted with syngeneic islets
    • Suarez-Pinzon WL, Rabinovitch A, (2008) Combination therapy with epidermal growth factor and gastrin delays autoimmune diabetes recurrence in nonobese diabetic mice transplanted with syngeneic islets. Transplant Proc 40: 529-532.
    • (2008) Transplant Proc , vol.40 , pp. 529-532
    • Suarez-Pinzon, W.L.1    Rabinovitch, A.2
  • 13
    • 21344461521 scopus 로고    scopus 로고
    • Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes
    • Agardh CD, Cilio CM, Lethagen A, Lynch K, Leslie RD, et al. (2005) Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes. J Diabetes Complications 19: 238-246.
    • (2005) J Diabetes Complications , vol.19 , pp. 238-246
    • Agardh, C.D.1    Cilio, C.M.2    Lethagen, A.3    Lynch, K.4    Leslie, R.D.5
  • 14
    • 55249110198 scopus 로고    scopus 로고
    • GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes
    • Ludvigsson J, Faresjo M, Hjorth M, Axelsson S, Cheramy M, et al. (2008) GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes. N Engl J Med 359: 1909-1920.
    • (2008) N Engl J Med , vol.359 , pp. 1909-1920
    • Ludvigsson, J.1    Faresjo, M.2    Hjorth, M.3    Axelsson, S.4    Cheramy, M.5
  • 15
    • 79960743608 scopus 로고    scopus 로고
    • Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial
    • Wherrett DK, Bundy B, Becker DJ, Dimeglio LA, Gitelman SE, et al. (2011) Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial. Lancet 378: 319-327.
    • (2011) Lancet , vol.378 , pp. 319-327
    • Wherrett, D.K.1    Bundy, B.2    Becker, D.J.3    Dimeglio, L.A.4    Gitelman, S.E.5
  • 16
    • 0027411109 scopus 로고
    • Suppressive effect of GABA on insulin secretion from the pancreatic beta-cells in the rat
    • Gu XH, Kurose T, Kato S, Masuda K, Tsuda K, et al. (1993) Suppressive effect of GABA on insulin secretion from the pancreatic beta-cells in the rat. Life Sci 52: 687-694.
    • (1993) Life Sci , vol.52 , pp. 687-694
    • Gu, X.H.1    Kurose, T.2    Kato, S.3    Masuda, K.4    Tsuda, K.5
  • 17
    • 0024470349 scopus 로고
    • Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels
    • Rorsman P, Berggren PO, Bokvist K, Ericson H, Mohler H, et al. (1989) Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels. Nature 341: 233-236.
    • (1989) Nature , vol.341 , pp. 233-236
    • Rorsman, P.1    Berggren, P.O.2    Bokvist, K.3    Ericson, H.4    Mohler, H.5
  • 18
    • 77954252193 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells
    • Braun M, Ramracheya R, Bengtsson M, Clark A, Walker JN, et al. (2010) Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells. Diabetes 59: 1694-1701.
    • (2010) Diabetes , vol.59 , pp. 1694-1701
    • Braun, M.1    Ramracheya, R.2    Bengtsson, M.3    Clark, A.4    Walker, J.N.5
  • 19
    • 33847686231 scopus 로고    scopus 로고
    • Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid
    • Ligon B, Yang J, Morin SB, Ruberti MF, Steer ML, (2007) Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid. Diabetologia 50: 764-773.
    • (2007) Diabetologia , vol.50 , pp. 764-773
    • Ligon, B.1    Yang, J.2    Morin, S.B.3    Ruberti, M.F.4    Steer, M.L.5
  • 20
    • 79960996764 scopus 로고    scopus 로고
    • GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes
    • Soltani N, Qiu H, Aleksic M, Glinka Y, Zhao F, et al. (2011) GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes. Proc Natl Acad Sci U S A 108: 11692-11697.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 11692-11697
    • Soltani, N.1    Qiu, H.2    Aleksic, M.3    Glinka, Y.4    Zhao, F.5
  • 21
    • 77956360380 scopus 로고    scopus 로고
    • Antigen-specific immunotherapy for type 1 diabetes: maximizing the potential
    • Peakman M, von Herrath M, (2010) Antigen-specific immunotherapy for type 1 diabetes: maximizing the potential. Diabetes 59: 2087-2093.
    • (2010) Diabetes , vol.59 , pp. 2087-2093
    • Peakman, M.1    von Herrath, M.2
  • 22
    • 0028965645 scopus 로고
    • Potassium and calcium channels in lymphocytes
    • Lewis RS, Cahalan MD, (1995) Potassium and calcium channels in lymphocytes. Annu Rev Immunol 13: 623-653.
    • (1995) Annu Rev Immunol , vol.13 , pp. 623-653
    • Lewis, R.S.1    Cahalan, M.D.2
  • 23
  • 24
    • 0019509515 scopus 로고
    • Clinical evaluation of GABA in the treatment of cerebrovascular disorders. Multi-center double-blind study in comparison with pyrithioxine and placebo
    • Otomo E, Araki G, Mori A, Kurihara M, (1981) Clinical evaluation of GABA in the treatment of cerebrovascular disorders. Multi-center double-blind study in comparison with pyrithioxine and placebo. Arzneimittelforschung 31: 1511-1523.
    • (1981) Arzneimittelforschung , vol.31 , pp. 1511-1523
    • Otomo, E.1    Araki, G.2    Mori, A.3    Kurihara, M.4
  • 25
    • 0023550455 scopus 로고
    • Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients
    • Loeb C, Benassi E, Bo GP, Cocito L, Maffini M, et al. (1987) Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res 1: 209-212.
    • (1987) Epilepsy Res , vol.1 , pp. 209-212
    • Loeb, C.1    Benassi, E.2    Bo, G.P.3    Cocito, L.4    Maffini, M.5
  • 26
    • 0042085354 scopus 로고
    • Inhibition in the Nervous System and GABA
    • New York, Pergamon Press
    • Tower DB, Roberts E, eds. (1960) Inhibition in the Nervous System and GABA. New York Pergamon Press pp. 562-578.
    • (1960) , pp. 562-578
    • Tower, D.B.1    Roberts, E.2
  • 27
    • 33644817555 scopus 로고    scopus 로고
    • Human peripheral blood mononuclear cells express GABAA receptor subunits
    • Alam S, Laughton DL, Walding A, Wolstenholme AJ, (2006) Human peripheral blood mononuclear cells express GABAA receptor subunits. Mol Immunol 43: 1432-1442.
    • (2006) Mol Immunol , vol.43 , pp. 1432-1442
    • Alam, S.1    Laughton, D.L.2    Walding, A.3    Wolstenholme, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.