메뉴 건너뛰기




Volumn 13, Issue 8, 2013, Pages 566-577

The role of dendritic cells in autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN PRESENTATION; AUTOIMMUNE DISEASE; AUTOIMMUNE MYOCARDITIS; AUTOIMMUNITY; DENDRITIC CELL; GENE TARGETING; HUMAN; IMMUNOLOGICAL TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; MULTIPLE SCLEROSIS; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PSORIASIS; REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS; THYMOCYTE;

EID: 84880924243     PISSN: 14741733     EISSN: 14741741     Source Type: Journal    
DOI: 10.1038/nri3477     Document Type: Review
Times cited : (407)

References (118)
  • 1
    • 84857793524 scopus 로고    scopus 로고
    • Decisions about dendritic cells: Past, present, and future
    • Steinman, R. M. Decisions about dendritic cells: past, present, and future. Annu. Rev. Immunol. 30, 1-22 (2012).
    • (2012) Annu. Rev. Immunol , vol.30 , pp. 1-22
    • Steinman, R.M.1
  • 2
    • 80053156515 scopus 로고    scopus 로고
    • Dendritic cell and macrophage heterogeneity in vivo
    • Hashimoto, D., Miller, J. & Merad, M. Dendritic cell and macrophage heterogeneity in vivo. Immunity 35, 323-335 (2011).
    • (2011) Immunity , vol.35 , pp. 323-335
    • Hashimoto, D.1    Miller, J.2    Merad, M.3
  • 4
    • 84865639341 scopus 로고    scopus 로고
    • Dendritic cells: Arbiters of immunity and immunological tolerance
    • Lewis, K. L. & Reizis, B. Dendritic cells: arbiters of immunity and immunological tolerance. Cold Spring Harb. Perspect. Biol. 4, a007401 (2012).
    • (2012) Cold Spring Harb. Perspect. Biol , vol.4
    • Lewis, K.L.1    Reizis, B.2
  • 6
    • 84874234535 scopus 로고    scopus 로고
    • Human inflammatory dendritic cells induce Th17 cell differentiation
    • Segura, E. et al. Human inflammatory dendritic cells induce Th17 cell differentiation. Immunity 38, 336-348 (2013).
    • (2013) Immunity , vol.38 , pp. 336-348
    • Segura, E.1
  • 7
    • 84861750928 scopus 로고    scopus 로고
    • Characterization of resident and migratory dendritic cells in human lymph nodes
    • Segura, E. et al. Characterization of resident and migratory dendritic cells in human lymph nodes. J. Exp. Med. 209, 653-660 (2012).
    • (2012) J. Exp. Med , vol.209 , pp. 653-660
    • Segura, E.1
  • 8
    • 0021055656 scopus 로고
    • Ia-expressing cells and T lymphocytes of different subsets in peripheral nerve tissues during experimental allergic neuritis in Lewis rats
    • Olsson, T., Holmdahl, R., Klareskog, L. & Forsum, U. Ia-expressing cells and T lymphocytes of different subsets in peripheral nerve tissue during experimental allergic neuritis in Lewis rats. Scand. J. Immunol. 18, 339-343 (1983). (Pubitemid 14240188)
    • (1983) Scandinavian Journal of Immunology , vol.18 , Issue.4 , pp. 339-343
    • Olsson, T.1    Holmdahl, R.2    Klareskog, L.3    Forsum, U.4
  • 9
    • 0010592446 scopus 로고
    • Induction of immune responses in vivo with small numbers of veiled (dendritic) cells
    • Knight, S. C., Mertin, J., Stackpoole, A. & Clark, J. Induction of immune responses in vivo with small numbers of veiled (dendritic) cells. Proc. Natl Acad. Sci. USA 80, 6032-6035 (1983). This paper shows that 'veiled cells' (that is, DCs) from animals with EAE could transfer the disease to naive recipients, which establishes the capacity of DCs to prime autoreactive T cell responses. (Pubitemid 14228238)
    • (1983) Proceedings of the National Academy of Sciences of the United States of America , vol.80 , Issue.19 , pp. 6032-6035
    • Knight, S.C.1    Mertin, J.2    Stackpoole, A.3    Clark, J.4
  • 10
    • 7244227645 scopus 로고    scopus 로고
    • Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
    • DOI 10.1084/jem.20041457
    • Gallegos, A. M. & Bevan, M. J. Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation. J. Exp. Med. 200, 1039-1049 (2004). (Pubitemid 39431128)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.8 , pp. 1039-1049
    • Gallegos, A.M.1    Bevan, M.J.2
  • 11
    • 80052423824 scopus 로고    scopus 로고
    • Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance
    • Hubert, F. X. et al. Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance. Blood 118, 2462-2472 (2011).
    • (2011) Blood , vol.118 , pp. 2462-2472
    • Hubert, F.X.1
  • 12
    • 79951715831 scopus 로고    scopus 로고
    • Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
    • Lei, Y. et al. Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. J. Exp. Med. 208, 383-394 (2011).
    • (2011) J. Exp. Med , vol.208 , pp. 383-394
    • Lei, Y.1
  • 13
    • 79955625097 scopus 로고    scopus 로고
    • Autonomous versus dendritic cell-dependent contributions of medullary thymic epithelial cells to central tolerance
    • Klein, L., Hinterberger, M., von Rohrscheidt, J. & Aichinger, M. Autonomous versus dendritic cell-dependent contributions of medullary thymic epithelial cells to central tolerance. Trends Immunol. 32, 188-193 (2011).
    • (2011) Trends Immunol , vol.32 , pp. 188-193
    • Klein, L.1    Hinterberger, M.2    Von Rohrscheidt, J.3    Aichinger, M.4
  • 14
    • 57449109064 scopus 로고    scopus 로고
    • Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome
    • Birnberg, T. et al. Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome. Immunity 29, 986-997 (2008). This paper shows that the constitutive ablation of cDCs does not breach central or peripheral tolerance or induce overt autoimmunity.
    • (2008) Immunity , vol.29 , pp. 986-997
    • Birnberg, T.1
  • 16
    • 58149376454 scopus 로고    scopus 로고
    • Dendritic cells in the thymus contribute to T-regulatory cell induction
    • Proietto, A. I. et al. Dendritic cells in the thymus contribute to T-regulatory cell induction. Proc. Natl Acad. Sci. USA 105, 19869-19874 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 19869-19874
    • Proietto, A.I.1
  • 18
    • 2942523789 scopus 로고    scopus 로고
    • Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo
    • DOI 10.1016/j.immuni.2004.05.002, PII S1074761304001359
    • Hawiger, D., Masilamani, R. F., Bettelli, E., Kuchroo, V. K. & Nussenzweig, M. C. Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo. Immunity 20, 695-705 (2004). (Pubitemid 38757440)
    • (2004) Immunity , vol.20 , Issue.6 , pp. 695-705
    • Hawiger, D.1    Masilamani, R.F.2    Bettelli, E.3    Kuchroo, V.K.4    Nussenzweig, M.C.5
  • 19
    • 0038325761 scopus 로고    scopus 로고
    • + T cell tolerance
    • DOI 10.1016/S1074-7613(03)00120-1
    • Probst, H. C., Lagnel, J., Kollias, G. & van den Broek, M. Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance. Immunity 18, 713-720 (2003). This paper further shows the tolerogenic capacity of DCs in the steady state by genetically targeting antigens to DCs. (Pubitemid 36588587)
    • (2003) Immunity , vol.18 , Issue.5 , pp. 713-720
    • Probst, H.C.1    Lagnel, J.2    Kollias, G.3    Van Den Broek, M.4
  • 20
    • 14944360112 scopus 로고    scopus 로고
    • + T cell tolerance through PD-1 and CTLA-4
    • DOI 10.1038/ni1165
    • Probst, H. C., McCoy, K., Okazaki, T., Honjo, T. & van den Broek, M. Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4. Nature Immunol. 6, 280-286 (2005). (Pubitemid 41724765)
    • (2005) Nature Immunology , vol.6 , Issue.3 , pp. 280-286
    • Probst, H.C.1    McCoy, K.2    Okazaki, T.3    Honjo, T.4    Van Den Broek, M.5
  • 21
    • 84861861151 scopus 로고    scopus 로고
    • Release of dendritic cells from cognate CD4+ T-cell recognition results in impaired peripheral tolerance and fatal cytotoxic T-cell mediated autoimmunity
    • Muth, S., Schutze, K., Schild, H. & Probst, H. C. Release of dendritic cells from cognate CD4+ T-cell recognition results in impaired peripheral tolerance and fatal cytotoxic T-cell mediated autoimmunity. Proc. Natl Acad. Sci. USA 109, 9059-9064 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 9059-9064
    • Muth, S.1    Schutze, K.2    Schild, H.3    Probst, H.C.4
  • 23
    • 84855472967 scopus 로고    scopus 로고
    • Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice
    • Sela, U., Olds, P., Park, A., Schlesinger, S. J. & Steinman, R. M. Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice. J. Exp. Med. 208, 2489-2496 (2011).
    • (2011) J. Exp. Med , vol.208 , pp. 2489-2496
    • Sela, U.1    Olds, P.2    Park, A.3    Schlesinger, S.J.4    Steinman, R.M.5
  • 24
    • 77949900562 scopus 로고    scopus 로고
    • Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice
    • Suffner, J. et al. Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice. J. Immunol. 184, 1810-1820 (2010).
    • (2010) J. Immunol , vol.184 , pp. 1810-1820
    • Suffner, J.1
  • 25
    • 78851471170 scopus 로고    scopus 로고
    • Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation
    • Bar-On, L., Birnberg, T., Kim, K. W. & Jung, S. Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation. Eur. J. Immunol. 41, 291-298 (2011).
    • (2011) Eur. J. Immunol , vol.41 , pp. 291-298
    • Bar-On, L.1    Birnberg, T.2    Kim, K.W.3    Jung, S.4
  • 26
    • 84865277279 scopus 로고    scopus 로고
    • Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells
    • Vitali, C. et al. Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells. Blood 120, 1237-1245 (2012).
    • (2012) Blood , vol.120 , pp. 1237-1245
    • Vitali, C.1
  • 27
    • 69549103141 scopus 로고    scopus 로고
    • Feedback control of regulatory T cell homeostasis by dendritic cells in vivo
    • Darrasse-Jeze, G. et al. Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. J. Exp. Med. 206, 1853-1862 (2009).
    • (2009) J. Exp. Med , vol.206 , pp. 1853-1862
    • Darrasse-Jeze, G.1
  • 28
    • 67650638850 scopus 로고    scopus 로고
    • Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment
    • Swee, L. K., Bosco, N., Malissen, B., Ceredig, R. & Rolink, A. Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment. Blood 113, 6277-6287 (2009).
    • (2009) Blood , vol.113 , pp. 6277-6287
    • Swee, L.K.1    Bosco, N.2    Malissen, B.3    Ceredig, R.4    Rolink, A.5
  • 29
    • 84863717726 scopus 로고    scopus 로고
    • Flt3 ligand expands CD103+ dendritic cells and FoxP3+ T regulatory cells, and attenuates Crohn's-like murine ileitis
    • Collins, C. B. et al. Flt3 ligand expands CD103+ dendritic cells and FoxP3+ T regulatory cells, and attenuates Crohn's-like murine ileitis. Gut 61, 1154-1162 (2011).
    • (2011) Gut , vol.61 , pp. 1154-1162
    • Collins, C.B.1
  • 30
    • 84857733624 scopus 로고    scopus 로고
    • Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c+ CD11b+ dendritic cells
    • Kriegel, M. A., Rathinam, C. & Flavell, R. A. Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c+ CD11b+ dendritic cells. Proc. Natl Acad. Sci. USA 109, 3457-3462 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 3457-3462
    • Kriegel, M.A.1    Rathinam, C.2    Flavell, R.A.3
  • 31
    • 77349083495 scopus 로고    scopus 로고
    • Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells
    • Edelson, B. T. et al. Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells. J. Exp. Med. 207, 823-836 (2010).
    • (2010) J. Exp. Med , vol.207 , pp. 823-836
    • Edelson, B.T.1
  • 32
    • 81955164775 scopus 로고    scopus 로고
    • Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine
    • Lewis, K. L. et al. Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity 35, 780-791 (2011).
    • (2011) Immunity , vol.35 , pp. 780-791
    • Lewis, K.L.1
  • 33
    • 84865418252 scopus 로고    scopus 로고
    • Deletion of cognate CD8 T cells by immature dendritic cells: A novel role for perforin, granzyme A, TREM-1, and TLR7
    • Zangi, L. et al. Deletion of cognate CD8 T cells by immature dendritic cells: a novel role for perforin, granzyme A, TREM-1, and TLR7. Blood 120, 1647-1657 (2012).
    • (2012) Blood , vol.120 , pp. 1647-1657
    • Zangi, L.1
  • 34
    • 63449108301 scopus 로고    scopus 로고
    • Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
    • Ohnmacht, C. et al. Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J. Exp. Med. 206, 549-559 (2009).
    • (2009) J. Exp. Med , vol.206 , pp. 549-559
    • Ohnmacht, C.1
  • 35
    • 78650108453 scopus 로고    scopus 로고
    • Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage
    • Teichmann, L. L. et al. Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage. Immunity 33, 967-978 (2010).
    • (2010) Immunity , vol.33 , pp. 967-978
    • Teichmann, L.L.1
  • 36
    • 84857426963 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells control T-cell response to chronic viral infection
    • Cervantes-Barragan, L. et al. Plasmacytoid dendritic cells control T-cell response to chronic viral infection. Proc. Natl Acad. Sci. USA 109, 3012-3017 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 3012-3017
    • Cervantes-Barragan, L.1
  • 37
    • 33644502594 scopus 로고    scopus 로고
    • Dendritic cell apoptosis in the maintenance of immune tolerance
    • Chen, M. et al. Dendritic cell apoptosis in the maintenance of immune tolerance. Science 311, 1160-1164 (2006).
    • (2006) Science , vol.311 , pp. 1160-1164
    • Chen, M.1
  • 39
    • 82755192217 scopus 로고    scopus 로고
    • Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells
    • Chen, M., Felix, K. & Wang, J. Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells. J. Immunol. 187, 5684-5692 (2011).
    • (2011) J. Immunol , vol.187 , pp. 5684-5692
    • Chen, M.1    Felix, K.2    Wang, J.3
  • 41
    • 77951886963 scopus 로고    scopus 로고
    • Dendritic cell (DC)-specific targeting reveals Stat3 as a negative regulator of DC function
    • Melillo, J. A. et al. Dendritic cell (DC)-specific targeting reveals Stat3 as a negative regulator of DC function. J. Immunol. 184, 2638-2645 (2010).
    • (2010) J. Immunol , vol.184 , pp. 2638-2645
    • Melillo, J.A.1
  • 42
  • 43
    • 81255160601 scopus 로고    scopus 로고
    • Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis
    • Hammer, G. E. et al. Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. Nature Immunol. 12, 1184-1193 (2011).
    • (2011) Nature Immunol , vol.12 , pp. 1184-1193
    • Hammer, G.E.1
  • 44
    • 79960467121 scopus 로고    scopus 로고
    • The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity
    • Kool, M. et al. The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity. Immunity 35, 82-96 (2011).
    • (2011) Immunity , vol.35 , pp. 82-96
    • Kool, M.1
  • 45
    • 84862092310 scopus 로고    scopus 로고
    • Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity
    • Kaneko, T. et al. Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity. J. Immunol. 188, 5397-5407 (2012).
    • (2012) J. Immunol , vol.188 , pp. 5397-5407
    • Kaneko, T.1
  • 46
    • 84875532599 scopus 로고    scopus 로고
    • Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice
    • Abram, C. L., Roberge, G. L., Pao, L. I., Neel, B. G. & Lowell, C. A. Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice. Immunity 38, 489-501 (2013).
    • (2013) Immunity , vol.38 , pp. 489-501
    • Abram, C.L.1    Roberge, G.L.2    Pao, L.I.3    Neel, B.G.4    Lowell, C.A.5
  • 49
    • 53349143503 scopus 로고    scopus 로고
    • GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival
    • Sonderegger, I. et al. GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival. J. Exp. Med. 205, 2281-2294 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 2281-2294
    • Sonderegger, I.1
  • 50
    • 77952537201 scopus 로고    scopus 로고
    • Contribution of TLR7 and TLR9 signaling to the susceptibility of MyD88-deficient mice to myocarditis
    • Pagni, P. P., Traub, S., Demaria, O., Chasson, L. & Alexopoulou, L. Contribution of TLR7 and TLR9 signaling to the susceptibility of MyD88-deficient mice to myocarditis. Autoimmunity 43, 275-287 (2010).
    • (2010) Autoimmunity , vol.43 , pp. 275-287
    • Pagni, P.P.1    Traub, S.2    Demaria, O.3    Chasson, L.4    Alexopoulou, L.5
  • 51
    • 83755173455 scopus 로고    scopus 로고
    • The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis
    • Popovic, Z. V. et al. The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis. J. Immunol. 187, 6217-6226 (2011).
    • (2011) J. Immunol , vol.187 , pp. 6217-6226
    • Popovic, Z.V.1
  • 52
    • 16244417773 scopus 로고    scopus 로고
    • Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
    • DOI 10.1038/nm1202
    • McMahon, E. J., Bailey, S. L., Castenada, C. V., Waldner, H. & Miller, S. D. Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nature Med. 11, 335-339 (2005). (Pubitemid 40460563)
    • (2005) Nature Medicine , vol.11 , Issue.3 , pp. 335-339
    • McMahon, E.J.1    Bailey, S.L.2    Castenada, C.V.3    Waldner, H.4    Miller, S.D.5
  • 54
    • 79151481102 scopus 로고    scopus 로고
    • Limited sufficiency of antigen presentation by dendritic cells in models of central nervous system autoimmunity
    • Wu, G. F. et al. Limited sufficiency of antigen presentation by dendritic cells in models of central nervous system autoimmunity. J. Autoimmun. 36, 56-64 (2011).
    • (2011) J. Autoimmun , vol.36 , pp. 56-64
    • Wu, G.F.1
  • 55
    • 84865391725 scopus 로고    scopus 로고
    • Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor+ regulatory T cells
    • Yogev, N. et al. Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor+ regulatory T cells. Immunity 37, 264-275 (2012). This paper shows the overall anti-inflammatory role of cDCs in EAE using various DC ablation methods.
    • (2012) Immunity , vol.37 , pp. 264-275
    • Yogev, N.1
  • 56
    • 84867191763 scopus 로고    scopus 로고
    • Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE
    • Isaksson, M., Lundgren, B. A., Ahlgren, K. M., Kampe, O. & Lobell, A. Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE. Eur. J. Immunol. 42, 2555-2563 (2012).
    • (2012) Eur. J. Immunol , vol.42 , pp. 2555-2563
    • Isaksson, M.1    Lundgren, B.A.2    Ahlgren, K.M.3    Kampe, O.4    Lobell, A.5
  • 57
    • 84855929741 scopus 로고    scopus 로고
    • Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation
    • Huang, G. et al. Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation. Nature Immunol. 13, 152-161 (2012).
    • (2012) Nature Immunol , vol.13 , pp. 152-161
    • Huang, G.1
  • 58
    • 78649807601 scopus 로고    scopus 로고
    • Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice
    • Melton, A. C. et al. Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice. J. Clin. Invest. 120, 4436-4444 (2010).
    • (2010) J. Clin. Invest , vol.120 , pp. 4436-4444
    • Melton, A.C.1
  • 59
    • 49449116101 scopus 로고    scopus 로고
    • TGF-β signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis
    • Laouar, Y. et al. TGF-β signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proc. Natl Acad. Sci. USA 105, 10865-10870 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 10865-10870
    • Laouar, Y.1
  • 60
    • 79957556982 scopus 로고    scopus 로고
    • Tim-1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells
    • Xiao, S. et al. Tim-1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells. Eur. J. Immunol. 41, 1539-1549 (2011).
    • (2011) Eur. J. Immunol , vol.41 , pp. 1539-1549
    • Xiao, S.1
  • 61
    • 43049101640 scopus 로고    scopus 로고
    • The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
    • DOI 10.1172/JCI33342
    • Guo, B., Chang, E. Y. & Cheng, G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest. 118, 1680-1690 (2008). (Pubitemid 351632372)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.5 , pp. 1680-1690
    • Guo, B.1    Chang, E.Y.2    Cheng, G.3
  • 62
    • 84655170111 scopus 로고    scopus 로고
    • Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS
    • Dann, A. et al. Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS. Nature Neurosci. 15, 98-106 (2012).
    • (2012) Nature Neurosci , vol.15 , pp. 98-106
    • Dann, A.1
  • 63
    • 77951634161 scopus 로고    scopus 로고
    • IFN-β inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9
    • Yen, J. H., Kong, W. & Ganea, D. IFN-β inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9. J. Immunol. 184, 3478-3486 (2010).
    • (2010) J. Immunol , vol.184 , pp. 3478-3486
    • Yen, J.H.1    Kong, W.2    Ganea, D.3
  • 64
    • 79961160742 scopus 로고    scopus 로고
    • Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
    • Anandasabapathy, N. et al. Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain. J. Exp. Med. 208, 1695-1705 (2011).
    • (2011) J. Exp. Med , vol.208 , pp. 1695-1705
    • Anandasabapathy, N.1
  • 65
    • 79953675959 scopus 로고    scopus 로고
    • CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system
    • Prodinger, C. et al. CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system. Acta Neuropathol. 121, 445-458 (2011).
    • (2011) Acta Neuropathol , vol.121 , pp. 445-458
    • Prodinger, C.1
  • 66
    • 33846472053 scopus 로고    scopus 로고
    • H-17 cells in relapsing EAE
    • DOI 10.1038/ni1430, PII NI1430
    • Bailey, S. L., Schreiner, B., McMahon, E. J. & Miller, S. D. CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ TH-17 cells in relapsing EAE. Nature Immunol. 8, 172-180 (2007). (Pubitemid 46152648)
    • (2007) Nature Immunology , vol.8 , Issue.2 , pp. 172-180
    • Bailey, S.L.1    Schreiner, B.2    McMahon, E.J.3    Miller, S.D.4
  • 67
    • 84857938454 scopus 로고    scopus 로고
    • CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells
    • Poppensieker, K. et al. CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells. Proc. Natl Acad. Sci. USA 109, 3897-3902 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 3897-3902
    • Poppensieker, K.1
  • 68
    • 79956116032 scopus 로고    scopus 로고
    • RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
    • Codarri, L. et al. RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nature Immunol. 12, 560-567 (2011).
    • (2011) Nature Immunol , vol.12 , pp. 560-567
    • Codarri, L.1
  • 69
    • 79956152607 scopus 로고    scopus 로고
    • The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
    • El-Behi, M. et al. The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nature Immunol. 12, 568-575 (2011).
    • (2011) Nature Immunol , vol.12 , pp. 568-575
    • El-Behi, M.1
  • 70
    • 45549095991 scopus 로고    scopus 로고
    • Cutting edge: Central nervous system plasmacytoid dendritic cells regulate the severity of relapsing experimental autoimmune encephalomyelitis
    • Bailey-Bucktrout, S. L. et al. Cutting edge: central nervous system plasmacytoid dendritic cells regulate the severity of relapsing experimental autoimmune encephalomyelitis. J. Immunol. 180, 6457-6461 (2008).
    • (2008) J. Immunol , vol.180 , pp. 6457-6461
    • Bailey-Bucktrout, S.L.1
  • 71
    • 77956098825 scopus 로고    scopus 로고
    • MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity
    • Irla, M. et al. MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity. J. Exp. Med. 207, 1891-1905 (2010). Genetic ablation of MHC class II expression specifically in pDCs shows that pDCs might promote TReg cell development and they might inhibit inflammation in EAE.
    • (2010) J. Exp. Med , vol.207 , pp. 1891-1905
    • Irla, M.1
  • 72
    • 33748510173 scopus 로고    scopus 로고
    • Innate immunity in multiple sclerosis: Myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response
    • Karni, A. et al. Innate immunity in multiple sclerosis: myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response. J. Immunol. 177, 4196-4202 (2006). (Pubitemid 44359955)
    • (2006) Journal of Immunology , vol.177 , Issue.6 , pp. 4196-4202
    • Karni, A.1    Abraham, M.2    Monsonego, A.3    Cai, G.4    Freeman, G.J.5    Hafler, D.6    Khoury, S.J.7    Weiner, H.L.8
  • 73
    • 80755180843 scopus 로고    scopus 로고
    • Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation
    • Cai, Y. et al. Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation. Immunity 35, 596-610 (2011).
    • (2011) Immunity , vol.35 , pp. 596-610
    • Cai, Y.1
  • 74
    • 84861801523 scopus 로고    scopus 로고
    • Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice
    • Pantelyushin, S. et al. Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice. J. Clin. Invest. 122, 2252-2256 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 2252-2256
    • Pantelyushin, S.1
  • 75
    • 66949162673 scopus 로고    scopus 로고
    • Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis
    • van der Fits, L. et al. Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. J. Immunol. 182, 5836-5845 (2009).
    • (2009) J. Immunol , vol.182 , pp. 5836-5845
    • Van Der Fits, L.1
  • 76
    • 84875878203 scopus 로고    scopus 로고
    • Aldara activates TLR7-independent immune defence
    • Walter, A. et al. Aldara activates TLR7-independent immune defence. Nature Commun. 4, 1560 (2013).
    • (2013) Nature Commun , vol.4 , pp. 1560
    • Walter, A.1
  • 77
    • 84868613788 scopus 로고    scopus 로고
    • Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk
    • Tortola, L. et al. Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk. J. Clin. Invest. 122, 3965-3976 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 3965-3976
    • Tortola, L.1
  • 79
    • 60549117538 scopus 로고    scopus 로고
    • Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment
    • Albanesi, C. et al. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J. Exp. Med. 206, 249-258 (2009).
    • (2009) J. Exp. Med , vol.206 , pp. 249-258
    • Albanesi, C.1
  • 80
    • 78650315462 scopus 로고    scopus 로고
    • Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9
    • Guiducci, C. et al. Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9. J. Exp. Med. 207, 2931-2942 (2010).
    • (2010) J. Exp. Med , vol.207 , pp. 2931-2942
    • Guiducci, C.1
  • 81
    • 78650409670 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense skin injury and promote wound healing through type i interferons
    • Gregorio, J. et al. Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons. J. Exp. Med. 207, 2921-2930 (2010).
    • (2010) J. Exp. Med , vol.207 , pp. 2921-2930
    • Gregorio, J.1
  • 83
    • 69549135324 scopus 로고    scopus 로고
    • Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
    • Ganguly, D. et al. Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. J. Exp. Med. 206, 1983-1994 (2009).
    • (2009) J. Exp. Med , vol.206 , pp. 1983-1994
    • Ganguly, D.1
  • 85
    • 0345448056 scopus 로고    scopus 로고
    • Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model
    • DOI 10.1084/jem.20030966
    • Turley, S., Poirot, L., Hattori, M., Benoist, C. & Mathis, D. Physiological β-cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J. Exp. Med. 198, 1527-1537 (2003). This paper established the role of DCs in the presentation of β-islet cell antigens to self-reactive T cells in experimental diabetes. (Pubitemid 37467167)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.10 , pp. 1527-1537
    • Turley, S.1    Poirot, L.2    Hattori, M.3    Benoist, C.4    Mathis, D.5
  • 86
    • 38449111402 scopus 로고    scopus 로고
    • The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse
    • Saxena, V., Ondr, J. K., Magnusen, A. F., Munn, D. H. & Katz, J. D. The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse. J. Immunol. 179, 5041-5053 (2007).
    • (2007) J. Immunol , vol.179 , pp. 5041-5053
    • Saxena, V.1    Ondr, J.K.2    Magnusen, A.F.3    Munn, D.H.4    Katz, J.D.5
  • 88
    • 50849096898 scopus 로고    scopus 로고
    • Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice
    • Han, J. et al. Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice. Diabetes 57, 2118-2127 (2008).
    • (2008) Diabetes , vol.57 , pp. 2118-2127
    • Han, J.1
  • 90
    • 27644470987 scopus 로고    scopus 로고
    • The role of TNF-α in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: Analysis of dendritic cell maturation
    • Lee, L. F. et al. The role of TNF-α in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation. Proc. Natl Acad. Sci. USA 102, 15995-16000 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 15995-16000
    • Lee, L.F.1
  • 91
    • 84863006210 scopus 로고    scopus 로고
    • Interleukin-21 receptor-mediated signals control autoreactive T cell infiltration in pancreatic islets
    • Van Belle, T. L., Nierkens, S., Arens, R. & von Herrath, M. G. Interleukin-21 receptor-mediated signals control autoreactive T cell infiltration in pancreatic islets. Immunity 36, 1060-1072 (2012).
    • (2012) Immunity , vol.36 , pp. 1060-1072
    • Van Belle, T.L.1    Nierkens, S.2    Arens, R.3    Von Herrath, M.G.4
  • 92
    • 0028501432 scopus 로고
    • Islet expression of interferon-α precedes diabetes in both the BB rat and streptozotocin-treated mice
    • Huang, X., Hultgren, B., Dybdal, N. & Stewart, T. A. Islet expression of interferon-α precedes diabetes in both the BB rat and streptozotocin-treated mice. Immunity 1, 469-478 (1994).
    • (1994) Immunity , vol.1 , pp. 469-478
    • Huang, X.1    Hultgren, B.2    Dybdal, N.3    Stewart, T.A.4
  • 93
    • 0029036567 scopus 로고
    • Interferon expression in the pancreases of patients with type i diabetes
    • Huang, X. et al. Interferon expression in the pancreases of patients with type I diabetes. Diabetes 44, 658-664 (1995).
    • (1995) Diabetes , vol.44 , pp. 658-664
    • Huang, X.1
  • 94
    • 50449087345 scopus 로고    scopus 로고
    • Interferon-α initiates type 1 diabetes in nonobese diabetic mice
    • Li, Q. et al. Interferon-α initiates type 1 diabetes in nonobese diabetic mice. Proc. Natl Acad. Sci. USA 105, 12439-12444 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 12439-12444
    • Li, Q.1
  • 95
    • 84872053925 scopus 로고    scopus 로고
    • Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
    • Diana, J. et al. Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes. Nature Med. 19, 65-73 (2013).
    • (2013) Nature Med , vol.19 , pp. 65-73
    • Diana, J.1
  • 96
    • 63249126027 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture
    • Allen, J. S. et al. Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture. Diabetes 58, 138-145 (2009).
    • (2009) Diabetes , vol.58 , pp. 138-145
    • Allen, J.S.1
  • 98
    • 14944346879 scopus 로고    scopus 로고
    • Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development
    • O'Keeffe, M. et al. Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development. Int. Immunol. 17, 307-314 (2005).
    • (2005) Int. Immunol , vol.17 , pp. 307-314
    • O'keeffe, M.1
  • 99
    • 12144270876 scopus 로고    scopus 로고
    • + regulatory T-cells
    • DOI 10.2337/diabetes.54.1.78
    • Kared, H. et al. Treatment with granulocyte colony-stimulating factor prevents diabetes in NOD mice by recruiting plasmacytoid dendritic cells and functional CD4+CD25+ regulatory T-cells. Diabetes 54, 78-84 (2005). (Pubitemid 40105097)
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 78-84
    • Kared, H.1    Masson, A.2    Adle-Biassette, H.3    Bach, J.-F.4    Chatenoud, L.5    Zavala, F.6
  • 100
    • 84857195764 scopus 로고    scopus 로고
    • Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet β-cells
    • Grupillo, M. et al. Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet β-cells. Cell. Immunol. 273, 115-123 (2012).
    • (2012) Cell. Immunol , vol.273 , pp. 115-123
    • Grupillo, M.1
  • 101
    • 84867033893 scopus 로고    scopus 로고
    • Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity
    • Walsh, E. R. et al. Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity. Proc. Natl Acad. Sci. USA 109, 16276-16281 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 16276-16281
    • Walsh, E.R.1
  • 103
    • 0037451124 scopus 로고    scopus 로고
    • Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice
    • Santiago-Raber, M. L. et al. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. J. Exp. Med. 197, 777-788 (2003).
    • (2003) J. Exp. Med , vol.197 , pp. 777-788
    • Santiago-Raber, M.L.1
  • 104
    • 36949003890 scopus 로고    scopus 로고
    • 1 mice
    • DOI 10.1038/sj.gene.6364430, PII 6364430
    • Jorgensen, T. N., Roper, E., Thurman, J. M., Marrack, P. & Kotzin, B. L. Type I interferon signaling is involved in the spontaneous development of lupus-like disease in B6.Nba2 and (B6.Nba2 x NZW)F(1) mice. Genes Immun. 8, 653-662 (2007). (Pubitemid 350238435)
    • (2007) Genes and Immunity , vol.8 , Issue.8 , pp. 653-662
    • Jorgensen, T.N.1    Roper, E.2    Thurman, J.M.3    Marrack, P.4    Kotzin, B.L.5
  • 105
    • 0035905409 scopus 로고    scopus 로고
    • A pivotal role for the natural interferon α-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus
    • Ronnblom, L. & Alm, G. V. A pivotal role for the natural interferon-α-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus. J. Exp. Med. 194, F59-F63 (2001). (Pubitemid 34028649)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.12
    • Ronnblom, L.1    Alm, G.V.2
  • 106
    • 0034913451 scopus 로고    scopus 로고
    • Presence of cutaneous interferon-α producing cells in patients with systemic lupus erythematosus
    • DOI 10.1191/096120301678416042
    • Blomberg, S. et al. Presence of cutaneous interferon-α producing cells in patients with systemic lupus erythematosus. Lupus 10, 484-490 (2001). (Pubitemid 32675048)
    • (2001) Lupus , vol.10 , Issue.7 , pp. 484-490
    • Blomberg, S.1    Eloranta, M.L.2    Cederblad, B.3    Nordlind, K.4    Alm, G.V.5    Ronnblom, L.6
  • 107
    • 0041832267 scopus 로고    scopus 로고
    • FcγRIIa is expressed on natural IFN-α-producing cells (plasmacytoid dendritic cells) and is required for the IFN-α production induced by apoptotic cells combined with Lupus IgG
    • Bave, U. et al. Fcγ RIIa is expressed on natural IFN-α-producing cells (plasmacytoid dendritic cells) and is required for the IFN-α production induced by apoptotic cells combined with lupus IgG. J. Immunol. 171, 3296-3302 (2003). (Pubitemid 37093557)
    • (2003) Journal of Immunology , vol.171 , Issue.6 , pp. 3296-3302
    • Bave, U.1    Magnusson, M.2    Eloranta, M.-L.3    Perers, A.4    Alm, G.V.5    Ronnblom, L.6
  • 110
    • 79952468782 scopus 로고    scopus 로고
    • Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus
    • Lande, R. et al. Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Sci. Transl. Med. 3, 73ra19 (2011).
    • (2011) Sci. Transl. Med , vol.3
    • Lande, R.1
  • 111
    • 79952476762 scopus 로고    scopus 로고
    • Netting neutrophils are major inducers of type i IFN production in pediatric systemic lupus erythematosus. Sci. Transl
    • Garcia-Romo, G. S. et al. Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci. Transl. Med. 3, 73ra20 (2011). References 110 and 111 provide evidence that pDC activation by neutrophil-derived self-DNA molecules promotes the development of SLE in humans.
    • (2011) Med , vol.3
    • Garcia-Romo, G.S.1
  • 112
    • 77953723966 scopus 로고    scopus 로고
    • TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus
    • Guiducci, C. et al. TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus. Nature 465, 937-941 (2010).
    • (2010) Nature , vol.465 , pp. 937-941
    • Guiducci, C.1
  • 113
    • 78149306478 scopus 로고    scopus 로고
    • Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid predendritic cells (pDCs)
    • Lepelletier, Y. et al. Toll-like receptor control of glucocorticoid- induced apoptosis in human plasmacytoid predendritic cells (pDCs). Blood 116, 3389-3397 (2010).
    • (2010) Blood , vol.116 , pp. 3389-3397
    • Lepelletier, Y.1
  • 114
    • 84871403211 scopus 로고    scopus 로고
    • PU.1 is essential for CD11c expression in CD8+/CD8- lymphoid and monocyte-derived dendritic cells during GM-CSF or FLT3L-induced differentiation
    • Zhu, X. J., Yang, Z. F., Chen, Y., Wang, J. & Rosmarin, A. G. PU.1 is essential for CD11c expression in CD8+/CD8- lymphoid and monocyte-derived dendritic cells during GM-CSF or FLT3L-induced differentiation. PLoS ONE 7, e52141 (2013).
    • (2013) PLoS ONE , vol.7
    • Zhu, X.J.1    Yang, Z.F.2    Chen, Y.3    Wang, J.4    Rosmarin, A.G.5
  • 115
    • 34447275920 scopus 로고    scopus 로고
    • - dendritic cells in the spleen
    • DOI 10.1084/jem.20062648
    • Caton, M. L., Smith-Raska, M. R. & Reizis, B. Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen. J. Exp. Med. 204, 1653-1664 (2007). (Pubitemid 47048031)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.7 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 116
    • 84878167904 scopus 로고    scopus 로고
    • IRF4 transcription-factor-dependent CD103+CD11b+ dendritic cells drive mucosal T helper 17 cell differentiation
    • Persson, E. K. et al. IRF4 transcription-factor-dependent CD103+CD11b+ dendritic cells drive mucosal T helper 17 cell differentiation. Immunity 38, 958-969 (2013).
    • (2013) Immunity , vol.38 , pp. 958-969
    • Persson, E.K.1
  • 117
    • 84878191150 scopus 로고    scopus 로고
    • IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses
    • Schlitzer, A. et al. IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity 38, 970-983 (2013).
    • (2013) Immunity , vol.38 , pp. 970-983
    • Schlitzer, A.1
  • 118
    • 84879547366 scopus 로고    scopus 로고
    • Langerinneg conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice
    • Wohn, C. et al. Langerinneg conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice. Proc. Natl Acad. Sci. USA 110, 10723-10728 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 10723-10728
    • Wohn, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.