-
1
-
-
63349109137
-
Differentiation, expansion, and homeostasis of autoreactive T cells in type 1 diabetes mellitus
-
Monti, P., A. K. Heninger, and E. Bonifacio. 2009. Differentiation, expansion, and homeostasis of autoreactive T cells in type 1 diabetes mellitus. Curr. Diab. Rep. 9: 113-118.
-
(2009)
Curr. Diab. Rep.
, vol.9
, pp. 113-118
-
-
Monti, P.1
Heninger, A.K.2
Bonifacio, E.3
-
2
-
-
33847629171
-
Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes
-
Di Lorenzo, T. P., M. Peakman, and B. O. Roep. 2007. Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes. Clin. Exp. Immunol. 148: 1-16.
-
(2007)
Clin. Exp. Immunol.
, vol.148
, pp. 1-16
-
-
Di Lorenzo, T.P.1
Peakman, M.2
Roep, B.O.3
-
3
-
-
77949889458
-
Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens
-
Honeyman, M. C., N. L. Stone, B. A. Falk, G. Nepom, and L. C. Harrison. 2010. Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens. J. Immunol. 184: 2204-2210.
-
(2010)
J. Immunol.
, vol.184
, pp. 2204-2210
-
-
Honeyman, M.C.1
Stone, N.L.2
Falk, B.A.3
Nepom, G.4
Harrison, L.C.5
-
5
-
-
4344665860
-
Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules
-
DOI 10.2337/diabetes.53.9.2330
-
Chimienti, F., S. Devergnas, A. Favier, and M. Seve. 2004. Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules. Diabetes 53: 2330-2337. (Pubitemid 39145586)
-
(2004)
Diabetes
, vol.53
, Issue.9
, pp. 2330-2337
-
-
Chimienti, F.1
Devergnas, S.2
Favier, A.3
Seve, M.4
-
6
-
-
36749011882
-
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes
-
Wenzlau, J. M., K. Juhl, L. Yu, O. Moua, S. A. Sarkar, P. Gottlieb, M. Rewers, G. S. Eisenbarth, J. Jensen, H. W. Davidson, and J. C. Hutton. 2007. The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc. Natl. Acad. Sci. USA 104: 17040-17045.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 17040-17045
-
-
Wenzlau, J.M.1
Juhl, K.2
Yu, L.3
Moua, O.4
Sarkar, S.A.5
Gottlieb, P.6
Rewers, M.7
Eisenbarth, G.S.8
Jensen, J.9
Davidson, H.W.10
Hutton, J.C.11
-
7
-
-
68449094246
-
Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk
-
Achenbach, P., V. Lampasona, U. Landherr, K. Koczwara, S. Krause, H. Grallert, C. Winkler, M. Pflüger, T. Illig, E. Bonifacio, and A. G. Ziegler. 2009. Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk. Diabetologia 52: 1881-1888.
-
(2009)
Diabetologia
, vol.52
, pp. 1881-1888
-
-
Achenbach, P.1
Lampasona, V.2
Landherr, U.3
Koczwara, K.4
Krause, S.5
Grallert, H.6
Winkler, C.7
Pflüger, M.8
Illig, T.9
Bonifacio, E.10
Ziegler, A.G.11
-
8
-
-
55649122280
-
Association between anti-ZnT8 autoantibody specificities and SLC30A8 Arg325Trp variant in Japanese patients with type 1 diabetes
-
Kawasaki, E., M. Uga, K. Nakamura, G. Kuriya, T. Satoh, K. Fujishima, M. Ozaki, N. Abiru, H. Yamasaki, J. M. Wenzlau, et al. 2008. Association between anti-ZnT8 autoantibody specificities and SLC30A8 Arg325Trp variant in Japanese patients with type 1 diabetes. Diabetologia 51: 2299-2302.
-
(2008)
Diabetologia
, vol.51
, pp. 2299-2302
-
-
Kawasaki, E.1
Uga, M.2
Nakamura, K.3
Kuriya, G.4
Satoh, T.5
Fujishima, K.6
Ozaki, M.7
Abiru, N.8
Yamasaki, H.9
Wenzlau, J.M.10
-
9
-
-
74249087709
-
Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes: Non Insulin Requiring Autoimmune Diabetes (NIRAD) 4
-
Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study Group
-
Lampasona, V., A. Petrone, C. Tiberti, M. Capizzi, M. Spoletini, S. di Pietro, M. Songini, S. Bonicchio, F. Giorgino, E. Bonifacio, et al; Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study Group. 2010. Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes: Non Insulin Requiring Autoimmune Diabetes (NIRAD) 4. Diabetes Care 33: 104-108.
-
(2010)
Diabetes Care
, vol.33
, pp. 104-108
-
-
Lampasona, V.1
Petrone, A.2
Tiberti, C.3
Capizzi, M.4
Spoletini, M.5
Di Pietro, S.6
Songini, M.7
Bonicchio, S.8
Giorgino, F.9
Bonifacio, E.10
-
10
-
-
77949273351
-
Predictive power of screening for antibodies against insulinoma- associated protein 2 beta (IA-2beta) and zinc transporter-8 to select first-degree relatives of type 1 diabetic patients with risk of rapid progression to clinical onset of the disease: Implications for prevention trials
-
Belgian Diabetes Registry.
-
De Grijse, J., M. Asanghanwa, B. Nouthe, N. Albrecher, P. Goubert, I. Vermeulen, S. Van Der Meeren, K. Decochez, I. Weets, B. Keymeulen, et al; Belgian Diabetes Registry. 2010. Predictive power of screening for antibodies against insulinoma-associated protein 2 beta (IA-2beta) and zinc transporter-8 to select first-degree relatives of type 1 diabetic patients with risk of rapid progression to clinical onset of the disease: implications for prevention trials. Diabetologia 53: 517-524.
-
(2010)
Diabetologia
, vol.53
, pp. 517-524
-
-
De Grijse, J.1
Asanghanwa, M.2
Nouthe, B.3
Albrecher, N.4
Goubert, P.5
Vermeulen, I.6
Van Der Meeren, S.7
Decochez, K.8
Weets, I.9
Keymeulen, B.10
-
11
-
-
0030175582
-
Relation between cellular and humoral immunity to islet cell antigens in type 1 diabetes
-
Hummel, M., I. Durinovic-Bello, and A. G. Ziegler. 1996. Relation between cellular and humoral immunity to islet cell antigens in type 1 diabetes. J. Autoimmun. 9: 427-430.
-
(1996)
J. Autoimmun.
, vol.9
, pp. 427-430
-
-
Hummel, M.1
Durinovic-Bello, I.2
Ziegler, A.G.3
-
12
-
-
70350534475
-
Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes
-
Type 1 Diabetes TrialNet Research Group
-
Herold, K. C., B. Brooks-Worrell, J. Palmer, H. M. Dosch, M. Peakman, P. Gottlieb, H. Reijonen, S. Arif, L. M. Spain, C. Thompson, J. M. Lachin; Type 1 Diabetes TrialNet Research Group. 2009. Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes. Diabetes 58: 2588-2595.
-
(2009)
Diabetes
, vol.58
, pp. 2588-2595
-
-
Herold, K.C.1
Brooks-Worrell, B.2
Palmer, J.3
Dosch, H.M.4
Peakman, M.5
Gottlieb, P.6
Reijonen, H.7
Arif, S.8
Spain, L.M.9
Thompson, C.10
Lachin, J.M.11
-
13
-
-
14544301525
-
Detection of autoreactive T cells in type 1 diabetes using coded autoantigens and an immunoglobulin-free cytokine ELISPOT assay: Report from the fourth immunology of diabetes society T cell workshop
-
Nagata, M., R. Kotani, H. Moriyama, K. Yokono, B. O. Roep, and M. Peakman. 2004. Detection of autoreactive T cells in type 1 diabetes using coded autoantigens and an immunoglobulin-free cytokine ELISPOT assay: report from the fourth immunology of diabetes society T cell workshop. Ann. N. Y. Acad. Sci. 1037: 10-15.
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1037
, pp. 10-15
-
-
Nagata, M.1
Kotani, R.2
Moriyama, H.3
Yokono, K.4
Roep, B.O.5
Peakman, M.6
-
14
-
-
85047690395
-
Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health
-
Arif, S., T. I. Tree, T. P. Astill, J. M. Tremble, A. J. Bishop, C. M. Dayan, B. O. Roep, and M. Peakman. 2004. Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health. J. Clin. Invest. 113: 451-463.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 451-463
-
-
Arif, S.1
Tree, T.I.2
Astill, T.P.3
Tremble, J.M.4
Bishop, A.J.5
Dayan, C.M.6
Roep, B.O.7
Peakman, M.8
-
15
-
-
0028799010
-
ICA512 autoantibody radioassay
-
Gianani, R., D. U. Rabin, C. F. Verge, L. Yu, S. R. Babu, M. Pietropaolo, and G. S. Eisenbarth. 1995. ICA512 autoantibody radioassay. Diabetes 44: 1340-1344.
-
(1995)
Diabetes
, vol.44
, pp. 1340-1344
-
-
Gianani, R.1
Rabin, D.U.2
Verge, C.F.3
Yu, L.4
Babu, S.R.5
Pietropaolo, M.6
Eisenbarth, G.S.7
-
16
-
-
0028820248
-
Radioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands
-
Falorni, A., E. Ortqvist, B. Persson, and A. Lernmark. 1995. Radioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands. J. Immunol. Methods 186: 89-99.
-
(1995)
J. Immunol. Methods
, vol.186
, pp. 89-99
-
-
Falorni, A.1
Ortqvist, E.2
Persson, B.3
Lernmark, A.4
-
17
-
-
0034652317
-
Early expression of antiinsulin autoantibodies of humans and the NOD mouse: Evidence for early determination of subsequent diabetes
-
Yu, L., D. T. Robles, N. Abiru, P. Kaur, M. Rewers, K. Kelemen, and G. S. Eisenbarth. 2000. Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes. Proc. Natl. Acad. Sci. USA 97: 1701-1706.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1701-1706
-
-
Yu, L.1
Robles, D.T.2
Abiru, N.3
Kaur, P.4
Rewers, M.5
Kelemen, K.6
Eisenbarth, G.S.7
-
18
-
-
0035026043
-
HLA DNA typing and transplantation
-
DOI 10.1016/S1074-7613(01)00115-7
-
Erlich, H. A., G. Opelz, and J. Hansen. 2001. HLA DNA typing and transplantation. Immunity 14: 347-356. (Pubitemid 32441587)
-
(2001)
Immunity
, vol.14
, Issue.4
, pp. 347-356
-
-
Erlich, H.A.1
Opelz, G.2
Hansen, J.3
-
19
-
-
0027298481
-
HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation
-
Kwok, W. W., S. Kovats, P. Thurtle, and G. T. Nepom. 1993. HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation. J. Immunol. 150: 2263-2272.
-
(1993)
J. Immunol.
, vol.150
, pp. 2263-2272
-
-
Kwok, W.W.1
Kovats, S.2
Thurtle, P.3
Nepom, G.T.4
-
20
-
-
65049083839
-
Improved T cell assay for identification of type 1 diabetes patients
-
Brooks-Worrell, B., A. Warsen, and J. P. Palmer. 2009. Improved T cell assay for identification of type 1 diabetes patients. J. Immunol. Methods 344: 79-83.
-
(2009)
J. Immunol. Methods
, vol.344
, pp. 79-83
-
-
Brooks-Worrell, B.1
Warsen, A.2
Palmer, J.P.3
-
21
-
-
0030589224
-
Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins
-
Brooks-Worrell, B. M., G. A. Starkebaum, C. Greenbaum, and J. P. Palmer. 1996. Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins. J. Immunol. 157: 5668-5674.
-
(1996)
J. Immunol.
, vol.157
, pp. 5668-5674
-
-
Brooks-Worrell, B.M.1
Starkebaum, G.A.2
Greenbaum, C.3
Palmer, J.P.4
-
22
-
-
33845775174
-
Genetic determinants of type 1 diabetes across populations
-
Jahromi, M. M., and G. S. Eisenbarth. 2006. Genetic determinants of type 1 diabetes across populations. Ann. N. Y. Acad. Sci. 1079: 289-299.
-
(2006)
Ann. N. Y. Acad. Sci.
, vol.1079
, pp. 289-299
-
-
Jahromi, M.M.1
Eisenbarth, G.S.2
-
23
-
-
0025131118
-
A unified hypothesis for the complex genetics of HLA associations with IDDM
-
Nepom, G. T. 1990. A unified hypothesis for the complex genetics of HLA associations with IDDM. Diabetes 39: 1153-1157. (Pubitemid 20327048)
-
(1990)
Diabetes
, vol.39
, Issue.10
, pp. 1153-1157
-
-
Nepom, G.T.1
-
24
-
-
0026500805
-
HLA and insulin-dependent diabetes. A protective perspective
-
Sheehy, M. J. 1992. HLA and insulin-dependent diabetes. A protective perspective. Diabetes 41: 123-129.
-
(1992)
Diabetes
, vol.41
, pp. 123-129
-
-
Sheehy, M.J.1
-
25
-
-
0035554904
-
Sex differences in autoimmune disease
-
Whitacre, C. C. 2001. Sex differences in autoimmune disease. Nat. Immunol. 2: 777-780.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 777-780
-
-
Whitacre, C.C.1
-
26
-
-
0037216057
-
Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes
-
Narendran, P., A. J. Williams, K. Elsegood, N. J. Leech, and C. M. Dayan. 2003. Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes. Diabetes Metab. Res. Rev. 19: 52-59.
-
(2003)
Diabetes Metab. Res. Rev.
, vol.19
, pp. 52-59
-
-
Narendran, P.1
Williams, A.J.2
Elsegood, K.3
Leech, N.J.4
Dayan, C.M.5
-
27
-
-
0035554935
-
Separable effector T cell populations specialized for B cell help or tissue inflammation
-
Campbell, D. J., C. H. Kim, and E. C. Butcher. 2001. Separable effector T cell populations specialized for B cell help or tissue inflammation. Nat. Immunol. 2: 876-881.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 876-881
-
-
Campbell, D.J.1
Kim, C.H.2
Butcher, E.C.3
-
28
-
-
0034005833
-
T-cell lines reactive to an immunodominant epitope of the tyrosine phosphatase-like autoantigen IA-2 in type 1 diabetes
-
Hawkes, C. J., N. C. Schloot, J. Marks, S. J. Willemen, J. W. Drijfhout, E. K. Mayer, M. R. Christie, and B. O. Roep. 2000. T-cell lines reactive to an immunodominant epitope of the tyrosine phosphatase-like autoantigen IA-2 in type 1 diabetes. Diabetes 49: 356-366.
-
(2000)
Diabetes
, vol.49
, pp. 356-366
-
-
Hawkes, C.J.1
Schloot, N.C.2
Marks, J.3
Willemen, S.J.4
Drijfhout, J.W.5
Mayer, E.K.6
Christie, M.R.7
Roep, B.O.8
-
29
-
-
0036711007
-
Cytokine detection by ELISPOT: Relevance for immunological studies in type 1 diabetes
-
Meierhoff, G., P. A. Ott, P. V. Lehmann, and N. C. Schloot. 2002. Cytokine detection by ELISPOT: relevance for immunological studies in type 1 diabetes. Diabetes Metab. Res. Rev. 18: 367-380.
-
(2002)
Diabetes Metab. Res. Rev.
, vol.18
, pp. 367-380
-
-
Meierhoff, G.1
Ott, P.A.2
Lehmann, P.V.3
Schloot, N.C.4
-
30
-
-
73349085255
-
b cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct
-
Li, L., Q. He, A. Garland, Z. Yi, L. T. Aybar, T. B. Kepler, J. A. Frelinger, B. Wang, and R. Tisch. 2009. b cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct. J. Immunol. 183: 7585-7591.
-
(2009)
J. Immunol.
, vol.183
, pp. 7585-7591
-
-
Li, L.1
He, Q.2
Garland, A.3
Yi, Z.4
Aybar, L.T.5
Kepler, T.B.6
Frelinger, J.A.7
Wang, B.8
Tisch, R.9
-
31
-
-
33846550244
-
+ T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets
-
Wong, C. P., R. Stevens, B. Long, L. Li, Y. Wang, M. A. Wallet, K. S. Goudy, J. A. Frelinger, and R. Tisch. 2007. Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets. J. Immunol. 178: 1388-1395. (Pubitemid 46154609)
-
(2007)
Journal of Immunology
, vol.178
, Issue.3
, pp. 1388-1395
-
-
Wong, C.P.1
Stevens, R.2
Long, B.3
Li, L.4
Wang, Y.5
Wallet, M.A.6
Goudy, K.S.7
Frelinger, J.A.8
Tisch, R.9
-
34
-
-
56749161528
-
Transcriptional regulation by AIRE: Molecular mechanisms of central tolerance
-
Peterson, P., T. Org, and A. Rebane. 2008. Transcriptional regulation by AIRE: molecular mechanisms of central tolerance. Nat. Rev. Immunol. 8: 948-957.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 948-957
-
-
Peterson, P.1
Org, T.2
Rebane, A.3
-
35
-
-
69049109653
-
Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes
-
Yip, L., L. Su, D. Sheng, P. Chang, M. Atkinson, M. Czesak, P. R. Albert, A. R. Collier, S. J. Turley, C. G. Fathman, and R. J. Creusot. 2009. Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes. Nat. Immunol. 10: 1026-1033.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1026-1033
-
-
Yip, L.1
Su, L.2
Sheng, D.3
Chang, P.4
Atkinson, M.5
Czesak, M.6
Albert, P.R.7
Collier, A.R.8
Turley, S.J.9
Fathman, C.G.10
Creusot, R.J.11
-
36
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
-
Derbinski, J., J. Gäbler, B. Brors, S. Tierling, S. Jonnakuty, M. Hergenhahn, L. Peltonen, J. Walter, and B. Kyewski. 2005. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J. Exp. Med. 202: 33-45.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
Gäbler, J.2
Brors, B.3
Tierling, S.4
Jonnakuty, S.5
Hergenhahn, M.6
Peltonen, L.7
Walter, J.8
Kyewski, B.9
-
37
-
-
3442880270
-
T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading
-
Ott, P. A., M. T. Dittrich, B. A. Herzog, R. Guerkov, P. A. Gottlieb, A. L. Putnam, I. Durinovic-Bello, B. O. Boehm, M. Tary-Lehmann, and P. V. Lehmann. 2004. T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading. J. Clin. Immunol. 24: 327-339.
-
(2004)
J. Clin. Immunol.
, vol.24
, pp. 327-339
-
-
Ott, P.A.1
Dittrich, M.T.2
Herzog, B.A.3
Guerkov, R.4
Gottlieb, P.A.5
Putnam, A.L.6
Durinovic-Bello, I.7
Boehm, B.O.8
Tary-Lehmann, M.9
Lehmann, P.V.10
-
38
-
-
3242702137
-
- T cells in type 1 diabetic subjects
-
DOI 10.1016/j.jaut.2004.03.009, PII S0896841104000381
-
Herzog, B. A., P. A. Ott, M. T. Dittrich, S. Quast, A. Y. Karulin, H. Kalbacher, W. Karges, M. Tary-Lehmann, P. V. Lehmann, B. O. Boehm, and I. Durinovic-Belló. 2004. Increased in vivo frequency of IA-2 peptide-reactive IFNgamma+/IL-4- T cells in type 1 diabetic subjects. J. Autoimmun. 23: 45-54. (Pubitemid 38953792)
-
(2004)
Journal of Autoimmunity
, vol.23
, Issue.1
, pp. 45-54
-
-
Herzog, B.A.1
Ott, P.A.2
Dittrich, M.T.3
Quast, S.4
Karulin, A.Y.5
Kalbacher, H.6
Karges, W.7
Tary-Lehmann, M.8
Lehmann, P.V.9
Boehm, B.O.10
Durinovic-Bello, I.11
|