Dendritic cells, chemokine receptors and autoimmune inflammatory diseases

Immunology and Cell Biology

Volumn 80, Issue 5, 2002, Pages 497-505

  Cravens, P D ^a   Lipsky, P E ^b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

Autoimmune inflammatory lesions; Chemokine receptors; Chemokines; Dendritic cells

Indexed keywords

CHEMOKINE RECEPTOR;

ANTIGEN PRESENTING CELL; AUTOIMMUNE DISEASE; B LYMPHOCYTE; DENDRITIC CELL; DIABETES MELLITUS; HUMAN; IMMUNE SYSTEM; INFLAMMATION; LYMPH NODE; LYMPHOID TISSUE; MOLECULAR WEIGHT; MONOCYTE; MULTIPLE SCLEROSIS; NEUTROPHIL; NONHUMAN; PROTEIN EXPRESSION; PSORIASIS; REVIEW; RHEUMATOID ARTHRITIS; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE;

ADULT; ANTIGEN PRESENTATION; ARTHRITIS, RHEUMATOID; AUTOIMMUNE DISEASES; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINES; CHEMOTAXIS; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; GENE EXPRESSION REGULATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFLAMMATION; INTERLEUKIN-4; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MODELS, IMMUNOLOGICAL; MULTIPLE SCLEROSIS; PSORIASIS; RECEPTORS, CHEMOKINE; SJOGREN'S SYNDROME; T-LYMPHOCYTE SUBSETS;

EID: 0036378060     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.2002.01118.x     Document Type: Review

References (63)

1. Steinman RM. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 1991; 9: 271-96.
2. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245-52.
3. Banchereau J, Briere F, Caux C et al. Immunobiology of dendritic cells. Annu. Rev. 2000; 18: 767-811.
4. Ludewig B, Junt T, Hengartner H, Zinkernagel RM. Dendritic cells in autoimmune diseases. Curr. Opin. Immunol. 2001; 13: 657-62.
5. Foerster R, Schubel A, Breitfeld D et al. CCR7 coordinates the primary immune response by establishing functional micro-environments in secondary lymphoid organs. Cell 1999; 99: 23-33.
6. Sallusto F, Palermo B, Lenig D et al. Distinct patterns and kinetics of chemokine production regulate dendritic cell function. Eur. J. Immunol. 1999; 29: 1617-25.
7. Robbiani DF, Finch RA, Jager D, Muller WA, Sartorelli AC, Randolph GJ. The leukotriene C (4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC) -dependent mobilization of dendritic cells to lymph nodes. Cell 2000; 103: 757-68.
8. Thomas R, Davis LS, Lipsky PE. Rheumatoid synovium is enriched in mature antigen-presenting dendritic cells. J. Immunol. 1994; 152: 2613-23.
9. Nestle FO, Turka LA, Nickoloff BJ. Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines. J. Clin. Invest. 1994; 94: 202-9.
10. Ozaki Y, Amakawa R, Ito T et al. Alteration of peripheral blood dendritic cells in patients with primary Sjogren's syndrome. Arthritis Rheum. 2001; 44: 419-31.
11. Baggiolini M. Chemokines and leukocyte traffic. Nature 1998; 392: 565-8.
12. Rossi D, Zlotnik A (eds.) The Biology of Chemokines and Their Receptors. Annual Reviews 2000; 18: 217-43.
13. Forester R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 1996; 87: 1037-47.
14. Gunn MD, Tangemann K, Tam C, Cyster JG, Rosen SD, Williams LT. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc. Natl. Acad. Sci. USA 1998; 95: 258-63.
15. Gunn MD, Kyuwa S, Tam C et al. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 1999; 189: 451-60.
16. Reif K, Ekland EH, Ohl L et al. Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position. Nature 2002; 416: 94-9.
17. Nanki T, Lipsky PE. Cutting edge: stromal cell-derived factor-1 is a costimulator for CD4+ T cell activation. J. Immunol. 2000; 164: 5010-14.
18. Shi K, Hayashida K, Kaneko M et al. Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis patients. J. Immunol. 2001; 166: 650-5.
19. Amft N, Bowman SJ. Chemokines and cell trafficking in Sjogren's syndrome. Scand. J. Immunol. 2001; 54: 62-9.
20. Oppenheim JJ, Yang D, Biragyn A, Howard OM, Plotz P. Chemokine receptors on dendritic cells promote autoimmune reactions. Arthritis Res. 2002; 4: S183-S188.
21. Armengol MP, Juan M, Lucas-Martin Aet al. Thyroid autoimmune disease: demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers. Am. J. Pathol. 2001; 159: 861-73.
22. Homey BMC, Dieu-Nosjean A, Wiesenborn C et al. Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis. J. Immunol. 2000; 164: 6621-32.
23. Pashenkov M, Teleshova N, Kouwenhoven M et al. Elevated expression of CCR5 by myeloid (CD11c+) blood dendritic cells in multiple sclerosis and acute optic neuritis. Clin. Exp. Immunol. 2002; 127: 519-26.
24. Sozzani S, Luini W, Borsatti A et al. Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. J. Immunol. 1997; 159: 1993-2000.
25. Dieu MC, Vanbervliet B, Vicari A et al. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 1998; 188: 373-86.
26. Sallusto F, Schaerli P, Loetscher P et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur. J. Immunol. 1998; 28: 2760-9.
27. Roake JA, Rao AS, Morris PJ, Larsen CP, Hankins DF, Austyn JM. Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor and Interleukin 1. J. Exp. Med. 1995; 181: 2237-47.
28. Cumberbatch M, Dearman RJ, Antonopoulos C, Groves RW, Kimber I. Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-alpha- and IL-1beta-dependent mechanism. Immunology 2001; 102: 323-30.
29. Kripke ML, Munn CG, Jeevan A, Tang JM, Bucana C. Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J. Immunol. 1990; 145: 2833-8.
30. Randolph GJ, Inaba K, Robbiani DF, Steinman RM, Muller WA. Differentiation of phagocytic monocytes into lymph node dendritic cellsin vivo. Immunity 1999; 11: 753-61.
31. Yanagihara S, Komura E, Nagafune J, Watarai H, Yamaguchi Y. EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation. J. Immunol. 1998; 161: 3096-102.
32. Saeki H, Moore AM, Brown MJ, Hwang ST. Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J. Immunol. 1999; 162: 2472-5.
33. Siegal FP, Kadowaki N, Shodell M et al. The nature of the principal type 1 interferon-producing cells in human blood. Science 1999; 284: 1835-7.
34. Ito T, Inaba M, Inaba K et al. A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells. J. Immunol. 1999; 163: 1409-19.
35. Cella M, Jarrossay D, Facchetti F et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat. Med. 1999; 5: 919-23.
36. Facchetti F, De Wolf-Peeters C, van den Oord JJ, De vos R, Desmet VJ. Plasmacytoid T cells: a cell population normally present in the reactive lymph node. An immunohistochemical and electronmicroscopic study. Hum. Pathol. 1988; 19: 1085-92.
37. Penna G, Sozzani S, Adorini L. Cutting edge: selective usage of chemokine receptors by plasmacytoid dendritic cells. J. Immunol. 2001; 167: 1862-6.
38. Cravens PD. Phenotypic and functional analysis of human peripheral blood dendritic cell precursor populations. In: Department of Internal Medicine. Dallas, TX, USA: University of Texas Southwestern Medical Center, 2001; 248.
39. Charbonnier AS, Kohrgruber N, Kriehuber E, Stingl G, Rot A, Maurer D. Macrophage inflammatory protein 3 alpha is involved in the constitutive trafficking of epidermal langerhans cells. J. Exp. Med. 1999; 190: 1755-68.
40. Nanki T, Hayashida K, El-Gabalawy HS et al. Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4 (+) T cell accumulation in rheumatoid arthritis synovium. J. Immunol. 2000; 165: 6590-8.
41. Pettit AR, MacDonald KP, O'Sullivan B, Thomas R. Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates. Arthritis Rheum. 2000; 43: 791-800.
42. Blades MC, Ingegnoli F, Wheller SK et al. Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice. Arthritis Rheum. 2002; 46: 824-36.
43. Page G, Lebecque S, Miossec P. Anatomic localization of immature and mature dendritic cells in an ectopic lymphoid organ: correlation with selective chemokine expression in rheumatoid synovium. J. Immunol. 2002; 168: 5333-41.
44. Chabaud M, Page G, Miossec P. Enhancing effect of IL-1, IL-17, and TNF-alpha on macrophage inflammatory protein-3alpha production in rheumatoid arthritis: regulation by soluble receptors and Th2 cytokines. J. Immunol. 2001; 167: 6015-20.
45. Winchester RJ (ed.) Arthritis and Allied Conditions. Baltimore, MD: Lippincott Williams & Wilkins, 1997; 1361-91.
46. Lipsky PE. Systemic lupus erythematosus. an autoimmune disease of B cell hyperactivity. Nat. Immunol. 2001; 2: 764-6.
47. Ytterberg SR, Schnitzer TJ. Serum interferon levels in patients with systemic lupus erythematosus. Arthritis Rheum. 1982; 25: 401-6.
48. Vallin H, Blomberg S, Alm GV, Cederblad B, Ronnblom L. Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-alpha) production acting on leucocytes resembling immature dendritic cells. Clin. Exp. Immunol. 1999; 115: 196-202.
49. Ronnblom L, Alm GV. A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus. J. Exp. Med. 2001; 194: F59-63.
50. Cederblad B, Blomberg S, Vallin H, Perers A, Alm GV, Ronnblom L. Patients with systemic lupus erythematosus have reduced numbers of circulating natural interferon-alpha- producing cells. J. Autoimmun. 1998; 11: 465-70.
51. Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 2001; 294: 1540-3.
52. Farkas L, Beiske K, Lund-Johansen F, Brandtzaeg P, Jahnsen FL. Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions. Am. J. Pathol 2001; 159: 237-43.
53. Parlato S, Santini SM, Lapenta C et al. Expression of CCR-7, MIP-3beta, and Th-1 chemokines in type I IFN- induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities. Blood 2001; 98: 3022-9.
54. Green EA, Eynon EE, Flavell RA. Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens. Immunity 1998; 9: 733-43.
55. Dahlen E, Dawe K, Ohlsson L, Hedlund G. Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse. J. Immunol. 1998; 160: 3585-93.
56. Ludewig B, Odermatt B, Landmann S, Hengartner H, Zinkernagel RM. Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue. J. Exp. Med. 1998; 188: 1493-501.
57. Jansen A, Voorbij HA, Jeucken PH, Bruining GJ, Hooijkaas H, Drexhage HA. An immunohistochemical study on organized lymphoid cell infiltrates in fetal and neonatal pancreases. A comparison with similar infiltrates found in the pancreas of a diabetic infant. Autoimmunity 1993; 15: 31-8.
58. Piemonti L, Leone BE, Nano R et al. Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation. Diabetes 2002; 51: 55-65.
59. Traugott U, Reinherz EL, Raine CS. Multiple sclerosis: distribution of T cell subsets within active chronic lesions. Science 1983; 219: 308-10.
60. Pashenkov M, Huang YM, Kostulas V, Haglund M, Soderstrom M, Link H. Brain 2001; 124: 480-92.
61. Sorensen TL, Tani M, Jensen J et al. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J. Clin. Invest. 1999; 103: 807-15.
62. Balashov KE, Rottman JB, Weiner HL, Hancock WW. CCR5 (+) and CXCR3 (+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions. Proc. Natl Acad. Sci. USA 1999; 96: 6873-8.
63. Bennetts BH, Teutsch SM, Buhler MM, Heard RN, Stewart GJ. The CCR5 deletion mutation fails to protect against multiple sclerosis. Hum. Immunol. 1997; 58: 52-9.