-
1
-
-
0020596551
-
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)
-
(doi:10.1126/science. 6189183)
-
Barre-Sinoussi F et al. 1983 Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 220, 868-871. (doi:10.1126/science. 6189183)
-
(1983)
Science
, vol.220
, pp. 868-871
-
-
Barre-Sinoussi, F.1
-
2
-
-
84864345953
-
Towards an HIV cure: A global scientific strategy
-
(doi:10.1038/nri3262)
-
Deeks SG et al. 2012 Towards an HIV cure: a global scientific strategy. Nat. Rev. Immunol. 12, 607-614. (doi:10.1038/nri3262)
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 607-614
-
-
Deeks, S.G.1
-
3
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
-
(doi:10.1056/ NEJMoa0802905)
-
Hutter G et al. 2009 Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N. Engl. J. Med. 360, 692-698. (doi:10.1056/ NEJMoa0802905)
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 692-698
-
-
Hutter, G.1
-
4
-
-
79953117041
-
Evidence for the cure of HIV infection by CCR5D32/D32 stem cell transplantation
-
(doi:10. 1182/blood-2010-09-309591)
-
Allers K, Hutter G, Hofmann J, Loddenkemper C, Rieger K, Thiel E, Schneider T. 2011 Evidence for the cure of HIV infection by CCR5D32/D32 stem cell transplantation. Blood 117, 2791-2799. (doi:10. 1182/blood-2010-09-309591)
-
(2011)
Blood
, vol.117
, pp. 2791-2799
-
-
Allers, K.1
Hutter, G.2
Hofmann, J.3
Loddenkemper, C.4
Rieger, K.5
Thiel, E.6
Schneider, T.7
-
5
-
-
84878503062
-
Challenges in detecting HIV persistence during potentially curative interventions: A study of the Berlin patient
-
(doi:10.1371/journal.ppat.1003347)
-
Yukl SA et al. 2013 Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog. 9, e1003347. (doi:10.1371/journal.ppat.1003347)
-
(2013)
PLoS Pathog.
, vol.9
-
-
Yukl, S.A.1
-
6
-
-
84879320681
-
HIV controllers: A genetically determined or inducible phenotype?
-
(doi:10.1111/imr. 12076)
-
Saez-Cirion A, Pancino G. 2013 HIV controllers: a genetically determined or inducible phenotype? Immunol. Rev. 254, 281-294. (doi:10.1111/imr. 12076)
-
(2013)
Immunol. Rev.
, vol.254
, pp. 281-294
-
-
Saez-Cirion, A.1
Pancino, G.2
-
7
-
-
0030070991
-
Prognosis in HIV-1 infection predicted by the quantity of virus in plasma
-
(doi:10.1126/science.272. 5265.1167)
-
Mellors JW, Rinaldo Jr CR, Gupta P, White RM, Todd JA, Kingsley LA. 1996 Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science 272, 1167-1170. (doi:10.1126/science.272. 5265.1167)
-
(1996)
Science
, vol.272
, pp. 1167-1170
-
-
Mellors, J.W.1
Rinaldo Jr., C.R.2
Gupta, P.3
White, R.M.4
Todd, J.A.5
Kingsley, L.A.6
-
8
-
-
0032955651
-
Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage
-
(doi:10.1086/314660)
-
Giorgi JV et al. 1999 Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J. Infect. Dis. 179, 859-870. (doi:10.1086/314660)
-
(1999)
J. Infect. Dis.
, vol.179
, pp. 859-870
-
-
Giorgi, J.V.1
-
9
-
-
0037105617
-
CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load
-
Sousa AE, Carneiro J, Meier-Schellersheim M, Grossman Z, Victorino RM. 2002 CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load. J. Immunol. 169, 3400-3406.
-
(2002)
J. Immunol.
, vol.169
, pp. 3400-3406
-
-
Sousa, A.E.1
Carneiro, J.2
Meier-Schellersheim, M.3
Grossman, Z.4
Victorino, R.M.5
-
10
-
-
0041327667
-
Persistent immune activation in HIV-1 infection is associated with progression to AIDS
-
(doi:10.1097/ 00002030-200309050-00006)
-
Hazenberg MD, Otto SA, van Benthem BH, Roos MT, Coutinho RA, Lange JM, Hamann D, Prins M, Miedema F. 2003 Persistent immune activation in HIV-1 infection is associated with progression to AIDS. AIDS 17, 1881-1888. (doi:10.1097/ 00002030-200309050-00006)
-
(2003)
AIDS
, vol.17
, pp. 1881-1888
-
-
Hazenberg, M.D.1
Otto, S.A.2
van Benthem, B.H.3
Roos, M.T.4
Coutinho, R.A.5
Lange, J.M.6
Hamann, D.7
Prins, M.8
Miedema, F.9
-
11
-
-
55949084601
-
Inflammatory and coagulation biomarkers and mortality in patients with HIV infection
-
(doi:10.1371/journal. pmed.0050203)
-
Kuller LH et al. 2008 Inflammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Med. 5, e203. (doi:10.1371/journal. pmed.0050203)
-
(2008)
PLoS Med.
, vol.5
-
-
Kuller, L.H.1
-
12
-
-
84879295275
-
HIV-associated chronic immune activation
-
(doi:10.1111/imr.12079)
-
Paiardini M, Müller-Trutwin M. 2013 HIV-associated chronic immune activation. Immunol. Rev. 254, 78-101. (doi:10.1111/imr.12079)
-
(2013)
Immunol. Rev.
, vol.254
, pp. 78-101
-
-
Paiardini, M.1
Müller-Trutwin, M.2
-
13
-
-
84866978487
-
Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection
-
(doi:10.1371/journal.pone.0046143)
-
Liovat AS et al. 2012 Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection. PLoS ONE 7, e46143. (doi:10.1371/journal.pone.0046143)
-
(2012)
PLoS ONE
, vol.7
-
-
Liovat, A.S.1
-
14
-
-
0242410967
-
Differential induction of TGF-beta regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections
-
Omer FM, de Souza JB, Riley EM. 2003 Differential induction of TGF-beta regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections. J. Immunol. 171, 5430-5436.
-
(2003)
J. Immunol.
, vol.171
, pp. 5430-5436
-
-
Omer, F.M.1
de Souza, J.B.2
Riley, E.M.3
-
15
-
-
53349143044
-
Persistent virus infection inhibits type I interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections
-
(doi:10.1016/j.chom.2008.08.016)
-
Zuniga EI, Liou LY, Mack L, Mendoza M, Oldstone MB. 2008 Persistent virus infection inhibits type I interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections. Cell Host Microbe 4, 374-386. (doi:10.1016/j.chom.2008.08.016)
-
(2008)
Cell Host Microbe
, vol.4
, pp. 374-386
-
-
Zuniga, E.I.1
Liou, L.Y.2
Mack, L.3
Mendoza, M.4
Oldstone, M.B.5
-
16
-
-
84892372311
-
Can early therapy reduce inflammation?
-
(doi:10.1097/COH.0000000000000020)
-
Sandler NG, Sereti I. 2014 Can early therapy reduce inflammation? Curr. Opin. HIV AIDS 9, 72-79. (doi:10.1097/COH.0000000000000020)
-
(2014)
Curr. Opin. HIV AIDS
, vol.9
, pp. 72-79
-
-
Sandler, N.G.1
Sereti, I.2
-
17
-
-
84875985311
-
Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI study
-
(doi:10.1371/journal.ppat.1003211)
-
Saez-Cirion A et al. 2013 Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI study. PLoS Pathog. 9, e1003211. (doi:10.1371/journal.ppat.1003211)
-
(2013)
PLoS Pathog.
, vol.9
-
-
Saez-Cirion, A.1
-
18
-
-
77953916829
-
Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection
-
(doi:10.1097/QAD.0b013e32833b61ba)
-
Hocqueloux L, Prazuck T, Avettand-Fenoel V, Lafeuillade A, Cardon B, Viard JP, Rouzioux C. 2010 Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection. AIDS 24, 1598-1601. (doi:10.1097/QAD.0b013e32833b61ba)
-
(2010)
AIDS
, vol.24
, pp. 1598-1601
-
-
Hocqueloux, L.1
Prazuck, T.2
Avettand-Fenoel, V.3
Lafeuillade, A.4
Cardon, B.5
Viard, J.P.6
Rouzioux, C.7
-
19
-
-
84866130614
-
Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion
-
(doi:10.1001/ archinternmed.2012.2719)
-
Lodi S, Meyer L, Kelleher AD, Rosinska M, Ghosn J, Sannes M, Porter K. 2012 Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion. Arch. Intern. Med. 172, 1252-1255. (doi:10.1001/ archinternmed.2012.2719)
-
(2012)
Arch. Intern. Med.
, vol.172
, pp. 1252-1255
-
-
Lodi, S.1
Meyer, L.2
Kelleher, A.D.3
Rosinska, M.4
Ghosn, J.5
Sannes, M.6
Porter, K.7
-
20
-
-
84866735012
-
Continuous versus intermittent treatment strategies during primary HIV-1 infection: The randomized ANRS INTERPRIM trial
-
(doi:10.1097/QAD. 0b013e32835844d9)
-
Goujard C et al. 2012 Continuous versus intermittent treatment strategies during primary HIV-1 infection: the randomized ANRS INTERPRIM trial. AIDS 26, 1895-1905. (doi:10.1097/QAD. 0b013e32835844d9)
-
(2012)
AIDS
, vol.26
, pp. 1895-1905
-
-
Goujard, C.1
-
21
-
-
17644385926
-
Undetectable viremia without antiretroviral therapy in patients with HIV seroconversion: An uncommon phenomenon?
-
(doi:10.1086/429318)
-
Madec Y, Boufassa F, Rouzioux C, Delfraissy JF, Meyer L. 2005 Undetectable viremia without antiretroviral therapy in patients with HIV seroconversion: an uncommon phenomenon? Clin. Infect. Dis. 40, 1350-1354. (doi:10.1086/429318)
-
(2005)
Clin. Infect. Dis.
, vol.40
, pp. 1350-1354
-
-
Madec, Y.1
Boufassa, F.2
Rouzioux, C.3
Delfraissy, J.F.4
Meyer, L.5
-
22
-
-
70049106041
-
Spontaneous control of viral replication during primary HIV infection: When is 'HIV controller' status established?
-
(doi:10.1086/605504)
-
Goujard C et al. 2009 Spontaneous control of viral replication during primary HIV infection: when is 'HIV controller' status established? Clin. Infect. Dis. 49, 982-986. (doi:10.1086/605504)
-
(2009)
Clin. Infect. Dis.
, vol.49
, pp. 982-986
-
-
Goujard, C.1
-
23
-
-
84861606706
-
Immune and viral correlates of 'secondary viral control' after treatment interruption in chronically HIV-1 infected patients
-
(doi:10.1371/journal.pone.0037792)
-
Van Gulck E, Bracke L, Heyndrickx L, Coppens S, Atkinson D, Merlin C, Pasternak A, Florence E, Vanham G. 2012 Immune and viral correlates of 'secondary viral control' after treatment interruption in chronically HIV-1 infected patients. PLoS ONE 7, e37792. (doi:10.1371/journal.pone.0037792)
-
(2012)
PLoS ONE
, vol.7
-
-
Van Gulck, E.1
Bracke, L.2
Heyndrickx, L.3
Coppens, S.4
Atkinson, D.5
Merlin, C.6
Pasternak, A.7
Florence, E.8
Vanham, G.9
-
24
-
-
33751515147
-
+ count-guided interruption of antiretroviral treatment
-
(doi:10.1056/ NEJMoa062360)
-
+ count-guided interruption of antiretroviral treatment. N. Engl. J. Med. 355, 2283-2296. (doi:10.1056/ NEJMoa062360)
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 2283-2296
-
-
El-Sadr, W.M.1
-
25
-
-
0027043276
-
Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
-
(doi:10.1126/science.1470917)
-
Daniel MD, Kirchhoff F, Czajak SC, Sehgal PK, Desrosiers RC. 1992 Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258, 1938-1941. (doi:10.1126/science.1470917)
-
(1992)
Science
, vol.258
, pp. 1938-1941
-
-
Daniel, M.D.1
Kirchhoff, F.2
Czajak, S.C.3
Sehgal, P.K.4
Desrosiers, R.C.5
-
26
-
-
33745070227
-
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1
-
(doi:10.1016/j.cell.2006.04.033)
-
Schindler M et al. 2006 Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell 125, 1055-1067. (doi:10.1016/j.cell.2006.04.033)
-
(2006)
Cell
, vol.125
, pp. 1055-1067
-
-
Schindler, M.1
-
27
-
-
17844376742
-
+ T cells
-
(doi:10. 1038/nature03513)
-
+ T cells. Nature 434, 1148-1152. (doi:10. 1038/nature03513)
-
(2005)
Nature
, vol.434
, pp. 1148-1152
-
-
Li, Q.1
-
29
-
-
9244220630
-
+ memory T cells in rapidly progressive simian immunodeficiency virus infection
-
(doi:10. 1084/jem.20041049)
-
+ memory T cells in rapidly progressive simian immunodeficiency virus infection. J. Exp. Med. 200, 1299-1314. (doi:10. 1084/jem.20041049)
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1299-1314
-
-
Picker, L.J.1
-
30
-
-
18844375363
-
HIV swiftly guts the immune system
-
(doi:10. 1038/nm0505-469)
-
Veazey RS, Lackner AA. 2005 HIV swiftly guts the immune system. Nat. Med. 11, 469-470. (doi:10. 1038/nm0505-469)
-
(2005)
Nat. Med.
, vol.11
, pp. 469-470
-
-
Veazey, R.S.1
Lackner, A.A.2
-
31
-
-
33845532053
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
-
(doi:10.1038/ nm1511)
-
Brenchley JM et al. 2006 Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat. Med. 12, 1365-1371. (doi:10.1038/ nm1511)
-
(2006)
Nat. Med.
, vol.12
, pp. 1365-1371
-
-
Brenchley, J.M.1
-
33
-
-
84867544493
-
SIV infection induces accumulation of plasmacytoid dendritic cells in the gut mucosa
-
(doi:10.1093/infdis/jis408)
-
Reeves RK, Evans TI, Gillis J, Wong FE, Kang G, Li Q, Johnson RP. 2012 SIV infection induces accumulation of plasmacytoid dendritic cells in the gut mucosa. J. Infect. Dis. 206, 1462-1468. (doi:10.1093/infdis/jis408)
-
(2012)
J. Infect. Dis.
, vol.206
, pp. 1462-1468
-
-
Reeves, R.K.1
Evans, T.I.2
Gillis, J.3
Wong, F.E.4
Kang, G.5
Li, Q.6
Johnson, R.P.7
-
34
-
-
79251555316
-
Blocking of alpha4beta7 guthoming integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques
-
(doi:10.4049/jimmunol.1003052)
-
Ansari AA et al. 2011 Blocking of alpha4beta7 guthoming integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. J. Immunol. 186, 1044-1059. (doi:10.4049/jimmunol.1003052)
-
(2011)
J. Immunol.
, vol.186
, pp. 1044-1059
-
-
Ansari, A.A.1
-
35
-
-
79953815415
-
Influence of the MHC genotype on the progression of experimental SIV infection in the Mauritian cynomolgus macaque
-
(doi:10.1007/s00251-010-0504-6)
-
Aarnink A, Dereuddre-Bosquet N, Vaslin B, Le Grand R, Winterton P, Apoil PA, Blancher A. 2011 Influence of the MHC genotype on the progression of experimental SIV infection in the Mauritian cynomolgus macaque. Immunogenetics 63, 267-274. (doi:10.1007/s00251-010-0504-6)
-
(2011)
Immunogenetics
, vol.63
, pp. 267-274
-
-
Aarnink, A.1
Dereuddre-Bosquet, N.2
Vaslin, B.3
Le Grand, R.4
Winterton, P.5
Apoil, P.A.6
Blancher, A.7
-
36
-
-
84883219358
-
Major histocompatibility complex class I haplotype diversity in Chinese rhesus macaques
-
(doi:10.1534/g3.113.006254)
-
Karl JA, Bohn PS, Wiseman RW, Nimityongskul FA, Lank SM, Starrett GJ, O'Connor DH. 2013 Major histocompatibility complex class I haplotype diversity in Chinese rhesus macaques. G3 (Bethesda) 3, 1195-1201. (doi:10.1534/g3.113.006254)
-
(2013)
G3 Bethesda
, vol.3
, pp. 1195-1201
-
-
Karl, J.A.1
Bohn, P.S.2
Wiseman, R.W.3
Nimityongskul, F.A.4
Lank, S.M.5
Starrett, G.J.6
O'Connor, D.H.7
-
37
-
-
84883435285
-
TRIM5 alpha drives SIVsmm evolution in rhesus macaques
-
(doi:10.1371/journal.ppat.1003577)
-
Wu F et al. 2013 TRIM5 alpha drives SIVsmm evolution in rhesus macaques. PLoS Pathog. 9, e1003577. (doi:10.1371/journal.ppat.1003577)
-
(2013)
PLoS Pathog.
, vol.9
-
-
Wu, F.1
-
38
-
-
16244408954
-
+-T-cell loss in simian immunodeficiency virus SIVagm-infected pigtailed macaques: Variable pathogenicity of natural SIVagm isolates
-
(doi:10.1128/JVI.79.8.5153-5162.2005)
-
+-T-cell loss in simian immunodeficiency virus SIVagm-infected pigtailed macaques: variable pathogenicity of natural SIVagm isolates. J. Virol. 79, 5153-5162. (doi:10.1128/JVI.79.8.5153-5162.2005)
-
(2005)
J. Virol.
, vol.79
, pp. 5153-5162
-
-
Goldstein, S.1
Ourmanov, I.2
Brown, C.R.3
Plishka, R.4
Buckler-White, A.5
Byrum, R.6
Hirsch, V.M.7
-
39
-
-
80052314332
-
+ cell depletion
-
(doi:10. 1371/journal.ppat.1002170)
-
+ cell depletion. PLoS Pathog. 7, e1002170. (doi:10. 1371/journal.ppat.1002170)
-
(2011)
PLoS Pathog.
, vol.7
-
-
Pandrea, I.1
-
40
-
-
0033861039
-
High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys
-
(doi:10.1128/JVI.74.16.7538-7547.2000)
-
Diop OM et al. 2000 High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys. J. Virol. 74, 7538-7547. (doi:10.1128/JVI.74.16.7538-7547.2000)
-
(2000)
J. Virol.
, vol.74
, pp. 7538-7547
-
-
Diop, O.M.1
-
41
-
-
77956906960
-
Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion
-
(doi:10.1186/1742-4690-7-78)
-
Bourry O, Mannioui A, Sellier P, Roucairol C, Durand-Gasselin L, Dereuddre-Bosquet N, Benech H, Roques P, Le Grand R. 2010 Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion. Retrovirology 7, 78. (doi:10.1186/1742-4690-7-78)
-
(2010)
Retrovirology
, vol.7
, pp. 78
-
-
Bourry, O.1
Mannioui, A.2
Sellier, P.3
Roucairol, C.4
Durand-Gasselin, L.5
Dereuddre-Bosquet, N.6
Benech, H.7
Roques, P.8
Le Grand, R.9
-
42
-
-
50949097030
-
Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel
-
(doi:10.1371/ journal.pmed.0050157)
-
Cranage M et al. 2008 Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel. PLoS Med. 5, e157. (doi:10.1371/ journal.pmed.0050157)
-
(2008)
PLoS Med.
, vol.5
-
-
Cranage, M.1
-
43
-
-
84866150865
-
Nonhuman primate models for HIV cure research
-
(doi:10.1371/journal.ppat.1002892)
-
Apetrei C, Pandrea I, Mellors JW. 2012 Nonhuman primate models for HIV cure research. PLoS Pathog. 8, e1002892. (doi:10.1371/journal.ppat.1002892)
-
(2012)
PLoS Pathog.
, vol.8
-
-
Apetrei, C.1
Pandrea, I.2
Mellors, J.W.3
-
44
-
-
84864051807
-
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model
-
(doi:10.1371/journal.ppat.1002774)
-
Shytaj IL. 2012 A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. PLoS Pathog. 8, e1002774. (doi:10.1371/journal.ppat.1002774)
-
(2012)
PLoS Pathog.
, vol.8
-
-
Shytaj, I.L.1
-
45
-
-
68349157582
-
Toward an AIDS vaccine: Lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts
-
(doi:10.1038/nm.2013)
-
Sodora DL et al. 2009 Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nat. Med. 15, 861-865. (doi:10.1038/nm.2013)
-
(2009)
Nat. Med.
, vol.15
, pp. 861-865
-
-
Sodora, D.L.1
-
46
-
-
59649097925
-
African non human primates infected by SIV-why don't they get sick? Lessons from studies on the early phase of nonpathogenic SIV infection
-
(doi:10.2174/157016209787048546)
-
Liovat AS, Jacquelin B, Ploquin MJ, Barre-Sinoussi F, Muller-Trutwin MC. 2009 African non human primates infected by SIV-why don't they get sick? Lessons from studies on the early phase of nonpathogenic SIV infection. Curr. HIV Res. 7, 39-50. (doi:10.2174/157016209787048546)
-
(2009)
Curr. HIV Res.
, vol.7
, pp. 39-50
-
-
Liovat, A.S.1
Jacquelin, B.2
Ploquin, M.J.3
Barre-Sinoussi, F.4
Muller-Trutwin, M.C.5
-
47
-
-
20144387661
-
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
-
(doi:10.1172/ JCI23006)
-
Kornfeld C et al. 2005 Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS. J. Clin. Invest. 115, 1082-1091. (doi:10.1172/ JCI23006)
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1082-1091
-
-
Kornfeld, C.1
-
48
-
-
84887160135
-
Immune activation, HIV persistence, and the cure
-
Douek DC. 2013 Immune activation, HIV persistence, and the cure. Top. Antiviral Med. 21, 128-132.
-
(2013)
Top. Antiviral Med.
, vol.21
, pp. 128-132
-
-
Douek, D.C.1
-
49
-
-
43149099234
-
Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals
-
(doi:10.1097/QAD. 0b013e3282f56b23)
-
Boulet S, Sharafi S, Simic N, Bruneau J, Routy JP, Tsoukas CM, Bernard NF. 2008 Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals. AIDS 22, 595-599. (doi:10.1097/QAD. 0b013e3282f56b23)
-
(2008)
AIDS
, vol.22
, pp. 595-599
-
-
Boulet, S.1
Sharafi, S.2
Simic, N.3
Bruneau, J.4
Routy, J.P.5
Tsoukas, C.M.6
Bernard, N.F.7
-
50
-
-
33750802673
-
Cutting edge: Resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands
-
Jennes W, Verheyden S, Demanet C, Adje-Toure CA, Vuylsteke B, Nkengasong JN, Kestens L. 2006 Cutting edge: resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands. J. Immunol. 177, 6588-6592.
-
(2006)
J. Immunol.
, vol.177
, pp. 6588-6592
-
-
Jennes, W.1
Verheyden, S.2
Demanet, C.3
Adje-Toure, C.A.4
Vuylsteke, B.5
Nkengasong, J.N.6
Kestens, L.7
-
52
-
-
34248368553
-
Distinctive NK-cell receptor repertoires sustain high-level constitutive NK-cell activation in HIV-exposed uninfected individuals
-
(doi:10.1182/blood-2006-08-040238)
-
Ravet S et al. 2007 Distinctive NK-cell receptor repertoires sustain high-level constitutive NK-cell activation in HIV-exposed uninfected individuals. Blood 109, 4296-4305. (doi:10.1182/blood-2006-08-040238)
-
(2007)
Blood
, vol.109
, pp. 4296-4305
-
-
Ravet, S.1
-
53
-
-
0344585525
-
Cutting edge: Increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug users
-
Scott-Algara D, Truong LX, Versmisse P, David A, Luong TT, Nguyen NV, Theodorou I, Barre-Sinoussi F, Pancino G. 2003 Cutting edge: increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug users. J. Immunol. 171, 5663-5667.
-
(2003)
J. Immunol.
, vol.171
, pp. 5663-5667
-
-
Scott-Algara, D.1
Truong, L.X.2
Versmisse, P.3
David, A.4
Luong, T.T.5
Nguyen, N.V.6
Theodorou, I.7
Barre-Sinoussi, F.8
Pancino, G.9
-
54
-
-
34248140162
-
Evolution of innate and adaptive effector cell functions during acute HIV-1 infection
-
(doi:10.1086/513878)
-
Alter G, Teigen N, Ahern R, Streeck H, Meier A, Rosenberg ES, Altfeld M. 2007 Evolution of innate and adaptive effector cell functions during acute HIV-1 infection. J. Infect. Dis. 195, 1452-1460. (doi:10.1086/513878)
-
(2007)
J. Infect. Dis.
, vol.195
, pp. 1452-1460
-
-
Alter, G.1
Teigen, N.2
Ahern, R.3
Streeck, H.4
Meier, A.5
Rosenberg, E.S.6
Altfeld, M.7
-
55
-
-
27744464537
-
Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection
-
(doi:10.1182/blood-2005-03-1100)
-
Alter G et al. 2005 Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection. Blood 106, 3366-3369. (doi:10.1182/blood-2005-03-1100)
-
(2005)
Blood
, vol.106
, pp. 3366-3369
-
-
Alter, G.1
-
56
-
-
84865560190
-
Evasion from NK cell-mediated immune responses by HIV-1
-
(doi:10.1016/j.micinf.2012.05.001)
-
Jost S, Altfeld M. 2012 Evasion from NK cell-mediated immune responses by HIV-1. Microbes Infect. 14, 904-915. (doi:10.1016/j.micinf.2012.05.001)
-
(2012)
Microbes Infect.
, vol.14
, pp. 904-915
-
-
Jost, S.1
Altfeld, M.2
-
57
-
-
0036699528
-
Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS
-
(doi:10.1038/ng934)
-
Martin MP et al. 2002 Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat. Genet. 31, 429-434. (doi:10.1038/ng934)
-
(2002)
Nat. Genet.
, vol.31
, pp. 429-434
-
-
Martin, M.P.1
-
58
-
-
34249802335
-
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1
-
(doi:10.1038/ng2035)
-
Martin MP et al. 2007 Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat. Genet. 39, 733-740. (doi:10.1038/ng2035)
-
(2007)
Nat. Genet.
, vol.39
, pp. 733-740
-
-
Martin, M.P.1
-
59
-
-
67449101826
-
+ NK cells during acute human immunodeficiency virus type 1 infection
-
(doi:10.1128/JVI.00256-09)
-
+ NK cells during acute human immunodeficiency virus type 1 infection. J. Virol. 83, 6798-6805. (doi:10.1128/JVI.00256-09)
-
(2009)
J. Virol.
, vol.83
, pp. 6798-6805
-
-
Alter, G.1
Rihn, S.2
Walter, K.3
Nolting, A.4
Martin, M.5
Rosenberg, E.S.6
Miller, J.S.7
Carrington, M.8
Altfeld, M.9
-
60
-
-
42949129193
-
HLA alleles determine differences in human natural killer cell responsiveness and potency
-
(doi:10.1073/pnas.0712229105)
-
Kim S et al. 2008 HLA alleles determine differences in human natural killer cell responsiveness and potency. Proc. Natl Acad. Sci. USA 105, 3053-3058. (doi:10.1073/pnas.0712229105)
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 3053-3058
-
-
Kim, S.1
-
61
-
-
77953414590
-
Peptide antagonism as a mechanism for NK cell activation
-
(doi:10.1073/pnas. 0913745107)
-
Fadda L et al. 2010 Peptide antagonism as a mechanism for NK cell activation. Proc. Natl Acad. Sci. USA 107, 10 160-10 165. (doi:10.1073/pnas. 0913745107)
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10160-10165
-
-
Fadda, L.1
-
62
-
-
33845953843
-
Cutting edge: Allelespecific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B
-
Thananchai H et al. 2007 Cutting edge: allelespecific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B. J. Immunol. 178, 33-37.
-
(2007)
J. Immunol.
, vol.178
, pp. 33-37
-
-
Thananchai, H.1
-
63
-
-
81555213587
-
Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B
-
(doi:10. 1038/nature10517)
-
Vivian JP et al. 2011 Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B. Nature 479, 401-405. (doi:10. 1038/nature10517)
-
(2011)
Nature
, vol.479
, pp. 401-405
-
-
Vivian, J.P.1
-
64
-
-
79961138654
-
HIV-1 adaptation to NK-cellmediated immune pressure
-
(doi:10.1038/nature10237)
-
Alter G et al. 2011 HIV-1 adaptation to NK-cellmediated immune pressure. Nature 476, 96-100. (doi:10.1038/nature10237)
-
(2011)
Nature
, vol.476
, pp. 96-100
-
-
Alter, G.1
-
65
-
-
0034646143
-
HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors
-
(doi:10. 1073/pnas.050567397)
-
Migueles SA et al. 2000 HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors. Proc. Natl Acad. Sci. USA 97, 2709-2714. (doi:10. 1073/pnas.050567397)
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 2709-2714
-
-
Migueles, S.A.1
-
66
-
-
78650084232
-
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
-
(doi:10.1126/science.1195271)
-
Pereyra F et al. 2010 The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science 330, 1551-1557. (doi:10.1126/science.1195271)
-
(2010)
Science
, vol.330
, pp. 1551-1557
-
-
Pereyra, F.1
-
67
-
-
34249852256
-
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
-
(doi:10.1073/pnas. 0611244104)
-
Saez-Cirion A et al. 2007 HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc. Natl Acad. Sci. USA 104, 6776-6781. (doi:10.1073/pnas. 0611244104)
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 6776-6781
-
-
Saez-Cirion, A.1
-
68
-
-
0035942184
-
Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity
-
(doi:10.1073/pnas. 071548198)
-
Flores-Villanueva PO et al. 2001 Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity. Proc. Natl Acad. Sci. USA 98, 5140-5145. (doi:10.1073/pnas. 071548198)
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 5140-5145
-
-
Flores-Villanueva, P.O.1
-
69
-
-
84880351147
-
Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation
-
(doi:10.1073/pnas.1302090110)
-
Marras F et al. 2013 Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation. Proc. Natl Acad. Sci. USA 110, 11 970-11 975. (doi:10.1073/pnas.1302090110)
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 11970-11975
-
-
Marras, F.1
-
70
-
-
84866735381
-
Impact of protective killer inhibitory receptor/ human leukocyte antigen genotypes on natural killer cell and T-cell function in HIV-1-infected controllers
-
(doi:10.1097/ QAD.0b013e32835861b0)
-
Tomescu C, Duh FM, Hoh R, Viviani A, Harvill K, Martin MP, Carrington M, Deeks SG, Montaner LJ. 2012 Impact of protective killer inhibitory receptor/ human leukocyte antigen genotypes on natural killer cell and T-cell function in HIV-1-infected controllers. AIDS 26, 1869-1878. (doi:10.1097/ QAD.0b013e32835861b0)
-
(2012)
AIDS
, vol.26
, pp. 1869-1878
-
-
Tomescu, C.1
Duh, F.M.2
Hoh, R.3
Viviani, A.4
Harvill, K.5
Martin, M.P.6
Carrington, M.7
Deeks, S.G.8
Montaner, L.J.9
-
71
-
-
77950210095
-
Specific phenotypic and functional features of natural killer cells from HIV-infected long-term nonprogressors and HIV controllers
-
(doi:10.1097/ QAI.0b013e3181d0c5b4)
-
Vieillard V, Fausther-Bovendo H, Samri A, Debre P. 2010 Specific phenotypic and functional features of natural killer cells from HIV-infected long-term nonprogressors and HIV controllers. J. Acquir. Immune Defic. Syndr. 53, 564-573. (doi:10.1097/ QAI.0b013e3181d0c5b4)
-
(2010)
J. Acquir. Immune Defic. Syndr.
, vol.53
, pp. 564-573
-
-
Vieillard, V.1
Fausther-Bovendo, H.2
Samri, A.3
Debre, P.4
-
72
-
-
65349168831
-
Role of natural killer cells in a cohort of elite suppressors: Low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro
-
(doi:10.1128/JVI. 02551-08)
-
O'Connell KA, Han Y, Williams TM, Siliciano RF, Blankson JN. 2009 Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro. J. Virol. 83, 5028-5034. (doi:10.1128/JVI. 02551-08)
-
(2009)
J. Virol.
, vol.83
, pp. 5028-5034
-
-
O'Connell, K.A.1
Han, Y.2
Williams, T.M.3
Siliciano, R.F.4
Blankson, J.N.5
-
73
-
-
29144467887
-
Role for plasmacytoid dendritic cells in anti-HIV innate immunity
-
(doi:10.1111/j.1440-1711.2005.01394.x)
-
Muller-Trutwin M, Hosmalin A. 2005 Role for plasmacytoid dendritic cells in anti-HIV innate immunity. Immunol. Cell Biol. 83, 578-583. (doi:10.1111/j.1440-1711.2005.01394.x)
-
(2005)
Immunol. Cell Biol.
, vol.83
, pp. 578-583
-
-
Muller-Trutwin, M.1
Hosmalin, A.2
-
74
-
-
84857374815
-
Role of retroviral restriction factors in the interferon-alpha-mediated suppression of HIV-1 in vivo
-
(doi:10.1073/pnas. 1111573109)
-
Pillai SK et al. 2012 Role of retroviral restriction factors in the interferon-alpha-mediated suppression of HIV-1 in vivo. Proc. Natl Acad. Sci. USA 109, 3035-3040. (doi:10.1073/pnas. 1111573109)
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 3035-3040
-
-
Pillai, S.K.1
-
75
-
-
0024364803
-
Interferon-alpha but not AZT suppresses HIV expression in chronically infected cell lines
-
(doi:10.1126/science.2470148)
-
Poli G, Orenstein JM, Kinter A, Folks TM, Fauci AS. 1989 Interferon-alpha but not AZT suppresses HIV expression in chronically infected cell lines. Science 244, 575-577. (doi:10.1126/science.2470148)
-
(1989)
Science
, vol.244
, pp. 575-577
-
-
Poli, G.1
Orenstein, J.M.2
Kinter, A.3
Folks, T.M.4
Fauci, A.S.5
-
76
-
-
3343012408
-
Peginterferon Alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patients
-
(doi:10.1056/NEJMoa040842)
-
Torriani FJ et al. 2004 Peginterferon Alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patients. N. Engl. J. Med. 351, 438-450. (doi:10.1056/NEJMoa040842)
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 438-450
-
-
Torriani, F.J.1
-
77
-
-
0022573263
-
Human alpha-and betainterferon but not gamma suppress the in vitro replication of LAV, HTLV-III, and ARV-2
-
(doi:10.1089/jir.1986.6.143)
-
Yamamoto JK, Barre-Sinoussi F, Bolton V, Pedersen NC, Gardner MB. 1986 Human alpha-and betainterferon but not gamma suppress the in vitro replication of LAV, HTLV-III, and ARV-2. J. Interferon Res. 6, 143-152. (doi:10.1089/jir.1986.6.143)
-
(1986)
J. Interferon Res.
, vol.6
, pp. 143-152
-
-
Yamamoto, J.K.1
Barre-Sinoussi, F.2
Bolton, V.3
Pedersen, N.C.4
Gardner, M.B.5
-
78
-
-
84855272511
-
+ cells from individuals with Aicardi-Goutieres syndrome are highly susceptible to HIV-1 infection
-
(doi:10.1371/journal.ppat. 1002425)
-
+ cells from individuals with Aicardi-Goutieres syndrome are highly susceptible to HIV-1 infection. PLoS Pathog. 7, e1002425. (doi:10.1371/journal.ppat. 1002425)
-
(2011)
PLoS Pathog.
, vol.7
-
-
Berger, A.1
-
79
-
-
62849103646
-
Human TRIM gene expression in response to interferons
-
(doi:10.1371/journal.pone.0004894)
-
Carthagena L et al. 2009 Human TRIM gene expression in response to interferons. PLoS ONE 4, e4894. (doi:10.1371/journal.pone.0004894)
-
(2009)
PLoS ONE
, vol.4
-
-
Carthagena, L.1
-
80
-
-
84886953102
-
Human MX2 is an interferoninduced post-entry inhibitor of HIV-1 infection
-
(doi:10.1038/nature12542)
-
Goujon C et al. 2013 Human MX2 is an interferoninduced post-entry inhibitor of HIV-1 infection. Nature 502, 559-562. (doi:10.1038/nature12542)
-
(2013)
Nature
, vol.502
, pp. 559-562
-
-
Goujon, C.1
-
81
-
-
84886949134
-
MX2 is an interferon-induced inhibitor of HIV-1 infection
-
(doi:10.1038/nature12653)
-
Kane M et al. 2013 MX2 is an interferon-induced inhibitor of HIV-1 infection. Nature 502, 563-566. (doi:10.1038/nature12653)
-
(2013)
Nature
, vol.502
, pp. 563-566
-
-
Kane, M.1
-
82
-
-
44649102135
-
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
-
(doi:10.1073/ pnas.0802203105)
-
Keele BF et al. 2008 Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl Acad. Sci. USA 105, 7552-7557. (doi:10.1073/ pnas.0802203105)
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 7552-7557
-
-
Keele, B.F.1
-
83
-
-
84888776867
-
Relative resistance of HIV-1 founder viruses to control by interferonalpha
-
(doi:10.1186/1742-4690-10-146)
-
Fenton-May AE et al. 2013 Relative resistance of HIV-1 founder viruses to control by interferonalpha. Retrovirology 10, 146. (doi:10.1186/1742-4690-10-146)
-
(2013)
Retrovirology
, vol.10
, pp. 146
-
-
Fenton-May, A.E.1
-
84
-
-
84876867850
-
Phenotypic properties of transmitted founder HIV-1
-
(doi:10.1073/pnas.1304288110)
-
Parrish NF et al. 2013 Phenotypic properties of transmitted founder HIV-1. Proc. Natl Acad. Sci. USA 110, 6626-6633. (doi:10.1073/pnas.1304288110)
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 6626-6633
-
-
Parrish, N.F.1
-
85
-
-
77956113383
-
Type I interferon modulates the battle of host immune system against viruses
-
(doi:10.1016/ S0065-2164(10)73004-5)
-
Seo YJ, Hahm B. 2010 Type I interferon modulates the battle of host immune system against viruses. Adv. Appl. Microbiol. 73, 83-101. (doi:10.1016/ S0065-2164(10)73004-5)
-
(2010)
Adv. Appl. Microbiol.
, vol.73
, pp. 83-101
-
-
Seo, Y.J.1
Hahm, B.2
-
86
-
-
77949409948
-
Targeting early infection to prevent HIV-1 mucosal transmission
-
(doi:10.1038/nature08757)
-
Haase AT. 2010 Targeting early infection to prevent HIV-1 mucosal transmission. Nature 464, 217-223. (doi:10.1038/nature08757)
-
(2010)
Nature
, vol.464
, pp. 217-223
-
-
Haase, A.T.1
-
87
-
-
77952977625
-
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease
-
(doi:10.1126/scitranslmed.3000632)
-
Favre D et al. 2010 Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci. Transl. Med. 2, 32ra36. (doi:10.1126/scitranslmed.3000632)
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Favre, D.1
-
88
-
-
33646468496
-
Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients
-
(doi:10.1073/pnas.0600363103)
-
Herbeuval JP et al. 2006 Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients. Proc. Natl Acad. Sci. USA 103, 7000-7005. (doi:10.1073/pnas.0600363103)
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 7000-7005
-
-
Herbeuval, J.P.1
-
89
-
-
58149380860
-
Primary infection with simian immunodeficiency virus: Plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression
-
(doi:10.1182/blood-2008-06-162651)
-
Malleret B et al. 2008 Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression. Blood 112, 4598-4608. (doi:10.1182/blood-2008-06-162651)
-
(2008)
Blood
, vol.112
, pp. 4598-4608
-
-
Malleret, B.1
-
90
-
-
84864936397
-
Plasmacytoid dendritic cells (pDCs) from HIV controllers produce interferonalpha and differentiate into functional killer pDCs under HIV activation
-
(doi:10.1093/infdis/jis384)
-
Barblu L, Machmach K, Gras C, Delfraissy JF, Boufassa F, Leal M, Ruiz-Mateos E, Lambotte O, Herbeuval JP. 2012 Plasmacytoid dendritic cells (pDCs) from HIV controllers produce interferonalpha and differentiate into functional killer pDCs under HIV activation. J. Infect. Dis. 206, 790-801. (doi:10.1093/infdis/jis384)
-
(2012)
J. Infect. Dis.
, vol.206
, pp. 790-801
-
-
Barblu, L.1
McHmach, K.2
Gras, C.3
Delfraissy, J.F.4
Boufassa, F.5
Leal, M.6
Ruiz-Mateos, E.7
Lambotte, O.8
Herbeuval, J.P.9
-
91
-
-
84861384888
-
Plasmacytoid dendritic cells reduce HIV production in elite controllers
-
(doi:10.1128/JVI.07114-11)
-
Machmach K et al. 2012 Plasmacytoid dendritic cells reduce HIV production in elite controllers. J. Virol. 86, 4245-4252. (doi:10.1128/JVI.07114-11)
-
(2012)
J. Virol.
, vol.86
, pp. 4245-4252
-
-
McHmach, K.1
-
92
-
-
70450193060
-
The CDK inhibitor p21Cip1/WAF1 is induced by FcgR activation and restricts the replication of human immunodeficiency virus type 1 and related primate lentiviruses in human macrophages
-
(doi:10.1128/JVI.01395-09)
-
Bergamaschi A, David A, Le Rouzic E, Nisole S, Barre-Sinoussi F, Pancino G. 2009 The CDK inhibitor p21Cip1/WAF1 is induced by FcgR activation and restricts the replication of human immunodeficiency virus type 1 and related primate lentiviruses in human macrophages. J. Virol. 83, 12 253-12 265. (doi:10.1128/JVI.01395-09)
-
(2009)
J. Virol.
, vol.83
, pp. 12253-12265
-
-
Bergamaschi, A.1
David, A.2
Le Rouzic, E.3
Nisole, S.4
Barre-Sinoussi, F.5
Pancino, G.6
-
93
-
-
84887279415
-
APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host
-
(doi:10.1371/journal.ppat.1003641)
-
Krupp A, McCarthy KR, Ooms M, Letko M, Morgan JS, Simon V, Johnson WE. 2013 APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host. PLoS Pathog. 9, e1003641. (doi:10.1371/journal.ppat.1003641)
-
(2013)
PLoS Pathog.
, vol.9
-
-
Krupp, A.1
McCarthy, K.R.2
Ooms, M.3
Letko, M.4
Morgan, J.S.5
Simon, V.6
Johnson, W.E.7
-
94
-
-
84878956988
-
HIV restriction factors and mechanisms of evasion
-
(doi:10.1101/ cshperspect.a006940)
-
Malim MH, Bieniasz PD. 2012 HIV restriction factors and mechanisms of evasion. Cold Spring Harb. Perspect. Med. 2, a006940. (doi:10.1101/ cshperspect.a006940)
-
(2012)
Cold Spring Harb. Perspect. Med.
, vol.2
-
-
Malim, M.H.1
Bieniasz, P.D.2
-
95
-
-
40349103653
-
The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection
-
(doi:10.1371/journal. ppat.0040018)
-
van Manen D, Rits MA, Beugeling C, van Dort K, Schuitemaker H, Kootstra NA. 2008 The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection. PLoS Pathog. 4, e18. (doi:10.1371/journal. ppat.0040018)
-
(2008)
PLoS Pathog.
, vol.4
-
-
van Manen, D.1
Rits, M.A.2
Beugeling, C.3
van Dort, K.4
Schuitemaker, H.5
Kootstra, N.A.6
-
97
-
-
19944426225
-
Exhaustive genotyping of the CEM15 (APOBEC3G) gene and absence of association with AIDS progression in a French cohort
-
(doi:10.1086/426826)
-
Do H et al. 2005 Exhaustive genotyping of the CEM15 (APOBEC3G) gene and absence of association with AIDS progression in a French cohort. J. Infect. Dis. 191, 159-163. (doi:10.1086/426826)
-
(2005)
J. Infect. Dis.
, vol.191
, pp. 159-163
-
-
Do, H.1
-
98
-
-
67650675663
-
Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection
-
(doi:10. 1086/598861)
-
Sewram S, Singh R, Kormuth E, Werner L, Mlisana K, Karim SS, Ndung'u T. 2009 Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection. J. Infect. Dis. 199, 1657-1663. (doi:10. 1086/598861)
-
(2009)
J. Infect. Dis.
, vol.199
, pp. 1657-1663
-
-
Sewram, S.1
Singh, R.2
Kormuth, E.3
Werner, L.4
Mlisana, K.5
Karim, S.S.6
Ndung'U, T.7
-
99
-
-
77649269022
-
+ T-cells from HIV-1-infected individuals
-
(doi:10.1371/journal.ppat.1000781)
-
+ T-cells from HIV-1-infected individuals. PLoS Pathog. 6, e1000781. (doi:10.1371/journal.ppat.1000781)
-
(2010)
PLoS Pathog.
, vol.6
-
-
Rotger, M.1
-
100
-
-
12644274812
-
Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure
-
(doi:10.1038/ nm0496-412)
-
Paxton WA et al. 1996 Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure. Nat. Med. 2, 412-417. (doi:10.1038/ nm0496-412)
-
(1996)
Nat. Med.
, vol.2
, pp. 412-417
-
-
Paxton, W.A.1
-
101
-
-
33751185929
-
Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks
-
(doi:10.1186/ 1742-4690-3-81)
-
Saez-Cirion A, Versmisse P, Truong LX, Chakrabarti LA, Carpentier W, Barre-Sinoussi F, Scott-Algara D, Pancino G. 2006 Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks. Retrovirology 3, 81. (doi:10.1186/ 1742-4690-3-81)
-
(2006)
Retrovirology
, vol.3
, pp. 81
-
-
Saez-Cirion, A.1
Versmisse, P.2
Truong, L.X.3
Chakrabarti, L.A.4
Carpentier, W.5
Barre-Sinoussi, F.6
Scott-Algara, D.7
Pancino, G.8
-
102
-
-
79953305839
-
+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21
-
(doi:10.1172/JCI44539)
-
+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21. J. Clin. Invest. 121, 1549-1560. (doi:10.1172/JCI44539)
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1549-1560
-
-
Chen, H.1
-
103
-
-
79961008229
-
+ T cells from HIV controllers
-
(doi:10.1182/ blood-2010-12-327106)
-
+ T cells from HIV controllers. Blood 118, 955-964. (doi:10.1182/ blood-2010-12-327106)
-
(2011)
Blood
, vol.118
, pp. 955-964
-
-
Saez-Cirion, A.1
-
104
-
-
0028337166
-
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
-
Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, Farthing C, Ho DD. 1994 Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68, 4650-4655.
-
(1994)
J. Virol.
, vol.68
, pp. 4650-4655
-
-
Koup, R.A.1
Safrit, J.T.2
Cao, Y.3
Andrews, C.A.4
McLeod, G.5
Borkowsky, W.6
Farthing, C.7
Ho, D.D.8
-
105
-
-
16944365445
-
Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
-
(doi:10. 1038/nm0297-205)
-
Borrow P et al. 1997 Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat. Med. 3, 205-211. (doi:10. 1038/nm0297-205)
-
(1997)
Nat. Med.
, vol.3
, pp. 205-211
-
-
Borrow, P.1
-
106
-
-
33846101731
-
+ T-cell responses to different HIV proteins have discordant associations with viral load
-
(doi:10.1038/ nm1520)
-
+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat. Med. 13, 46-53. (doi:10.1038/ nm1520)
-
(2007)
Nat. Med.
, vol.13
, pp. 46-53
-
-
Kiepiela, P.1
-
107
-
-
0028978720
-
Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex or AIDS
-
(doi:10.1089/ aid.1995.11.903)
-
Riviere Y et al. 1995 Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex or AIDS. AIDS Res. Hum. Retroviruses 11, 903-907. (doi:10.1089/ aid.1995.11.903)
-
(1995)
AIDS Res. Hum. Retroviruses
, vol.11
, pp. 903-907
-
-
Riviere, Y.1
-
108
-
-
33645240933
-
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1
-
(doi:10.1128/JVI.80.7.3617-3623.2006)
-
Martinez-Picado J et al. 2006 Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J. Virol. 80, 3617-3623. (doi:10.1128/JVI.80.7.3617-3623.2006)
-
(2006)
J. Virol.
, vol.80
, pp. 3617-3623
-
-
Martinez-Picado, J.1
-
109
-
-
0031985775
-
Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques
-
Matano T, Shibata R, Siemon C, Connors M, Lane HC, Martin MA. 1998 Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques. J. Virol. 72, 164-169.
-
(1998)
J. Virol
, vol.72
, pp. 164-169
-
-
Matano, T.1
Shibata, R.2
Siemon, C.3
Connors, M.4
Lane, H.C.5
Martin, M.A.6
-
110
-
-
67650457719
-
+ lymphocyte depletion but does not account for accelerated SIV pathogenesis
-
(doi:10.1084/jem.20090356)
-
+ lymphocyte depletion but does not account for accelerated SIV pathogenesis. J. Exp. Med. 206, 1575-1588. (doi:10.1084/jem.20090356)
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1575-1588
-
-
Okoye, A.1
-
111
-
-
0033559648
-
+ T cell depletion in simian immunodeficiency virus-infected macaques
-
(doi:10.1084/jem.189.6.991)
-
+ T cell depletion in simian immunodeficiency virus-infected macaques. J. Exp. Med. 189, 991-998. (doi:10.1084/jem.189.6.991)
-
(1999)
J. Exp. Med.
, vol.189
, pp. 991-998
-
-
Jin, X.1
-
112
-
-
0032986421
-
+ lymphocytes using a mouse-human chimeric monoclonal antibody
-
(doi:10. 1016/S0002-9440(10)65450-8)
-
+ lymphocytes using a mouse-human chimeric monoclonal antibody. Am. J. Pathol. 154, 1923-1932. (doi:10. 1016/S0002-9440(10)65450-8)
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1923-1932
-
-
Schmitz, J.E.1
-
114
-
-
0022967777
-
+ lymphocytes can control HIV infection in vitro by suppressing virus replication
-
(doi:10.1126/science.2431484)
-
+ lymphocytes can control HIV infection in vitro by suppressing virus replication. Science 234, 1563-1566. (doi:10.1126/science.2431484)
-
(1986)
Science
, vol.234
, pp. 1563-1566
-
-
Walker, C.M.1
Moody, D.J.2
Stites, D.P.3
Levy, J.A.4
-
115
-
-
0028608085
-
+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity
-
(doi:10.1002/eji.1830241223)
-
+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. Eur. J. Immunol. 24, 3068-3072. (doi:10.1002/eji.1830241223)
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 3068-3072
-
-
Kagi, D.1
Ledermann, B.2
Burki, K.3
Hengartner, H.4
Zinkernagel, R.M.5
-
116
-
-
0027937745
-
Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
-
(doi:10.1038/370650a0)
-
Lowin B, Hahne M, Mattmann C, Tschopp J. 1994 Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 370, 650-652. (doi:10.1038/370650a0)
-
(1994)
Nature
, vol.370
, pp. 650-652
-
-
Lowin, B.1
Hahne, M.2
Mattmann, C.3
Tschopp, J.4
-
117
-
-
84857059757
-
Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells
-
(doi:10.1097/COH.0b013e328 34ddcf2)
-
Youngblood B, Wherry EJ, Ahmed R. 2012 Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells. Curr. Opin. HIV AIDS 7, 50-57. (doi:10.1097/COH.0b013e328 34ddcf2)
-
(2012)
Curr. Opin. HIV AIDS
, vol.7
, pp. 50-57
-
-
Youngblood, B.1
Wherry, E.J.2
Ahmed, R.3
-
118
-
-
0035282444
-
Skewed maturation of memory HIV-specific CD8 T lymphocytes
-
(doi:10.1038/35065118)
-
Champagne P et al. 2001 Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 410, 106-111. (doi:10.1038/35065118)
-
(2001)
Nature
, vol.410
, pp. 106-111
-
-
Champagne, P.1
-
119
-
-
19344370239
-
+ T-cell differentiation towards senescence in HIV-1 infection
-
(doi:10.1371/journal. pbio.0020020)
-
+ T-cell differentiation towards senescence in HIV-1 infection. PLoS Biol. 2, E20. (doi:10.1371/journal. pbio.0020020)
-
(2004)
PLoS Biol.
, vol.2
-
-
Papagno, L.1
-
120
-
-
0034661671
-
+ T cells in HIVinfected progressors and long-term nonprogressors
-
+ T cells in HIVinfected progressors and long-term nonprogressors. J. Immunol. 165, 1082-1092.
-
(2000)
J. Immunol.
, vol.165
, pp. 1082-1092
-
-
Gea-Banacloche, J.C.1
-
121
-
-
33646686040
-
+ T cells
-
(doi:10.1182/blood-2005-12-4818)
-
+ T cells. Blood 107, 4781-4789. (doi:10.1182/blood-2005-12-4818)
-
(2006)
Blood
, vol.107
, pp. 4781-4789
-
-
Betts, M.R.1
-
122
-
-
0036852179
-
+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
-
(doi:10.1038/ni845)
-
+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors. Nat. Immunol. 3, 1061-1068. (doi:10.1038/ni845)
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1061-1068
-
-
Migueles, S.A.1
-
123
-
-
55949118498
-
Flow cytometric detection of perforin upregulation in human CD8 T cells
-
(doi:10.1002/cyto.a.20596)
-
Hersperger AR, Makedonas G, Betts MR. 2008 Flow cytometric detection of perforin upregulation in human CD8 T cells. Cytometry A 73, 1050-1057. (doi:10.1002/cyto.a.20596)
-
(2008)
Cytometry A
, vol.73
, pp. 1050-1057
-
-
Hersperger, A.R.1
Makedonas, G.2
Betts, M.R.3
-
124
-
-
57449109484
-
+ T cells is required for HIV-infected cell elimination associated with immune control
-
(doi:10.1016/j.immuni. 2008.10.010)
-
+ T cells is required for HIV-infected cell elimination associated with immune control. Immunity 29, 1009-1021. (doi:10.1016/j.immuni. 2008.10.010)
-
(2008)
Immunity
, vol.29
, pp. 1009-1021
-
-
Migueles, S.A.1
-
125
-
-
67649213034
-
Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: Association with Gag-specific CD8 T cell responses
-
(doi:10.4049/ jimmunol.0803928)
-
Saez-Cirion A et al. 2009 Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses. J. Immunol. 182, 7828-7837. (doi:10.4049/ jimmunol.0803928)
-
(2009)
J. Immunol.
, vol.182
, pp. 7828-7837
-
-
Saez-Cirion, A.1
-
126
-
-
33847388794
-
+ T lymphocytes recognize infected cells before AIDSvirus integration and viral protein expression
-
+ T lymphocytes recognize infected cells before AIDSvirus integration and viral protein expression. J. Immunol. 178, 2746-2754.
-
(2007)
J. Immunol.
, vol.178
, pp. 2746-2754
-
-
Sacha, J.B.1
-
127
-
-
84875529857
-
CD8 T-cells from most HIVinfected patients lack ex vivo HIV-suppressive capacity during acute and early infection
-
(doi:10.1371/journal.pone.0059767)
-
Lecuroux C et al. 2013 CD8 T-cells from most HIVinfected patients lack ex vivo HIV-suppressive capacity during acute and early infection. PLoS ONE 8, e59767. (doi:10.1371/journal.pone.0059767)
-
(2013)
PLoS ONE
, vol.8
-
-
Lecuroux, C.1
-
128
-
-
84868534523
-
Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection
-
(doi:10.1182/ blood-2012-04-422550)
-
Trautmann L et al. 2012 Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection. Blood 120, 3466-3477. (doi:10.1182/ blood-2012-04-422550)
-
(2012)
Blood
, vol.120
, pp. 3466-3477
-
-
Trautmann, L.1
-
129
-
-
84875520974
-
+ T cells
-
(doi:10.1016/j.immuni.2012.11.021)
-
+ T cells. Immunity 38, 425-436. (doi:10.1016/j.immuni.2012.11.021)
-
(2013)
Immunity
, vol.38
, pp. 425-436
-
-
Ladell, K.1
-
130
-
-
84862621390
-
TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection
-
(doi:10. 1038/ni.2342)
-
Chen H et al. 2012 TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection. Nat. Immunol. 13, 691-700. (doi:10. 1038/ni.2342)
-
(2012)
Nat. Immunol.
, vol.13
, pp. 691-700
-
-
Chen, H.1
-
131
-
-
80054721608
-
Dendritic cell dysfunction during primary HIV-1 infection
-
(doi:10.1093/infdis/jir616)
-
Huang J et al. 2011 Dendritic cell dysfunction during primary HIV-1 infection. J. Infect. Dis. 204, 1557-1562. (doi:10.1093/infdis/jir616)
-
(2011)
J. Infect. Dis.
, vol.204
, pp. 1557-1562
-
-
Huang, J.1
-
132
-
-
77956033397
-
Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers
-
(doi:10.1128/ JVI.01009-10)
-
Huang J, Burke PS, Cung TD, Pereyra F, Toth I, Walker BD, Borges L, Lichterfeld M, Yu XG. 2010 Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers. J. Virol. 84, 9463-9471. (doi:10.1128/ JVI.01009-10)
-
(2010)
J. Virol.
, vol.84
, pp. 9463-9471
-
-
Huang, J.1
Burke, P.S.2
Cung, T.D.3
Pereyra, F.4
Toth, I.5
Walker, B.D.6
Borges, L.7
Lichterfeld, M.8
Yu, X.G.9
-
133
-
-
43949124825
-
HLA class Irestricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control
-
(doi:10.1128/JVI.02176-07)
-
Emu B, Sinclair E, Hatano H, Ferre A, Shacklett B, Martin JN, McCune JM, Deeks SG. 2008 HLA class Irestricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J. Virol. 82, 5398-5407. (doi:10.1128/JVI.02176-07)
-
(2008)
J. Virol.
, vol.82
, pp. 5398-5407
-
-
Emu, B.1
Sinclair, E.2
Hatano, H.3
Ferre, A.4
Shacklett, B.5
Martin, J.N.6
McCune, J.M.7
Deeks, S.G.8
-
134
-
-
40049094957
-
Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy
-
(doi:10.1086/526786)
-
Pereyra F et al. 2008 Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy. J. Infect. Dis. 197, 563-571. (doi:10.1086/526786)
-
(2008)
J. Infect. Dis.
, vol.197
, pp. 563-571
-
-
Pereyra, F.1
-
135
-
-
84864020166
-
+ T cell responses maintain highly functional, broadly directed central memory responses
-
(doi:10.1128/ JVI.00531-12)
-
+ T cell responses maintain highly functional, broadly directed central memory responses. J. Virol. 86, 6959-6969. (doi:10.1128/ JVI.00531-12)
-
(2012)
J. Virol.
, vol.86
, pp. 6959-6969
-
-
Ndhlovu, Z.M.1
-
136
-
-
84863337769
-
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation
-
(doi:10.1016/j.immuni. 2012.01.014)
-
Shan L et al. 2012 Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity 36, 491-501. (doi:10.1016/j.immuni. 2012.01.014)
-
(2012)
Immunity
, vol.36
, pp. 491-501
-
-
Shan, L.1
-
137
-
-
0037007670
-
+ T cells
-
(doi:10. 1038/417095a)
-
+ T cells. Nature 417, 95-98. (doi:10. 1038/417095a)
-
(2002)
Nature
, vol.417
, pp. 95-98
-
-
Douek, D.C.1
-
138
-
-
73949119632
-
Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1
-
(doi:10.1073/pnas. 0907898106)
-
Benlahrech A et al. 2009 Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1. Proc. Natl Acad. Sci. USA 106, 19 940-19 945. (doi:10.1073/pnas. 0907898106)
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 19940-19945
-
-
Benlahrech, A.1
-
139
-
-
78650311033
-
Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine
-
(doi:10.1097/QAD.0b013e328 340fe55)
-
Papagno L et al. 2011 Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine. AIDS 25, 27-36. (doi:10.1097/QAD.0b013e328 340fe55)
-
(2011)
AIDS
, vol.25
, pp. 27-36
-
-
Papagno, L.1
-
140
-
-
84861173075
-
The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope
-
(doi:10.4049/jimmunol.1102756)
-
de Souza MS et al. 2012 The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope. J. Immunol. 188, 5166-5176. (doi:10.4049/jimmunol.1102756)
-
(2012)
J. Immunol.
, vol.188
, pp. 5166-5176
-
-
de Souza, M.S.1
-
141
-
-
84898726122
-
HIV-1 specific CD4 responses in primary HIV-1 infection predict disease progression in the SPARTAC trial
-
(doi:10. 1097/QAD.0000000000000130)
-
Frater J et al. 2014 HIV-1 specific CD4 responses in primary HIV-1 infection predict disease progression in the SPARTAC trial. AIDS 28, 699-708. (doi:10. 1097/QAD.0000000000000130)
-
(2014)
AIDS
, vol.28
, pp. 699-708
-
-
Frater, J.1
-
143
-
-
4644234449
-
+ T-cells: The holy grail?
-
(doi:10.1111/j.1365-2249.2004.02605.x)
-
+ T-cells: the holy grail? Clin. Exp. Immunol. 138, 10-13. (doi:10.1111/j.1365-2249.2004.02605.x)
-
(2004)
Clin. Exp. Immunol.
, vol.138
, pp. 10-13
-
-
Appay, V.1
-
144
-
-
84857751302
-
HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome
-
(doi:10.1126/scitranslmed.3003165)
-
Soghoian DZ et al. 2012 HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome. Sci. Transl. Med. 4, 123ra125. (doi:10.1126/scitranslmed.3003165)
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Soghoian, D.Z.1
-
145
-
-
0034724371
-
+ T lymphocytes
-
(doi:10.1073/ pnas.97.7.3382)
-
+ T lymphocytes. Proc. Natl Acad. Sci. USA 97, 3382-3387. (doi:10.1073/ pnas.97.7.3382)
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3382-3387
-
-
Oxenius, A.1
Price, D.A.2
Easterbrook, P.J.3
O'Callaghan, C.A.4
Kelleher, A.D.5
Whelan, J.A.6
Sontag, G.7
Sewell, A.K.8
Phillips, R.E.9
-
146
-
-
27644489746
-
Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment
-
(doi:10.1128/JVI.79.22.14169-14178.2005)
-
Emu B et al. 2005 Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment. J. Virol. 79, 14 169-14 178. (doi:10.1128/JVI.79.22.14169-14178.2005)
-
(2005)
J. Virol.
, vol.79
, pp. 14169-14178
-
-
Emu, B.1
-
147
-
-
37049027525
-
+ T-cell subsets in human immunodeficiency virus controllers: An ANRS EP36 study
-
(doi:10. 1128/JVI.01401-07)
-
+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study. J. Virol. 81, 13 904-13 915. (doi:10. 1128/JVI.01401-07)
-
(2007)
J. Virol.
, vol.81
, pp. 13904-13915
-
-
Potter, S.J.1
-
148
-
-
84869050052
-
HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term
-
(doi:10.1128/JVI. 00056-12)
-
Vingert B et al. 2012 HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term. J. Virol. 86, 10 661-10 674. (doi:10.1128/JVI. 00056-12)
-
(2012)
J. Virol.
, vol.86
, pp. 10661-10674
-
-
Vingert, B.1
-
149
-
-
34548680261
-
+ T cells correlates with disease progression and defines a reversible immune dysfunction
-
(doi:10. 1038/ni1515)
-
+ T cells correlates with disease progression and defines a reversible immune dysfunction. Nat. Immunol. 8, 1246-1254. (doi:10. 1038/ni1515)
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1246-1254
-
-
Kaufmann, D.E.1
-
150
-
-
40449085117
-
+) T cells during HIV infection
-
(doi:10.1038/nm1728)
-
+) T cells during HIV infection. Nat. Med. 14, 266-274. (doi:10.1038/nm1728)
-
(2008)
Nat. Med.
, vol.14
, pp. 266-274
-
-
van Grevenynghe, J.1
-
151
-
-
77649245149
-
+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity
-
(doi:10. 1371/journal.ppat.1000780)
-
+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity. PLoS Pathog. 6, e1000780. (doi:10. 1371/journal.ppat.1000780)
-
(2010)
PLoS Pathog.
, vol.6
-
-
Vingert, B.1
-
152
-
-
77957944425
-
+ T-cell responses
-
(doi:10.1128/JVI.00980-10)
-
+ T-cell responses. J. Virol. 84, 11 020-11 029. (doi:10.1128/JVI.00980-10)
-
(2010)
J. Virol.
, vol.84
, pp. 11020-11029
-
-
Ferre, A.L.1
-
153
-
-
84874519282
-
Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
-
(doi:10.1084/jem.20121932)
-
Perreau M, Savoye AL, De Crignis E, Corpataux JM, Cubas R, Haddad EK, De Leval L, Graziosi C, Pantaleo G. 2013 Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production. J. Exp. Med. 210, 143-156. (doi:10.1084/jem.20121932)
-
(2013)
J. Exp. Med.
, vol.210
, pp. 143-156
-
-
Perreau, M.1
Savoye, A.L.2
De Crignis, E.3
Corpataux, J.M.4
Cubas, R.5
Haddad, E.K.6
De Leval, L.7
Graziosi, C.8
Pantaleo, G.9
-
154
-
-
84875539507
-
Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques
-
(doi:10.1128/ JVI.02497-12)
-
Xu Y et al. 2013 Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J. Virol. 87, 3760-3773. (doi:10.1128/ JVI.02497-12)
-
(2013)
J. Virol.
, vol.87
, pp. 3760-3773
-
-
Xu, Y.1
-
155
-
-
84869814713
-
+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections
-
(doi:10.1182/blood-2012-06-437608)
-
+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections. Blood 120, 4172-4181. (doi:10.1182/blood-2012-06-437608)
-
(2012)
Blood
, vol.120
, pp. 4172-4181
-
-
Brenchley, J.M.1
Vinton, C.2
Tabb, B.3
Hao, X.P.4
Connick, E.5
Paiardini, M.6
Lifson, J.D.7
Silvestri, G.8
Estes, J.D.9
-
156
-
-
84859415408
-
+ T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape
-
(doi:10.4049/jimmunol.1103138)
-
+ T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape. J. Immunol. 188, 3247-3256. (doi:10.4049/jimmunol.1103138)
-
(2012)
J. Immunol.
, vol.188
, pp. 3247-3256
-
-
Hong, J.J.1
Amancha, P.K.2
Rogers, K.3
Ansari, A.A.4
Villinger, F.5
-
157
-
-
84865997747
-
Expansion of HIV-specific T follicular helper cells in chronic HIV infection
-
(doi:10.1172/JCI64314)
-
Lindqvist M et al. 2012 Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J. Clin. Invest. 122, 3271-3280. (doi:10.1172/JCI64314)
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3271-3280
-
-
Lindqvist, M.1
-
158
-
-
84865395104
-
CD4 T follicular helper cell dynamics during SIV infection
-
(doi:10.1172/JCI63039)
-
Petrovas C et al. 2012 CD4 T follicular helper cell dynamics during SIV infection. J. Clin. Invest. 122, 3281-3294. (doi:10.1172/JCI63039)
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3281-3294
-
-
Petrovas, C.1
-
159
-
-
84872093577
-
The split personality of regulatory T cells in HIV infection
-
(doi:10.1182/blood-2012-07-409755)
-
Chevalier MF, Weiss L. 2012 The split personality of regulatory T cells in HIV infection. Blood 121, 29-37. (doi:10.1182/blood-2012-07-409755)
-
(2012)
Blood
, vol.121
, pp. 29-37
-
-
Chevalier, M.F.1
Weiss, L.2
-
160
-
-
33750320502
-
+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART
-
(doi:10.1182/blood-2006-04-016923)
-
+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART. Blood 108, 3072-3078. (doi:10.1182/blood-2006-04-016923)
-
(2006)
Blood
, vol.108
, pp. 3072-3078
-
-
Epple Jr., H.1
-
161
-
-
76949087872
-
Th17 cells, HIV and the gut mucosal barrier
-
(doi:10.1097/COH. 0b013e328335eda3)
-
Dandekar S, George MD, Baumler AJ. 2010 Th17 cells, HIV and the gut mucosal barrier. Curr. Opin. HIV AIDS 5, 173-178. (doi:10.1097/COH. 0b013e328335eda3)
-
(2010)
Curr. Opin. HIV AIDS
, vol.5
, pp. 173-178
-
-
Dandekar, S.1
George, M.D.2
Baumler, A.J.3
-
162
-
-
84860359331
-
Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue
-
(doi:10.1093/infdis/jis236)
-
Angin M et al. 2012 Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue. J. Infect. Dis. 205, 1495-1500. (doi:10.1093/infdis/jis236)
-
(2012)
J. Infect. Dis.
, vol.205
, pp. 1495-1500
-
-
Angin, M.1
-
163
-
-
79551649723
-
A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers
-
(doi:10.1371/journal.pone. 0015924)
-
Hunt PW et al. 2011 A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers. PLoS ONE 6, e15924. (doi:10.1371/journal.pone. 0015924)
-
(2011)
PLoS ONE
, vol.6
-
-
Hunt, P.W.1
-
164
-
-
77951877224
-
+ elite controllers have low HIVspecific T-cell activation yet maintain strong, polyfunctional T-cell responses
-
(doi:10.1097/QAD.0b013e3283377a1e)
-
+ elite controllers have low HIVspecific T-cell activation yet maintain strong, polyfunctional T-cell responses. AIDS 24, 1095-1105. (doi:10.1097/QAD.0b013e3283377a1e)
-
(2010)
AIDS
, vol.24
, pp. 1095-1105
-
-
Owen, R.E.1
Heitman, J.W.2
Hirschkorn, D.F.3
Lanteri, M.C.4
Biswas, H.H.5
Martin, J.N.6
Krone, M.R.7
Deeks, S.G.8
Norris, P.J.9
-
165
-
-
84860372550
-
Early and long-lasting alteration of effector CD45RA-Foxp3high regulatory T-cell homeostasis during HIV infection
-
(doi:10.1093/infdis/jis235)
-
Simonetta F, Lecuroux C, Girault I, Goujard C, Sinet M, Lambotte O, Venet A, Bourgeois C. 2012 Early and long-lasting alteration of effector CD45RA-Foxp3high regulatory T-cell homeostasis during HIV infection. J. Infect. Dis. 205, 1510-1519. (doi:10.1093/infdis/jis235)
-
(2012)
J. Infect. Dis.
, vol.205
, pp. 1510-1519
-
-
Simonetta, F.1
Lecuroux, C.2
Girault, I.3
Goujard, C.4
Sinet, M.5
Lambotte, O.6
Venet, A.7
Bourgeois, C.8
-
166
-
-
79961160736
-
+ T cells evade Treg cell suppression
-
(doi:10.1038/ nm.2422)
-
+ T cells evade Treg cell suppression. Nat. Med. 17, 989-995. (doi:10.1038/ nm.2422)
-
(2011)
Nat. Med.
, vol.17
, pp. 989-995
-
-
Elahi, S.1
Dinges, W.L.2
Lejarcegui, N.3
Laing, K.J.4
Collier, A.C.5
Koelle, D.M.6
McElrath, M.J.7
Horton, H.8
-
167
-
-
84860153884
-
The antibody response against HIV-1
-
(doi:10.1101/cshperspect.a007039)
-
Overbaugh J, Morris L. 2012 The antibody response against HIV-1. Cold Spring Harb. Perspect. Med. 2, a007039. (doi:10.1101/cshperspect.a007039)
-
(2012)
Cold Spring Harb. Perspect. Med.
, vol.2
-
-
Overbaugh, J.1
Morris, L.2
-
168
-
-
67650453747
-
Human immunodeficiency virus type 1 elite neutralizers: Individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
-
(doi:10.1128/JVI.00110-09)
-
Simek MD et al. 2009 Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. J. Virol. 83, 7337-7348. (doi:10.1128/JVI.00110-09)
-
(2009)
J. Virol.
, vol.83
, pp. 7337-7348
-
-
Simek, M.D.1
-
169
-
-
84887626950
-
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys
-
(doi:10.1038/nature12744)
-
Barouch DH et al. 2013 Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys. Nature 503, 224-228. (doi:10.1038/nature12744)
-
(2013)
Nature
, vol.503
, pp. 224-228
-
-
Barouch, D.H.1
-
170
-
-
34347206841
-
Mucosal immune responses in the genital tract of HIV-1-exposed uninfected women
-
(doi:10.1111/j.1365-2796.2007.01822.x)
-
Hirbod T, Broliden K. 2007 Mucosal immune responses in the genital tract of HIV-1-exposed uninfected women. J. Intern. Med. 262, 44-58. (doi:10.1111/j.1365-2796.2007.01822.x).
-
(2007)
J. Intern. Med.
, vol.262
, pp. 44-58
-
-
Hirbod, T.1
Broliden, K.2
-
171
-
-
0032989686
-
HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers
-
(doi:10.1097/00002030-199901140-00004)
-
Kaul R et al. 1999 HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers. AIDS 13, 23-29. (doi:10.1097/00002030-199901140-00004)
-
(1999)
AIDS
, vol.13
, pp. 23-29
-
-
Kaul, R.1
-
172
-
-
0034766611
-
HIV type 1-specific IgG2 antibodies: Markers of helper T cell type 1 response and prognostic marker of long-term nonprogression
-
(doi:10.1089/088922201753197105)
-
Ngo-Giang-Huong N et al. 2001 HIV type 1-specific IgG2 antibodies: markers of helper T cell type 1 response and prognostic marker of long-term nonprogression. AIDS Res. Hum. Retroviruses 17, 1435-1446. (doi:10.1089/088922201753197105)
-
(2001)
AIDS Res. Hum. Retroviruses
, vol.17
, pp. 1435-1446
-
-
Ngo-Giang-Huong, N.1
-
173
-
-
84873395169
-
Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to 'protective' human leukocyte antigen-B alleles in HIV controllers
-
(doi:10.1097/QAD.0b013e32835cb720)
-
French MA et al. 2013 Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to 'protective' human leukocyte antigen-B alleles in HIV controllers. AIDS 27, 519-528. (doi:10.1097/QAD.0b013e32835cb720)
-
(2013)
AIDS
, vol.27
, pp. 519-528
-
-
French, M.A.1
-
174
-
-
84896730604
-
Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers
-
(doi:10.1128/ JVI.03130-13)
-
Lai JI, Licht AF, Dugast AS, Suscovich T, Choi I, Bailey-Kellogg C, Alter G, Ackerman ME. 2013 Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers. J. Virol. 88, 2799-2809. (doi:10.1128/ JVI.03130-13)
-
(2013)
J. Virol.
, vol.88
, pp. 2799-2809
-
-
Lai, J.I.1
Licht, A.F.2
Dugast, A.S.3
Suscovich, T.4
Choi, I.5
Bailey-Kellogg, C.6
Alter, G.7
Ackerman, M.E.8
-
175
-
-
67149120819
-
Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers
-
(doi:10.1097/QAD.0b013e328329f97d)
-
Lambotte O et al. 2009 Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers. AIDS 23, 897-906. (doi:10.1097/QAD.0b013e328329f97d)
-
(2009)
AIDS
, vol.23
, pp. 897-906
-
-
Lambotte, O.1
-
176
-
-
84862798995
-
Epistatic interactions between Fc (GM) and FcgR genes and the host control of human immunodeficiency virus replication
-
(doi:10.1016/j.humimm. 2011.12.008)
-
Deepe RN, Kistner-Griffin E, Martin JN, Deeks SG, Pandey JP. 2012 Epistatic interactions between Fc (GM) and FcgR genes and the host control of human immunodeficiency virus replication. Hum. Immunol. 73, 263-266. (doi:10.1016/j.humimm. 2011.12.008)
-
(2012)
Hum. Immunol.
, vol.73
, pp. 263-266
-
-
Deepe, R.N.1
Kistner-Griffin, E.2
Martin, J.N.3
Deeks, S.G.4
Pandey, J.P.5
-
177
-
-
69249213610
-
Matrix metalloprotease inhibitors restore impaired NK cellmediated antibody-dependent cellular cytotoxicity in human immunodeficiency virus type 1 infection
-
(doi:10.1128/JVI.02666-08)
-
Liu Q, Sun Y, Rihn S, Nolting A, Tsoukas PN, Jost S, Cohen K, Walker B, Alter G. 2009 Matrix metalloprotease inhibitors restore impaired NK cellmediated antibody-dependent cellular cytotoxicity in human immunodeficiency virus type 1 infection. J. Virol. 83, 8705-8712. (doi:10.1128/JVI.02666-08)
-
(2009)
J. Virol.
, vol.83
, pp. 8705-8712
-
-
Liu, Q.1
Sun, Y.2
Rihn, S.3
Nolting, A.4
Tsoukas, P.N.5
Jost, S.6
Cohen, K.7
Walker, B.8
Alter, G.9
-
178
-
-
84867902474
-
Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family
-
(doi:10.1128/JVI.01023-12)
-
Bonsignori M et al. 2012 Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family. J. Virol. 86, 11 521-11 532. (doi:10.1128/JVI.01023-12)
-
(2012)
J. Virol.
, vol.86
, pp. 11521-11532
-
-
Bonsignori, M.1
-
179
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
-
(doi:10.1056/ NEJMoa0908492)
-
Rerks-Ngarm S et al. 2009 Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 361, 2209-2220. (doi:10.1056/ NEJMoa0908492)
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2209-2220
-
-
Rerks-Ngarm, S.1
-
180
-
-
84885761187
-
p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway
-
(doi:10.1073/ pnas.1306719110)
-
Allouch A et al. 2013 p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway. Proc. Natl Acad. Sci. USA 110, E3997-E4006. (doi:10.1073/ pnas.1306719110)
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
-
-
Allouch, A.1
-
181
-
-
44649140372
-
Complement-HIV interactions during all steps of viral pathogenesis
-
(doi:10.1016/j.vaccine.2007.12.003)
-
Stoiber H, Banki Z, Wilflingseder D, Dierich MP. 2008 Complement-HIV interactions during all steps of viral pathogenesis. Vaccine 26, 3046-3054. (doi:10.1016/j.vaccine.2007.12.003)
-
(2008)
Vaccine
, vol.26
, pp. 3046-3054
-
-
Stoiber, H.1
Banki, Z.2
Wilflingseder, D.3
Dierich, M.P.4
-
182
-
-
77954082267
-
Complement as an endogenous adjuvant for dendritic cell-mediated induction of retrovirus-specific CTLs
-
(doi:10.1371/journal.ppat.1000891)
-
Banki Z et al. 2010 Complement as an endogenous adjuvant for dendritic cell-mediated induction of retrovirus-specific CTLs. PLoS Pathog. 6, e1000891. (doi:10.1371/journal.ppat.1000891)
-
(2010)
PLoS Pathog.
, vol.6
-
-
Banki, Z.1
-
183
-
-
84870291347
-
Antibodies attenuate the capacity of dendritic cells to stimulate HIVspecific cytotoxic T lymphocytes
-
(doi:10.1016/j.jaci. 2012.08.025)
-
Posch W et al. 2012 Antibodies attenuate the capacity of dendritic cells to stimulate HIVspecific cytotoxic T lymphocytes. J. Allergy Clin. Immunol. 130, 1368-1374. (doi:10.1016/j.jaci. 2012.08.025)
-
(2012)
J. Allergy Clin. Immunol.
, vol.130
, pp. 1368-1374
-
-
Posch, W.1
-
184
-
-
84865171842
-
Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates
-
(doi:10.1182/ blood-2012-03-414706)
-
Pandrea I et al. 2012 Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates. Blood 120, 1357-1366. (doi:10.1182/ blood-2012-03-414706)
-
(2012)
Blood
, vol.120
, pp. 1357-1366
-
-
Pandrea, I.1
-
185
-
-
43949088825
-
Plasmacytoid dendritic cell dynamics and alpha interferon production during simian immunodeficiency virus infection with a nonpathogenic outcome
-
(doi:10.1128/JVI.02433-07)
-
Diop OM et al. 2008 Plasmacytoid dendritic cell dynamics and alpha interferon production during simian immunodeficiency virus infection with a nonpathogenic outcome. J. Virol. 82, 5145-5152. (doi:10.1128/JVI.02433-07)
-
(2008)
J. Virol.
, vol.82
, pp. 5145-5152
-
-
Diop, O.M.1
-
186
-
-
84887309874
-
Kinetics of myeloid dendritic cell trafficking and activation: Impact on progressive, nonprogressive and controlled SIV infections
-
(doi:10.1371/ journal.ppat.1003600)
-
Wijewardana V et al. 2013 Kinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infections. PLoS Pathog. 9, e1003600. (doi:10.1371/ journal.ppat.1003600)
-
(2013)
PLoS Pathog.
, vol.9
-
-
Wijewardana, V.1
-
187
-
-
55049083095
-
Sooty mangabeys and rhesus macaques exhibit significant divergent natural killer cell responses during both acute and chronic phases of SIV infection
-
(doi:10.1016/j.cellimm.2008.06.006)
-
Pereira LE, Johnson RP, Ansari AA. 2008 Sooty mangabeys and rhesus macaques exhibit significant divergent natural killer cell responses during both acute and chronic phases of SIV infection. Cell. Immunol. 254, 10-19. (doi:10.1016/j.cellimm.2008.06.006)
-
(2008)
Cell. Immunol.
, vol.254
, pp. 10-19
-
-
Pereira, L.E.1
Johnson, R.P.2
Ansari, A.A.3
-
188
-
-
84883365277
-
Intact type i interferon production and IRF7 function in sooty mangabeys
-
(doi:10.1371/journal. ppat.1003597)
-
Bosinger SE et al. 2013 Intact type i interferon production and IRF7 function in sooty mangabeys. PLoS Pathog. 9, e1003597. (doi:10.1371/journal. ppat.1003597)
-
(2013)
PLoS Pathog.
, vol.9
-
-
Bosinger, S.E.1
-
189
-
-
72849136282
-
Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response
-
(doi:10.1172/JCI40093)
-
Jacquelin B et al. 2009 Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response. J. Clin. Invest. 119, 3544-3555. (doi:10.1172/JCI40093)
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3544-3555
-
-
Jacquelin, B.1
-
190
-
-
84882895090
-
Natural SIV infection: Immunological aspects
-
(eds G Pancino, G Silvestri, K Fowke), San Diego, CA: Academic Press
-
Jacquelin B, Zahn RC, Barré-Sinoussi F, Schmitz JE, Kaur A, Müller-Trutwin MC. 2011 Natural SIV infection: immunological aspects. In Models of protection against HIV/SIV: avoiding AIDS in humans and monkeys (eds G Pancino, G Silvestri, K Fowke), pp. 47-80. San Diego, CA: Academic Press.
-
(2011)
Models of protection against HIV/SIV: Avoiding AIDS in humans and monkeys
, pp. 47-80
-
-
Jacquelin, B.1
Zahn, R.C.2
Barré-Sinoussi, F.3
Schmitz, J.E.4
Kaur, A.5
Müller-Trutwin, M.C.6
-
191
-
-
84860255621
-
Immune responses driven by protective human leukocyte antigen alleles from long-term nonprogressors are associated with low HIV reservoir in central memory CD4 T cells
-
(doi:10.1093/cid/cis188)
-
Descours B et al. 2012 Immune responses driven by protective human leukocyte antigen alleles from long-term nonprogressors are associated with low HIV reservoir in central memory CD4 T cells. Clin. Infect. Dis. 54, 1495-1503. (doi:10.1093/cid/cis188)
-
(2012)
Clin. Infect. Dis.
, vol.54
, pp. 1495-1503
-
-
Descours, B.1
-
192
-
-
34547752932
-
Low immune activation despite high levels of pathogenic human immunodeficiency virus type 1 results in long-term asymptomatic disease
-
(doi:10.1128/JVI.02663-06)
-
Choudhary SK, Vrisekoop N, Jansen CA, Otto SA, Schuitemaker H, Miedema F, Camerini D. 2007 Low immune activation despite high levels of pathogenic human immunodeficiency virus type 1 results in long-term asymptomatic disease. J. Virol. 81, 8838-8842. (doi:10.1128/JVI.02663-06)
-
(2007)
J. Virol.
, vol.81
, pp. 8838-8842
-
-
Choudhary, S.K.1
Vrisekoop, N.2
Jansen, C.A.3
Otto, S.A.4
Schuitemaker, H.5
Miedema, F.6
Camerini, D.7
-
193
-
-
39349088126
-
+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy
-
(doi:10.1086/524143)
-
+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J. Infect. Dis. 197, 126-133. (doi:10.1086/524143)
-
(2008)
J. Infect. Dis.
, vol.197
, pp. 126-133
-
-
Hunt, P.W.1
-
194
-
-
67651125105
-
Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis
-
(doi:10.1097/QAD. 0b013e32832b514b)
-
Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG. 2009 Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis. AIDS 23, 1059-1067. (doi:10.1097/QAD. 0b013e32832b514b)
-
(2009)
AIDS
, vol.23
, pp. 1059-1067
-
-
Hsue, P.Y.1
Hunt, P.W.2
Schnell, A.3
Kalapus, S.C.4
Hoh, R.5
Ganz, P.6
Martin, J.N.7
Deeks, S.G.8
-
195
-
-
84870251319
-
Increased coronary atherosclerosis and immune activation in HIV-1 elite controllers
-
(doi:10.1097/ QAD.0b013e32835a9950)
-
Pereyra F et al. 2012 Increased coronary atherosclerosis and immune activation in HIV-1 elite controllers. AIDS 26, 2409-2412. (doi:10.1097/ QAD.0b013e32835a9950)
-
(2012)
AIDS
, vol.26
, pp. 2409-2412
-
-
Pereyra, F.1
-
196
-
-
84895726096
-
Evidence for innate immune system activation in HIV Type 1-infected elite controllers
-
(doi:10.1093/infdis/ jit581)
-
Krishnan S, Wilson EM, Sheikh V, Rupert A, Mendoza D, Yang J, Lempicki R, Migueles SA, Sereti I. 2013 Evidence for innate immune system activation in HIV Type 1-infected elite controllers. J. Infect. Dis. 209, 931-939. (doi:10.1093/infdis/ jit581)
-
(2013)
J. Infect. Dis.
, vol.209
, pp. 931-939
-
-
Krishnan, S.1
Wilson, E.M.2
Sheikh, V.3
Rupert, A.4
Mendoza, D.5
Yang, J.6
Lempicki, R.7
Migueles, S.A.8
Sereti, I.9
-
197
-
-
84895070040
-
+ T-cell counts in HIV controller patients
-
(doi:10.1097/QAD.0000000000000174)
-
+ T-cell counts in HIV controller patients. AIDS 28, 467-476. (doi:10.1097/QAD.0000000000000174)
-
(2013)
AIDS
, vol.28
, pp. 467-476
-
-
Noel, N.1
-
198
-
-
58149382617
-
Evidence for persistent lowlevel viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy
-
(doi:10.1128/JVI.01763-08)
-
Hatano H et al. 2009 Evidence for persistent lowlevel viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy. J. Virol. 83, 329-335. (doi:10.1128/JVI.01763-08)
-
(2009)
J. Virol.
, vol.83
, pp. 329-335
-
-
Hatano, H.1
-
199
-
-
79955420643
-
CD4 dynamics over a 15 yearperiod among HIV controllers enrolled in the ANRS French observatory
-
(doi:10. 1371/journal.pone.0018726)
-
Boufassa F et al. 2011 CD4 dynamics over a 15 yearperiod among HIV controllers enrolled in the ANRS French observatory. PLoS ONE 6, e18726. (doi:10. 1371/journal.pone.0018726)
-
(2011)
PLoS ONE
, vol.6
-
-
Boufassa, F.1
-
200
-
-
79952408305
-
Transcriptional profiling of CD4 T cells identifies distinct subgroups of HIV-1 elite controllers
-
(doi:10. 1128/JVI.01846-10)
-
Vigneault F et al. 2011 Transcriptional profiling of CD4 T cells identifies distinct subgroups of HIV-1 elite controllers. J. Virol. 85, 3015-3019. (doi:10. 1128/JVI.01846-10)
-
(2011)
J. Virol.
, vol.85
, pp. 3015-3019
-
-
Vigneault, F.1
-
201
-
-
85020718320
-
+ T cell responses restrict SIV replication to follicular helper T cells
-
Atlanta, GA, USA, 3-6 November 2013
-
+ T cell responses restrict SIV replication to follicular helper T cells. In 31st Annual Symp. on Nonhuman Primate Models for AIDS. Atlanta, GA, USA, 3-6 November 2013.
-
(2013)
31st Annual Symp. on Nonhuman Primate Models for AIDS
-
-
Fukazawa, Y.1
-
202
-
-
0025024923
-
Lymphatic tissue changes in AIDS and other retrovirus infections: Tools and insights
-
Racz P, Tenner-Racz K, van Vloten F, Schmidt H, Dietrich M, Gluckman JC, Letvin NL, Janossy G. 1990 Lymphatic tissue changes in AIDS and other retrovirus infections: tools and insights. Lymphology 23, 85-91.
-
(1990)
Lymphology
, vol.23
, pp. 85-91
-
-
Racz, P.1
Tenner-Racz, K.2
van Vloten, F.3
Schmidt, H.4
Dietrich, M.5
Gluckman, J.C.6
Letvin, N.L.7
Janossy, G.8
-
203
-
-
58149177783
-
+ T cell depletion
-
+ T cell depletion. J. Immunol. 181, 6687-6691.
-
(2008)
J. Immunol.
, vol.181
, pp. 6687-6691
-
-
Pandrea, I.1
-
204
-
-
84897965706
-
HIV cure research: Advances and prospects
-
In press, (doi:10. 1016/j.virol.2014.02.021)
-
Passaes CP, Saez-Cirion A. In press. HIV cure research: advances and prospects. Virology. (doi:10. 1016/j.virol.2014.02.021)
-
Virology
-
-
Passaes, C.P.1
Saez-Cirion, A.2
-
205
-
-
84887028999
-
Absence of detectable HIV-1 viremia after treatment cessation in an infant
-
(doi:10.1056/NEJMoa1302976)
-
Persaud D, Gay H, Ziemniak C, Chen YH, Piatak Jr M, Chun TW, Strain M, Richman D, Luzuriaga K. 2013 Absence of detectable HIV-1 viremia after treatment cessation in an infant. N. Engl. J. Med. 369, 1828-1835. (doi:10.1056/NEJMoa1302976)
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 1828-1835
-
-
Persaud, D.1
Gay, H.2
Ziemniak, C.3
Chen, Y.H.4
Piatak Jr., M.5
Chun, T.W.6
Strain, M.7
Richman, D.8
Luzuriaga, K.9
-
206
-
-
0035853422
-
Proviral HIV-1 DNA in subjects followed since primary HIV-1 infection who suppress plasma viral load after one year of highly active antiretroviral therapy
-
(doi:10.1097/00002030-200104130-00001)
-
Ngo-Giang-Huong N et al. 2001 Proviral HIV-1 DNA in subjects followed since primary HIV-1 infection who suppress plasma viral load after one year of highly active antiretroviral therapy. AIDS 15, 665-673. (doi:10.1097/00002030-200104130-00001)
-
(2001)
AIDS
, vol.15
, pp. 665-673
-
-
Ngo-Giang-Huong, N.1
-
207
-
-
0037169213
-
Homogeneous quasispecies in 16 out of 17 individuals during very early HIV-1 primary infection
-
(doi:10.1097/ 00002030-200201250-00007)
-
Delwart E, Magierowska M, Royz M, Foley B, Peddada L, Smith R, Heldebrant C, Conrad A, Busch M. 2002 Homogeneous quasispecies in 16 out of 17 individuals during very early HIV-1 primary infection. AIDS 16, 189-195. (doi:10.1097/ 00002030-200201250-00007)
-
(2002)
AIDS
, vol.16
, pp. 189-195
-
-
Delwart, E.1
Magierowska, M.2
Royz, M.3
Foley, B.4
Peddada, L.5
Smith, R.6
Heldebrant, C.7
Conrad, A.8
Busch, M.9
-
208
-
-
78650440267
-
B cells in early and chronic HIV infection: Evidence for preservation of immune function associated with early initiation of antiretroviral therapy
-
(doi:10.1182/blood-2010-05-285528)
-
Moir S et al. 2010 B cells in early and chronic HIV infection: evidence for preservation of immune function associated with early initiation of antiretroviral therapy. Blood 116, 5571-5579. (doi:10.1182/blood-2010-05-285528)
-
(2010)
Blood
, vol.116
, pp. 5571-5579
-
-
Moir, S.1
-
209
-
-
59649116097
-
IL-2, IL-7 and IL-15 as immuno-modulators during SIV/HIV vaccination and treatment
-
(doi:10.2174/157016209787048519)
-
Leone A, Picker LJ, Sodora DL. 2009 IL-2, IL-7 and IL-15 as immuno-modulators during SIV/HIV vaccination and treatment. Curr. HIV Res. 7, 83-90. (doi:10.2174/157016209787048519)
-
(2009)
Curr. HIV Res.
, vol.7
, pp. 83-90
-
-
Leone, A.1
Picker, L.J.2
Sodora, D.L.3
-
210
-
-
65249105408
-
Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment
-
(doi:10.1172/JCI38052)
-
Levy Y et al. 2009 Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment. J. Clin. Invest. 119, 997-1007. (doi:10.1172/JCI38052)
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 997-1007
-
-
Levy, Y.1
-
211
-
-
84864125153
-
Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: Results of a phase I/IIa randomized, placebo-controlled, multicenter study
-
(doi:10.1093/cid/cis383)
-
Levy Y et al. 2012 Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study. Clin. Infect. Dis. 55, 291-300. (doi:10.1093/cid/cis383)
-
(2012)
Clin. Infect. Dis.
, vol.55
, pp. 291-300
-
-
Levy, Y.1
-
212
-
-
84879302206
-
Interleukin-7 promotes HIV persistence during antiretroviral therapy
-
(doi:10.1182/blood-2012-11-465625)
-
Vandergeeten C et al. 2013 Interleukin-7 promotes HIV persistence during antiretroviral therapy. Blood 121, 4321-4329. (doi:10.1182/blood-2012-11-465625)
-
(2013)
Blood
, vol.121
, pp. 4321-4329
-
-
Vandergeeten, C.1
-
213
-
-
77951889263
-
Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: A phase II clinical trial
-
(doi:10.1086/652420)
-
Asmuth DM et al. 2010 Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trial. J. Infect. Dis. 201, 1686-1696. (doi:10.1086/652420)
-
(2010)
J. Infect. Dis.
, vol.201
, pp. 1686-1696
-
-
Asmuth, D.M.1
-
214
-
-
84871797372
-
Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration
-
(doi:10. 1093/infdis/jis663)
-
Azzoni L et al. 2013 Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration. J. Infect. Dis. 207, 213-222. (doi:10. 1093/infdis/jis663)
-
(2013)
J. Infect. Dis.
, vol.207
, pp. 213-222
-
-
Azzoni, L.1
-
215
-
-
78650307734
-
Alpha interferon administration during structured interruptions of combination antiretroviral therapy in patients with chronic HIV-1 infection: INTERVAC ANRS 105 trial
-
(doi:10.1097/ QAD.0b013e328340a1e7)
-
Boue F, Reynes J, Rouzioux C, Emilie D, Souala F, Tubiana R, Goujard C, Lancar R, Costagliola D. 2011 Alpha interferon administration during structured interruptions of combination antiretroviral therapy in patients with chronic HIV-1 infection: INTERVAC ANRS 105 trial. AIDS 25, 115-118. (doi:10.1097/ QAD.0b013e328340a1e7)
-
(2011)
AIDS
, vol.25
, pp. 115-118
-
-
Boue, F.1
Reynes, J.2
Rouzioux, C.3
Emilie, D.4
Souala, F.5
Tubiana, R.6
Goujard, C.7
Lancar, R.8
Costagliola, D.9
-
216
-
-
84858986741
-
Role of PD-1 in HIV pathogenesis and as target for therapy
-
(doi:10.1007/s11904-011-0106-4)
-
Porichis F, Kaufmann DE. 2012 Role of PD-1 in HIV pathogenesis and as target for therapy. Curr. HIV/ AIDS Rep. 9, 81-90. (doi:10.1007/s11904-011-0106-4)
-
(2012)
Curr. HIV/ AIDS Rep.
, vol.9
, pp. 81-90
-
-
Porichis, F.1
Kaufmann, D.E.2
-
217
-
-
62249172189
-
Enhancing SIV-specific immunity in vivo by PD-1 blockade
-
(doi:10.1038/nature07662)
-
Velu V et al. 2009 Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 458, 206-210. (doi:10.1038/nature07662)
-
(2009)
Nature
, vol.458
, pp. 206-210
-
-
Velu, V.1
-
218
-
-
85020692119
-
PD-1 blockade as an adjunct therapy for ART: Improves anti-SIV immunity, virologic response to ART and gut CD4 T cell restoration
-
Atlanta, GA, USA, 3-6 November 2013
-
Velu V, Mylvaganam G, Freeman G, Ahmed R, Amara R. 2013 PD-1 blockade as an adjunct therapy for ART: improves anti-SIV immunity, virologic response to ART and gut CD4 T cell restoration. In 31st Annual Symp. on Nonhuman Primate Models for AIDS, Atlanta, GA, USA, 3-6 November 2013.
-
(2013)
31st Annual Symp. on Nonhuman Primate Models for AIDS
-
-
Velu, V.1
Mylvaganam, G.2
Freeman, G.3
Ahmed, R.4
Amara, R.5
-
219
-
-
68349139711
-
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
-
(doi:10.1038/nm.1972)
-
Chomont N et al. 2009 HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat. Med. 15, 893-900. (doi:10.1038/nm.1972)
-
(2009)
Nat. Med.
, vol.15
, pp. 893-900
-
-
Chomont, N.1
-
220
-
-
84860584561
-
PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques
-
(doi:10.1172/JCI60612)
-
Dyavar Shetty R, Velu V, Titanji K, Bosinger SE, Freeman GJ, Silvestri G, Amara RR. 2012 PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques. J. Clin. Invest. 122, 1712-1716. (doi:10.1172/JCI60612)
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1712-1716
-
-
Dyavar Shetty, R.1
Velu, V.2
Titanji, K.3
Bosinger, S.E.4
Freeman, G.J.5
Silvestri, G.6
Amara, R.R.7
-
221
-
-
84876420618
-
Immune activation and HIV persistence: Considerations for novel therapeutic interventions
-
(doi:10.1097/COH.0b013e32835f9788)
-
Hatano H. 2013 Immune activation and HIV persistence: considerations for novel therapeutic interventions. Curr. Opin. HIV AIDS 8, 211-216. (doi:10.1097/COH.0b013e32835f9788)
-
(2013)
Curr. Opin. HIV AIDS
, vol.8
, pp. 211-216
-
-
Hatano, H.1
-
222
-
-
0030663246
-
Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1
-
(doi:10.1016/S0149-2918(97)80045-8)
-
Sperber K, Chiang G, Chen H, Ross W, Chusid E, Gonchar M, Chow R, Liriano O. 1997 Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1. Clin. Ther. 19, 913-923. (doi:10.1016/S0149-2918(97)80045-8)
-
(1997)
Clin. Ther.
, vol.19
, pp. 913-923
-
-
Sperber, K.1
Chiang, G.2
Chen, H.3
Ross, W.4
Chusid, E.5
Gonchar, M.6
Chow, R.7
Liriano, O.8
-
223
-
-
0029121276
-
Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1
-
(doi:10.1016/ 0149-2918(95)80039-5)
-
Sperber K, Louie M, Kraus T, Proner J, Sapira E, Lin S, Stecher V, Mayer L. 1995 Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1. Clin. Ther. 17, 622-636. (doi:10.1016/ 0149-2918(95)80039-5)
-
(1995)
Clin. Ther.
, vol.17
, pp. 622-636
-
-
Sperber, K.1
Louie, M.2
Kraus, T.3
Proner, J.4
Sapira, E.5
Lin, S.6
Stecher, V.7
Mayer, L.8
-
224
-
-
75749126515
-
Chloroquine modulates HIV-1-induced plasmacytoid dendritic cell alpha interferon: Implication for T-cell activation
-
(doi:10.1128/AAC.01246-09)
-
Martinson JA, Montoya CJ, Usuga X, Ronquillo R, Landay AL, Desai SN. 2010 Chloroquine modulates HIV-1-induced plasmacytoid dendritic cell alpha interferon: implication for T-cell activation. Antimicrob. Agents Chemother. 54, 871-881. (doi:10.1128/AAC.01246-09)
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 871-881
-
-
Martinson, J.A.1
Montoya, C.J.2
Usuga, X.3
Ronquillo, R.4
Landay, A.L.5
Desai, S.N.6
-
225
-
-
78049505077
-
Reduction of immune activation with chloroquine therapy during chronic HIV infection
-
(doi:10.1128/JVI. 01466-10)
-
Murray SM, Down CM, Boulware DR, Stauffer WM, Cavert WP, Schacker TW, Brenchley JM, Douek DC. 2010 Reduction of immune activation with chloroquine therapy during chronic HIV infection. J. Virol. 84, 12 082-12 086. (doi:10.1128/JVI. 01466-10)
-
(2010)
J. Virol.
, vol.84
, pp. 12082-12086
-
-
Murray, S.M.1
Down, C.M.2
Boulware, D.R.3
Stauffer, W.M.4
Cavert, W.P.5
Schacker, T.W.6
Brenchley, J.M.7
Douek, D.C.8
-
226
-
-
84864149976
-
Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: A randomized controlled trial
-
(doi:10.1001/jama.2012.6936)
-
Paton NI et al. 2012 Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: a randomized controlled trial. JAMA 308, 353-361. (doi:10.1001/jama.2012.6936)
-
(2012)
JAMA
, vol.308
, pp. 353-361
-
-
Paton, N.I.1
-
227
-
-
84893332288
-
Rosuvastatin treatment reduces markers of monocyte activation in HIV-infected subjects on antiretroviral therapy
-
(doi:10.1093/cid/cit748)
-
Funderburg NT, Jiang Y, Debanne SM, Storer N, Labbato D, Clagett B, Robinson J, Lederman MM, McComsey GA. 2013 Rosuvastatin treatment reduces markers of monocyte activation in HIV-infected subjects on antiretroviral therapy. Clin. Infect. Dis. 58, 588-596. (doi:10.1093/cid/cit748)
-
(2013)
Clin. Infect. Dis.
, vol.58
, pp. 588-596
-
-
Funderburg, N.T.1
Jiang, Y.2
Debanne, S.M.3
Storer, N.4
Labbato, D.5
Clagett, B.6
Robinson, J.7
Lederman, M.M.8
McComsey, G.A.9
-
228
-
-
84877252239
-
Effect of statin therapy in reducing the risk of serious non-AIDS-defining events and nonaccidental death
-
(doi:10.1093/cid/cit053)
-
Overton ET, Kitch D, Benson CA, Hunt PW, Stein JH, Smurzynski M, Ribaudo HJ, Tebas P. 2013 Effect of statin therapy in reducing the risk of serious non-AIDS-defining events and nonaccidental death. Clin. Infect. Dis 56, 1471-1479. (doi:10.1093/cid/cit053)
-
(2013)
Clin. Infect. Dis
, vol.56
, pp. 1471-1479
-
-
Overton, E.T.1
Kitch, D.2
Benson, C.A.3
Hunt, P.W.4
Stein, J.H.5
Smurzynski, M.6
Ribaudo, H.J.7
Tebas, P.8
-
229
-
-
84874739728
-
Statin therapy and mortality in HIV-infected individuals; a Danish nationwide population-based cohort study
-
(doi:10.1371/journal.pone.0052828)
-
Rasmussen LD, Kronborg G, Larsen CS, Pedersen C, Gerstoft J, Obel N. 2013 Statin therapy and mortality in HIV-infected individuals; a Danish nationwide population-based cohort study. PLoS ONE 8, e52828. (doi:10.1371/journal.pone.0052828)
-
(2013)
PLoS ONE
, vol.8
-
-
Rasmussen, L.D.1
Kronborg, G.2
Larsen, C.S.3
Pedersen, C.4
Gerstoft, J.5
Obel, N.6
-
230
-
-
84922462830
-
Statin use is associated with incident diabetes mellitus among patients in the HIV outpatient study
-
Atlanta, GA, USA, 3-6 March 2013. Abstract no. 767
-
Lichtenstein K et al. 2013 Statin use is associated with incident diabetes mellitus among patients in the HIV outpatient study. In 20th CROI, Atlanta, GA, USA, 3-6 March 2013. Abstract no. 767.
-
(2013)
20th CROI
-
-
Lichtenstein, K.1
-
231
-
-
84897416431
-
In vivo administration of a JAK3 inhibitor during acute SIV infection leads to significant increases in viral load during chronic infection
-
(doi:10.1371/ journal.ppat.1003929)
-
Takahashi Y et al. 2014 In vivo administration of a JAK3 inhibitor during acute SIV infection leads to significant increases in viral load during chronic infection. PLoS Pathog. 10, e1003929. (doi:10.1371/ journal.ppat.1003929)
-
(2014)
PLoS Pathog.
, vol.10
-
-
Takahashi, Y.1
-
232
-
-
57049085258
-
Early evolution of plasma soluble TNF-alpha p75 receptor as a marker of progression in treated HIVinfected patients
-
(doi:10.1089/aid.2007.0293)
-
Morlat P, Pereira E, Clayette P, Derreudre-Bosquet N, Ecobichon JL, Benveniste O, Saves M, Leport C. 2008 Early evolution of plasma soluble TNF-alpha p75 receptor as a marker of progression in treated HIVinfected patients. AIDS Res. Hum. Retroviruses 24, 1383-1389. (doi:10.1089/aid.2007.0293)
-
(2008)
AIDS Res. Hum. Retroviruses
, vol.24
, pp. 1383-1389
-
-
Morlat, P.1
Pereira, E.2
Clayette, P.3
Derreudre-Bosquet, N.4
Ecobichon, J.L.5
Benveniste, O.6
Saves, M.7
Leport, C.8
-
233
-
-
84859250847
-
Impact of multitargeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection
-
(doi:10.1371/ journal.pone.0033948)
-
Ananworanich J et al. 2012 Impact of multitargeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. PLoS ONE 7, e33948. (doi:10.1371/ journal.pone.0033948)
-
(2012)
PLoS ONE
, vol.7
-
-
Ananworanich, J.1
-
234
-
-
79955918570
-
Cross-sectional detection of acute HIV infection: Timing of transmission, inflammation and antiretroviral therapy
-
(doi:10.1371/journal.pone.0019617)
-
Gay C et al. 2011 Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy. PLoS ONE 6, e19617. (doi:10.1371/journal.pone.0019617)
-
(2011)
PLoS ONE
, vol.6
-
-
Gay, C.1
-
235
-
-
79954988179
-
Single and multiple dose pharmacokinetics of maraviroc in saliva, semen, and rectal tissue of healthy HIV-negative men
-
(doi:10.1093/infdis/jir059)
-
Brown KC et al. 2011 Single and multiple dose pharmacokinetics of maraviroc in saliva, semen, and rectal tissue of healthy HIV-negative men. J. Infect. Dis. 203, 1484-1490. (doi:10.1093/infdis/jir059)
-
(2011)
J. Infect. Dis.
, vol.203
, pp. 1484-1490
-
-
Brown, K.C.1
-
236
-
-
84894046809
-
Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection
-
(doi:10.1097/ QAD.0000000000000066)
-
Puertas MC et al. 2013 Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection. AIDS 28, 325-334. (doi:10.1097/ QAD.0000000000000066)
-
(2013)
AIDS
, vol.28
, pp. 325-334
-
-
Puertas, M.C.1
-
237
-
-
84887375924
-
Response: Maraviroc intensification and microbial translocation
-
(doi:10.1182/blood-2013-08-516930)
-
Hunt PW, Lederman MM, Deeks SG. 2013 Response: maraviroc intensification and microbial translocation. Blood 122, 2283-2284. (doi:10.1182/blood-2013-08-516930)
-
(2013)
Blood
, vol.122
, pp. 2283-2284
-
-
Hunt, P.W.1
Lederman, M.M.2
Deeks, S.G.3
-
238
-
-
84887375643
-
Maraviroc-induced decrease in circulating bacterial products is not linked to an increase in immune activation in HIV-infected individuals
-
(doi:10.1182/ blood-2013-06-507012)
-
Psomas C et al. 2013 Maraviroc-induced decrease in circulating bacterial products is not linked to an increase in immune activation in HIV-infected individuals. Blood 122, 2282-2283. (doi:10.1182/ blood-2013-06-507012)
-
(2013)
Blood
, vol.122
, pp. 2282-2283
-
-
Psomas, C.1
-
239
-
-
84887290531
-
Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers
-
(doi:10.1371/ journal.ppat.1003691)
-
Hatano H et al. 2013 Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. PLoS Pathog. 9, e1003691. (doi:10.1371/ journal.ppat.1003691)
-
(2013)
PLoS Pathog.
, vol.9
-
-
Hatano, H.1
-
240
-
-
84872037286
-
A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication
-
(doi:10.1126/scitranslmed.3004682)
-
Garcia F et al. 2013 A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication. Sci. Transl. Med. 5, 166ra162. (doi:10.1126/scitranslmed.3004682)
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Garcia, F.1
-
241
-
-
84855931820
-
Dendritic cell-targeted protein vaccines: A novel approach to induce T-cell immunity
-
(doi:10.1111/j.1365-2796. 2011.02496.x)
-
Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ, Steinman RM. 2012 Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity. J. Intern. Med. 271, 183-192. (doi:10.1111/j.1365-2796. 2011.02496.x)
-
(2012)
J. Intern. Med.
, vol.271
, pp. 183-192
-
-
Trumpfheller, C.1
Longhi, M.P.2
Caskey, M.3
Idoyaga, J.4
Bozzacco, L.5
Keler, T.6
Schlesinger, S.J.7
Steinman, R.M.8
-
242
-
-
84878552360
-
+ T cells in mice
-
(doi:10.1172/JCI64704)
-
+ T cells in mice. J. Clin. Invest. 123, 2629-2642. (doi:10.1172/JCI64704)
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 2629-2642
-
-
Zhou, J.1
-
243
-
-
79957618772
-
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
-
(doi:10.1038/nature10003)
-
Hansen SG et al. 2011 Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine. Nature 473, 523-527. (doi:10.1038/nature10003)
-
(2011)
Nature
, vol.473
, pp. 523-527
-
-
Hansen, S.G.1
-
244
-
-
84877957880
-
+ T cell epitope recognition paradigms
-
(doi:10.1126/science.1237874)
-
+ T cell epitope recognition paradigms. Science 340, 1237874. (doi:10.1126/science.1237874)
-
(2013)
Science
, vol.340
, pp. 1237874
-
-
Hansen, S.G.1
-
245
-
-
20944446452
-
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
-
(doi:10.1038/nm1244)
-
Trkola A et al. 2005 Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat. Med. 11, 615-622. (doi:10.1038/nm1244)
-
(2005)
Nat. Med.
, vol.11
, pp. 615-622
-
-
Trkola, A.1
-
246
-
-
84869155712
-
Evolution of an HIV glycandependent broadly neutralizing antibody epitope through immune escape
-
(doi:10.1038/nm.2985)
-
Moore PL et al. 2012 Evolution of an HIV glycandependent broadly neutralizing antibody epitope through immune escape. Nat. Med. 18, 1688-1692. (doi:10.1038/nm.2985)
-
(2012)
Nat. Med.
, vol.18
, pp. 1688-1692
-
-
Moore, P.L.1
-
247
-
-
84866495323
-
Human antibodies that neutralize HIV-1: Identification, structures, and B cell ontogenies
-
(doi:10. 1016/j.immuni.2012.08.012)
-
Kwong PD, Mascola JR. 2012 Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies. Immunity 37, 412-425. (doi:10. 1016/j.immuni.2012.08.012)
-
(2012)
Immunity
, vol.37
, pp. 412-425
-
-
Kwong, P.D.1
Mascola, J.R.2
-
248
-
-
84876797103
-
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
-
(doi:10.1038/nature 12053)
-
Liao HX et al. 2013 Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature 496, 469-476. (doi:10.1038/nature 12053)
-
(2013)
Nature
, vol.496
, pp. 469-476
-
-
Liao, H.X.1
-
249
-
-
84877609579
-
Rational HIV immunogen design to target specific germline B cell receptors
-
(doi:10.1126/science.1234150)
-
Jardine J et al. 2013 Rational HIV immunogen design to target specific germline B cell receptors. Science 340, 711-716. (doi:10.1126/science.1234150)
-
(2013)
Science
, vol.340
, pp. 711-716
-
-
Jardine, J.1
-
250
-
-
84878626061
-
Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
-
(doi:10. 1084/jem.20122824)
-
McGuire AT et al. 2013 Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies. J. Exp. Med. 210, 655-663. (doi:10. 1084/jem.20122824)
-
(2013)
J. Exp. Med.
, vol.210
, pp. 655-663
-
-
McGuire, A.T.1
-
251
-
-
84886778874
-
Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys
-
(doi:10.1016/j.cell.2013.09.061)
-
Barouch DH et al. 2013 Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys. Cell 155, 531-539. (doi:10.1016/j.cell.2013.09.061)
-
(2013)
Cell
, vol.155
, pp. 531-539
-
-
Barouch, D.H.1
|