A nonhuman primate model for the selective elimination of CD8+ lymphocytes using a mouse-human chimeric monoclonal antibody

American Journal of Pathology

Volumn 154, Issue 6, 1999, Pages 1923-1932

  Schmitz, Jörn E ^a,f   Simon, Meredith A ^a   Kuroda, Marcelo J ^a   Lifton, Michelle A ^a   Ollert, Markus W ^b   Vogel, Carl Wilhelm ^b   Racz, Paul ^c   Tenner Racz, Klara ^c   Scallon, Bernard J ^d   Dalesandro, Margaret ^d   Ghrayeb, John ^d   Rieber, E Peter ^e   Sasseville, Vito G ^a   Reimann, Keith A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF HAMBURG   (Germany)

^c BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^d CENTOCOR INC   (United States)

^e DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^f BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC ANTIBODY; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DELAYED HYPERSENSITIVITY; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE FUNCTION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; NONHUMAN; PRIMATE; PRIORITY JOURNAL; RHESUS MONKEY;

EID: 0032986421     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65450-8     Document Type: Article

References (29)

1. Yap KL, Ada GL, McKenzie IFC: Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus. Nature 1978, 273:238-239
2. Riddell SR, Greenberg PD: Principles for adoptive T cell therapy of human viral diseases. Annu Rev Immunol 1995, 13:545-586
3. Fung-Leung W-P, Schilham MW, Rahemtulla A, Kundig TM, Vollenweider M, Potter J, van Ewijk W, Mak TW: CD8 is needed for development of cytotoxic T cells but not helper T cells. Cell 1991, 65:443-449
4. Nesic D, Vukmanovic S: MHC class I is required for peripheral accumulation of CD8+ thymic emigrants. J Immunol 1998, 160:3705-3712
5. Mielke ME, Niedobitek G, Stein H, Hahn H: Acquired resistance to Listeria monocytogenes in mediated by Lyt-2+ T cells independently of the influx of monocytes into granulomatous lesions. J Exp Med 1989, 170:589-594
6. McClure HM: Nonhuman primate models for human disease. Adv Vet Sci Comp Med 1984, 28:267-304
7. Lackner AA: Pathology of simian immunodeficiency virus induced disease. Current Topics in Microbiology and Immunology, Vol. 188, Simian Immunodeficiency Virus. Edited by NL Letvin, RC Desrosiers. Berlin, Springer Verlag, 1994, pp 35-64
8. Castro BA, Walker CM, Eichberg JW, Levy JA: Suppression of human immunodeficiency virus replication by CD8+ cells from infected and uninfected chimpanzees. Cell Immunol 1991, 132:246-255
9. Matano T, Shibata R, Siemon C, Connors M, Lane HC, Martin MA: Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus monkeys. J Virol 1998, 72:164-169
10. Looney J E, Willinger A, Lin G, Rieber EP, Riethmüller G. Ghrayeb J: Expression and characterization of cMT-413, a chimeric anti-CD4 antibody with in vitro immunosuppressive activity. J lmmunother Emphasis Tumor Immunol 1994, 16:36-46
11. Rieber EP: T-cell section report. Edited by Knapp W, Doerken B, Gilks WR, Rieber EP, Schmidt RE, Stein H, von dem Borne AEGKr: Leucocyte Typing IV. Oxford University Press, Oxford, 1989, pp 229-249
12. Miller MD, Yamamato H, Hughes AL, Watkins DI, Letvin NL: Definition of an epitope and MHC class I molecule recognized by Gag-specific cytotoxic T lymphocytes in SIVmac-infected rhesus monkeys. J Immunol 1991, 147:320-329
13. Kuroda MJ, Schmitz JE, Barouch DH, Craiu A, Allen TM, Sette A, Watkins DA, Forman MA, Letvin NL: Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex. J Exp Med 1998, 187:1373-1381
14. Seth A, Ourmanov I, Kuroda MJ, Schmitz JE, Carroll MW, Wyatt LS, Moss B, Forman MA, Hirsch VM, Letvin NL: Recombinant modified vaccinia virus Ankara-simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide teramer. Proc Natl Acad Sci USA 1998, 95:10112-10116
15. Vogel C-W, Muller-Eberhard HJ: Cobra venom factor: improved method for purification and biochemical characterization. J Immunol Meth 1984, 73:203-220
16. Schmitz JE, Lifton MA, Reimann KA, Montefiori DC, Shen L, Racz P, Tenner-Racz K, Ollert MW, Forman MA, Gelman RS, Vogel C-W, Letvin NL: Effect of complement consumption by cobra venom factor on the course of primary infection with simian immunodeficiency virus in rhesus monkeys. AIDS Res Hum Retroviruses 1999, 15:195-202
17. Giclas PC: Complement tests. Manual of Clinical Laboratory Immunology. Fifth ed. Edited by NR Rose, E Conway de Macario, JD Folds, HC Lane, RM Nakamura. Washington, DC, AMS Press, 1997, pp 181-202
18. Sasseville VG, Rottman JB, Du Z, Veazey R, Knight HL, Caunt D, Desrosiers RC, Lackner AA: Characterization of the cutaneous exanthem in macaques infected with a Nef gene variant of SIVmac239. J Invest Dermatol 1998, 110:894-901
19. O'Rourke AM, Mescher MF: The roles of CD8 in cytotoxic T lymphocyte function. Immunol Today 1993, 14:183-188
20. Mackall CL, Fleisher TA, Brown MR, Andrich MP, Chen CC, Feuerstein IM, Horowitz ME, Magrath IT, Shad AT, Steinberg SM, Wexler LH, Gress RE: Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy: N Engl J Med 1995, 332:143-149
21. Neville DM Jr, Scharff J, Hu HZ, Rigaut K, Shiloach J, Slingland W, Jonker M: A new reagent for the induction of T cell depletion, anti-CD3-CRM9. J Immunother Emphasis Tumor Immunol 1996, 19:85-92
22. Vogel C-W: Cobra venom factor: the complement-activating protein of cobra venom. Handbook of Natural Toxins, vol. 5. Edited by AT Tu. New York, Marcel Dekker, 1991, pp 147-188
23. Frew AJ, Kay AB: Eosinophils and T-lymphocytes in late-phase allergic reactions. J Allergy Clin Immunol 1990, 85:533-539
24. Colditz IG, Watson DL: The effect of cytokines and chemotactic agonists on the migrations of T lymphocytes into skin. Immunology 1992, 76:272-278
25. Baldridge JR, Ward JR: Effective adjuvants for the induction of antigen-specific delayed-type hypersensitivity. Vaccine 1997, 15:395-401
26. Blanchi ATJ, Moonen-Leusen HWM, van Milligen FJ, Savelkoul HFJ, Zwart RJ, Kimman TG: A mouse model to study immunity against pseudorabies virus infection: significance of CD4+ and CD8+ cells in protective immunity. Vaccine 1998, 16:1550-1558
27. Rice JC, Bucy RP: Difference in degree of depletion, rate of recovery, and the preferential elimination of naive CD4+ T cells by anti-CD4 monoclonal antibody (GK1.5) in young and aged mice. J Immunol 1995, 154:6644-6654
28. Mackall CL, Gress RE: Thymic aging and T-cell regeneration. Immunol Rev 1997, 160:91-102
29. Wyand MS, Manson KH, Garcia-Moll M, Montefiori D, Desrosiers RC: Vaccine protection by a triple deletion mutant of simian immunodeficiency virus. J Virol 1996, 70:3724-3733