메뉴 건너뛰기




Volumn 21, Issue 4, 2013, Pages 128-132

Immune activation, HIV persistence, and the cure

Author keywords

Gut; HIV; Immune activation; Lymphoid tissue; Microbial translocation; Persistence; Raltegravir intensification; Reservoir

Indexed keywords

ANTICOAGULANT AGENT; ANTIFIBROTIC AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; CENICRIVIROC; FATTY ACID BINDING PROTEIN 2; GROWTH HORMONE; INTERLEUKIN 7; MARAVIROC; RALTEGRAVIR; RIFAXIMIN; SEVELAMER; TUMOR NECROSIS FACTOR INHIBITOR; VITAMIN D; 2 PYRROLIDONE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 84887160135     PISSN: 21615861     EISSN: 21615853     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (26)

References (17)
  • 1
    • 39349088126 scopus 로고    scopus 로고
    • Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy
    • Hunt PW, Brenchley J, Sinclair E, et al. Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J Infect Dis. 2008;197:126-133.
    • (2008) J Infect Dis. , vol.197 , pp. 126-133
    • Hunt, P.W.1    Brenchley, J.2    Sinclair, E.3
  • 2
    • 0038701685 scopus 로고    scopus 로고
    • T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
    • Hunt PW, Martin JN, Sinclair E, et al. T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis. 2003;187(10): 1534-1543.
    • (2003) J Infect Dis. , vol.187 , Issue.10 , pp. 1534-1543
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3
  • 3
    • 84876409512 scopus 로고    scopus 로고
    • Gut epithelial barrier dysfunction, inflammation, and coagulation predict higher mortality during treated HIV/AIDS [Abstract 278]
    • March 5-8 Seattle, Washington
    • Hunt P, Rodriguez B, Shive C, et al. Gut epithelial barrier dysfunction, inflammation, and coagulation predict higher mortality during treated HIV/AIDS [Abstract 278]. 19th Conference on Retroviruses and Opportunistic Infections (CROI). March 5-8, 2012; Seattle, Washington.
    • (2012) 19th Conference on Retroviruses and Opportunistic Infections (CROI)
    • Hunt, P.1    Rodriguez, B.2    Shive, C.3
  • 4
    • 84860345691 scopus 로고    scopus 로고
    • Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: A randomized 48-week study
    • Llibre JM, Buzon MJ, Massanella M, et al. Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study. Antivir Ther. 2012;17(2):355-364.
    • (2012) Antivir Ther. , vol.17 , Issue.2 , pp. 355-364
    • Llibre, J.M.1    Buzon, M.J.2    Massanella, M.3
  • 5
    • 84866707088 scopus 로고    scopus 로고
    • The effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients
    • Vallejo A, Gutierrez C, Hernandez-Novoa B, et al. The effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients. AIDS. 2012;26(15):1885-1894.
    • (2012) AIDS. , vol.26 , Issue.15 , pp. 1885-1894
    • Vallejo, A.1    Gutierrez, C.2    Hernandez-Novoa, B.3
  • 6
    • 77956856393 scopus 로고    scopus 로고
    • The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: A randomized controlled trial
    • Ghandi RT, Zheng L, Bosch RJ, et al. The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS Clin Trials. 2010;7(8):pii:e1000321.
    • (2010) PLoS Clin Trials. , vol.7 , Issue.8
    • Ghandi, R.T.1    Zheng, L.2    Bosch, R.J.3
  • 7
    • 84857362006 scopus 로고    scopus 로고
    • Mucosal correlates of isolated HIV semen shedding during effective antiretroviral therapy
    • Sheth PM, Yi TJ, Kovacs C, et al. Mucosal correlates of isolated HIV semen shedding during effective antiretroviral therapy. Mucosal Immunol. 2012;5(3):248-257.
    • (2012) Mucosal Immunol. , vol.5 , Issue.3 , pp. 248-257
    • Sheth, P.M.1    Yi, T.J.2    Kovacs, C.3
  • 8
    • 78549245806 scopus 로고    scopus 로고
    • Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy
    • Yukl SA, Shergill AK, McQuaid K, et al. Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy. AIDS. 2010;24(16):2451-2460.
    • (2010) AIDS. , vol.24 , Issue.16 , pp. 2451-2460
    • Yukl, S.A.1    Shergill, A.K.2    McQuaid, K.3
  • 9
    • 84875985311 scopus 로고    scopus 로고
    • Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study
    • Saez-Cirion A, Bacchus C, Hocqueloux L, et al. Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog. 2013;9(3):e1003211.
    • (2013) PLoS Pathog. , vol.9 , Issue.3
    • Saez-Cirion, A.1    Bacchus, C.2    Hocqueloux, L.3
  • 10
    • 79953000877 scopus 로고    scopus 로고
    • A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response
    • Hatano H, Hayes TL, Dahl V, et al. A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. J Infect Dis. 2011;203(7):960-968.
    • (2011) J Infect Dis. , vol.203 , Issue.7 , pp. 960-968
    • Hatano, H.1    Hayes, T.L.2    Dahl, V.3
  • 11
    • 60549090253 scopus 로고    scopus 로고
    • Long-term control of HIV by CCR5 Delta32/ Delta32 stem-cell transplantation
    • Hutter G, Nowak D, Mossner M, et al. Long-term control of HIV by CCR5 Delta32/ Delta32 stem-cell transplantation. N Engl J Med. 2009;360(7):692-698.
    • (2009) N Engl J Med. , vol.360 , Issue.7 , pp. 692-698
    • Hutter, G.1    Nowak, D.2    Mossner, M.3
  • 12
    • 0038316325 scopus 로고    scopus 로고
    • Anatomical basis of tolerance and immunity to intestinal antigens
    • Mowat AM. Anatomical basis of tolerance and immunity to intestinal antigens. Nat Rev Immunol. 2003;3(4):331-341.
    • (2003) Nat Rev Immunol. , vol.3 , Issue.4 , pp. 331-341
    • Mowat, A.M.1
  • 13
    • 44649201289 scopus 로고    scopus 로고
    • HIV infection and the gastrointestinal immune system
    • Brenchley JM, Douek DC. HIV infection and the gastrointestinal immune system. Mucosal Immunol. 2008;1(1): 23-30.
    • (2008) Mucosal Immunol. , vol.1 , Issue.1 , pp. 23-30
    • Brenchley, J.M.1    Douek, D.C.2
  • 14
    • 84879318140 scopus 로고    scopus 로고
    • Immune activation and HIV persistence: Implications for curative approaches to HIV infection
    • Klatt NR, Chomont N, Douek DC, Deeks SG. Immune activation and HIV persistence: implications for curative approaches to HIV infection. Immunol Rev. 2013;254(1):326-342.
    • (2013) Immunol Rev. , vol.254 , Issue.1 , pp. 326-342
    • Klatt, N.R.1    Chomont, N.2    Douek, D.C.3    Deeks, S.G.4
  • 15
    • 84862236428 scopus 로고    scopus 로고
    • HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activation
    • Armah KA, McGinnis K, Baker J, et al. HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activation. Clin Infect Dis. 2012;55(1):126-136.
    • (2012) Clin Infect Dis. , vol.55 , Issue.1 , pp. 126-136
    • Armah, K.A.1    McGinnis, K.2    Baker, J.3
  • 16
    • 84864345953 scopus 로고    scopus 로고
    • Towards an HIV cure: A global scientific strategy
    • Deeks SG, Autran B, Berkhout B, et al. Towards an HIV cure: a global scientific strategy. Nat Rev Immunol. 2012;12(8):607-614.
    • (2012) Nat Rev Immunol. , vol.12 , Issue.8 , pp. 607-614
    • Deeks, S.G.1    Autran, B.2    Berkhout, B.3
  • 17
    • 84865163472 scopus 로고    scopus 로고
    • Microbial translocation in HIV infection: Causes, consequences and treatment opportunities
    • Sandler NG, Douek DC. Microbial translocation in HIV infection: causes, consequences and treatment opportunities. Nat Rev Microbiol. 2012;10(9):655-666.
    • (2012) Nat Rev Microbiol. , vol.10 , Issue.9 , pp. 655-666
    • Sandler, N.G.1    Douek, D.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.