메뉴 건너뛰기




Volumn 9, Issue 5, 2013, Pages

Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

(28)  Yukl, Steven A a   Boritz, Eli b   Busch, Michael c   Bentsen, Christopher d   Chun, Tae Wook e   Douek, Daniel b   Eisele, Evelyn f   Haase, Ashley g   Ho, Ya Chi f   Hütter, Gero h   Justement, J Shawn e   Keating, Sheila c   Lee, Tzong Hae c   Li, Peilin a   Murray, Danielle e   Palmer, Sarah i   Pilcher, Christopher j   Pillai, Satish a   Price, Richard W a   Rothenberger, Meghan g   more..


Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD20 ANTIGEN; CHEMOKINE RECEPTOR CCR5; GLYCOPROTEIN P 15095; TRANSCRIPTOME;

EID: 84878503062     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003347     Document Type: Article
Times cited : (226)

References (56)
  • 4
    • 79953117041 scopus 로고    scopus 로고
    • Evidence for the cure of HIV infection by CCR5Delta32/Delta32 stem cell transplantation
    • Allers K, Hutter G, Hofmann J, Loddenkemper C, Rieger K, et al. (2011) Evidence for the cure of HIV infection by CCR5Delta32/Delta32 stem cell transplantation. Blood 117: 2791-2799.
    • (2011) Blood , vol.117 , pp. 2791-2799
    • Allers, K.1    Hutter, G.2    Hofmann, J.3    Loddenkemper, C.4    Rieger, K.5
  • 5
    • 84923315310 scopus 로고    scopus 로고
    • The cure of the 'Berlin patient': why did pre-existing X4-variants not emergence after allogeneic CCR5-Δ32 SCT?
    • Washington, D.C
    • Symons J, Deeks S, Hutter G, Wensing A, Martin J, et al. (2012) The cure of the 'Berlin patient': why did pre-existing X4-variants not emergence after allogeneic CCR5-Δ32 SCT?. 19th International AIDS Conference. Washington, D.C.
    • (2012) 19th International AIDS Conference
    • Symons, J.1    Deeks, S.2    Hutter, G.3    Wensing, A.4    Martin, J.5
  • 6
    • 53849134844 scopus 로고    scopus 로고
    • Cellular reservoirs of HIV-1 and their role in viral persistence
    • Alexaki A, Liu Y, Wigdahl B, (2008) Cellular reservoirs of HIV-1 and their role in viral persistence. Current HIV research 6: 388-400.
    • (2008) Current HIV Research , vol.6 , pp. 388-400
    • Alexaki, A.1    Liu, Y.2    Wigdahl, B.3
  • 8
    • 0030913366 scopus 로고    scopus 로고
    • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • Chun TW, Carruth L, Finzi D, Shen X, DiGiuseppe JA, et al. (1997) Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387: 183-188.
    • (1997) Nature , vol.387 , pp. 183-188
    • Chun, T.W.1    Carruth, L.2    Finzi, D.3    Shen, X.4    DiGiuseppe, J.A.5
  • 9
    • 14444273439 scopus 로고    scopus 로고
    • Identification of a reservoir for HIV in patients on highly active antiretroviral therapy
    • Finzi D, Hermankova M, Pierson T, Carruth L, Buck C, et al. (1997) Identification of a reservoir for HIV in patients on highly active antiretroviral therapy. Science 278: 1295-1300.
    • (1997) Science , vol.278 , pp. 1295-1300
    • Finzi, D.1    Hermankova, M.2    Pierson, T.3    Carruth, L.4    Buck, C.5
  • 10
    • 0030712305 scopus 로고    scopus 로고
    • Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
    • Wong JK, Hezareh M, Gunthard HF, Havlir DV, Ignacio CC, et al. (1997) Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 278: 1291-1295.
    • (1997) Science , vol.278 , pp. 1291-1295
    • Wong, J.K.1    Hezareh, M.2    Gunthard, H.F.3    Havlir, D.V.4    Ignacio, C.C.5
  • 11
    • 0032953920 scopus 로고    scopus 로고
    • Latent infection of CD4 Tcells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
    • Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, et al. (1999) Latent infection of CD4 Tcells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nature Medicine 5: 512-517.
    • (1999) Nature Medicine , vol.5 , pp. 512-517
    • Finzi, D.1    Blankson, J.2    Siliciano, J.D.3    Margolick, J.B.4    Chadwick, K.5
  • 12
    • 0038579210 scopus 로고    scopus 로고
    • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
    • Siliciano JD, Kajdas J, Finzi D, Quinn TC, Chadwick K, et al. (2003) Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med 9: 727-728.
    • (2003) Nat Med , vol.9 , pp. 727-728
    • Siliciano, J.D.1    Kajdas, J.2    Finzi, D.3    Quinn, T.C.4    Chadwick, K.5
  • 13
    • 10544241554 scopus 로고    scopus 로고
    • Quantitative image analysis of HIV-1 infection in lymphoid tissue
    • Haase AT, Henry K, Zupancic M, Sedgewick G, Faust RA, et al. (1996) Quantitative image analysis of HIV-1 infection in lymphoid tissue. Science 274: 985-989.
    • (1996) Science , vol.274 , pp. 985-989
    • Haase, A.T.1    Henry, K.2    Zupancic, M.3    Sedgewick, G.4    Faust, R.A.5
  • 14
    • 0030730288 scopus 로고    scopus 로고
    • Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure
    • Wong JK, Gunthard HF, Havlir DV, Zhang ZQ, Haase AT, et al. (1997) Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure. Proc Natl Acad Sci U S A 94: 12574-12579.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 12574-12579
    • Wong, J.K.1    Gunthard, H.F.2    Havlir, D.V.3    Zhang, Z.Q.4    Haase, A.T.5
  • 15
    • 0033869954 scopus 로고    scopus 로고
    • Treatment-induced decline of human immunodeficiency virus-1 p24 and HIV-1 RNA in lymphoid tissue of patients with early human immunodeficiency virus-1 infection
    • Kuster H, Opravil M, Ott P, Schlaepfer E, Fischer M, et al. (2000) Treatment-induced decline of human immunodeficiency virus-1 p24 and HIV-1 RNA in lymphoid tissue of patients with early human immunodeficiency virus-1 infection. Am J Pathol 156: 1973-1986.
    • (2000) Am J Pathol , vol.156 , pp. 1973-1986
    • Kuster, H.1    Opravil, M.2    Ott, P.3    Schlaepfer, E.4    Fischer, M.5
  • 16
    • 33748110086 scopus 로고    scopus 로고
    • Lack of decay of HIV-1 in gut-associated lymphoid tissue reservoirs in maximally suppressed individuals
    • Poles MA, Boscardin WJ, Elliott J, Taing P, Fuerst MM, et al. (2006) Lack of decay of HIV-1 in gut-associated lymphoid tissue reservoirs in maximally suppressed individuals. J Acquir Immune Defic Syndr 43: 65-68.
    • (2006) J Acquir Immune Defic Syndr , vol.43 , pp. 65-68
    • Poles, M.A.1    Boscardin, W.J.2    Elliott, J.3    Taing, P.4    Fuerst, M.M.5
  • 18
    • 78149417719 scopus 로고    scopus 로고
    • Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy
    • Yukl SA, Gianella S, Sinclair E, Epling L, Li Q, et al. Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy. J Infect Dis 202: 1553-1561.
    • J Infect Dis , vol.202 , pp. 1553-1561
    • Yukl, S.A.1    Gianella, S.2    Sinclair, E.3    Epling, L.4    Li, Q.5
  • 19
    • 79957966626 scopus 로고    scopus 로고
    • Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy
    • Chun TW, Murray D, Justement JS, Hallahan CW, Moir S, et al. (2011) Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy. The Journal of infectious diseases 204: 135-138.
    • (2011) The Journal of Infectious Diseases , vol.204 , pp. 135-138
    • Chun, T.W.1    Murray, D.2    Justement, J.S.3    Hallahan, C.W.4    Moir, S.5
  • 20
    • 10744228049 scopus 로고    scopus 로고
    • New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma
    • Palmer S, Wiegand AP, Maldarelli F, Bazmi H, Mican JM, et al. (2003) New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol 41: 4531-4536.
    • (2003) J Clin Microbiol , vol.41 , pp. 4531-4536
    • Palmer, S.1    Wiegand, A.P.2    Maldarelli, F.3    Bazmi, H.4    Mican, J.M.5
  • 21
    • 33644790467 scopus 로고    scopus 로고
    • Relative sensitivities of licensed nucleic acid amplification tests for detection of viremia in early human immunodeficiency virus and hepatitis C virus infection
    • Busch MP, Glynn SA, Wright DJ, Hirschkorn D, Laycock ME, et al. (2005) Relative sensitivities of licensed nucleic acid amplification tests for detection of viremia in early human immunodeficiency virus and hepatitis C virus infection. Transfusion 45: 1853-1863.
    • (2005) Transfusion , vol.45 , pp. 1853-1863
    • Busch, M.P.1    Glynn, S.A.2    Wright, D.J.3    Hirschkorn, D.4    Laycock, M.E.5
  • 22
    • 58149382617 scopus 로고    scopus 로고
    • Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy
    • Hatano H, Delwart EL, Norris PJ, Lee TH, Dunn-Williams J, et al. (2009) Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy. J Virol 83: 329-335.
    • (2009) J Virol , vol.83 , pp. 329-335
    • Hatano, H.1    Delwart, E.L.2    Norris, P.J.3    Lee, T.H.4    Dunn-Williams, J.5
  • 23
    • 79959329392 scopus 로고    scopus 로고
    • Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliter
    • Yukl SA, Li P, Fujimoto K, Lampiris H, Lu CM, et al. (2011) Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliter. Journal of virological methods 175: 261-265.
    • (2011) Journal of Virological Methods , vol.175 , pp. 261-265
    • Yukl, S.A.1    Li, P.2    Fujimoto, K.3    Lampiris, H.4    Lu, C.M.5
  • 25
    • 84863242863 scopus 로고    scopus 로고
    • HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy
    • Durand CM, Ghiaur G, Siliciano JD, Rabi SA, Eisele EE, et al. (2012) HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy. The Journal of infectious diseases 205: 1014-1018.
    • (2012) The Journal of Infectious Diseases , vol.205 , pp. 1014-1018
    • Durand, C.M.1    Ghiaur, G.2    Siliciano, J.D.3    Rabi, S.A.4    Eisele, E.E.5
  • 27
    • 0030659177 scopus 로고    scopus 로고
    • Presence of an inducible HIV latent reservoir during highly active antiretroviral therapy
    • Chun TW, Stuyver L, Mizell SB, Ehler LA, Mican JM, et al. (1997) Presence of an inducible HIV latent reservoir during highly active antiretroviral therapy. PNAS 94: 13193-13197.
    • (1997) PNAS , vol.94 , pp. 13193-13197
    • Chun, T.W.1    Stuyver, L.2    Mizell, S.B.3    Ehler, L.A.4    Mican, J.M.5
  • 28
    • 24944518559 scopus 로고    scopus 로고
    • Enhanced culture assay for detection and quantitation of latently infected, resting CD4+ T-cells carrying replication-competent virus in HIV-1-infected individuals
    • Siliciano JD, Siliciano RF, (2005) Enhanced culture assay for detection and quantitation of latently infected, resting CD4+ T-cells carrying replication-competent virus in HIV-1-infected individuals. Methods in molecular biology 304: 3-15.
    • (2005) Methods in Molecular Biology , vol.304 , pp. 3-15
    • Siliciano, J.D.1    Siliciano, R.F.2
  • 29
    • 84869224218 scopus 로고    scopus 로고
    • Lower-sensitivity and avidity modifications of the vitros anti-HIV 1+2 assay for detection of recent HIV infections and incidence estimation
    • Keating SM, Hanson D, Lebedeva M, Laeyendecker O, Ali-Napo NL, et al. (2012) Lower-sensitivity and avidity modifications of the vitros anti-HIV 1+2 assay for detection of recent HIV infections and incidence estimation. Journal of clinical microbiology 50: 3968-3976.
    • (2012) Journal of Clinical Microbiology , vol.50 , pp. 3968-3976
    • Keating, S.M.1    Hanson, D.2    Lebedeva, M.3    Laeyendecker, O.4    Ali-Napo, N.L.5
  • 30
    • 84858994632 scopus 로고    scopus 로고
    • Detection of recent HIV-1 infection using a new limiting-antigen avidity assay: potential for HIV-1 incidence estimates and avidity maturation studies
    • Duong YT, Qiu M, De AK, Jackson K, Dobbs T, et al. (2012) Detection of recent HIV-1 infection using a new limiting-antigen avidity assay: potential for HIV-1 incidence estimates and avidity maturation studies. PLoS ONE 7: e33328.
    • (2012) PLoS ONE , vol.7
    • Duong, Y.T.1    Qiu, M.2    De, A.K.3    Jackson, K.4    Dobbs, T.5
  • 31
    • 77957571862 scopus 로고    scopus 로고
    • IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery
    • Ndhlovu LC, Sinclair E, Epling L, Tan QX, Ho T, et al. (2010) IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery. Journal of clinical immunology 30: 681-692.
    • (2010) Journal of Clinical Immunology , vol.30 , pp. 681-692
    • Ndhlovu, L.C.1    Sinclair, E.2    Epling, L.3    Tan, Q.X.4    Ho, T.5
  • 32
    • 59349092367 scopus 로고    scopus 로고
    • Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapy
    • Fischer M, Joos B, Niederost B, Kaiser P, Hafner R, et al. (2008) Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapy. Retrovirology 5: 107.
    • (2008) Retrovirology , vol.5 , pp. 107
    • Fischer, M.1    Joos, B.2    Niederost, B.3    Kaiser, P.4    Hafner, R.5
  • 33
    • 0025815375 scopus 로고
    • Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes
    • Li Y, Kappes JC, Conway JA, Price RW, Shaw GM, et al. (1991) Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and-defective viral genomes. J Virol 65: 3973-3985.
    • (1991) J Virol , vol.65 , pp. 3973-3985
    • Li, Y.1    Kappes, J.C.2    Conway, J.A.3    Price, R.W.4    Shaw, G.M.5
  • 34
    • 0031048979 scopus 로고    scopus 로고
    • Accumulation of defective viral genomes in peripheral blood mononuclear cells fo HIV infected individuals
    • Sanchez G, Xu X, Chermann JC, Hirsch I, (1997) Accumulation of defective viral genomes in peripheral blood mononuclear cells fo HIV infected individuals. Journal of Virology 71: 2233-2240.
    • (1997) Journal of Virology , vol.71 , pp. 2233-2240
    • Sanchez, G.1    Xu, X.2    Chermann, J.C.3    Hirsch, I.4
  • 35
    • 0027410369 scopus 로고
    • High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR
    • Piatak M Jr, Saag MS, Yang LC, Clark SJ, Kappes JC, et al. (1993) High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR. Science 259: 1749-1754.
    • (1993) Science , vol.259 , pp. 1749-1754
    • Piatak Jr., M.1    Saag, M.S.2    Yang, L.C.3    Clark, S.J.4    Kappes, J.C.5
  • 36
    • 84873472629 scopus 로고    scopus 로고
    • Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
    • Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, et al. (2013) Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies. PLoS pathogens 9: e1003174.
    • (2013) PLoS Pathogens , vol.9
    • Eriksson, S.1    Graf, E.H.2    Dahl, V.3    Strain, M.C.4    Yukl, S.A.5
  • 37
    • 17544371675 scopus 로고    scopus 로고
    • Early therapy of vertical human immunodeficiency virus type 1 (HIV-1) infection: control of viral replication and absence of persistent HIV-1-specific immune responses
    • Luzuriaga K, McManus M, Catalina M, Mayack S, Sharkey M, et al. (2000) Early therapy of vertical human immunodeficiency virus type 1 (HIV-1) infection: control of viral replication and absence of persistent HIV-1-specific immune responses. Journal of virology 74: 6984-6991.
    • (2000) Journal of Virology , vol.74 , pp. 6984-6991
    • Luzuriaga, K.1    McManus, M.2    Catalina, M.3    Mayack, S.4    Sharkey, M.5
  • 38
    • 0033823590 scopus 로고    scopus 로고
    • The effect of highly active antiretroviral therapy on binding and neutralizing antibody responses to human immunodeficiency virus type 1 infection
    • Binley JM, Trkola A, Ketas T, Schiller D, Clas B, et al. (2000) The effect of highly active antiretroviral therapy on binding and neutralizing antibody responses to human immunodeficiency virus type 1 infection. The Journal of infectious diseases 182: 945-949.
    • (2000) The Journal of Infectious Diseases , vol.182 , pp. 945-949
    • Binley, J.M.1    Trkola, A.2    Ketas, T.3    Schiller, D.4    Clas, B.5
  • 39
    • 33144484395 scopus 로고    scopus 로고
    • Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection
    • Hare CB, Pappalardo BL, Busch MP, Karlsson AC, Phelps BH, et al. (2006) Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection. Clin Infect Dis 42: 700-708.
    • (2006) Clin Infect Dis , vol.42 , pp. 700-708
    • Hare, C.B.1    Pappalardo, B.L.2    Busch, M.P.3    Karlsson, A.C.4    Phelps, B.H.5
  • 41
    • 69549116580 scopus 로고    scopus 로고
    • Genetic and antigenic features of the transmitted virus
    • Keele BF, Derdeyn CA, (2009) Genetic and antigenic features of the transmitted virus. Current opinion in HIV and AIDS 4: 352-357.
    • (2009) Current Opinion in HIV and AIDS , vol.4 , pp. 352-357
    • Keele, B.F.1    Derdeyn, C.A.2
  • 42
    • 66049139947 scopus 로고    scopus 로고
    • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
    • Salazar-Gonzalez JF, Salazar MG, Keele BF, Learn GH, Giorgi EE, et al. (2009) Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. The Journal of experimental medicine 206: 1273-1289.
    • (2009) The Journal of Experimental Medicine , vol.206 , pp. 1273-1289
    • Salazar-Gonzalez, J.F.1    Salazar, M.G.2    Keele, B.F.3    Learn, G.H.4    Giorgi, E.E.5
  • 43
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
    • Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, et al. (1996) Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 273: 1856-1862.
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1    Carrington, M.2    Winkler, C.3    Huttley, G.A.4    Smith, M.W.5
  • 44
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
    • Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, et al. (1996) Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86: 367-377.
    • (1996) Cell , vol.86 , pp. 367-377
    • Liu, R.1    Paxton, W.A.2    Choe, S.3    Ceradini, D.4    Martin, S.R.5
  • 45
    • 16044373004 scopus 로고    scopus 로고
    • Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
    • Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C, et al. (1996) Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382: 722-725.
    • (1996) Nature , vol.382 , pp. 722-725
    • Samson, M.1    Libert, F.2    Doranz, B.J.3    Rucker, J.4    Liesnard, C.5
  • 46
    • 0031051739 scopus 로고    scopus 로고
    • HIV-1 infection in an individual homozygous for the CCR5 deletion allele
    • Biti R, Ffrench R, Young J, Bennetts B, Stewart G, et al. (1997) HIV-1 infection in an individual homozygous for the CCR5 deletion allele. Nature medicine 3: 252-253.
    • (1997) Nature Medicine , vol.3 , pp. 252-253
    • Biti, R.1    Ffrench, R.2    Young, J.3    Bennetts, B.4    Stewart, G.5
  • 47
    • 0030976601 scopus 로고    scopus 로고
    • HIV-1 infection in an individual homozygous for CCR5 delta 32. Seroco Study Group
    • Theodorou I, Meyer L, Magierowska M, Katlama C, Rouzioux C, (1997) HIV-1 infection in an individual homozygous for CCR5 delta 32. Seroco Study Group. Lancet 349: 1219-1220.
    • (1997) Lancet , vol.349 , pp. 1219-1220
    • Theodorou, I.1    Meyer, L.2    Magierowska, M.3    Katlama, C.4    Rouzioux, C.5
  • 49
    • 84875233718 scopus 로고    scopus 로고
    • HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Delta32/Delta32
    • Ballana E, Riveira-Munoz E, Pou C, Bach V, Parera M, et al. (2012) HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Delta32/Delta32. Immunobiology 218: 543-7.
    • (2012) Immunobiology , vol.218 , pp. 543-547
    • Ballana, E.1    Riveira-Munoz, E.2    Pou, C.3    Bach, V.4    Parera, M.5
  • 51
    • 34247262093 scopus 로고    scopus 로고
    • Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote
    • Gorry PR, Dunfee RL, Mefford ME, Kunstman K, Morgan T, et al. (2007) Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology 362: 163-178.
    • (2007) Virology , vol.362 , pp. 163-178
    • Gorry, P.R.1    Dunfee, R.L.2    Mefford, M.E.3    Kunstman, K.4    Morgan, T.5
  • 52
    • 0028244846 scopus 로고
    • Follicular dendritic cells retain HIV-1 particles on their plasma membrane, but are not productively infected in asymptomatic patients with follicular hyperplasia
    • Schmitz J, van Lunzen J, Tenner-Racz K, Grossschupff G, Racz P, et al. (1994) Follicular dendritic cells retain HIV-1 particles on their plasma membrane, but are not productively infected in asymptomatic patients with follicular hyperplasia. Journal of immunology 153: 1352-1359.
    • (1994) Journal of Immunology , vol.153 , pp. 1352-1359
    • Schmitz, J.1    van Lunzen, J.2    Tenner-Racz, K.3    Grossschupff, G.4    Racz, P.5
  • 54
    • 15144342918 scopus 로고    scopus 로고
    • Kinetics of Response in lymphoid tissues to antiretroviral therapy of HIV-1 infection
    • Cavert W, Notermans DW, Staskus K, Wietgrefe S, Zupancic M, et al. (1997) Kinetics of Response in lymphoid tissues to antiretroviral therapy of HIV-1 infection. Science 276: 960-964.
    • (1997) Science , vol.276 , pp. 960-964
    • Cavert, W.1    Notermans, D.W.2    Staskus, K.3    Wietgrefe, S.4    Zupancic, M.5
  • 55
    • 84861203962 scopus 로고    scopus 로고
    • Comprehensive analysis of unique cases with extraordinary control over HIV replication
    • Mendoza D, Johnson SA, Peterson BA, Natarajan V, Salgado M, et al. (2012) Comprehensive analysis of unique cases with extraordinary control over HIV replication. Blood 119: 4645-4655.
    • (2012) Blood , vol.119 , pp. 4645-4655
    • Mendoza, D.1    Johnson, S.A.2    Peterson, B.A.3    Natarajan, V.4    Salgado, M.5
  • 56
    • 34447338029 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 RNA Levels in different regions of human brain: quantification using real-time reverse transcriptase-polymerase chain reaction
    • Kumar AM, Borodowsky I, Fernandez B, Gonzalez L, Kumar M, (2007) Human immunodeficiency virus type 1 RNA Levels in different regions of human brain: quantification using real-time reverse transcriptase-polymerase chain reaction. J Neurovirol 13: 210-224.
    • (2007) J Neurovirol , vol.13 , pp. 210-224
    • Kumar, A.M.1    Borodowsky, I.2    Fernandez, B.3    Gonzalez, L.4    Kumar, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.