HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection

Journal of Virology

Volumn 83, Issue 13, 2009, Pages 6798-6805

  Alter, Galit ^c,d   Rihn, Suzannah ^c,d   Walter, Katharine ^c,d   Nolting, Anne ^c,d   Martin, Maureen ^a   Rosenberg, Eric S ^c,d   Miller, Jeffrey S ^b   Carrington, Mary ^a   Altfeld, Marcus ^c,d  

^a SAIC FREDERICK INC   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 1; HLA B ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS1; MESSENGER RNA;

ARTICLE; CELL EXPANSION; CELL FUNCTION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INFECTION CONTROL; INNATE IMMUNITY; MAJOR CLINICAL STUDY; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS REPLICATION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; METABOLISM; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

HIV INFECTIONS; HIV-1; HLA-B ANTIGENS; HUMANS; KILLER CELLS, NATURAL; RECEPTORS, KIR3DL1; RECEPTORS, KIR3DS1; RNA, MESSENGER;

EID: 67449101826     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00256-09     Document Type: Article

References (37)

1. Alter, G., M. P. Martin, N. Teigen, W. H. Carr, T. J. Suscovich, A. Schneidewind, H. Streeck, M. Waring, A. Meier, C. Brander, J. D. Lifson, T. M. Allen, M. Carrington, and M. Altfeld. 2007. Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. J. Exp. Med. 204:3027-3036.
2. Alter, G., N. Teigen, R. Ahern, H. Streeck, A. Meier, E. S. Rosenberg, and M. Altfeld. 2007. Evolution of innate and adaptive effector cell functions during acute HIV-1 infection. J. Infect. Dis. 195:1452-1460.
3. Alter, G., N. Teigen, B. T. Davis, M. M. Addo, T. J. Suscovich, M. T. Waring, H. Streeck, M. N. Johnston, K. D. Staller, M. T. Zaman, X. G. Yu, M. Lichterfeld, N. Basgoz, E. S. Rosenberg, and M. Altfeld. 2005. Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection. Blood 106:3366-3369. (Pubitemid 41609166)
4. Altfeld, M., and P. Goulder. 2007. 'Unleashed' natural killers hinder HIV. Nat. Genet. 39:708-710.
5. Andrews, D. M., A. A. Scalzo, W. M. Yokoyama, M. J. Smyth, and M. A. Degli-Esposti. 2003. Functional interactions between dendritic cells and NK cells during viral infection. Nat. Immunol. 4:175-181.
6. Anfossi, N., P. Andre, S. Guia, C. S. Falk, S. Roetynck, C. A. Stewart, V. Breso, C. Frassati, D. Reviron, D. Middleton, F. Romagne, S. Ugolini, and E. Vivier. 2006. Human NK cell education by inhibitory receptors for MHC class I. Immunity 25:331-342. (Pubitemid 44224147)
7. Bashirova, A. A., M. P. Martin, D. W. McVicar, and M. Carrington. 2006. The killer immunoglobulin-like receptor gene cluster: tuning the genome for defense. Annu. Rev. Genomics Hum. Genet. 7:277-300.
8. Biassoni, R., C. Cantoni, D. Pende, S. Sivori, S. Parolini, M. Vitale, C. Bottino, and A. Moretta. 2001. Human natural killer cell receptors and co-receptors. Immunol. Rev. 181:203-214.
9. Biron, C. A. 1999. Initial and innate responses to viral infections - pattern setting in immunity or disease. Curr. Opin. Microbiol. 2:374-381.
10. Carr, W. H., D. B. Rosen, H. Arase, D. F. Nixon, J. Michaelsson, and L. L. Lanier. 2007. Cutting edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation. J. Immunol. 178:647-651. (Pubitemid 46095135)
11. Carrington, M., S. Wang, M. P. Martin, X. Gao, M. Schiffman, J. Cheng, R. Herrero, A. C. Rodriguez, R. Kurman, R. Mortel, P. Schwartz, A. Glass, and A. Hildesheim. 2005. Hierarchy of resistance to cervical neoplasia mediated by combinations of killer immunoglobulin-like receptor and human leukocyte antigen loci. J. Exp. Med. 201:1069-1075.
12. Cerwenka, A., and L. L. Lanier. 2001. Natural killer cells, viruses and cancer. Nat. Rev. Immunol. 1:41-49.
13. Cooley, S., F. Xiao, M. Pitt, M. Gleason, V. McCullar, T. L. Bergemann, K. L. McQueen, L. A. Guethlein, P. Parham, and J. S. Miller. 2007. A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature. Blood 110:578-586.
14. Daniels, K. A., G. Devora, W. C. Lai, C. L. O'Donnell, M. Bennett, and R. M. Welsh. 2001. Murine cytomegalovirus is regulated by a discrete subset of natural killer cells reactive with monoclonal antibody to Ly49H. J. Exp. Med. 194:29-44.
15. Desrosiers, M. P., A. Kielczewska, J. C. Loredo-Osti, S. G. Adam, A. P. Makrigiannis, S. Lemieux, T. Pham, M. B. Lodoen, K. Morgan, L. L. Lanier, and S. M. Vidal. 2005. Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infection. Nat. Genet. 37:593-599.
16. Dokun, A. O., S. Kim, H. R. Smith, H. S. Kang, D. T. Chu, and W. M. Yokoyama. 2001. Specific and nonspecific NK cell activation during virus infection. Nat. Immunol. 2:951-956.
17. Fernandez, N. C., E. Treiner, R. E. Vance, A. M. Jamieson, S. Lemieux, and D. H. Raulet. 2005. A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood 105:4416-4423. (Pubitemid 40720789)
18. Fogli, M., P. Costa, G. Murdaca, M. Setti, M. C. Mingari, L. Moretta, A. Moretta, and A. De Maria. 2004. Significant NK cell activation associated with decreased cytolytic function in peripheral blood of HIV-1-infected patients. Eur. J. Immunol. 34:2313-2321.
19. Galiani, M. D., E. Aguado, R. Tarazona, P. Romero, I. Molina, M. Santamaria, R. Solana, and J. Pena. 1999. Expression of killer inhibitory receptors on cytotoxic cells from HIV-1-infected individuals. Clin. Exp. Immunol. 115:472-476.
20. Gandhi, R. T., and B. D. Walker. 2002. Immunologic control of HIV-1. Annu. Rev. Med. 53:149-172.
21. Gardiner, C. M., L. A. Guethlein, H. G. Shilling, M. Pando, W. H. Carr, R. Rajalingam, C. Vilches, and P. Parham. 2001. Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism. J. Immunol. 166:2992-3001. (Pubitemid 33117294)
22. Khakoo, S. I., C. L. Thio, M. P. Martin, C. R. Brooks, X. Gao, J. Astemborski, J. Cheng, J. J. Goedert, D. Vlahov, M. Hilgartner, S. Cox, A. M. Little, G. J. Alexander, M. E. Cramp, S. J. O'Brien, W. M. Rosenberg, D. L. Thomas, and M. Carrington. 2004. HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection. Science 305:872-874. (Pubitemid 39038423)
23. Kim, S., J. Poursine-Laurent, S. M. Truscott, L. Lybarger, Y. J. Song, L. Yang, A. R. French, J. B. Sunwoo, S. Lemieux, T. H. Hansen, and W. M. Yokoyama. 2005. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436:709-713. (Pubitemid 41117274)
24. Kim, S., J. B. Sunwoo, L. Yang, T. Choi, Y. J. Song, A. R. French, A. Vlahiotis, J. F. Piccirillo, M. Cella, M. Colonna, T. Mohanakumar, K. C. Hsu, B. Dupont, and W. M. Yokoyama. 2008. HLA alleles determine differences in human natural killer cell responsiveness and potency. Proc. Natl. Acad. Sci. USA 105:3053-3058.
25. Koup, R. A., J. T. Safrit, Y. Cao, C. A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D. D. Ho. 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68:4650-4655.
26. Lanier, L. L. 1998. NK cell receptors. Annu. Rev. Immunol. 16:359-393.
27. Lanier, L. L. 2005. NK cell recognition. Annu. Rev. Immunol. 23:225-274.
28. Lee, S. H., S. Girard, D. Macina, M. Busa, A. Zafer, A. Belouchi, P. Gros, and S. M. Vidal. 2001. Susceptibility to mouse cytomegalovirus is associated with deletion of an activating natural killer cell receptor of the C-type lectin superfamily. Nat. Genet. 28:42-45.
29. Martin, M. P., X. Gao, J. H. Lee, G. W. Nelson, R. Detels, J. J. Goedert, S. Buchbinder, K. Hoots, D. Vlahov, J. Trowsdale, M. Wilson, S. J. O'Brien, and M. Carrington. 2002. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat. Genet. 31:429-434.
30. Martin, M. P., Y. Qi, X. Gao, E. Yamada, J. N. Martin, F. Pereyra, S. Colombo, E. E. Brown, W. L. Shupert, J. Phair, J. J. Goedert, S. Buchbinder, G. D. Kirk, A. Telenti, M. Connors, S. J. O'Brien, B. D. Walker, P. Parham, S. G. Deeks, D. W. McVicar, and M. Carrington. 2007. Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat. Genet. 39:733-740.
31. Mavilio, D., J. Benjamin, M. Daucher, G. Lombardo, S. Kottilil, M. A. Planta, E. Marcenaro, C. Bottino, L. Moretta, A. Moretta, and A. S. Fauci. 2003. Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates. Proc. Natl. Acad. Sci. USA 100:15011-15016.
32. O'Connor, G. M., K. J. Guinan, R. T. Cunningham, D. Middleton, P. Parham, and C. M. Gardiner. 2007. Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells. J. Immunol. 178:235-241. (Pubitemid 46033606)
33. Orange, J. S., M. S. Fassett, L. A. Koopman, J. E. Boyson, and J. L. Strominger. 2002. Viral evasion of natural killer cells. Nat. Immunol. 3:1006-1012.
34. Picker, L. J. 2006. Immunopathogenesis of acute AIDS virus infection. Curr. Opin. Immunol. 18:399-405.
35. Schmitz, J. E., M. J. Kuroda, S. Santra, V. G. Sasseville, M. A. Simon, M. A. Lifton, P. Racz, K. Tenner-Racz, M. Dalesandro, B. J. Scallon, J. Ghrayeb, M. A. Forman, D. C. Montefiori, E. P. Rieber, N. L. Letvin, and K. A. Reimann. 1999. Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. Science 283:857-860. (Pubitemid 129501128)
36. Trundley, A., H. Frebel, D. Jones, C. Chang, and J. Trowsdale. 2007. Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies. Eur. J. Immunol. 37:780-787.
37. Yawata, M., N. Yawata, M. Draghi, A. M. Little, F. Partheniou, and P. Parham. 2006. Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function. J. Exp. Med. 203:633-645.