Skewed maturation of memory HIV-specific CD8 T lymphocytes

Nature

Volumn 410, Issue 6824, 2001, Pages 106-111

  Champagne, Patrick ^a,b,c   Ogg, Graham S ^d   King, Abigail S ^d   Knabenhans, Christian ^a   Ellefsen, Kim ^a   Nobile, Massimo ^a   Appay, Victor ^d   Rizzardi, G Paolo ^a   Fleury, Sylvain ^a   Lipp, Martin ^e   Förster, Reinhold ^e   Rowland Jones, Sarah ^d   Sékaly, Rafick P ^b,c,f   McMichael, Andrew J ^d   Pantaleo, Giuseppe ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^f UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR7; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CELL DIVISION; CELL MATURATION; CLINICAL ARTICLE; CYTOMEGALOVIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MEMORY CELL; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

ADULT; ANTIGENS, CD45; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CELL LINEAGE; CYTOMEGALOVIRUS; EPITOPES, T-LYMPHOCYTE; HIV; HIV INFECTIONS; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INTERFERON TYPE II; LEUKOPOIESIS; MEMBRANE GLYCOPROTEINS; PORE FORMING CYTOTOXIC PROTEINS; RECEPTORS, CHEMOKINE; T-LYMPHOCYTE SUBSETS;

CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0035282444     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35065118     Document Type: Article

References (26)

1. Lymphocyte homing and homeostasis
2. The role of chemokine receptors in primary, effector, and memory immune responses
3. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
4. + T cells with a predominant V beta usage during the primary immune response to HIV
5. + lymphocytes
6. + T cells produce antiviral cytokines but are impaired in cytolytic function
7. Phenotypic analysis of antigen-specific T lymphocytes
8. Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA
9. HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes
10. Lifespan of human lymphocyte subsets defined by CD45 isoforms
11. + T cells during the primary immune response to Epstein-Barr Virus in vivo
12. + T cells
13. Determination of lymphocyte division by flow cytometry
14. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
15. + T cell population
16. + T lymphocytes of patients with AIDS maintain normal broad cytolytic function despite the loss of human immunodeficiency virus-specific cytotoxicity
17. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells
18. The human cytotoxic T-lymphocyte (CTL) response to Cytomegalovirus is dominated by structural protein pp65: Frequency, specificity, and T-cell receptor usage of pp65-specific CTL
19. + T-cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy
20. Long-term kinetics of T cell production in HIV-infected subjects treated with highly active antiretroviral therapy
21. Perforin is not co-expressed with Granzyme A within cytoxic granules in CD8 T lymphocytes present in lymphoid tissue during chronic HIV infection
22. + T cell turnover
23. Immunology taught by viruses
24. + T cell responses associated with control of viremia
25. Changing virus-host interactions in the course of HIV-1 infection