Antibodies attenuate the capacity of dendritic cells to stimulate HIV-specific cytotoxic T lymphocytes

Journal of Allergy and Clinical Immunology

Volumn 130, Issue 6, 2012, Pages 1368-1374.e2

  Posch, Wilfried ^a   Cardinaud, Sylvain ^b   Hamimi, Chiraz ^c   Fletcher, Adam ^d   Mühlbacher, Annelies ^a   Loacker, Klaus ^a   Eichberger, Paul ^a   Dierich, Manfred P ^a   Pancino, Gianfranco ^c   Lass Flörl, Cornelia ^a   Moris, Arnaud ^b   Saez Cirion, Asier ^c   Wilflingseder, Doris ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b INSERM   (France)

^c INSTITUT PASTEUR   (France)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

cytotoxic T lymphocytes; dendritic cells; HIV; IgG; opsonization

Indexed keywords

ANTIBODY; COMPLEMENT; GAMMA INTERFERON; IMMUNOGLOBULIN G;

ANTIGEN PRESENTING CELL; ANTIVIRAL ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CLONE; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO SELECTION; IN VITRO STUDY; INCUBATION TEMPERATURE; LYMPHOCYTE PROLIFERATION; OPSONIZATION; PLASMA; PRIORITY JOURNAL;

EID: 84870291347     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.08.025     Document Type: Article

References (47)

1. R.A. Koup, J.T. Safrit, Y. Cao, C.A. Andrews, G. McLeod, and W. Borkowsky Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome J Virol 68 1994 4650 4655
2. P. Borrow, H. Lewicki, B.H. Hahn, G.M. Shaw, and M.B. Oldstone Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection J Virol 68 1994 6103 6110
3. A.J. McMichael, and S.L. Rowland-Jones Cellular immune responses to HIV Nature 410 2001 980 987
4. G.J. Freeman, E.J. Wherry, R. Ahmed, and A.H. Sharpe Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade J Exp Med 203 2006 2223 2227
5. M.J. Lewis, M. Dagarag, B. Khan, A. Ali, and O.O. Yang Partial escape of HIV-1 from cytotoxic T lymphocytes during chronic infection J Virol 86 2012 7459 7463
6. A. Saez-Cirion, G. Pancino, M. Sinet, A. Venet, and O. Lambotte HIV controllers: how do they tame the virus? Trends Immunol 28 2007 532 540
7. O. Lambotte, F. Boufassa, Y. Madec, A. Nguyen, C. Goujard, and L. Meyer HIV controllers: a homogeneous group of HIV-1-infected patients with spontaneous control of viral replication Clin Infect Dis 41 2005 1053 1056
8. A. Saez-Cirion, C. Lacabaratz, O. Lambotte, P. Versmisse, A. Urrutia, and A. Boufassa HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype Proc Natl Acad Sci U S A 104 2007 6776 6781
9. S.A. Migueles, C.M. Osborne, C. Royce, A.A. Compton, R.P. Joshi, and K.A. Weeks Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control Immunity 29 2008 1009 1021
10. T. Miura, Z.L. Brumme, M.A. Brockman, P. Rosato, J. Sela, and C.J. Brumme Impaired replication capacity of acute/early viruses in persons who become HIV controllers J Virol 84 2010 7581 7591
11. Z. Banki, W. Posch, A. Ejaz, V. Oberhauser, S. Willey, and C. Gasner Complement as an endogenous adjuvant for dendritic cell-mediated induction of retrovirus-specific CTLs PLoS Pathog 6 2010 e1000891
12. G.D. Tomaras, N.L. Yates, P. Liu, L. Qin, G.G. Fouda, and L.L. Chavez Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia J Virol 82 2008 12449 12463
13. B.F. Haynes, M.A. Moody, H.X. Liao, L. Verkoczy, and G.D. Tomaras B cell responses to HIV-1 infection and vaccination: pathways to preventing infection Trends Mol Med 17 2011 108 116
14. K.J. Bar, H. Li, A. Chamberland, C. Tremblay, J.P. Routy, and T. Grayson Wide variation in the multiplicity of HIV-1 infection among injection drug users J Virol 84 2010 6241 6247
15. C. Moog, H.J. Fleury, I. Pellegrin, A. Kirn, and A.M. Aubertin Autologous and heterologous neutralizing antibody responses following initial seroconversion in human immunodeficiency virus type 1-infected individuals J Virol 71 1997 3734 3741
16. E.S. Gray, M.A. Moody, C.K. Wibmer, X. Chen, D. Marshall, and J. Amos Isolation of a monoclonal antibody that targets the alpha-2 helix of gp120 and represents the initial autologous neutralizing-antibody response in an HIV-1 subtype C-infected individual J Virol 85 2011 7719 7729
17. Y. Cao, L. Qin, L. Zhang, J. Safrit, and D.D. Ho Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection N Engl J Med 332 1995 201 208
18. D.C. Montefiori, G. Pantaleo, L.M. Fink, J.T. Zhou, J.Y. Zhou, and M. Bilska Neutralizing and infection-enhancing antibody responses to human immunodeficiency virus type 1 in long-term nonprogressors J Infect Dis 173 1996 60 67
19. O. Lambotte, G. Ferrari, C. Moog, N.L. Yates, H.X. Liao, and R.J. parks Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers AIDS 23 2009 897 906
20. S.L. Heath, J.G. Tew, A.K. Szakal, and G.F. Burton Follicular dendritic cells and human immunodeficiency virus infectivity Nature 377 1995 740 744
21. J.J. Jakubik, M. Saifuddin, D.M. Takefman, and G.T. Spear Immune complexes containing human immunodeficiency virus type 1 primary isolates bind to lymphoid tissue B lymphocytes and are infectious for T lymphocytes J Virol 74 2000 552 555
22. V. Holl, M. Peressin, T. Decoville, S. Schmidt, S. Zolla-Pazner, and A.M. Aubertin Nonneutralizing antibodies are able to inhibit human immunodeficiency virus type 1 replication in macrophages and immature dendritic cells J Virol 80 2006 6177 6181
23. D. Wilflingseder, Z. Banki, E. Garcia, M. Pruenster, G. Pfister, and B. Muellauer IgG opsonization of HIV impedes provirus formation in and infection of dendritic cells and subsequent long-term transfer to T cells J Immunol 178 2007 7840 7848
24. M. Purtscher, A. Trkola, G. Gruber, A. Burchacher, R. Predl, and F. Steindl A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1 AIDS Res Hum Retroviruses 10 1994 1651 1658
25. N. Casartelli, F. Guivel-Benhassine, R. Bouziat, S. Brandler, O. Schwartz, and A. Moris The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells J Exp Med 207 2010 39 49
26. A. Moris, C. Nobile, F. Buseyne, F. Porrot, J.P. Abastado, and O. Schwartz DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation Blood 103 2004 2648 2654
27. E. Garcia, M. Pion, A. Pelchen-Matthews, L. Collinson, J.F. Arrighi, and G. Blot HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse Traffic 6 2005 488 501
28. H. Bouhlal, N. Chomont, N. Haeffner-Cavaillon, M.D. Kazatchkine, L. Belec, and H. Hocini Opsonization of HIV-1 by semen complement enhances infection of human epithelial cells J Immunol 169 2002 3301 3306
29. Z. Banki, L. Kacani, P. Rusert, M. Pruenster, D. Wilflingseder, and B. Falkensammber Complement dependent trapping of infectious HIV in human lymphoid tissues AIDS 19 2005 481 486
30. B. Heyman The immune complex: possible ways of regulating the antibody response Immunol Today 11 1990 310 313
31. Y. Tanaka, S. Koido, M. Ohana, C. Liu, and J. Gong Induction of impaired antitumor immunity by fusion of MHC class II-deficient dendritic cells with tumor cells J Immunol 174 2005 1274 1280
32. S.J. Turley, K. Inaba, W.S. Garrett, M. Ebersold, J. Unternaehrer, and R.M. Steinman Transport of peptide-MHC class II complexes in developing dendritic cells Science 288 2000 522 527
33. M.B. Lutz, N. Kukutsch, A.L. Ogilvie, S. Rössner, F. Koch, and N. Romani An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow J Immunol Methods 223 1999 77 92
34. K. Rafiq, A. Bergtold, and R. Clynes Immune complex-mediated antigen presentation induces tumor immunity J Clin Invest 110 2002 71 79
35. A. Regnault, D. Lankar, V. Lacabanne, A. Rodriguez, C. Théry, and M. Rescigno Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization J Exp Med 189 1999 371 380
36. M. Carrington, and S.J. O'Brien The influence of HLA genotype on AIDS Annu Rev Med 54 2003 535 551
37. P.J. Goulder, and D.I. Watkins Impact of MHC class I diversity on immune control of immunodeficiency virus replication Nat Rev Immunol 8 2008 619 630
38. H. Streeck, J.S. Jolin, Y. Qi, B. Yassine-Diab, R.C. Johnson, and D.S. Kwon Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells J Virol 83 2009 7641 7648
39. J.M. Andrieu, and W. Lu A dendritic cell-based vaccine for treating HIV infection: background and preliminary results J Intern Med 261 2007 123 131
40. M.J. McElrath, and B.F. Haynes Induction of immunity to human immunodeficiency virus type-1 by vaccination Immunity 33 2010 542 554
41. L.J. Picker, S.G. Hansen, and J.D. Lifson New paradigms for HIV/AIDS vaccine development Annu Rev Med 63 2012 95 111
42. S.P. Buchbinder, D.V. Mehrotra, A. Duerr, D.W. Fitzgerald, R. Mogg, and D. Li Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial Lancet 372 2008 1881 1893
43. M.J. McElrath, S.C. De Rosa, Z. Moodie, S. Dubey, L. Kierstead, and H. Janes HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis Lancet 372 2008 1894 1905
44. N.M. Flynn, D.N. Forthal, C.D. Harro, F.N. Judson, K.H. Mayer, and M.F. Para Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection J Infect Dis 191 2005 654 665
45. P. Pitisuttithum, P. Gilbert, M. Gurwith, W. Heyward, M. Martin, and F. van Griensven Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok Thailand. J Infect Dis 194 2006 1661 1671
46. S. Rerks-Ngarm, P. Pitisuttithum, S. Nitayaphan, J. Kaewkungwal, J. Chiu, and R. Paris Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand N Engl J Med 361 2009 2209 2220
47. M.J. McElrath Immune responses to HIV vaccines and potential impact on control of acute HIV-1 infection J Infect Dis 202 suppl 2 2010 S323 S326