Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection

Blood

Volumn 120, Issue 17, 2012, Pages 3466-3477

  Trautmann, Lydie ^a,b   Mbitikon Kobo, Florentin Martial ^a   Goulet, Jean Philippe ^c   Peretz, Yoav ^d   Shi, Yu ^a   Van Grevenynghe, Julien ^a   Procopio, Francesco Andrea ^a   Boulassel, Mohamad Rachid ^e   Routy, Jean Pierre ^e   Chomont, Nicolas ^a,b   Haddad, Elias K ^a,b   Sekaly, Rafick Pierre ^a,b  

^a Vaccine and Gene Therapy Institute of Florida   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d Caprion/ImmuneCarta Services   (Canada)

^e ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 7; STAT5 PROTEIN;

APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CELL MEDIATED CYTOTOXICITY; CELL METABOLISM; CELL STRESS; CELL SURVIVAL; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSTIMULATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 84868534523     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-04-422550     Document Type: Article

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