HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity

PLoS Pathogens

Volumn 6, Issue 2, 2010, Pages

  Vingert, Benoît ^a   Perez Patrigeon, Santiago ^a   Jeannin, Patricia ^a   Lambotte, Olivier ^b,c,d   Boufassa, Faroudy ^c   Lemaître, Fabrice ^a,e   Kwok, William W ^f   Theodorou, Ioannis ^g   Delfraissy, Jean François ^b,c,d   Théze, Jacques ^a   Chakrabarti, Lisa A ^a  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c BICÊTRE HOSPITAL   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e INSTITUT PASTEUR   (France)

^f BENAROYA RESEARCH INSTITUTE   (United States)

^g PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIGEN; GAG ANTIGEN; GAMMA INTERFERON; HLA DR ANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; GAG PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; EFFECTOR CELL; GENE FREQUENCY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY T LYMPHOCYTE; PHENOTYPE; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; VIREMIA; VIRUS LOAD; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; VIROLOGY;

CD4-POSITIVE T-LYMPHOCYTES; GENE PRODUCTS, GAG; HIV; HIV INFECTIONS; HUMANS; LYMPHOCYTE ACTIVATION; RECEPTORS, ANTIGEN, T-CELL; VIRAL LOAD;

EID: 77649245149     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000780     Document Type: Article

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