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Volumn 122, Issue 9, 2012, Pages 3271-3280

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; GAMMA INTERFERON; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN G1; INTERLEUKIN 21; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN BCL 6; TUMOR NECROSIS FACTOR ALPHA;

EID: 84865997747     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI64314     Document Type: Article
Times cited : (359)

References (51)
  • 1
    • 63149142646 scopus 로고    scopus 로고
    • B cells in HIV infection and disease
    • Moir S, Fauci AS. B cells in HIV infection and disease. Nat Rev Immunol. 2009;9(4):235-245.
    • (2009) Nat Rev Immunol , vol.9 , Issue.4 , pp. 235-245
    • Moir, S.1    Fauci, A.S.2
  • 5
    • 0022545415 scopus 로고
    • Direct polyclonal activation of human B lymphocytes by the acquired immune deficiency syndrome virus
    • Schnittman SM, Lane HC, Higgins SE, Folks T, Fauci AS. Direct polyclonal activation of human B lymphocytes by the acquired immune deficiency syndrome virus. Science. 1986;233(4768):1084-1086. (Pubitemid 16032239)
    • (1986) Science , vol.233 , Issue.4768 , pp. 1084-1086
    • Schnittman, S.M.1    Lane, H.C.2    Higgins, S.E.3
  • 6
    • 0033178613 scopus 로고    scopus 로고
    • Cutting edge: HIV-1 Tat protein differentially modulates the B cell response of naive, memory, and germinal center B cells
    • Lefevre EA, Krzysiek R, Loret EP, Galanaud P, Richard Y. Cutting edge: HIV-1 Tat protein differentially modulates the B cell response of naive, memory, and germinal center B cells. J Immunol. 1999;163(3):1119-1122. (Pubitemid 29352724)
    • (1999) Journal of Immunology , vol.163 , Issue.3 , pp. 1119-1122
    • Lefevre, E.A.1    Krzysiek, R.2    Loret, E.P.3    Galanaud, P.4    Richard, Y.5
  • 7
    • 33645288761 scopus 로고    scopus 로고
    • Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells
    • Qiao X, He B, Chiu A, Knowles DM, Chadburn A, Cerutti A. Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells. Nat Immunol. 2006;7(3):302-310.
    • (2006) Nat Immunol , vol.7 , Issue.3 , pp. 302-310
    • Qiao, X.1    He, B.2    Chiu, A.3    Knowles, D.M.4    Chadburn, A.5    Cerutti, A.6
  • 9
    • 0034605036 scopus 로고    scopus 로고
    • B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells
    • Moir S, et al. B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells. J Exp Med. 2000;192(5):637-646.
    • (2000) J Exp Med , vol.192 , Issue.5 , pp. 637-646
    • Moir, S.1
  • 11
    • 17844374605 scopus 로고    scopus 로고
    • + T cells in multiple tissues during acute SIV infection
    • DOI 10.1038/nature03501
    • Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature.2005;434(7037):1093-1097. (Pubitemid 40663481)
    • (2005) Nature , vol.434 , Issue.7037 , pp. 1093-1097
    • Mattapallil, J.J.1    Douek, D.C.2    Hill, B.3    Nishimura, Y.4    Martin, M.5    Roederer, M.6
  • 13
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol. 2011;29:621-663.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 14
    • 70049101558 scopus 로고    scopus 로고
    • The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
    • Yu D, et al. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity. 2009;31(3):457-468.
    • (2009) Immunity , vol.31 , Issue.3 , pp. 457-468
    • Yu, D.1
  • 15
    • 80052649061 scopus 로고    scopus 로고
    • Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development
    • Baumjohann D, Okada T, Ansel KM. Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development. J Immunol. 2011;187(5):2089-2092.
    • (2011) J Immunol , vol.187 , Issue.5 , pp. 2089-2092
    • Baumjohann, D.1    Okada, T.2    Ansel, K.M.3
  • 16
    • 74849138095 scopus 로고    scopus 로고
    • Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
    • Simpson N, et al. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum. 2010;62(1):234-244.
    • (2010) Arthritis Rheum , vol.62 , Issue.1 , pp. 234-244
    • Simpson, N.1
  • 17
    • 84859711533 scopus 로고    scopus 로고
    • Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation
    • Kroenke MA, et al. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J Immunol. 2012;188(8):3734-3744.
    • (2012) J Immunol , vol.188 , Issue.8 , pp. 3734-3744
    • Kroenke, M.A.1
  • 18
    • 2942755979 scopus 로고    scopus 로고
    • T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
    • Chtanova T, et al. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J Immunol. 2004;173(1):68-78. (Pubitemid 38797327)
    • (2004) Journal of Immunology , vol.173 , Issue.1 , pp. 68-78
    • Chtanova, T.1    Tangye, S.G.2    Newton, R.3    Frank, N.4    Hodge, M.R.5    Rolph, M.S.6    Mackay, C.R.7
  • 19
    • 38049110981 scopus 로고    scopus 로고
    • Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration
    • Kuchen S, et al. Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration. J Immunol. 2007;179(9):5886-5896.
    • (2007) J Immunol , vol.179 , Issue.9 , pp. 5886-5896
    • Kuchen, S.1
  • 20
    • 73949138822 scopus 로고    scopus 로고
    • Loss of HIV-specific memory B-cells as a potential mechanism for the dysfunction of the humoral immune response against HIV
    • Bussmann BM, Reiche S, Bieniek B, Krznaric I, Ackermann F, Jassoy C. Loss of HIV-specific memory B-cells as a potential mechanism for the dysfunction of the humoral immune response against HIV. Virology. 2010;397(1):7-13.
    • (2010) Virology , vol.397 , Issue.1 , pp. 7-13
    • Bussmann, B.M.1    Reiche, S.2    Bieniek, B.3    Krznaric, I.4    Ackermann, F.5    Jassoy, C.6
  • 21
    • 25844482131 scopus 로고    scopus 로고
    • Perils at mucosal front lines for HIV and SIV and their hosts
    • DOI 10.1038/nri1706
    • Haase AT. Perils at mucosal front lines for HIV and SIV and their hosts. Nat Rev Immunol. 2005;5(10):783-792. (Pubitemid 41400852)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.10 , pp. 783-792
    • Haase, A.T.1
  • 24
    • 84863395948 scopus 로고    scopus 로고
    • How can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development?
    • Klasse PJ, Sanders RW, Cerutti A, Moore JP. How can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development? AIDS Res Hum Retroviruses. 2012;28(1):1-15.
    • (2012) AIDS Res Hum Retroviruses , vol.28 , Issue.1 , pp. 1-15
    • Klasse, P.J.1    Sanders, R.W.2    Cerutti, A.3    Moore, J.P.4
  • 26
    • 58149517700 scopus 로고    scopus 로고
    • Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals
    • Li Y, et al. Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals. J Virol. 2009;83(2):1045-1059.
    • (2009) J Virol , vol.83 , Issue.2 , pp. 1045-1059
    • Li, Y.1
  • 27
    • 56449131391 scopus 로고    scopus 로고
    • Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C
    • Binley JM, et al. Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C. J Virol. 2008;82(23):11651- 11668.
    • (2008) J Virol , vol.82 , Issue.23 , pp. 11651-11668
    • Binley, J.M.1
  • 28
    • 69549126129 scopus 로고    scopus 로고
    • Specificity of the autologous neutralizing antibody response
    • Moore PL, Gray ES, Morris L. Specificity of the autologous neutralizing antibody response. Curr Opin HIV AIDS. 2009;4(5):358-363.
    • (2009) Curr Opin HIV AIDS , vol.4 , Issue.5 , pp. 358-363
    • Moore, P.L.1    Gray, E.S.2    Morris, L.3
  • 29
    • 0024330807 scopus 로고
    • Altered IgG-subclass distribution in lymph node cells and serum of adults infected with human immunodeficiency virus (HIV)
    • Muller F, Froland SS, Brandtzaeg P. Altered IgG-subclass distribution in lymph node cells and serum of adults infected with human immunodeficiency virus (HIV). Clin Exp Immunol. 1989;78(2):153-158. (Pubitemid 20009835)
    • (1989) Clinical and Experimental Immunology , vol.78 , Issue.2 , pp. 153-158
    • Muller, F.1    Froland, S.S.2    Brandtzaeg, P.3
  • 30
    • 0022645565 scopus 로고
    • Serum immunoglobulin G subclass dysbalances in the lymphadenopathy syndrome and acquired immune deficiency syndrome
    • Aucouturier P, et al. Serum immunoglobulin G subclass dysbalances in the lymphadenopathy syndrome and acquired immune deficiency syndrome. Clin Exp Immunol. 1986;63(1):234-240. (Pubitemid 16196425)
    • (1986) Clinical and Experimental Immunology , vol.63 , Issue.1 , pp. 234-240
    • Aucouturier, P.1    Couderc, L.J.2    Gouet, D.3
  • 32
    • 27644452293 scopus 로고    scopus 로고
    • Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus
    • Cappione A 3rd, et al. Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus. J Clin Invest. 2005;115(11):3205-3216.
    • (2005) J Clin Invest , vol.115 , Issue.11 , pp. 3205-3216
    • Cappione III, A.1
  • 34
    • 62849126473 scopus 로고    scopus 로고
    • The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
    • Fazilleau N, McHeyzer-Williams LJ, Rosen H, McHeyzer-Williams MG. The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nat Immunol. 2009;10(4):375-384.
    • (2009) Nat Immunol , vol.10 , Issue.4 , pp. 375-384
    • Fazilleau, N.1    McHeyzer-Williams, L.J.2    Rosen, H.3    McHeyzer-Williams, M.G.4
  • 36
    • 84865395104 scopus 로고    scopus 로고
    • CD4 T follicular helper cell dynamics during SIV infection
    • Petrovas C, et al. CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest. 2012;122(9):3281-3294.
    • (2012) J Clin Invest , vol.122 , Issue.9 , pp. 3281-3294
    • Petrovas, C.1
  • 38
    • 77149122105 scopus 로고    scopus 로고
    • IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
    • Linterman MA, et al. IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses. J Exp Med. 2010;207(2):353-363.
    • (2010) J Exp Med , vol.207 , Issue.2 , pp. 353-363
    • Linterman, M.A.1
  • 39
    • 79961151137 scopus 로고    scopus 로고
    • Foxp3+ follicular regulatory T cells control the germinal center response
    • Linterman MA, et al. Foxp3+ follicular regulatory T cells control the germinal center response. Nat Med. 2011;17(8):975-982.
    • (2011) Nat Med , vol.17 , Issue.8 , pp. 975-982
    • Linterman, M.A.1
  • 40
    • 79961158055 scopus 로고    scopus 로고
    • Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
    • Chung Y, et al. Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat Med. 2011;17(8):983-988.
    • (2011) Nat Med , vol.17 , Issue.8 , pp. 983-988
    • Chung, Y.1
  • 41
    • 33847401590 scopus 로고    scopus 로고
    • + T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7
    • DOI 10.1182/blood-2006-06-031385
    • Malaspina A, et al. Idiopathic CD4+ T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7. Blood. 2007;109(5):2086-2088. (Pubitemid 46348209)
    • (2007) Blood , vol.109 , Issue.5 , pp. 2086-2088
    • Malaspina, A.1    Moir, S.2    Chaitt, D.G.3    Rehm, C.A.4    Kottilil, S.5    Falloon, J.6    Fauci, A.S.7
  • 43
    • 38049101408 scopus 로고    scopus 로고
    • Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5+ T follicular helper cells
    • Bryant VL, et al. Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells. J Immunol. 2007;179(12):8180-8190.
    • (2007) J Immunol , vol.179 , Issue.12 , pp. 8180-8190
    • Bryant, V.L.1
  • 44
    • 67649873285 scopus 로고    scopus 로고
    • Mucosal immunity to HIV: A review of recent literature
    • Shacklett BL. Mucosal immunity to HIV: a review of recent literature. Curr Opin HIV AIDS. 2008;3(5):541-547.
    • (2008) Curr Opin HIV AIDS , vol.3 , Issue.5 , pp. 541-547
    • Shacklett, B.L.1
  • 46
    • 73949084963 scopus 로고    scopus 로고
    • Breadth of human immunodeficiency virus-specific neutralizing activity in sera: Clustering analysis and association with clinical variables
    • Doria-Rose NA, et al. Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables. J Virol. 2010;84(3):1631-1636.
    • (2010) J Virol , vol.84 , Issue.3 , pp. 1631-1636
    • Doria-Rose, N.A.1
  • 47
    • 77954943648 scopus 로고    scopus 로고
    • Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
    • Zhou T, et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science. 2010;329(5993):811-817.
    • (2010) Science , vol.329 , Issue.5993 , pp. 811-817
    • Zhou, T.1
  • 48
    • 77954982131 scopus 로고    scopus 로고
    • Crystal structure of PG16 and chimeric dissection with somatically related PG9: Structure-function analysis of two quaternaryspecific antibodies that effectively neutralize HIV-1
    • Pancera M, et al. Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternaryspecific antibodies that effectively neutralize HIV-1. J Virol. 2010;84(16):8098-8110.
    • (2010) J Virol , vol.84 , Issue.16 , pp. 8098-8110
    • Pancera, M.1
  • 49
    • 84857751302 scopus 로고    scopus 로고
    • HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome
    • Soghoian DZ, et al. HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome. Sci Transl Med. 2012;4(123):123ra125.
    • (2012) Sci Transl Med , vol.4 , Issue.123
    • Soghoian, D.Z.1
  • 50
    • 78649516786 scopus 로고    scopus 로고
    • HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function
    • Chevalier MF, et al. HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function. J Virol. 2011;85(2):733-741.
    • (2011) J Virol , vol.85 , Issue.2 , pp. 733-741
    • Chevalier, M.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.