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Volumn 33, Issue 5, 2014, Pages 1239-1260

Integrating omics technologies to study pulmonary physiology and pathology at the systems level

Author keywords

ChIP Seq; Diseasosomes; Epigenomics; Genomics; Interactomes; Network Biology; Proteomics; RNA Seq; Systems Biology; Transcriptomes

Indexed keywords

PROTEOME;

EID: 84899591828     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000358693     Document Type: Review
Times cited : (16)

References (216)
  • 4
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: A brief overview
    • DOI 10.1126/science.1069492
    • Kitano H: Systems biology: A brief overview. Science 2002;295:1662-1664. (Pubitemid 34202893)
    • (2002) Science , vol.295 , Issue.5560 , pp. 1662-1664
    • Kitano, H.1
  • 5
    • 19344372271 scopus 로고    scopus 로고
    • Systems biology: Its practice and challenges
    • DOI 10.1016/j.cell.2005.04.020, PII S0092867405004009
    • Aderem A: Systems biology: Its practice and challenges. Cell 2005;121:511-513. (Pubitemid 40720005)
    • (2005) Cell , vol.121 , Issue.4 , pp. 511-513
    • Aderem, A.1
  • 6
    • 19344375343 scopus 로고    scopus 로고
    • The meaning of systems biology
    • DOI 10.1016/j.cell.2005.05.005, PII S0092867405004472
    • Kirschner MW: The meaning of systems biology. Cell 2005;121:503-504. (Pubitemid 40720002)
    • (2005) Cell , vol.121 , Issue.4 , pp. 503-504
    • Kirschner, M.W.1
  • 8
    • 80051706627 scopus 로고    scopus 로고
    • Aspen lung conference 2010: Systems biology oflung diseases-progress in the omics era
    • Sheppard D: Aspen lung conference 2010: Systems biology oflung diseases-progress in the omics era. Proc Am Thorac Soc 2011;8:199-202.
    • (2011) Proc Am Thorac Soc , vol.8 , pp. 199-202
    • Sheppard, D.1
  • 9
    • 77953303583 scopus 로고    scopus 로고
    • An integrative systems biology approach to understanding pulmonary diseases
    • Auffray C, Adcock IM, Chung KF, Djukanovic R, Pison C, Sterk PJ: An integrative systems biology approach to understanding pulmonary diseases. Chest 2010;137:1410-1416.
    • (2010) Chest , vol.137 , pp. 1410-1416
    • Auffray, C.1    Adcock, I.M.2    Chung, K.F.3    Djukanovic, R.4    Pison, C.5    Sterk, P.J.6
  • 10
    • 79959362446 scopus 로고    scopus 로고
    • Complex systems in pulmonary medicine: A systems biology approach to lung disease
    • Kaminsky DA, Irvin CG, Sterk PJ: Complex systems in pulmonary medicine: A systems biology approach to lung disease. J Appl Physiol 2011;110:1716-1722.
    • (2011) J Appl Physiol , vol.110 , pp. 1716-1722
    • Kaminsky, D.A.1    Irvin, C.G.2    Sterk, P.J.3
  • 16
    • 84874100891 scopus 로고    scopus 로고
    • Screening of differentially expressed gen es and small molecule drugs of pediatric allergic asthma with DNA microarray
    • Wang XQ, Wang XM, Zhou TF, Dong LQ: Screening of differentially expressed gen es and small molecule drugs of pediatric allergic asthma with DNA microarray. Eur Rev Med Pharmacol Sci 2012;16:1961-1966.
    • (2012) Eur Rev Med Pharmacol Sci , vol.16 , pp. 1961-1966
    • Wang, X.Q.1    Wang, X.M.2    Zhou, T.F.3    Dong, L.Q.4
  • 17
    • 84877155246 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease genomics: Yesterday, discovering population biomarkers; Tomorrow, defining disease clusters
    • Mariani TJ Martinez F Chronic obstructive pulmonary disease genomics: Yesterday, discovering population biomarkers; tomorrow, defining disease clusters Am JRespir Crit Care Med 2013 187 900-902
    • (2013) Am JRespir Crit Care Med , vol.187 , pp. 900-902
    • Mariani, T.J.1    Martinez, F.2
  • 20
    • 38849107498 scopus 로고    scopus 로고
    • Reversible and permanent effects of tobacco smoke ex posure on airway epithelial gene expression
    • Beane J, Sebastiani P, Liu G, Brody JS, Lenburg ME, Spira A: Reversible and permanent effects of tobacco smoke ex posure on airway epithelial gene expression. Genome Biology 2007;8:R201.
    • (2007) Genome Biology , vol.8 , pp. 201
    • Beane, J.1    Sebastiani, P.2    Liu, G.3    Brody, J.S.4    Lenburg, M.E.5    Spira, A.6
  • 26
    • 34547620666 scopus 로고    scopus 로고
    • Progress toward a systems biology approach to acute lung injury
    • Frank JA, Erie DJ: Progress toward a systems biology approach to acute lung injury. Am J Physiol Lun g Cell Mol Physiol 2007;293:L290-291.
    • (2007) Am J Physiol Lun G Cell Mol Physiol , vol.293 , pp. 290-291
    • Frank, J.A.1    Erie, D.J.2
  • 27
    • 84878593825 scopus 로고    scopus 로고
    • Dna microarray-based screening of differentially expressed genes related to acute lung injury and functional analysis
    • ChenY, Shi JX, PanXF, Feng J, Zhao H: DNA microarray-based screening of differentially expressed genes related to acute lung injury and functional analysis. Eur Rev Med Pharmac ol Sci 2013;17:1044-1050.
    • (2013) Eur Rev Med Pharmac Ol Sci , vol.17 , pp. 1044-1050
    • Chen, Y.1    Shi, J.X.2    Pan, X.F.3    Feng, J.4    Zhao, H.5
  • 28
    • 44449164317 scopus 로고    scopus 로고
    • Gene expression profiling of non-small cell lung cancer
    • Singhal S, Miller D, Ramalingam S, Sun SY: Gene expression profiling of non-small cell lung cancer. Lung Cancer 2008;60:313-324.
    • (2008) Lung Cancer , vol.60 , pp. 313-324
    • Singhal, S.1    Miller, D.2    Ramalingam, S.3    Sun, S.Y.4
  • 30
    • 84893378509 scopus 로고    scopus 로고
    • Timp-2 modulates cancer cell transcriptional profile and enhances e-cadherin/beta-catenin complex expression in a549 lung cancer cells
    • Bourboulia D, Han H, Jensen-Taubman S, Gavil N, Isaac B, Wei B, Neckers L, Stetler-StevensonWG: Timp-2 modulates cancer cell transcriptional profile and enhances e-cadherin/beta-catenin complex expression in a549 lung cancer cells. Oncotarget 2013;4: 166-176.
    • (2013) Oncotarget , vol.4 , pp. 166-176
    • Bourboulia, D.1    Han, H.2    Jensen-Taubman, S.3    Gavil, N.4    Isaac, B.5    Wei, B.6    Neckers, L.7    Stetler-Stevenson, W.G.8
  • 31
    • 84881479502 scopus 로고    scopus 로고
    • Genome-wide transcriptional analysis of apoptosis-related genes and pathways regulated by h2ax in lung cancer a549 cells
    • LuC, Xiong M, Luo Y, Li J, Zhang Y, Dong Y, Zhu Y, Niu T, Wang Z, Duan L: Genome-wide transcriptional analysis of apoptosis-related genes and pathways regulated by h2ax in lung cancer a549 cells. Apoptosis 2013;18:1039-1047.
    • (2013) Apoptosis , vol.18 , pp. 1039-1047
    • Lu, C.1    Xiong, M.2    Luo, Y.3    Li, J.4    Zhang, Y.5    Dong, Y.6    Zhu, Y.7    Niu, T.8    Wang, Z.9    Duan, L.10
  • 33
    • 65949104586 scopus 로고    scopus 로고
    • Genomew ide association studies and human disease
    • HardyJ, Singleton A: Genomew ide association studies and human disease. N Engl J Med 2009;360:1759-1768.
    • (2009) N Engl J Med , vol.360 , pp. 1759-1768
    • Hardy, J.1    Singleton, A.2
  • 34
    • 84884657684 scopus 로고    scopus 로고
    • Fifty years on: Gwas confirms the role of a rare variant in lung disease
    • Turner AM: Fifty years on: Gwas confirms the role of a rare variant in lung disease. PLoS Genetics 2013;9:el003768.
    • (2013) PLoS Genetics , vol.9
    • Turner, A.M.1
  • 38
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using david bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA: Systematic and integrative analysis of large gene lists using david bioinformatics resources. Nat Protoc 2009;4:44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 39
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis oflarge gene lists
    • Huang da W Sherman BT Lempicki RA: Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis oflarge gene lists. Nucleic Acids Res 2009;37:1-13.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 41
    • 77955801615 scopus 로고    scopus 로고
    • Galaxy: A comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
    • Goecks J, Nekrutenko A, TaylorJ: Galaxy: A comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol 2010;11:R86.
    • (2010) Genome Biol , vol.11 , pp. 86
    • Goecks, J.1    Nekrutenko, A.2    Taylor, J.3
  • 43
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE: Gene expression omnibus: Ncbi gene expression and hybridization array data repository. Nucleic Acids Res 2002;30:207-210. (Pubitemid 34679544)
    • (2002) Nucleic Acids Research , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 49
    • 78549284326 scopus 로고    scopus 로고
    • Involvement of micrornas in physiological and pathological processes inthe lung
    • Tomankova T, Petrek M, Kriegova E: Involvement of micrornas in physiological and pathological processes inthe lung. Respir Res 2010;11:159.
    • (2010) Respir Res , vol.11 , pp. 159
    • Tomankova, T.1    Petrek, M.2    Kriegova, E.3
  • 50
    • 79952781841 scopus 로고    scopus 로고
    • Integrating micrornas into a system biology approach to acute lung injury
    • Zhou T, Garcia JGN, Zhang W: Integrating micrornas into a system biology approach to acute lung injury. Translat Res 2011;157:180-190.
    • (2011) Translat Res , vol.157 , pp. 180-190
    • Zhou, T.1    Garcia, J.G.N.2    Zhang, W.3
  • 51
    • 77958533034 scopus 로고    scopus 로고
    • Micrornas in inflammatory lung disease-master regulators or targetpractice
    • Oglesby IK, McElvaney NG, Greene CM: Micrornas in inflammatory lung disease-master regulators or targetpractice Respir Res 2010;11:148.
    • (2010) Respir Res , vol.11 , pp. 148
    • Oglesby, I.K.1    McElvaney, N.G.2    Greene, C.M.3
  • 52
    • 79960104144 scopus 로고    scopus 로고
    • Micrornas in developmentand disease
    • Sayed D, Abdellatif M: Micrornas in developmentand disease. Physiol Rev 2011;91:827-887.
    • (2011) Physiol Rev , vol.91 , pp. 827-887
    • Sayed, D.1    Abdellatif, M.2
  • 53
    • 84856044224 scopus 로고    scopus 로고
    • Micrornas in lung diseases
    • Pagdin T, Lavender P: Micrornas in lung diseases. Thorax 2012;67:183-184.
    • (2012) Thorax , vol.67 , pp. 183-184
    • Pagdin, T.1    Lavender, P.2
  • 55
    • 84890402461 scopus 로고    scopus 로고
    • Role of micrornas in lung development and pulmonary diseases
    • Sessa R, Hata A: Role of micrornas in lung development and pulmonary diseases. Pulmonary Circ 2013;3:315-328.
    • (2013) Pulmonary Circ , vol.3 , pp. 315-328
    • Sessa, R.1    Hata, A.2
  • 56
    • 79952790398 scopus 로고    scopus 로고
    • Micrornas in idiopathic pulmonary fibrosis
    • Pandit KV, Milosevic J, Kaminski N: Micrornas in idiopathic pulmonary fibrosis. Transl Res 2011;157:191-199.
    • (2011) Transl Res , vol.157 , pp. 191-199
    • Pandit, K.V.1    Milosevic, J.2    Kaminski, N.3
  • 57
    • 84856711884 scopus 로고    scopus 로고
    • Evolving genomic approaches to idiopathic pulmonary fibrosis: Moving beyond genes
    • Kass DJ, Kaminski N: Evolving genomic approaches to idiopathic pulmonary fibrosis: Moving beyond genes. Clin Transl Sci 2011;4:372-379.
    • (2011) Clin Transl Sci , vol.4 , pp. 372-379
    • Kass, D.J.1    Kaminski, N.2
  • 59
    • 84867635564 scopus 로고    scopus 로고
    • Micrornas as potential biomarkers of smoking-related diseases
    • Banerjee A, Luettich K: Micrornas as potential biomarkers of smoking-related diseases. Biomark Med 2012;6:671-684.
    • (2012) Biomark Med , vol.6 , pp. 671-684
    • Banerjee, A.1    Luettich, K.2
  • 63
    • 84883525890 scopus 로고    scopus 로고
    • Cancer diagnosis and prognosis decoded by blood-based circulating microrna signatures
    • Madhavan D, Cuk K, Burwinkel B, Yang R: Cancer diagnosis and prognosis decoded by blood-based circulating microrna signatures. Front Genet 2013;4:116.
    • (2013) Front Genet , vol.4 , pp. 116
    • Madhavan, D.1    Cuk, K.2    Burwinkel, B.3    Yang, R.4
  • 64
    • 84885730364 scopus 로고    scopus 로고
    • Epigenetic therapy in lung cancer-role of micrornas
    • Rothschild SI: Epigenetic therapy in lung cancer-role of micrornas. Front Oncol 2013;3:158.
    • (2013) Front Oncol , vol.3 , pp. 158
    • Rothschild, S.I.1
  • 66
    • 84890908154 scopus 로고    scopus 로고
    • Mechanistic links between copd and lung cancer: A role of microrna let-7
    • Shin JI, Brusselle GG: Mechanistic links between copd and lung cancer: A role of microrna let-7 Nat Rev Cancer 2014;14:70-70.
    • (2014) Nat Rev Cancer , vol.14 , pp. 70-70
    • Shin, J.I.1    Brusselle, G.G.2
  • 67
    • 84867022383 scopus 로고    scopus 로고
    • Distinct microrna expression in human airway cells of asthmatic donors identifies a novel asthma-associated gene
    • Jardim MJ, Dailey L, Silbajoris R, Diaz-Sanchez D: Distinct microrna expression in human airway cells of asthmatic donors identifies a novel asthma-associated gene. Am J Respir Cell Mol Biol 2012;47:536-542.
    • (2012) Am J Respir Cell Mol Biol , vol.47 , pp. 536-542
    • Jardim, M.J.1    Dailey, L.2    Silbajoris, R.3    Diaz-Sanchez, D.4
  • 69
    • 84882797818 scopus 로고    scopus 로고
    • Targeting translational control as a novel way to treat inflammatory disease: The emerging role of micrornas
    • Plank M, Maltby S, Mattes J, Foster PS: Targeting translational control as a novel way to treat inflammatory disease: The emerging role of micrornas. Clin Exp Allergy 2013;4 3:981-999.
    • (2013) Clin Exp Allergy , vol.43 , pp. 981-999
    • Plank, M.1    Maltby, S.2    Mattes, J.3    Foster, P.S.4
  • 70
    • 84904071424 scopus 로고    scopus 로고
    • Micromanaging micrornas: Using murine models to study micrornas inlungfibrosis
    • doi.org/10.1016/j.ddmod.2012.11.003
    • Lino Cardenas CL, Kaminski N, Kass DJ: Micromanaging micrornas: Using murine models to study micrornas inlungfibrosis. DrugDiscoveryToday: Disease Models doi.org/10.1016/j.ddmod.2012.11.003.
    • DrugDiscoveryToday: Disease Models
    • Lino Cardenas, C.L.1    Kaminski, N.2    Kass, D.J.3
  • 73
    • 84880758429 scopus 로고    scopus 로고
    • Holding our breath: The emerging and anticipated roles of microrna in pulmonaryhypertension
    • White K, Loscalzo J, Chan SY: Holding our breath: The emerging and anticipated roles of microrna in pulmonaryhypertension. PulmonCirc 2012;2:278-290.
    • (2012) PulmonCirc , vol.2 , pp. 278-290
    • White, K.1    Loscalzo, J.2    Chan, S.Y.3
  • 75
    • 84875200060 scopus 로고    scopus 로고
    • Analysis of the nci-60 dataset for cancer-related microrna and mrna using expression profiles
    • We ng C-W, Lee S-C, Lee Y-L, Ng K-L: Analysis of the nci-60 dataset for cancer-related microrna and mrna using expression profiles. Comput Biol Chem 2013;44:15-21.
    • (2013) Comput Biol Chem , vol.44 , pp. 15-21
    • Weng, C.-W.1    Lee, S.-C.2    Lee, Y.-L.3    Ng, K.-L.4
  • 77
    • 84877340215 scopus 로고    scopus 로고
    • Systems biologyapproaches to identify developmental bases for lung diseases
    • Bhattacharya S, Mariani TJ: Systems biologyapproaches to identify developmental bases for lung diseases. Pediatr Res 2013;73:514-522.
    • (2013) Pediatr Res , vol.73 , pp. 514-522
    • Bhattacharya, S.1    Mariani, T.J.2
  • 78
    • 79955498646 scopus 로고    scopus 로고
    • Addressing the complexity of chronic obstructive pulmonary disease: From phenotypes and biomarkers to scale-free networks, systems biology, and p4 medicine
    • Agusti A, Sobradillo P, Ce lli B: Addressing the complexity of chronic obstructive pulmonary disease: From phenotypes and biomarkers to scale-free networks, systems biology, and p4 medicine. Am J Respir Crit Care Med 2011;183:1129-1137.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1129-1137
    • Agusti, A.1    Sobradillo, P.2    Celli, B.3
  • 79
    • 84872112470 scopus 로고    scopus 로고
    • Network medicine approaches to the genetics of complex diseases
    • Sil verman EK, Loscalzo J: Network medicine approaches to the genetics of complex diseases. Discov Med 2012;14:143-152.
    • (2012) Discov Med , vol.14 , pp. 143-152
    • Silverman, E.K.1    Loscalzo, J.2
  • 82
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
    • Le wis BP Burge CB Bartel DP Conserved seed pairing, often flanked by adenosines, indicates that thousands ofhuman genes are microrna targets Cell 2005 120 15-20. (Pubitemid 40094598)
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 83
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
    • DOI 10.1016/j.molcel.2007.06.017, PII S1097276507004078
    • Grimson A, Farh KKH, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP: Microrna targeting specificity in mammals: Determinants beyond seed pairing. Mol Cell 2007;27:91-105. (Pubitemid 46991392)
    • (2007) Molecular Cell , vol.27 , Issue.1 , pp. 91-105
    • Grimson, A.1    Farh, K.K.-H.2    Johnston, W.K.3    Garrett-Engele, P.4    Lim, L.P.5    Bartel, D.P.6
  • 84
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mrnas are conserved targets of micrornas
    • Friedman RC, Farh KK-H, Burge CB, Bartel DP: Most mammalian mrnas are conserved targets of micrornas. Genome Res 2009;19:92-105.
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Kk-H, F.2    Burge, C.B.3    Bartel, D.P.4
  • 88
    • 58149186499 scopus 로고    scopus 로고
    • Mirecords: An integrated resource for microrna-target interactions
    • Xiao F, Zuo Z, Cai G, Kang S, Gao X,LiT: Mirecords: An integrated resource for microrna-target interactions. Nucleic Acids Res 2009;37:D105-110.
    • (2009) Nucleic Acids Res , vol.37 , pp. 105-110
    • Xiao, F.1    Zuo, Z.2    Cai, G.3    Kang, S.4    Gao, X.5    Li, T.6
  • 90
    • 79959805164 scopus 로고    scopus 로고
    • Mirwalk-database: Prediction of possible mirna binding sites by " walking" the genes of three genomes
    • Dweep H, Sticht C, Pandey P, Gretz N: Mirwalk-database: Prediction of possible mirna binding sites by " walking" the genes of three genomes. J Biomed Inform 2011;44:839-847.
    • (2011) J Biomed Inform , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 95
    • 79951849971 scopus 로고    scopus 로고
    • Integrative analysis of next generation sequencing for small non-coding rnas and transcriptional regulation in myelodysplastic syndromes
    • Beck D, Ayers S, Wen J, Brandi MB, Pham TD, Webb P, Chang CC, Zhou X: Integrative analysis of next generation sequencing for small non-coding rnas and transcriptional regulation in myelodysplastic syndromes. BMC Med Genomics 2011;4:19.
    • (2011) BMC Med Genomics , vol.4 , pp. 19
    • Beck, D.1    Ayers, S.2    Wen, J.3    Brandi, M.B.4    Pham, T.D.5    Webb, P.6    Chang, C.C.7    Zhou, X.8
  • 99
    • 84882450872 scopus 로고    scopus 로고
    • Non-coding rna: Structure and function for lncrnas
    • Flintoft L: Non-coding rna: Structure and function for lncrnas. Nature reviews Genetics 2013;14:598.
    • (2013) Nature Reviews Genetics , vol.14 , pp. 598
    • Flintoft, L.1
  • 100
    • 84874622776 scopus 로고    scopus 로고
    • Mechanistic roles of noncoding rnas in lung cancer biology and their clinical implications
    • Enfield KSS, Pikor LA, Martinez VD, Lam WL: Mechanistic roles of noncoding rnas in lung cancer biology and their clinical implications. Genet Res Int 2012;2012:16.
    • (2012) Genet Res Int , vol.2012 , pp. 16
    • Enfield, K.S.S.1    Pikor, L.A.2    Martinez, V.D.3    Lam, W.L.4
  • 101
    • 84900457632 scopus 로고    scopus 로고
    • A network based method for analysis oflncrna-disease associations and prediction oflncrnas implicated in diseases
    • YangX, Gao L, Guo X, ShiX, Wu H, Song F, Wang B: A network based method for analysis oflncrna-disease associations and prediction oflncrnas implicated in diseases. PLoS One 2014;9:e87797.
    • (2014) PLoS One , vol.9
    • Yangx Gao, L.1    Guo, X.2    Shix Wu, H.3    Song, F.4    Wang, B.5
  • 102
    • 84894258048 scopus 로고    scopus 로고
    • A computational frameworkto infer human disease-associated long noncoding rnas
    • Liu M-X, ChenX, Chen G, Cui Q-H, Yan G-Y: A computational frameworkto infer human disease-associated long noncoding rnas. PLoS One 2014;9:e84408.
    • (2014) PLoS One , vol.9
    • Liu, M.-X.1    Chen, X.2    Chen, G.3    Cui, Q.-H.4    Yan, G.-Y.5
  • 103
    • 57749195712 scopus 로고    scopus 로고
    • Rna-seq: A revolutionarytool for transcriptomics
    • Wang Z Gerstein M Snyder M Rna-seq: A revolutionarytool for transcriptomics Nat Rev Genet 2009 10 57-63.
    • (2009) Nat Rev Genet , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 104
    • 84901488220 scopus 로고    scopus 로고
    • Beyond the genome 2012 boston, ma, USA 27-29 September 2012. Abstracts
    • Beyond the genome 2012 boston, ma, USA. 27-29 September 2012. Abstracts. BMC Proc 2012;6:01-P54.
    • (2012) BMC Proc , vol.6
  • 107
    • 84896963559 scopus 로고    scopus 로고
    • Screening of genes related to lung cancer caused by smoking with rna-seq
    • Zhou C, Chen H, Han L, Xue F, Wang A, Liang Y-j: Screening of genes related to lung cancer caused by smoking with rna-seq. Eur Rev Med Pharmacol Sci 2014;18:117-125.
    • (2014) Eur Rev Med Pharmacol Sci , vol.18 , pp. 117-125
    • Zhou, C.1    Chen, H.2    Han, L.3    Xue, F.4    Wang, A.5    Y-J, L.6
  • 109
    • 75249087100 scopus 로고    scopus 로고
    • Edger: A bioconductor package for differential expression analysis of digital gene expression data
    • Robinson MD, McCarthy DJ, Smyth GK: Edger: A bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 2010;26:139-140.
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 110
  • 113
    • 84859203603 scopus 로고    scopus 로고
    • Epigenomics of idiopathic pulmonary fibrosis
    • Yang IV: Epigenomics of idiopathic pulmonary fibrosis. Epigenomics 2012;4:195-203.
    • (2012) Epigenomics , vol.4 , pp. 195-203
    • Yang, I.V.1
  • 115
    • 73649107635 scopus 로고    scopus 로고
    • Epigenetics: Molecular mechanisms and implications for disease
    • Handel AE, Ebers GC, Ramagopalan SV: Epigenetics: Molecular mechanisms and implications for disease. Trends Mol Med 2010;16:7-16.
    • (2010) Trends Mol Med , vol.16 , pp. 7-16
    • Handel, A.E.1    Ebers, G.C.2    Ramagopalan, S.V.3
  • 116
    • 79952202819 scopus 로고    scopus 로고
    • Epigenetics and prenatal influences on asthma and allergic airways disease
    • Martino D, Prescott S: Epigenetics and prenatal influences on asthma and allergic airways disease. Chest 2011;139:640-647.
    • (2011) Chest , vol.139 , pp. 640-647
    • Martino, D.1    Prescott, S.2
  • 117
    • 77955480504 scopus 로고    scopus 로고
    • Epigenetics and environmental lung disease
    • Schwartz DA: Epigenetics and environmental lung disease. Proc Am Thorac Soc 2010;7:123-125.
    • (2010) Proc Am Thorac Soc , vol.7 , pp. 123-125
    • Schwartz, D.A.1
  • 118
    • 84876124887 scopus 로고    scopus 로고
    • Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases
    • Sundar IK, Yao H, Rahman I: Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases. Antioxid Redox Signal 2013;18:1956-1971.
    • (2013) Antioxid Redox Signal , vol.18 , pp. 1956-1971
    • Sundar, I.K.1    Yao, H.2    Rahman, I.3
  • 119
    • 84873967056 scopus 로고    scopus 로고
    • The promise of epigenetic therapies in treatment of idiopathic pulmonary fibrosis
    • Rosas 10
    • Rosas 10, Yang IV: The promise of epigenetic therapies in treatment of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2013;187:336-338.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 336-338
    • Yang, I.V.1
  • 123
    • 79952790398 scopus 로고    scopus 로고
    • Micrornas in idiopathic pulmonary fibrosis
    • Pandit KV, Milosevic J, Kaminski N: Micrornas in idiopathic pulmonary fibrosis. Transl Res 2011;157:191-199.
    • (2011) Transl Res , vol.157 , pp. 191-199
    • Pandit, K.V.1    Milosevic, J.2    Kaminski, N.3
  • 127
    • 84893873979 scopus 로고    scopus 로고
    • Cigarette smoke induces distincthistone modifications in lung cells: Implications for the pathogenesis of copd and lung cancer
    • Sundar IK, Nevid MZ, FriedmanAE, Rahman I: Cigarette smoke induces distincthistone modifications in lung cells: Implications for the pathogenesis of copd and lung cancer. J Proteome Res 2013;13:982-996.
    • (2013) J Proteome Res , vol.13 , pp. 982-996
    • Sundar, I.K.1    Nevid, M.Z.2    Friedman, A.E.3    Rahman, I.4
  • 128
    • 84891149662 scopus 로고    scopus 로고
    • Epigenetics in immune-mediated pulmonary diseases
    • Liu Y, Li H, Xiao T, Lu Q: Epigenetics in immune-mediated pulmonary diseases. Clinic RevAllerg Immunol 2013;45:314-330.
    • (2013) Clinic RevAllerg Immunol , vol.45 , pp. 314-330
    • Liu, Y.1    Li, H.2    Xiao, T.3    Lu, Q.4
  • 129
    • 23044514626 scopus 로고    scopus 로고
    • Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
    • DOI 10.1038/ng1598
    • Weber M, Davies JJ, Wittig D, Oakeley EJ, Haase M, Lam WL, Schubeler D: Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nature Genet 2005;37:853-862. (Pubitemid 41077111)
    • (2005) Nature Genetics , vol.37 , Issue.8 , pp. 853-862
    • Weber, M.1    Davies, J.J.2    Wittig, D.3    Oakeley, E.J.4    Haase, M.5    Lam, W.L.6    Schubeler, D.7
  • 131
    • 79957868920 scopus 로고    scopus 로고
    • Bismark: A flexible aligner and methylation caller for bisulfite-seq applications
    • Krueger F, Andrews SR: Bismark: A flexible aligner and methylation caller for bisulfite-seq applications. Bioinformatics 2011;27:1571-1572.
    • (2011) Bioinformatics , vol.27 , pp. 1571-1572
    • Krueger, F.1    Andrews, S.R.2
  • 137
    • 33747619654 scopus 로고    scopus 로고
    • Proteomics in pulmonary medicine
    • DOI 10.1378/chest.130.2.567
    • Bowler RP, Ellison MC, Reisdorph N: Proteomics in pulmonary medicine. Chest 2006;130:567-574. (Pubitemid 44267028)
    • (2006) Chest , vol.130 , Issue.2 , pp. 567-574
    • Bowler, R.P.1    Ellison, M.C.2    Reisdorph, N.3
  • 138
    • 84934441007 scopus 로고    scopus 로고
    • Proteomic analysis ofthe asthmatic airway
    • in BrasierAR (ed) Springer USA
    • Wiktorowicz J, Jamaluddin M: Proteomic analysis ofthe asthmatic airway; in BrasierAR (ed): Heterogeneity in asthma. Springer USA, 2014, vol 795, pp 221-232.
    • (2014) Heterogeneity in Asthma. , vol.795 , pp. 221-232
    • Wiktorowicz, J.1    Jamaluddin, M.2
  • 142
    • 84874691836 scopus 로고    scopus 로고
    • Proteomic profiling of bronchoalveolar lavage fluid in critically ill patients with ventilator-associated pneumonia
    • Nguy en EV, Gharib SA, Palazzo SJ, ChowYH, Goodlett DR, Schnapp LM: Proteomic profiling of bronchoalveolar lavage fluid in critically ill patients with ventilator-associated pneumonia. PLoS One 2013;8:e58782.
    • (2013) PLoS One , vol.8
    • Nguyen, E.V.1    Gharib, S.A.2    Palazzo, S.J.3    Chow, Y.H.4    Goodlett, D.R.5    Schnapp, L.M.6
  • 143
    • 84876404854 scopus 로고    scopus 로고
    • Towards a functional proteomics approach to the comprehension of idiopathic pulmonary fi brosis, sarcoidosis, systemic sclerosis and pulmonarylangerhans cell histiocytosis
    • Landi C, Bargagli E, Bianchi L, Gagliardi A, Carleo A, Bennett D, Perari MG, Armini A, Prasse A, Rottoli P, Bini L: Towards a functional proteomics approach to the comprehension of idiopathic pulmonary fi brosis, sarcoidosis, systemic sclerosis and pulmonarylangerhans cell histiocytosis. J Proteomics 2013;83:60-75.
    • (2013) J Proteomics , vol.83 , pp. 60-75
    • Landi, C.1    Bargagli, E.2    Bianchi, L.3    Gagliardi, A.4    Carleo, A.5    Bennett, D.6    Perari, M.G.7    Armini, A.8    Prasse, A.9    Rottoli, P.10    Bini, L.11
  • 145
    • 84867762292 scopus 로고    scopus 로고
    • Phosphoproteomics and lung cancer research
    • Lopez E, Cho WC: Phosphoproteomics and lung cancer research. Int J Mol Sci 2012;13:12287-12314.
    • (2012) Mol Sci , vol.13 , pp. 12287-12314
    • Lopez, E.1    Cho, W.C.2
  • 149
    • 33750619876 scopus 로고    scopus 로고
    • Posttranslational protein modifications: Current implications for cancer detection, prevention, and therapeutics
    • DOI 10.1074/mcp.R600009-MCP200
    • Krueger KE, Srivastava S: Posttranslational protein modifications: Current implications for cancer detection, prevention, and therapeutics. Mol Cell Proteom 2006;5:1799-1810. (Pubitemid 44688189)
    • (2006) Molecular and Cellular Proteomics , vol.5 , Issue.10 , pp. 1799-1810
    • Krueger, K.E.1    Srivastava, S.2
  • 150
    • 84890548691 scopus 로고    scopus 로고
    • Introduction to opportunities and pitfalls in functional mass spectrometry based proteomics
    • Vaudel M, Sickmann A, Martens L: Introduction to opportunities and pitfalls in functional mass spectrometry based proteomics. Biochim Biophys Acta 2014;1844:12-20.
    • (2014) Biochim Biophys Acta , vol.1844 , pp. 12-20
    • Vaudel, M.1    Sickmann, A.2    Martens, L.3
  • 159
    • 12944269065 scopus 로고
    • Rapid identification of proteins by peptide-mass fingerprinting
    • Pappin DJ, Hojrup P, BleasbyAJ: Rapid identification of proteins by peptide-mass fingerprinting. Curr Biol 1993;3:327-332.
    • (1993) Curr Biol , vol.3 , pp. 327-332
    • Pappin, D.J.1    Hojrup, P.2    Bleasby, A.J.3
  • 160
    • 0034213595 scopus 로고    scopus 로고
    • ProFound: An expert system for protein identification using mass spectrometric peptide mapping information
    • DOI 10.1021/ac991363o
    • ZhangW, Chait BT: Profound: An expert system for protein identification using mass spectrometric peptide mapping information. Anal Chem 2000;72:2482-2489. (Pubitemid 30395651)
    • (2000) Analytical Chemistry , vol.72 , Issue.11 , pp. 2482-2489
    • Zhang, W.1    Chait, B.T.2
  • 161
    • 0000857494 scopus 로고
    • An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
    • Eng J, McCormackA, Yates J: An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom 1994;5:976-989.
    • (1994) J Am Soc Mass Spectrom , vol.5 , pp. 976-989
    • Eng, J.1    McCormack, A.2    Yates, J.3
  • 162
    • 0033434080 scopus 로고    scopus 로고
    • Probability-based protein identification by searching sequence databases using mass spectrometry data
    • Perkins DN, Pappin DJ, Creasy DM, Cottrell JS: Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 1999;20:3551-3567. (Pubitemid 30007252)
    • (1999) Electrophoresis , vol.20 , Issue.18 , pp. 3551-3567
    • Perkins, D.N.1    Pappin, D.J.C.2    Creasy, D.M.3    Cottrell, J.S.4
  • 164
    • 34848819400 scopus 로고    scopus 로고
    • Comparative evaluation of tandem MS search algorithms using a target-decoy search stategy
    • DOI 10.1074/mcp.M600469-MCP200
    • Balgley BM, Laudeman T, Yang L, Song T, Lee CS: Comparative evaluation of tandem ms search algorithms using a target-decoy search strategy. Mol Cell Proteomics 2007;6:1599-1608. (Pubitemid 47506170)
    • (2007) Molecular and Cellular Proteomics , vol.6 , Issue.9 , pp. 1599-1608
    • Balgley, B.M.1    Laudeman, T.2    Yang, L.3    Song, T.4    Lee, C.S.5
  • 165
    • 79952306399 scopus 로고    scopus 로고
    • Compass: A suite of pre-and post-search proteomics software tools for omssa
    • Wenger CD, Phanstiel DH, Lee MV, Bailey DJ, Coon JJ: Compass: A suite of pre-and post-search proteomics software tools for omssa. Proteomics 2011;11:1064-1074.
    • (2011) Proteomics , vol.11 , pp. 1064-1074
    • Wenger, C.D.1    Phanstiel, D.H.2    Lee, M.V.3    Bailey, D.J.4    Coon, J.J.5
  • 166
    • 43049127826 scopus 로고    scopus 로고
    • PeptideAtlas: A resource for target selection for emerging targeted proteomics workflows
    • DOI 10.1038/embor.2008.56, PII EMBOR200856
    • Deutsch EW, Lam H, Aebersold R: Peptideatlas: A resource for target selection for emerging targeted proteomics workflows. EMBO Rep 2008;9:429-434. (Pubitemid 351627279)
    • (2008) EMBO Reports , vol.9 , Issue.5 , pp. 429-434
    • Deutsch, E.W.1    Lam, H.2    Aebersold, R.3
  • 167
    • 11144320641 scopus 로고    scopus 로고
    • Open source system for analyzing, validating, and storing protein identification data
    • DOI 10.1021/pr049882h
    • Craig R Cortens JP Beavis RC Open source system for analyzing, validating, and storing protein identification data J Proteome Res 2004 3 1234-1242. (Pubitemid 40040378)
    • (2004) Journal of Proteome Research , vol.3 , Issue.6 , pp. 1234-1242
    • Craig, R.1    Cortens, J.P.2    Beavis, R.C.3
  • 168
    • 84857980282 scopus 로고    scopus 로고
    • Analysis of high accuracy quantitative proteomics data in the maxqb database
    • Schaab C, Geiger T, Stoehr G, Cox J, Mann M: Analysis of high accuracy, quantitative proteomics data in the maxqb database. Mol Cell Proteomics 2012;11:M111 014068.
    • (2012) Mol Cell Proteomics , vol.11 , pp. 111014068
    • Schaab, C.1    Geiger, T.2    Stoehr, G.3    Cox, J.4    Mann, M.5
  • 169
    • 61349182486 scopus 로고    scopus 로고
    • Recent developments in public proteomic ms repositories and pipelines
    • Mead JA, Bianco L, Bessant C: Recent developments in public proteomic ms repositories and pipelines. Proteomics 2009;9:861-881.
    • (2009) Proteomics , vol.9 , pp. 861-881
    • Mead, J.A.1    Bianco, L.2    Bessant, C.3
  • 171
    • 77449100000 scopus 로고    scopus 로고
    • Usingthe pride proteomics identifications database for knowledge discovery and data analysis
    • Jones P, Martens L: Usingthe pride proteomics identifications database for knowledge discovery and data analysis. Methods Mol Biol 2010;604:297-307.
    • (2010) Methods Mol Biol , vol.604 , pp. 297-307
    • Jones, P.1    Martens, L.2
  • 172
    • 58149157628 scopus 로고    scopus 로고
    • The pride proteomics identifications database: Data submission, query, and dataset comparison
    • Jones P, Cote R: The pride proteomics identifications database: Data submission, query, and dataset comparison. Methods Mol Biol 2008;484:287-303.
    • (2008) Methods Mol Biol , vol.484 , pp. 287-303
    • Jones, P.1    Cote, R.2
  • 179
    • 84871959637 scopus 로고    scopus 로고
    • Method ofthe year 2012
    • Method ofthe year 2012. Nat Meth 2013;10:1-1.
    • (2013) Nat Meth , vol.10 , pp. 1-1
  • 180
    • 84860861462 scopus 로고    scopus 로고
    • Targeted proteomics
    • Doerr A: Targeted proteomics. Nat Meth 2011;8:43-43.
    • (2011) Nat Meth , vol.8 , pp. 43-43
    • Doerr, A.1
  • 181
    • 84871958447 scopus 로고    scopus 로고
    • Mass sp ectrometry-based targeted proteomics
    • Doerr A: Mass sp ectrometry-based targeted proteomics. Nat Meth 2013;10:23-23
    • (2013) Nat Meth , vol.10 , pp. 23-23
    • Doerr, A.1
  • 182
    • 84861860481 scopus 로고    scopus 로고
    • Targeted data extraction of the ms/ms spe ctra generated by data-independent acquisition: A new conceptfor consistent and accurate proteome analysis
    • Gillet LC, Navarro P, Tate S, Rost H, Selevsek N, Reiter L, Bonner R, Aebersold R: Targeted data extraction of the ms/ms spe ctra generated by data-independent acquisition: A new conceptfor consistent and accurate proteome analysis. Mol Cell Proteom 2012;11:0111.016717.
    • (2012) Mol Cell Proteom , vol.11 , pp. 0111016717
    • Gillet, L.C.1    Navarro, P.2    Tate, S.3    Rost, H.4    Selevsek, N.5    Reiter, L.6    Bonner, R.7    Aebersold, R.8
  • 184
    • 84881486980 scopus 로고    scopus 로고
    • Mass spectrometric immunoassay and multiple reaction monitoring as targeted ms-based quantitative approaches in biomarker development: Potential applications to cardiovascular dise ase and diabetes
    • Yassine H, Borges CR, Schaab MR, Billheimer D, Stump C, Reaven P, Lau SS, Nelson R: Mass spectrometric immunoassay and multiple reaction monitoring as targeted ms-based quantitative approaches in biomarker development: Potential applications to cardiovascular dise ase and diabetes. Proteomics Clin Appl. 2013;7:528-540.
    • (2013) Proteomics Clin Appl. , vol.7 , pp. 528-540
    • Yassine, H.1    Borges, C.R.2    Schaab, M.R.3    Billheimer, D.4    Stump, C.5    Reaven, P.6    Lau, S.S.7    Nelson, R.8
  • 185
    • 84891675858 scopus 로고    scopus 로고
    • Rapid development of sensitive, high-throughput, quantitative and highly selective mass spectrometric targeted immunoassays for clinically important proteins in human plasma and serum
    • Krastins B, Prakash A, Sarracino DA, Nedelkov D, Niederkofler EE, Kiernan UA, Nelson R, Vogelsang MS, Vadali G, Garces A: Rapid development of sensitive, high-throughput, quantitative and highly selective mass spectrometric targeted immunoassays for clinically important proteins in human plasma and serum. Clin Biochem 2013;46:399-410.
    • (2013) Clin Biochem , vol.46 , pp. 399-410
    • Krastins, B.1    Prakash, A.2    Sarracino, D.A.3    Nedelkov, D.4    Niederkofler, E.E.5    Kiernan, U.A.6    Nelson, R.7    Vogelsang, M.S.8    Vadali, G.9    Garces, A.10
  • 187
    • 1842716662 scopus 로고    scopus 로고
    • 1 H NMR and multivariate analysis technique
    • DOI 10.1016/j.phytochem.2004.01.019, PII S0031942204000421
    • Ch oi HK, Choi YH, Verberne M, Lefeber AW, Erkelens C, Verpoorte R: Metabolic fingerprinting of wild type and transgenic tobacco plants by lh nmr and multivariate analysis technique. Phytochemistry 2004;65:857-86 4. (Pubitemid 38471762)
    • (2004) Phytochemistry , vol.65 , Issue.7 , pp. 857-864
    • Choi, H.-K.1    Choi, Y.H.2    Verberne, M.3    Lefeber, A.W.M.4    Erkelens, C.5    Verpoorte, R.6
  • 188
    • 1642312092 scopus 로고    scopus 로고
    • High-Throughput Metabolic Fingerprinting of Legume Silage Fermentations via Fourier Transform Infrared Spectroscopy and Chemometrics
    • DOI 10.1128/AEM.70.3.1583-1592.2004
    • Johnson HE, Broadhurst D, Kell DB, Theodorou MK, Merry RJ, Griffith GW: High-throughput metabolic fingerprinting of legume silage fermentations via fourier transform infrared spectroscopy and chemometrics. Ap pl Environ Microbiol 2004;70:1583-1592. (Pubitemid 38372074)
    • (2004) Applied and Environmental Microbiology , vol.70 , Issue.3 , pp. 1583-1592
    • Johnson, H.E.1    Broadhurst, D.2    Kell, D.B.3    Theodorou, M.K.4    Merry, R.J.5    Griffith, G.W.6
  • 189
    • 0038016968 scopus 로고    scopus 로고
    • Investigating plant-plant interference by metabolic fingerprinting
    • DOI 10.1016/S0031-9422(03)00288-7
    • Gidman E Goodacre R Emmett B Smith AR Gwynn-Jones D: Investigating plant-plant interference by metabolic fingerprinting. Phytochemistry2003 63; 705-710. (Pubitemid 36818553)
    • (2003) Phytochemistry , vol.63 , Issue.6 , pp. 705-710
    • Gidman, E.1    Goodacre, R.2    Emmett, B.3    Smith, A.R.4    Gwynn-Jones, D.5
  • 190
    • 0038699591 scopus 로고    scopus 로고
    • High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
    • DOI 10.1038/nbt823
    • Allen J, Davey HM, Broadhurst D, Heald JK, Rowland JJ, Oliver SG, Kell DB: High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. Nat Biotechnol 2003; 21:692-696. (Pubitemid 36638098)
    • (2003) Nature Biotechnology , vol.21 , Issue.6 , pp. 692-696
    • Allen, J.1    Davey, H.M.2    Broadhurst, D.3    Heald, J.K.4    Rowland, J.J.5    Oliver, S.G.6    Kell, D.B.7
  • 191
    • 49049103814 scopus 로고    scopus 로고
    • Utility of magnetic resonance imaging and nuclear magnetic resonance-based metabolomics for quantification of inflammatory lung injury
    • Serkova NJ, Van Rheen Z, Tobias M, Pitzer JE, Wilkinson JE, Stringer KA: Utility of magnetic resonance imaging and nuclear magnetic resonance-based metabolomics for quantification of inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol 2008;295:L152-161.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295 , pp. 152-161
    • Serkova, N.J.1    Van Rheen, Z.2    Tobias, M.3    Pitzer, J.E.4    Wilkinson, J.E.5    Stringer, K.A.6
  • 193
    • 0032168794 scopus 로고    scopus 로고
    • Systematic functional analysis of the yeast genome
    • DOI 10.1016/S0167-7799(98)01214-1, PII S0167779998012141
    • Oliver SG, W inson MK, Kell DB, Baganz F: Systematic functional analysis of the yeast genome. Trends Biotechnol 1998;16:373-378. (Pubitemid 28410425)
    • (1998) Trends in Biotechnology , vol.16 , Issue.9 , pp. 373-378
    • Oliver, S.G.1    Winson, M.K.2    Kell, D.B.3    Baganz, F.4
  • 194
    • 0032694577 scopus 로고    scopus 로고
    • Metabonomics Understandingthe meta bolic responses ofliving systems to pathophysiological stimuli via multivariate statistical analysis of biological nmr spectroscopic data
    • Nicholson JK, Lindon JC, Holmes E: ' Metabonomics': Understandingthe meta bolic responses ofliving systems to pathophysiological stimuli via multivariate statistical analysis of biological nmr spectroscopic data. Xenobiotica 1999;29:1181-1189.
    • (1999) Xenobiotica , vol.29 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 195
    • 84881089210 scopus 로고    scopus 로고
    • Exploratory investigation of plasma metabolomics in human lung adenocarcinoma
    • Wen T, Gao L, Wen Z, Wu C, Tan CS, Toh WZ, Ong CN: Exploratory investigation of plasma metabolomics in human lung adenocarcinoma. Mol BioS yst2013;9:2370-2378.
    • (2013) Mol Bio Syst , vol.9 , pp. 2370-2378
    • Wen, T.1    Gao, L.2    Wen, Z.3    Wu, C.4    Tan, C.S.5    Toh, W.Z.6    Ong, C.N.7
  • 196
    • 0142040405 scopus 로고    scopus 로고
    • Metabolomics in systems biology
    • Weckwerth W: Metabolomics in systems biology. Annu Rev Plant Biol 2003;54:669-689. (Pubitemid 37400009)
    • (2003) Annual Review of Plant Biology , vol.54 , pp. 669-689
    • Weckwerth, W.1
  • 200
    • 84888371490 scopus 로고    scopus 로고
    • Method development and validation for rat serum fingerprinting with ce-ms: Applicationto ventilator-induced-lung-injury study
    • Naz S, Garcia A, Rusak M, Barbas C: Method development and validation for rat serum fingerprinting with ce-ms: Applicationto ventilator-induced-lung- injury study. Anal Bioanal Chem 2013;405:4849-4858.
    • (2013) Anal Bioanal Chem , vol.405 , pp. 4849-4858
    • Naz, S.1    Garcia, A.2    Rusak, M.3    Barbas, C.4
  • 201
    • 84884413414 scopus 로고    scopus 로고
    • Nmr-based metabolomics in human disease diagnosis: Applications, limitations, and recommendations
    • Emwas A-H, Salek R, Griffin J, MerzabanJ: Nmr-based metabolomics in human disease diagnosis: Applications, limitations, and recommendations. Metabolomics 2013;9:1048-1072.
    • (2013) Metabolomics , vol.9 , pp. 1048-1072
    • Emwas, A.-H.1    Salek, R.2    Griffin, J.3    Merzaban, J.4
  • 205
    • 84879402480 scopus 로고    scopus 로고
    • Integration of cancer gene co-expression network and metabolic networkto uncoverpotential cancer drugtargets
    • Chen J, Ma M, Sh en N, Xi JJ, Tian W: Integration of cancer gene co-expression network and metabolic networkto uncoverpotential cancer drugtargets. J Proteome Res 2013;12:2354-2364.
    • (2013) J Proteome Res , vol.12 , pp. 2354-2364
    • Chen, J.1    Ma, M.2    Shen, N.3    Xi, J.J.4    Tian, W.5
  • 206
    • 85014049276 scopus 로고    scopus 로고
    • Bioinform atics approaches to integrate metabolomics and other systems biology data
    • in Saito K, Dixon R, Willmitzer L (edsj Springer Berlin Heidelberg
    • Mehrotra B, Mendes P: Bioinform atics approaches to integrate metabolomics and other systems biology data; in Saito K, Dixon R, Willmitzer L (edsj: Plant metabolomics. Springer Berlin Heidelberg, 2006, vol 57, pp 105-115.
    • (2006) Plant Metabolomics. , vol.57 , pp. 105-115
    • Mehrotra, B.1    Mendes, P.2
  • 207
    • 33748468414 scopus 로고    scopus 로고
    • Meta bolomics technology and bioinformatics
    • ShulaevV: Metabolomicstechnologya ndbioinformatics. BriefBioinformat2006; 7:128-139.
    • (2006) Brief Bioinformat , vol.7 , pp. 128-139
    • Shulaev, V.1
  • 208
    • 0033452842 scopus 로고    scopus 로고
    • An integrated method for spectrum extraction and compound identification from gas chromatography/mass spectrometry data
    • DOI 10.1016/S1044-0305(99)00047-1, PII S1044030599000471
    • Stein SE: An integrated method for spectrum extraction and compound identification from gas chromatography/mass spectrometry data. J Am Soc Mass Spectrom 1999;10:770-781. (Pubitemid 34506228)
    • (1999) Journal of the American Society for Mass Spectrometry , vol.10 , Issue.8 , pp. 770-781
    • Stein, S.E.1
  • 209
    • 77954772536 scopus 로고    scopus 로고
    • Mzmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
    • Pluskal T, Castillo S, Villar-Briones A, Oresic M: Mzmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data. BMC Bioinformatics 2010; 11:395.
    • (2010) BMC Bioinformatics , vol.11 , pp. 395
    • Pluskal, T.1    Castillo, S.2    Villar-Briones, A.3    Oresic, M.4
  • 210
    • 56649102388 scopus 로고    scopus 로고
    • MeltDB: A software platform for the analysis and integration of metabolomics experiment data
    • DOI 10.1093/bioinformatics/btn452
    • Neuweger H Albaum SP Dondrup M Persicke M Watt T Niehaus K Stoye J GoesmannA: Meltdb: A software platform forthe analysis and integration of metabolomics experiment data Bioinfor matics 2008 24 2726-2732. (Pubitemid 352722615)
    • (2008) Bioinformatics , vol.24 , Issue.23 , pp. 2726-2732
    • Neuweger, H.1    Albaum, S.P.2    Dondrup, M.3    Persicke, M.4    Watt, T.5    Niehaus, K.6    Stoye, J.7    Goesmann, A.8
  • 212
    • 32444446805 scopus 로고    scopus 로고
    • XCMS: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification
    • DOI 10.1021/ac051437y
    • Smith CA, Want EJ, O'Maille G, Abagyan R, Siuzdak G: Xcms: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal Chem 2006;78:779-787 . (Pubitemid 43228585)
    • (2006) Analytical Chemistry , vol.78 , Issue.3 , pp. 779-787
    • Smith, C.A.1    Want, E.J.2    O'Maille, G.3    Abagyan, R.4    Siuzdak, G.5
  • 216
    • 84890050726 scopus 로고    scopus 로고
    • Systems biology and p4 medicine: Past, present, and future
    • Hood L: Systems biology and p4 medicine: Past, present, and future. Rambam Maimonides Med J 2013;4:e0012.
    • (2013) Rambam Maimonides Med J , vol.4
    • Hood, L.1


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