메뉴 건너뛰기




Volumn 3 JUN, Issue , 2013, Pages

Epigenetic therapy in lung cancer - Role of microRNAs

Author keywords

Biomarker; Diagnosis; Lung cancer; microRNA; Prognosis; Therapy

Indexed keywords

CISPLATIN; DNA METHYLTRANSFERASE 3A; MICRORNA; MICRORNA 101; MICRORNA 106A; MICRORNA 107; MICRORNA 124A; MICRORNA 126; MICRORNA 145; MICRORNA 17; MICRORNA 182; MICRORNA 185; MICRORNA 18A; MICRORNA 192; MICRORNA 19A; MICRORNA 19B 1; MICRORNA 203; MICRORNA 20A; MICRORNA 21; MICRORNA 210; MICRORNA 212; MICRORNA 29; MICRORNA 29A; MICRORNA 29B; MICRORNA 29C; MICRORNA 30A; MICRORNA 31; MICRORNA 519C; MICRORNA 92A 1; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84885730364     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2013.00158     Document Type: Review
Times cited : (26)

References (93)
  • 1
    • 79961108629 scopus 로고    scopus 로고
    • Reduced lung-cancer mortality with low-dose computed tomographic screening
    • doi:10.1056/NEJMoa1102873
    • Aberle, D. R., Adams, A. M., Berg, C. D., Black, W. C., Clapp, J. D., Fagerstrom, R. M., et al. (2011a). Reduced lung-cancer mortality with low-dose computed tomographic screening. N. Engl. J. Med. 365, 395-409. doi:10.1056/NEJMoa1102873.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 395-409
    • Aberle, D.R.1    Adams, A.M.2    Berg, C.D.3    Black, W.C.4    Clapp, J.D.5    Fagerstrom, R.M.6
  • 2
    • 84863229324 scopus 로고    scopus 로고
    • The National Lung Screening Trial: overview and study design
    • doi:10.1148/radiol.10091808
    • Aberle, D. R., Berg, C. D., Black, W. C., Church, T. R., Fagerstrom, R. M., Galen, B. I., et al. (2011b). The National Lung Screening Trial: overview and study design. Radiology 258, 243-253. doi:10.1148/radiol.10091808.
    • (2011) Radiology , vol.258 , pp. 243-253
    • Aberle, D.R.1    Berg, C.D.2    Black, W.C.3    Church, T.R.4    Fagerstrom, R.M.5    Galen, B.I.6
  • 3
    • 80053005207 scopus 로고    scopus 로고
    • MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration
    • doi:10.1002/ijc.25939
    • Arora, S., Ranade, A. R., Tran, N. L., Nasser, S., Sridhar, S., Korn, R. L., et al. (2011). MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration. Int. J. Cancer 129, 2621-2631. doi:10.1002/ijc.25939.
    • (2011) Int. J. Cancer , vol.129 , pp. 2621-2631
    • Arora, S.1    Ranade, A.R.2    Tran, N.L.3    Nasser, S.4    Sridhar, S.5    Korn, R.L.6
  • 4
    • 0346238665 scopus 로고    scopus 로고
    • Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
    • doi:10.1056/NEJMoa031644
    • Arriagada, R., Bergman, B., Dunant, A., Le Chevalier, T., Pignon, J. P., and Vansteenkiste, J. (2004). Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N. Engl. J. Med. 350, 351-360. doi:10.1056/NEJMoa031644.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 351-360
    • Arriagada, R.1    Bergman, B.2    Dunant, A.3    Le Chevalier, T.4    Pignon, J.P.5    Vansteenkiste, J.6
  • 5
    • 79958759916 scopus 로고    scopus 로고
    • Reducing the risk of overdiagnosis in lung cancer: a support from molecular biology
    • doi:10.1002/jcp.22558
    • Barba, M., Felsani, A., Rinaldi, M., Giunta, S., Malorni, W., and Paggi, M. G. (2011). Reducing the risk of overdiagnosis in lung cancer: a support from molecular biology. J. Cell. Physiol. 226, 2213-2214. doi:10.1002/jcp.22558.
    • (2011) J. Cell. Physiol. , vol.226 , pp. 2213-2214
    • Barba, M.1    Felsani, A.2    Rinaldi, M.3    Giunta, S.4    Malorni, W.5    Paggi, M.G.6
  • 6
    • 77954316346 scopus 로고    scopus 로고
    • MicroRNA expression differentiates between primary lung tumors and metastases to the lung
    • doi:10.1016/j.prp.2010.03.005
    • Barshack, I., Lithwick-Yanai, G., Afek, A., Rosenblatt, K., Tabibian-Keissar, H., Zepeniuk, M., et al. (2010). MicroRNA expression differentiates between primary lung tumors and metastases to the lung. Pathol. Res. Pract. 206, 578-584. doi:10.1016/j.prp.2010.03.005.
    • (2010) Pathol. Res. Pract. , vol.206 , pp. 578-584
    • Barshack, I.1    Lithwick-Yanai, G.2    Afek, A.3    Rosenblatt, K.4    Tabibian-Keissar, H.5    Zepeniuk, M.6
  • 7
    • 84866761999 scopus 로고    scopus 로고
    • Developments in the treatment of early NSCLC: when to use chemotherapy
    • doi:10.1093/annonc/mds347
    • Besse, B., and Le Chevalier, T. (2012). Developments in the treatment of early NSCLC: when to use chemotherapy. Ann. Oncol. 23(Suppl. 10), x52-x59. doi:10.1093/annonc/mds347.
    • (2012) Ann. Oncol. , vol.23 , Issue.SUPPL. 10
    • Besse, B.1    Le Chevalier, T.2
  • 8
    • 79952539094 scopus 로고    scopus 로고
    • Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549)
    • doi:10.1186/1756-9966-30-20
    • Bian, H. B., Pan, X., Yang, J. S., Wang, Z. X., and De, W. (2011). Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549). J. Exp. Clin. Cancer Res. 30, 20. doi:10.1186/1756-9966-30-20.
    • (2011) J. Exp. Clin. Cancer Res. , vol.30 , pp. 20
    • Bian, H.B.1    Pan, X.2    Yang, J.S.3    Wang, Z.X.4    De, W.5
  • 9
    • 84977478146 scopus 로고    scopus 로고
    • MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer
    • doi:10.1073/pnas.1100048108
    • Boeri, M., Verri, C., Conte, D., Roz, L., Modena, P., Facchinetti, F., et al. (2011). MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer. Proc. Natl. Acad. Sci. U.S.A. 108, 3713-3718. doi:10.1073/pnas.1100048108.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 3713-3718
    • Boeri, M.1    Verri, C.2    Conte, D.3    Roz, L.4    Modena, P.5    Facchinetti, F.6
  • 10
    • 78649760112 scopus 로고    scopus 로고
    • Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma
    • doi:10.1016/S0305-7372(10)70016-5
    • Bronte, G., Rizzo, S., La Paglia, L., Adamo, V., Siragusa, S., Ficorella, C., et al. (2010). Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma. Cancer Treat. Rev. 36(Suppl. 3), S21-S29. doi:10.1016/S0305-7372(10)70016-5.
    • (2010) Cancer Treat. Rev. , vol.36 , Issue.SUPPL. 3
    • Bronte, G.1    Rizzo, S.2    La Paglia, L.3    Adamo, V.4    Siragusa, S.5    Ficorella, C.6
  • 11
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • doi:10.1073/pnas.242606799
    • Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., et al. (2002). Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 99, 15524-15529. doi:10.1073/pnas.242606799.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5    Noch, E.6
  • 12
    • 27244434788 scopus 로고    scopus 로고
    • A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • doi:10.1056/NEJMoa050995
    • Calin, G. A., Ferracin, M., Cimmino, A., Di Leva, G., Shimizu, M., Wojcik, S. E., et al. (2005). A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N. Engl. J. Med. 353, 1793-1801. doi:10.1056/NEJMoa050995.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3    Di Leva, G.4    Shimizu, M.5    Wojcik, S.E.6
  • 13
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • doi:10.1073/pnas.0307323101
    • Calin, G. A., Sevignani, C., Dumitru, C. D., Hyslop, T., Noch, E., Yendamuri, S., et al. (2004). Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. U.S.A. 101, 2999-3004. doi:10.1073/pnas.0307323101.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3    Hyslop, T.4    Noch, E.5    Yendamuri, S.6
  • 14
    • 34548814135 scopus 로고    scopus 로고
    • MicroRNAs and cell cycle regulation
    • doi:10.4161/cc.6.17.4641
    • Carleton, M., Cleary, M. A., and Linsley, P. S. (2007). MicroRNAs and cell cycle regulation. Cell Cycle 6, 2127-2132. doi:10.4161/cc.6.17.4641.
    • (2007) Cell Cycle , vol.6 , pp. 2127-2132
    • Carleton, M.1    Cleary, M.A.2    Linsley, P.S.3
  • 15
    • 77950799838 scopus 로고    scopus 로고
    • MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis
    • doi:10.1158/0008-5472.CAN-09-2448
    • Cha, S. T., Chen, P. S., Johansson, G., Chu, C. Y., Wang, M. Y., Jeng, Y. M., et al. (2010). MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis. Cancer Res. 70, 2675-2685. doi:10.1158/0008-5472.CAN-09-2448.
    • (2010) Cancer Res. , vol.70 , pp. 2675-2685
    • Cha, S.T.1    Chen, P.S.2    Johansson, G.3    Chu, C.Y.4    Wang, M.Y.5    Jeng, Y.M.6
  • 16
    • 53349177819 scopus 로고    scopus 로고
    • Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
    • doi:10.1038/cr.2008.282
    • Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., et al. (2008). Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 18, 997-1006. doi:10.1038/cr.2008.282.
    • (2008) Cell Res. , vol.18 , pp. 997-1006
    • Chen, X.1    Ba, Y.2    Ma, L.3    Cai, X.4    Yin, Y.5    Wang, K.6
  • 17
    • 14844364472 scopus 로고    scopus 로고
    • Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
    • doi:10.1093/nar/gki200
    • Cheng, A. M., Byrom, M. W., Shelton, J., and Ford, L. P. (2005). Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res. 33, 1290-1297. doi:10.1093/nar/gki200.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 1290-1297
    • Cheng, A.M.1    Byrom, M.W.2    Shelton, J.3    Ford, L.P.4
  • 18
    • 54249117763 scopus 로고    scopus 로고
    • A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk
    • doi:10.1158/0008-5472.CAN-08-2129
    • Chin, L. J., Ratner, E., Leng, S., Zhai, R., Nallur, S., Babar, I., et al. (2008). A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res. 68, 8535-8540. doi:10.1158/0008-5472.CAN-08-2129.
    • (2008) Cancer Res. , vol.68 , pp. 8535-8540
    • Chin, L.J.1    Ratner, E.2    Leng, S.3    Zhai, R.4    Nallur, S.5    Babar, I.6
  • 19
    • 52949129831 scopus 로고    scopus 로고
    • Circular reasoning: microRNAs and cell-cycle control
    • doi:10.1016/j.tibs.2008.06.008
    • Chivukula, R. R., and Mendell, J. T. (2008). Circular reasoning: microRNAs and cell-cycle control. Trends Biochem. Sci. 33, 474-481. doi:10.1016/j.tibs.2008.06.008.
    • (2008) Trends Biochem. Sci. , vol.33 , pp. 474-481
    • Chivukula, R.R.1    Mendell, J.T.2
  • 20
    • 67650365554 scopus 로고    scopus 로고
    • Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation
    • doi:10.1016/j.ejca.2009.04.039
    • Cho, W. C., Chow, A. S., and Au, J. S. (2009). Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation. Eur. J. Cancer 45, 2197-2206. doi:10.1016/j.ejca.2009.04.039.
    • (2009) Eur. J. Cancer , vol.45 , pp. 2197-2206
    • Cho, W.C.1    Chow, A.S.2    Au, J.S.3
  • 21
    • 78650976540 scopus 로고    scopus 로고
    • Prognostic impact of MiR-155 in non-small cell lung cancer evaluated by in situ hybridization
    • doi:10.1186/1479-5876-9-6
    • Donnem, T., Eklo, K., Berg, T., Sorbye, S. W., Lonvik, K., Al-Saad, S., et al. (2011). Prognostic impact of MiR-155 in non-small cell lung cancer evaluated by in situ hybridization. J. Transl. Med. 9, 6. doi:10.1186/1479-5876-9-6.
    • (2011) J. Transl. Med. , vol.9 , pp. 6
    • Donnem, T.1    Eklo, K.2    Berg, T.3    Sorbye, S.W.4    Lonvik, K.5    Al-Saad, S.6
  • 22
    • 69449105719 scopus 로고    scopus 로고
    • miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1
    • doi:10.1158/1541-7786.MCR-08-0507
    • Du, L., Schageman, J. J., Subauste, M. C., Saber, B., Hammond, S. M., Prudkin, L., et al. (2009). miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1. Mol. Cancer Res. 7, 1234-1243. doi:10.1158/1541-7786.MCR-08-0507.
    • (2009) Mol. Cancer Res. , vol.7 , pp. 1234-1243
    • Du, L.1    Schageman, J.J.2    Subauste, M.C.3    Saber, B.4    Hammond, S.M.5    Prudkin, L.6
  • 23
    • 35649020283 scopus 로고    scopus 로고
    • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
    • doi:10.1073/pnas.0707628104
    • Fabbri, M., Garzon, R., Cimmino, A., Liu, Z., Zanesi, N., Callegari, E., et al. (2007). MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc. Natl. Acad. Sci. U.S.A. 104, 15805-15810. doi:10.1073/pnas.0707628104.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 15805-15810
    • Fabbri, M.1    Garzon, R.2    Cimmino, A.3    Liu, Z.4    Zanesi, N.5    Callegari, E.6
  • 24
    • 84864503916 scopus 로고    scopus 로고
    • MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
    • doi:10.1073/pnas.1209414109
    • Fabbri, M., Paone, A., Calore, F., Galli, R., Gaudio, E., Santhanam, R., et al. (2012). MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response. Proc. Natl. Acad. Sci. U.S.A. 109, E2110-E2116. doi:10.1073/pnas.1209414109.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109
    • Fabbri, M.1    Paone, A.2    Calore, F.3    Galli, R.4    Gaudio, E.5    Santhanam, R.6
  • 25
    • 80055080741 scopus 로고    scopus 로고
    • MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells
    • doi:10.1093/nar/gkr232
    • Feng, S., Cong, S., Zhang, X., Bao, X., Wang, W., Li, H., et al. (2011). MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells. Nucleic Acids Res. 39, 6669-6678. doi:10.1093/nar/gkr232.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 6669-6678
    • Feng, S.1    Cong, S.2    Zhang, X.3    Bao, X.4    Wang, W.5    Li, H.6
  • 26
    • 76049128595 scopus 로고    scopus 로고
    • Estimates of cancer incidence and mortality in Europe in 2008
    • doi:10.1016/j.ejca.2009.12.014
    • Ferlay, J., Parkin, D. M., and Steliarova-Foucher, E. (2010). Estimates of cancer incidence and mortality in Europe in 2008. Eur. J. Cancer 46, 765-781. doi:10.1016/j.ejca.2009.12.014.
    • (2010) Eur. J. Cancer , vol.46 , pp. 765-781
    • Ferlay, J.1    Parkin, D.M.2    Steliarova-Foucher, E.3
  • 27
    • 70849087385 scopus 로고    scopus 로고
    • miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer
    • doi:10.1093/carcin/bgp219
    • Gallardo, E., Navarro, A., Vinolas, N., Marrades, R. M., Diaz, T., Gel, B., et al. (2009). miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer. Carcinogenesis 30, 1903-1909. doi:10.1093/carcin/bgp219.
    • (2009) Carcinogenesis , vol.30 , pp. 1903-1909
    • Gallardo, E.1    Navarro, A.2    Vinolas, N.3    Marrades, R.M.4    Diaz, T.5    Gel, B.6
  • 28
    • 77950203807 scopus 로고    scopus 로고
    • miR-181a and miR-630 regulate cisplatin-induced cancer cell death
    • doi:10.1158/0008-5472.CAN-09-3112
    • Galluzzi, L., Morselli, E., Vitale, I., Kepp, O., Senovilla, L., Criollo, A., et al. (2010). miR-181a and miR-630 regulate cisplatin-induced cancer cell death. Cancer Res. 70, 1793-1803. doi:10.1158/0008-5472.CAN-09-3112.
    • (2010) Cancer Res. , vol.70 , pp. 1793-1803
    • Galluzzi, L.1    Morselli, E.2    Vitale, I.3    Kepp, O.4    Senovilla, L.5    Criollo, A.6
  • 29
    • 77954315239 scopus 로고    scopus 로고
    • Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis
    • doi:10.1016/j.biopha.2010.01.018
    • Gao, W., Yu, Y., Cao, H., Shen, H., Li, X., Pan, S., et al. (2010). Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis. Biomed. Pharmacother. 64, 399-408. doi:10.1016/j.biopha.2010.01.018.
    • (2010) Biomed. Pharmacother. , vol.64 , pp. 399-408
    • Gao, W.1    Yu, Y.2    Cao, H.3    Shen, H.4    Li, X.5    Pan, S.6
  • 30
    • 77952965634 scopus 로고    scopus 로고
    • ALK, lung cancer, and personalized therapy: portent of the future?
    • doi:10.1093/jnci/djq184
    • Garber, K. (2010). ALK, lung cancer, and personalized therapy: portent of the future? J. Natl. Cancer Inst. 102, 672-675. doi:10.1093/jnci/djq184.
    • (2010) J. Natl. Cancer Inst. , vol.102 , pp. 672-675
    • Garber, K.1
  • 31
    • 70949104622 scopus 로고    scopus 로고
    • miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation
    • Garofalo, M., Di Leva, G., Romano, G., Nuovo, G., Suh, S. S., Ngankeu, A., et al. (2009). miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. Cancer Cell 16, 498-509.
    • (2009) Cancer Cell , vol.16 , pp. 498-509
    • Garofalo, M.1    Di Leva, G.2    Romano, G.3    Nuovo, G.4    Suh, S.S.5    Ngankeu, A.6
  • 32
    • 42749093490 scopus 로고    scopus 로고
    • MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer
    • doi:10.1038/onc.2008.6
    • Garofalo, M., Quintavalle, C., Di Leva, G., Zanca, C., Romano, G., Taccioli, C., et al. (2008). MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer. Oncogene 27, 3845-3855. doi:10.1038/onc.2008.6.
    • (2008) Oncogene , vol.27 , pp. 3845-3855
    • Garofalo, M.1    Quintavalle, C.2    Di Leva, G.3    Zanca, C.4    Romano, G.5    Taccioli, C.6
  • 33
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • doi:10.1158/0008-5472.CAN-05-2352
    • Hayashita, Y., Osada, H., Tatematsu, Y., Yamada, H., Yanagisawa, K., Tomida, S., et al. (2005). A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 65, 9628-9632. doi:10.1158/0008-5472.CAN-05-2352.
    • (2005) Cancer Res. , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3    Yamada, H.4    Yanagisawa, K.5    Tomida, S.6
  • 34
    • 77950498821 scopus 로고    scopus 로고
    • Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer
    • doi:10.1200/JCO.2009.24.9342
    • Hu, Z., Chen, X., Zhao, Y., Tian, T., Jin, G., Shu, Y., et al. (2010). Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J. Clin. Oncol. 28, 1721-1726. doi:10.1200/JCO.2009.24.9342.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 1721-1726
    • Hu, Z.1    Chen, X.2    Zhao, Y.3    Tian, T.4    Jin, G.5    Shu, Y.6
  • 35
    • 77951716642 scopus 로고    scopus 로고
    • miR-212 increases tumor necrosis factor-related apoptosis-inducing ligand sensitivity in non-small cell lung cancer by targeting the antiapoptotic protein PED
    • doi:10.1158/0008-5472.CAN-09-3341
    • Incoronato, M., Garofalo, M., Urso, L., Romano, G., Quintavalle, C., Zanca, C., et al. (2010). miR-212 increases tumor necrosis factor-related apoptosis-inducing ligand sensitivity in non-small cell lung cancer by targeting the antiapoptotic protein PED. Cancer Res. 70, 3638-3646. doi:10.1158/0008-5472.CAN-09-3341.
    • (2010) Cancer Res. , vol.70 , pp. 3638-3646
    • Incoronato, M.1    Garofalo, M.2    Urso, L.3    Romano, G.4    Quintavalle, C.5    Zanca, C.6
  • 36
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • doi:10.1158/0008-5472.CAN-05-1783
    • Iorio, M. V., Ferracin, M., Liu, C. G., Veronese, A., Spizzo, R., Sabbioni, S., et al. (2005). MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 65, 7065-7070. doi:10.1158/0008-5472.CAN-05-1783.
    • (2005) Cancer Res. , vol.65 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3    Veronese, A.4    Spizzo, R.5    Sabbioni, S.6
  • 37
    • 61449208911 scopus 로고    scopus 로고
    • Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke
    • doi:10.1096/fj.08-121384
    • Izzotti, A., Calin, G. A., Arrigo, P., Steele, V. E., Croce, C. M., and De Flora, S. (2009). Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J. 23, 806-812. doi:10.1096/fj.08-121384.
    • (2009) FASEB J. , vol.23 , pp. 806-812
    • Izzotti, A.1    Calin, G.A.2    Arrigo, P.3    Steele, V.E.4    Croce, C.M.5    De Flora, S.6
  • 38
    • 79960042770 scopus 로고    scopus 로고
    • Targeted therapy in non-small-cell lung cancer-is it becoming a reality?
    • doi:10.1038/nrclinonc.2010.64
    • Janku, F., Stewart, D. J., and Kurzrock, R. (2010). Targeted therapy in non-small-cell lung cancer-is it becoming a reality? Nat. Rev. Clin. Oncol. 7, 401-414. doi:10.1038/nrclinonc.2010.64.
    • (2010) Nat. Rev. Clin. Oncol. , vol.7 , pp. 401-414
    • Janku, F.1    Stewart, D.J.2    Kurzrock, R.3
  • 39
    • 34548012848 scopus 로고    scopus 로고
    • The let-7 microRNA represses cell proliferation pathways in human cells
    • doi:10.1158/0008-5472.CAN-07-1083
    • Johnson, C. D., Esquela-Kerscher, A., Stefani, G., Byrom, M., Kelnar, K., Ovcharenko, D., et al. (2007). The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 67, 7713-7722. doi:10.1158/0008-5472.CAN-07-1083.
    • (2007) Cancer Res. , vol.67 , pp. 7713-7722
    • Johnson, C.D.1    Esquela-Kerscher, A.2    Stefani, G.3    Byrom, M.4    Kelnar, K.5    Ovcharenko, D.6
  • 40
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • doi:10.1016/j.cell.2005.01.014
    • Johnson, S. M., Grosshans, H., Shingara, J., Byrom, M., Jarvis, R., Cheng, A., et al. (2005). RAS is regulated by the let-7 microRNA family. Cell 120, 635-647. doi:10.1016/j.cell.2005.01.014.
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3    Byrom, M.4    Jarvis, R.5    Cheng, A.6
  • 41
    • 41649114199 scopus 로고    scopus 로고
    • Suppression of non-small cell lung tumor development by the let-7 microRNA family
    • doi:10.1073/pnas.0712321105
    • Kumar, M. S., Erkeland, S. J., Pester, R. E., Chen, C. Y., Ebert, M. S., Sharp, P. A., et al. (2008). Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc. Natl. Acad. Sci. U.S.A. 105, 3903-3908. doi:10.1073/pnas.0712321105.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 3903-3908
    • Kumar, M.S.1    Erkeland, S.J.2    Pester, R.E.3    Chen, C.Y.4    Ebert, M.S.5    Sharp, P.A.6
  • 42
    • 74549121893 scopus 로고    scopus 로고
    • MicroRNA expression differentiates histology and predicts survival of lung cancer
    • doi:10.1158/1078-0432.CCR-09-1736
    • Landi, M. T., Zhao, Y., Rotunno, M., Koshiol, J., Liu, H., Bergen, A. W., et al. (2010). MicroRNA expression differentiates histology and predicts survival of lung cancer. Clin. Cancer Res. 16, 430-441. doi:10.1158/1078-0432.CCR-09-1736.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 430-441
    • Landi, M.T.1    Zhao, Y.2    Rotunno, M.3    Koshiol, J.4    Liu, H.5    Bergen, A.W.6
  • 43
    • 65349166324 scopus 로고    scopus 로고
    • Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma
    • doi:10.1200/JCO.2008.19.4134
    • Lebanony, D., Benjamin, H., Gilad, S., Ezagouri, M., Dov, A., Ashkenazi, K., et al. (2009). Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma. J. Clin. Oncol. 27, 2030-2037. doi:10.1200/JCO.2008.19.4134.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 2030-2037
    • Lebanony, D.1    Benjamin, H.2    Gilad, S.3    Ezagouri, M.4    Dov, A.5    Ashkenazi, K.6
  • 44
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • doi:10.1101/gad.1540407
    • Lee, Y. S., and Dutta, A. (2007). The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev. 21, 1025-1030. doi:10.1101/gad.1540407.
    • (2007) Genes Dev. , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 45
    • 84860466755 scopus 로고    scopus 로고
    • MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer
    • doi:10.1093/carcin/bgs100
    • Lu, Y., Govindan, R., Wang, L., Liu, P. Y., Goodgame, B., Wen, W., et al. (2012). MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. Carcinogenesis 33, 1046-1054. doi:10.1093/carcin/bgs100.
    • (2012) Carcinogenesis , vol.33 , pp. 1046-1054
    • Lu, Y.1    Govindan, R.2    Wang, L.3    Liu, P.Y.4    Goodgame, B.5    Wen, W.6
  • 46
    • 34748900267 scopus 로고    scopus 로고
    • Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells
    • doi:10.1016/j.ydbio.2007.08.007
    • Lu, Y., Thomson, J. M., Wong, H. Y., Hammond, S. M., and Hogan, B. L. (2007). Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev. Biol. 310, 442-453. doi:10.1016/j.ydbio.2007.08.007.
    • (2007) Dev. Biol. , vol.310 , pp. 442-453
    • Lu, Y.1    Thomson, J.M.2    Wong, H.Y.3    Hammond, S.M.4    Hogan, B.L.5
  • 47
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • doi:10.1056/NEJMoa040938
    • Lynch, T. J., Bell, D. W., Sordella, R., Gurubhagavatula, S., Okimoto, R. A., Brannigan, B. W., et al. (2004). Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 350, 2129-2139. doi:10.1056/NEJMoa040938.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5    Brannigan, B.W.6
  • 48
    • 34447101200 scopus 로고    scopus 로고
    • Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92
    • doi:10.1038/sj.onc.1210425
    • Matsubara, H., Takeuchi, T., Nishikawa, E., Yanagisawa, K., Hayashita, Y., Ebi, H., et al. (2007). Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92. Oncogene 26, 6099-6105. doi:10.1038/sj.onc.1210425.
    • (2007) Oncogene , vol.26 , pp. 6099-6105
    • Matsubara, H.1    Takeuchi, T.2    Nishikawa, E.3    Yanagisawa, K.4    Hayashita, Y.5    Ebi, H.6
  • 49
    • 34548687035 scopus 로고    scopus 로고
    • Mir-29 regulates Mcl-1 protein expression and apoptosis
    • doi:10.1038/sj.onc.1210436
    • Mott, J. L., Kobayashi, S., Bronk, S. F., and Gores, G. J. (2007). Mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 26, 6133-6140. doi:10.1038/sj.onc.1210436.
    • (2007) Oncogene , vol.26 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 50
    • 70350596499 scopus 로고    scopus 로고
    • MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines
    • doi:10.1016/j.ejca.2009.09.014
    • Muniyappa, M. K., Dowling, P., Henry, M., Meleady, P., Doolan, P., Gammell, P., et al. (2009). MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. Eur. J. Cancer 45, 3104-3118. doi:10.1016/j.ejca.2009.09.014.
    • (2009) Eur. J. Cancer , vol.45 , pp. 3104-3118
    • Muniyappa, M.K.1    Dowling, P.2    Henry, M.3    Meleady, P.4    Doolan, P.5    Gammell, P.6
  • 51
    • 34547480764 scopus 로고    scopus 로고
    • Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing
    • doi:10.1073/pnas.0704559104
    • Nakamura, T., Canaani, E., and Croce, C. M. (2007). Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing. Proc. Natl. Acad. Sci. U.S.A. 104, 10980-10985. doi:10.1073/pnas.0704559104.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 10980-10985
    • Nakamura, T.1    Canaani, E.2    Croce, C.M.3
  • 52
    • 59649105246 scopus 로고    scopus 로고
    • MicroRNAs expressed during lung cancer development are expressed in human pseudoglandular lung embryogenesis
    • doi:10.1159/000201569
    • Navarro, A., Marrades, R. M., Vinolas, N., Quera, A., Agusti, C., Huerta, A., et al. (2009). MicroRNAs expressed during lung cancer development are expressed in human pseudoglandular lung embryogenesis. Oncology 76, 162-169. doi:10.1159/000201569.
    • (2009) Oncology , vol.76 , pp. 162-169
    • Navarro, A.1    Marrades, R.M.2    Vinolas, N.3    Quera, A.4    Agusti, C.5    Huerta, A.6
  • 53
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
    • doi:10.1126/science.1099314
    • Paez, J. G., Janne, P. A., Lee, J. C., Tracy, S., Greulich, H., Gabriel, S., et al. (2004). EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304, 1497-1500. doi:10.1126/science.1099314.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5    Gabriel, S.6
  • 54
    • 79251490374 scopus 로고    scopus 로고
    • New driver mutations in non-small-cell lung cancer
    • doi:10.1016/S1470-2045(10)70087-5
    • Pao, W., and Girard, N. (2011). New driver mutations in non-small-cell lung cancer. Lancet Oncol. 12, 175-180. doi:10.1016/S1470-2045(10)70087-5.
    • (2011) Lancet Oncol. , vol.12 , pp. 175-180
    • Pao, W.1    Girard, N.2
  • 55
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • doi:10.1073/pnas.0405220101
    • Pao, W., Miller, V., Zakowski, M., Doherty, J., Politi, K., Sarkaria, I., et al. (2004). EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc. Natl. Acad. Sci. U.S.A. 101, 13306-13311. doi:10.1073/pnas.0405220101.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3    Doherty, J.4    Politi, K.5    Sarkaria, I.6
  • 56
    • 75149130928 scopus 로고    scopus 로고
    • Evaluation of microRNA expression profiles that may predict recurrence of localized stage I non-small cell lung cancer after surgical resection
    • doi:10.1158/0008-5472.CAN-09-3153
    • Patnaik, S. K., Kannisto, E., Knudsen, S., and Yendamuri, S. (2010). Evaluation of microRNA expression profiles that may predict recurrence of localized stage I non-small cell lung cancer after surgical resection. Cancer Res. 70, 36-45. doi:10.1158/0008-5472.CAN-09-3153.
    • (2010) Cancer Res. , vol.70 , pp. 36-45
    • Patnaik, S.K.1    Kannisto, E.2    Knudsen, S.3    Yendamuri, S.4
  • 57
    • 0034992521 scopus 로고    scopus 로고
    • The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
    • doi:10.1677/erc.0.0080011
    • Prenzel, N., Fischer, O. M., Streit, S., Hart, S., and Ullrich, A. (2001). The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr. Relat. Cancer 8, 11-31. doi:10.1677/erc.0.0080011.
    • (2001) Endocr. Relat. Cancer , vol.8 , pp. 11-31
    • Prenzel, N.1    Fischer, O.M.2    Streit, S.3    Hart, S.4    Ullrich, A.5
  • 59
    • 80052698948 scopus 로고    scopus 로고
    • Liposomal delivery of microRNA-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells
    • doi:10.1158/1535-7163.MCT-11-0220
    • Rai, K., Takigawa, N., Ito, S., Kashihara, H., Ichihara, E., Yasuda, T., et al. (2011). Liposomal delivery of microRNA-7-expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells. Mol. Cancer Ther. 10, 1720-1727. doi:10.1158/1535-7163.MCT-11-0220.
    • (2011) Mol. Cancer Ther. , vol.10 , pp. 1720-1727
    • Rai, K.1    Takigawa, N.2    Ito, S.3    Kashihara, H.4    Ichihara, E.5    Yasuda, T.6
  • 60
    • 67651002796 scopus 로고    scopus 로고
    • MicroRNA classifiers for predicting prognosis of squamous cell lung cancer
    • doi:10.1158/0008-5472.CAN-09-0587
    • Raponi, M., Dossey, L., Jatkoe, T., Wu, X., Chen, G., Fan, H., et al. (2009). MicroRNA classifiers for predicting prognosis of squamous cell lung cancer. Cancer Res. 69, 5776-5783. doi:10.1158/0008-5472.CAN-09-0587.
    • (2009) Cancer Res. , vol.69 , pp. 5776-5783
    • Raponi, M.1    Dossey, L.2    Jatkoe, T.3    Wu, X.4    Chen, G.5    Fan, H.6
  • 61
    • 84866541922 scopus 로고    scopus 로고
    • MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma
    • doi:10.1038/onc.2011.578
    • Rothschild, S. I., Tschan, M. P., Federzoni, E. A., Jaggi, R., Fey, M. F., Gugger, M., et al. (2012a). MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma. Oncogene 31, 4221-4232. doi:10.1038/onc.2011.578.
    • (2012) Oncogene , vol.31 , pp. 4221-4232
    • Rothschild, S.I.1    Tschan, M.P.2    Federzoni, E.A.3    Jaggi, R.4    Fey, M.F.5    Gugger, M.6
  • 62
    • 84862856363 scopus 로고    scopus 로고
    • MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma
    • doi:10.1097/JTO.0b013e31824fe976
    • Rothschild, S. I., Tschan, M. P., Jaggi, R., Fey, M. F., Gugger, M., and Gautschi, O. (2012b). MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma. J. Thorac. Oncol. 7, 1069-1077. doi:10.1097/JTO.0b013e31824fe976.
    • (2012) J. Thorac. Oncol. , vol.7 , pp. 1069-1077
    • Rothschild, S.I.1    Tschan, M.P.2    Jaggi, R.3    Fey, M.F.4    Gugger, M.5    Gautschi, O.6
  • 63
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • doi:10.1016/j.ccr.2006.04.020
    • Saito, Y., Liang, G., Egger, G., Friedman, J. M., Chuang, J. C., Coetzee, G. A., et al. (2006). Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9, 435-443. doi:10.1016/j.ccr.2006.04.020.
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6
  • 64
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
    • doi:10.1158/0008-5472.CAN-07-2462
    • Sampson, V. B., Rong, N. H., Han, J., Yang, Q., Aris, V., Soteropoulos, P., et al. (2007). MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res. 6, 9762-9770. doi:10.1158/0008-5472.CAN-07-2462.
    • (2007) Cancer Res. , vol.6 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3    Yang, Q.4    Aris, V.5    Soteropoulos, P.6
  • 65
    • 64049115311 scopus 로고    scopus 로고
    • The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies
    • doi:10.1634/theoncologist.2008-0232
    • Scagliotti, G., Hanna, N., Fossella, F., Sugarman, K., Blatter, J., Peterson, P., et al. (2009). The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies. Oncologist 14, 253-263. doi:10.1634/theoncologist.2008-0232.
    • (2009) Oncologist , vol.14 , pp. 253-263
    • Scagliotti, G.1    Hanna, N.2    Fossella, F.3    Sugarman, K.4    Blatter, J.5    Peterson, P.6
  • 67
    • 67749110399 scopus 로고    scopus 로고
    • MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers
    • doi:10.1073/pnas.0905234106
    • Seike, M., Goto, A., Okano, T., Bowman, E. D., Schetter, A. J., Horikawa, I., et al. (2009). MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers. Proc. Natl. Acad. Sci. U.S.A. 106, 12085-12090. doi:10.1073/pnas.0905234106.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 12085-12090
    • Seike, M.1    Goto, A.2    Okano, T.3    Bowman, E.D.4    Schetter, A.J.5    Horikawa, I.6
  • 68
    • 76349095132 scopus 로고    scopus 로고
    • Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
    • doi:10.1038/onc.2009.441
    • Semenza, G. L. (2010). Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 29, 625-634. doi:10.1038/onc.2009.441.
    • (2010) Oncogene , vol.29 , pp. 625-634
    • Semenza, G.L.1
  • 69
    • 79953178293 scopus 로고    scopus 로고
    • Plasma microRNAs as potential biomarkers for non-small-cell lung cancer
    • doi:10.1038/labinvest.2010.194
    • Shen, J., Todd, N. W., Zhang, H., Yu, L., Lingxiao, X., Mei, Y., et al. (2011). Plasma microRNAs as potential biomarkers for non-small-cell lung cancer. Lab. Invest. 91, 579-587. doi:10.1038/labinvest.2010.194.
    • (2011) Lab. Invest. , vol.91 , pp. 579-587
    • Shen, J.1    Todd, N.W.2    Zhang, H.3    Yu, L.4    Lingxiao, X.5    Mei, Y.6
  • 70
    • 77952879648 scopus 로고    scopus 로고
    • Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro
    • doi:10.1016/j.bbrc.2010.04.127
    • Sun, Y., Fang, R., Li, C., Li, L., Li, F., Ye, X., et al. (2010). Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro. Biochem. Biophys. Res. Commun. 396, 501-507. doi:10.1016/j.bbrc.2010.04.127.
    • (2010) Biochem. Biophys. Res. Commun. , vol.396 , pp. 501-507
    • Sun, Y.1    Fang, R.2    Li, C.3    Li, L.4    Li, F.5    Ye, X.6
  • 71
    • 48649102010 scopus 로고    scopus 로고
    • Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster
    • doi:10.1158/0008-5472.CAN-07-6460
    • Taguchi, A., Yanagisawa, K., Tanaka, M., Cao, K., Matsuyama, Y., Goto, H., et al. (2008). Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster. Cancer Res. 68, 5540-5545. doi:10.1158/0008-5472.CAN-07-6460.
    • (2008) Cancer Res. , vol.68 , pp. 5540-5545
    • Taguchi, A.1    Yanagisawa, K.2    Tanaka, M.3    Cao, K.4    Matsuyama, Y.5    Goto, H.6
  • 72
    • 68949198148 scopus 로고    scopus 로고
    • MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines
    • doi:10.1371/journal.pone.0006677
    • Takahashi, Y., Forrest, A. R., Maeno, E., Hashimoto, T., Daub, C. O., and Yasuda, J. (2009). MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines. PLoS ONE 4:e6677. doi:10.1371/journal.pone.0006677.
    • (2009) PLoS ONE , vol.4
    • Takahashi, Y.1    Forrest, A.R.2    Maeno, E.3    Hashimoto, T.4    Daub, C.O.5    Yasuda, J.6
  • 73
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • doi:10.1158/0008-5472.CAN-04-0637
    • Takamizawa, J., Konishi, H., Yanagisawa, K., Tomida, S., Osada, H., Endoh, H., et al. (2004). Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 64, 3753-3756. doi:10.1158/0008-5472.CAN-04-0637.
    • (2004) Cancer Res. , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3    Tomida, S.4    Osada, H.5    Endoh, H.6
  • 74
    • 80455173422 scopus 로고    scopus 로고
    • A 5-microRNA signature for lung squamous cell carcinoma diagnosis and hsa-miR-31 for prognosis
    • doi:10.1158/1078-0432.CCR-11-0419
    • Tan, X., Qin, W., Zhang, L., Hang, J., Li, B., Zhang, C., et al. (2011). A 5-microRNA signature for lung squamous cell carcinoma diagnosis and hsa-miR-31 for prognosis. Clin. Cancer Res. 17, 6802-6811. doi:10.1158/1078-0432.CCR-11-0419.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 6802-6811
    • Tan, X.1    Qin, W.2    Zhang, L.3    Hang, J.4    Li, B.5    Zhang, C.6
  • 75
    • 77949658280 scopus 로고    scopus 로고
    • Regression of murine lung tumors by the let-7 microRNA
    • doi:10.1038/onc.2009.445
    • Trang, P., Medina, P. P., Wiggins, J. F., Ruffino, L., Kelnar, K., Omotola, M., et al. (2010). Regression of murine lung tumors by the let-7 microRNA. Oncogene 29, 1580-1587. doi:10.1038/onc.2009.445.
    • (2010) Oncogene , vol.29 , pp. 1580-1587
    • Trang, P.1    Medina, P.P.2    Wiggins, J.F.3    Ruffino, L.4    Kelnar, K.5    Omotola, M.6
  • 76
    • 39749143354 scopus 로고    scopus 로고
    • Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters
    • doi:10.1016/j.cell.2008.02.019
    • Ventura, A., Young, A. G., Winslow, M. M., Lintault, L., Meissner, A., Erkeland, S. J., et al. (2008). Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 132, 875-886. doi:10.1016/j.cell.2008.02.019.
    • (2008) Cell , vol.132 , pp. 875-886
    • Ventura, A.1    Young, A.G.2    Winslow, M.M.3    Lintault, L.4    Meissner, A.5    Erkeland, S.J.6
  • 77
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • doi:10.1073/pnas.0510565103
    • Volinia, S., Calin, G. A., Liu, C. G., Ambs, S., Cimmino, A., Petrocca, F., et al. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. U.S.A. 103, 2257-2261. doi:10.1073/pnas.0510565103.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3    Ambs, S.4    Cimmino, A.5    Petrocca, F.6
  • 78
    • 78449296222 scopus 로고    scopus 로고
    • MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma
    • doi:10.1158/0008-5472.CAN-10-1348
    • Voortman, J., Goto, A., Mendiboure, J., Sohn, J. J., Schetter, A. J., Saito, M., et al. (2010). MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma. Cancer Res. 70, 8288-8298. doi:10.1158/0008-5472.CAN-10-1348.
    • (2010) Cancer Res. , vol.70 , pp. 8288-8298
    • Voortman, J.1    Goto, A.2    Mendiboure, J.3    Sohn, J.J.4    Schetter, A.J.5    Saito, M.6
  • 79
    • 70349229606 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-regulated miR-125a-5p-a metastatic inhibitor of lung cancer
    • doi:10.1111/j.1742-4658.2009.07238.x
    • Wang, G., Mao, W., Zheng, S., and Ye, J. (2009). Epidermal growth factor receptor-regulated miR-125a-5p-a metastatic inhibitor of lung cancer. FEBS J. 276, 5571-5578. doi:10.1111/j.1742-4658.2009.07238.x.
    • (2009) FEBS J. , vol.276 , pp. 5571-5578
    • Wang, G.1    Mao, W.2    Zheng, S.3    Ye, J.4
  • 80
    • 84863377480 scopus 로고    scopus 로고
    • MicroRNAs: novel biomarkers for lung cancer diagnosis, prediction and treatment
    • doi:10.1258/ebm.2011.011192
    • Wang, Q., Wang, S., Wang, H., Li, P., and Ma, Z. (2012). MicroRNAs: novel biomarkers for lung cancer diagnosis, prediction and treatment. Exp. Biol. Med. (Maywood) 237, 227-235. doi:10.1258/ebm.2011.011192.
    • (2012) Exp. Biol. Med. (Maywood) , vol.237 , pp. 227-235
    • Wang, Q.1    Wang, S.2    Wang, H.3    Li, P.4    Ma, Z.5
  • 81
    • 79958288052 scopus 로고    scopus 로고
    • MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14)
    • doi:10.1038/onc.2010.642
    • Wang, R., Wang, Z. X., Yang, J. S., Pan, X., De, W., and Chen, L. B. (2011). MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). Oncogene 30, 2644-2658. doi:10.1038/onc.2010.642.
    • (2011) Oncogene , vol.30 , pp. 2644-2658
    • Wang, R.1    Wang, Z.X.2    Yang, J.S.3    Pan, X.4    De, W.5    Chen, L.B.6
  • 82
    • 65549120766 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7
    • doi:10.1074/jbc.M804280200
    • Webster, R. J., Giles, K. M., Price, K. J., Zhang, P. M., Mattick, J. S., and Leedman, P. J. (2009). Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J. Biol. Chem. 284, 5731-5741. doi:10.1074/jbc.M804280200.
    • (2009) J. Biol. Chem. , vol.284 , pp. 5731-5741
    • Webster, R.J.1    Giles, K.M.2    Price, K.J.3    Zhang, P.M.4    Mattick, J.S.5    Leedman, P.J.6
  • 83
    • 37049019490 scopus 로고    scopus 로고
    • MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy
    • doi:10.1158/0008-5472.CAN-07-2858
    • Weidhaas, J. B., Babar, I., Nallur, S. M., Trang, P., Roush, S., Boehm, M., et al. (2007). MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy. Cancer Res. 67, 11111-11116. doi:10.1158/0008-5472.CAN-07-2858.
    • (2007) Cancer Res. , vol.67 , pp. 11111-11116
    • Weidhaas, J.B.1    Babar, I.2    Nallur, S.M.3    Trang, P.4    Roush, S.5    Boehm, M.6
  • 84
    • 44849091213 scopus 로고    scopus 로고
    • EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines
    • doi:10.1093/annonc/mdn006
    • Weiss, G. J., Bemis, L. T., Nakajima, E., Sugita, M., Birks, D. K., Robinson, W. A., et al. (2008). EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines. Ann. Oncol. 19, 1053-1059. doi:10.1093/annonc/mdn006.
    • (2008) Ann. Oncol. , vol.19 , pp. 1053-1059
    • Weiss, G.J.1    Bemis, L.T.2    Nakajima, E.3    Sugita, M.4    Birks, D.K.5    Robinson, W.A.6
  • 86
    • 72449187466 scopus 로고    scopus 로고
    • Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer
    • doi:10.1016/j.lungcan.2009.04.004
    • Xie, Y., Todd, N. W., Liu, Z., Zhan, M., Fang, H., Peng, H., et al. (2010). Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer. Lung Cancer 67, 170-176. doi:10.1016/j.lungcan.2009.04.004.
    • (2010) Lung Cancer , vol.67 , pp. 170-176
    • Xie, Y.1    Todd, N.W.2    Liu, Z.3    Zhan, M.4    Fang, H.5    Peng, H.6
  • 87
    • 77955175327 scopus 로고    scopus 로고
    • Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers
    • doi:10.1038/modpathol.2010.111
    • Xing, L., Todd, N. W., Yu, L., Fang, H., and Jiang, F. (2010). Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers. Mod. Pathol. 23, 1157-1164. doi:10.1038/modpathol.2010.111.
    • (2010) Mod. Pathol. , vol.23 , pp. 1157-1164
    • Xing, L.1    Todd, N.W.2    Yu, L.3    Fang, H.4    Jiang, F.5
  • 88
    • 68049117231 scopus 로고    scopus 로고
    • MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors
    • doi:10.1158/0008-5472.CAN-08-4517
    • Xu, H. I., Cheung, Y., Guo, H. F., and Cheung, N. K. (2009). MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors. Cancer Res. 69, 6275-6281. doi:10.1158/0008-5472.CAN-08-4517.
    • (2009) Cancer Res. , vol.69 , pp. 6275-6281
    • Xu, H.I.1    Cheung, Y.2    Guo, H.F.3    Cheung, N.K.4
  • 89
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara, N., Caplen, N., Bowman, E., Seike, M., Kumamoto, K., Yi, M., et al. (2006). Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9, 189-198.
    • (2006) Cancer Cell , vol.9 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3    Seike, M.4    Kumamoto, K.5    Yi, M.6
  • 90
    • 77955516533 scopus 로고    scopus 로고
    • Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers
    • doi:10.1002/ijc.25289
    • Yu, L., Todd, N. W., Xing, L., Xie, Y., Zhang, H., Liu, Z., et al. (2010). Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers. Int. J. Cancer 127, 2870-2878. doi:10.1002/ijc.25289.
    • (2010) Int. J. Cancer , vol.127 , pp. 2870-2878
    • Yu, L.1    Todd, N.W.2    Xing, L.3    Xie, Y.4    Zhang, H.5    Liu, Z.6
  • 91
    • 37349096992 scopus 로고    scopus 로고
    • MicroRNA signature predicts survival and relapse in lung cancer
    • doi:10.1016/j.ccr.2007.12.008
    • Yu, S. L., Chen, H. Y., Chang, G. C., Chen, C. Y., Chen, H. W., Singh, S., et al. (2008). MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell 13, 48-57. doi:10.1016/j.ccr.2007.12.008.
    • (2008) Cancer Cell , vol.13 , pp. 48-57
    • Yu, S.L.1    Chen, H.Y.2    Chang, G.C.3    Chen, C.Y.4    Chen, H.W.5    Singh, S.6
  • 92
    • 79953029421 scopus 로고    scopus 로고
    • MicroRNA-101 exerts tumor-suppressive functions in non-small cell lung cancer through directly targeting enhancer of zeste homolog 2
    • doi:10.1097/JTO.0b013e318208eb35
    • Zhang, J. G., Guo, J. F., Liu, D. L., Liu, Q., and Wang, J. J. (2011). MicroRNA-101 exerts tumor-suppressive functions in non-small cell lung cancer through directly targeting enhancer of zeste homolog 2. J. Thorac. Oncol. 6, 671-678. doi:10.1097/JTO.0b013e318208eb35.
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 671-678
    • Zhang, J.G.1    Guo, J.F.2    Liu, D.L.3    Liu, Q.4    Wang, J.J.5
  • 93
    • 77949912309 scopus 로고    scopus 로고
    • MicroRNAs reduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer
    • doi:10.1016/j.cbi.2010.01.025
    • Zhong, M., Ma, X., Sun, C., and Chen, L. (2010). MicroRNAs reduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer. Chem. Biol. Interact. 184, 431-438. doi:10.1016/j.cbi.2010.01.025.
    • (2010) Chem. Biol. Interact. , vol.184 , pp. 431-438
    • Zhong, M.1    Ma, X.2    Sun, C.3    Chen, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.