AIDing chromatin and transcription-coupled orchestration of immunoglobulin class-switch recombination

Frontiers in Immunology

Volumn 5, Issue MAR, 2014, Pages

  Vaidyanathan, Bharat ^a,b   Yen, Wei Feng ^a,b   Pucella, Joseph N ^b   Chaudhuri, Jayanta ^a,b  

^a Weill Cornell Medical Center   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Class switching; Cytidine deamination; DNA recombination; DNA repair; R loops

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; APE1 ENDONUCLEASE; DNA POLYMERASE; HEAT SHOCK PROTEIN 90; HISTONE H2AX; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; MICRORNA; MICRORNA 155; MICRORNA 181B; MICRORNA 361; MISMATCH REPAIR PROTEIN PMS2; MYC PROTEIN; NUCLEOLIN; NUCLEOPHOSMIN; PEPTIDES AND PROTEINS; POLYPYRIMIDINE TRACT BINDING PROTEIN 2; PROTEIN KINASE C; PROTEIN MLH1; RNA POLYMERASE II; SMAD3 PROTEIN; SMAD4 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR E2A; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR PAX5; UNCLASSIFIED DRUG; UNINDEXED DRUG;

B LYMPHOCYTE ACTIVATION; CLASS SWITCH RECOMBINATION; DEMETHYLATION; DNA DAMAGE; DNA RECOMBINATION; DNA REPAIR; GENE REARRANGEMENT; GENETIC RECOMBINATION; HELICOBACTER INFECTION; HISTONE METHYLATION; HUMAN; IMMUNE RESPONSE; NONHUMAN; NUCLEAR EXPORT SIGNAL; NUCLEAR LOCALIZATION SIGNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REVIEW;

EID: 84897953519     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00120     Document Type: Review

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