Activation induced deaminase: How much and where?

Seminars in Immunology

Volumn 24, Issue 4, 2012, Pages 246-254

  Orthwein, Alexandre ^a,b   Di Noia, Javier M ^a,b,c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Activation induced deaminase (AID); Antibody gene diversification; B lymphocyte; Class switch recombination; Humoral immunity; Protein stability; Somatic hypermutation; Subcellular localization

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; CHAPERONE; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; IMMUNOGLOBULIN M; MESSENGER RNA; PROTEASOME; PROTEIN BCL 6;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADAPTIVE IMMUNITY; ANTIBODY SPECIFICITY; APOPTOSIS; ARTHRITIS; AUTOIMMUNITY; B LYMPHOCYTE; BREAST CANCER; BURKITT LYMPHOMA; CANCER CELL CULTURE; CELL INTERACTION; CELL MATURATION; CELL TRANSFORMATION; CELL TYPE; CELLULAR DISTRIBUTION; CHRONIC MYELOID LEUKEMIA; CLONAL EVOLUTION; DISEASE COURSE; DISEASE MODEL; DNA DAMAGE; EMBRYONIC STEM CELL; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STABILITY; EPIGENETICS; FOLLICULAR LYMPHOMA; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TRANSLOCATION; GENETIC RECOMBINATION; GENETIC TRANSCRIPTION; GENOME; GERMINAL CENTER; HAPLOINSUFFICIENCY; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LARGE CELL LYMPHOMA; LUPUS VULGARIS; LYMPHOMA; NONHUMAN; NUCLEAR EXPORT SIGNAL; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; OOCYTE; PHILADELPHIA CHROMOSOME POSITIVE CELL; PRIMORDIAL GERM CELL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SOMATIC HYPERMUTATION; SPERMATOCYTE; TRANSCRIPTION REGULATION; TRANSGENE; TRANSGENIC MOUSE; TRANSLATION REGULATION; TUMOR CELL LINE;

ANIMALS; AUTOIMMUNITY; B-LYMPHOCYTES; CYTIDINE DEAMINASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HAPLOTYPES; HUMANS; NEOPLASMS;

EID: 84865180284     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2012.05.001     Document Type: Review

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