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Volumn 210, Issue 1, 2013, Pages 115-123

Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching

Author keywords

[No Author keywords available]

Indexed keywords

BLOOM SYNDROME HELICASE; CTIP PROTEIN; EXONUCLEASE 1; HISTONE H2AX; IMMUNOGLOBULIN CLASS; MRE11 PROTEIN; PROTEIN; RECQ HELICASE; UNCLASSIFIED DRUG; WERNER SYNDROME PROTEIN;

EID: 84874543760     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121975     Document Type: Article
Times cited : (43)

References (50)
  • 1
    • 79952127438 scopus 로고    scopus 로고
    • Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
    • Aggarwal, M., J.A. Sommers, R.H. Shoemaker, and R.M. Brosh Jr. 2011. Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress. Proc. Natl. Acad. Sci. USA. 108:1525-1530. http://dx.doi.org/10.1073/pnas.1006423108
    • (2011) Proc. Natl. Acad. Sci. USA. , vol.108 , pp. 1525-1530
    • Aggarwal, M.1    Sommers, J.A.2    Shoemaker, R.H.3    Brosh, R.M.4
  • 2
    • 59849125952 scopus 로고    scopus 로고
    • Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage
    • Babbe, H., J. McMenamin, E. Hobeika, J. Wang, S.J. Rodig, M. Reth, and P. Leder. 2009. Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage. J. Immunol. 182:347-360.
    • (2009) J. Immunol. , vol.182 , pp. 347-360
    • Babbe, H.1    Mcmenamin, J.2    Hobeika, E.3    Wang, J.4    Rodig, S.J.5    Reth, M.6    Leder, P.7
  • 3
    • 1142299546 scopus 로고    scopus 로고
    • Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice
    • Bardwell, P.D., C.J. Woo, K. Wei, Z. Li, A. Martin, S.Z. Sack, T. Parris, W. Edelmann, and M.D. Scharff. 2004. Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. Nat. Immunol. 5:224-229. http://dx.doi.org/10.1038/ni1031
    • (2004) Nat. Immunol , vol.5 , pp. 224-229
    • Bardwell, P.D.1    Woo, C.J.2    Wei, K.3    Li, Z.4    Martin, A.5    Sack, S.6    Parris, T.7    Edelmann, W.8    Scharff, M.D.9
  • 4
    • 78649938817 scopus 로고    scopus 로고
    • ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage
    • 3:rs3
    • Bensimon, A., A. Schmidt, Y. Ziv, R. Elkon, S.Y. Wang, D.J. Chen, R. Aebersold, and Y. Shiloh. 2010. ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage. Sci. Signal. 3:rs3. http://dx.doi.org/10.1126/scisignal.2001034
    • (2010) Sci. Signal.
    • Bensimon, A.1    Schmidt, A.2    Ziv, Y.3    Elkon, R.4    Wang, S.Y.5    Chen, D.J.6    Aebersold, R.7    Shiloh, Y.8
  • 7
    • 77951057068 scopus 로고    scopus 로고
    • 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
    • Bothmer, A., D.F. Robbiani, N. Feldhahn, A. Gazumyan, A. Nussenzweig, and M.C. Nussenzweig. 2010. 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination. J. Exp. Med. 207:855-865. http://dx.doi.org/10.1084/jem.20100244
    • (2010) J. Exp. Med. , vol.207 , pp. 855-865
    • Bothmer, A.1    Robbiani, D.F.2    Feldhahn, N.3    Gazumyan, A.4    Nussenzweig, A.5    Nussenzweig, M.C.6
  • 9
    • 38049075962 scopus 로고    scopus 로고
    • Human premature aging, DNA repair and RecQ helicases
    • Brosh, R.M. Jr., and V.A. Bohr. 2007. Human premature aging, DNA repair and RecQ helicases. Nucleic Acids Res. 35:7527-7544. http://dx.doi.org/10.1093/nar/gkm1008
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7527-7544
    • Brosh, R.M.1    Bohr, V.A.2
  • 12
    • 17644375501 scopus 로고    scopus 로고
    • Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency
    • Chen, P.L., F. Liu, S. Cai, X. Lin, A. Li, Y. Chen, B. Gu, E.Y. Lee, and W.H. Lee. 2005. Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency. Mol. Cell. Biol. 25:3535-3542. http://dx.doi.org/10.1128/MCB.25.9.3535-3542.2005
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 3535-3542
    • Chen, P.L.1    Liu, F.2    Cai, S.3    Lin, X.4    Li, A.5    Chen, Y.6    Gu, B.7    Lee, E.Y.8    Lee, W.H.9
  • 13
    • 33747751867 scopus 로고    scopus 로고
    • Mutation of the murine Bloom's syndrome gene produces global genome destabilization
    • Chester, N., H. Babbe, J. Pinkas, C. Manning, and P. Leder. 2006. Mutation of the murine Bloom's syndrome gene produces global genome destabilization. Mol. Cell. Biol. 26:6713-6726. http://dx.doi.org/10.1128/MCB.00296-06
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 6713-6726
    • Chester, N.1    Babbe, H.2    Pinkas, J.3    Manning, C.4    Leder, P.5
  • 14
    • 80053558376 scopus 로고    scopus 로고
    • Genomewide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells
    • Chiarle, R., Y. Zhang, R.L. Frock, S.M. Lewis, B. Molinie, Y.J. Ho, D.R. Myers, V.W. Choi, M. Compagno, D.J. Malkin, et al. 2011. Genomewide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells. Cell. 147:107-119. http://dx.doi.org/10.1016/j.cell.2011.07.049
    • (2011) Cell. , vol.147 , pp. 107-119
    • Chiarle, R.1    Zhang, Y.2    Frock, R.L.3    Lewis, S.M.4    Molinie, B.5    Ho, Y.J.6    Myers, D.R.7    Choi, V.W.8    Compagno, M.9    Malkin, D.J.10
  • 16
    • 33748144349 scopus 로고    scopus 로고
    • Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations
    • Franco, S., F.W. Alt, and J.P. Manis. 2006. Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations. DNA Repair (Amst.). 5:1030-1041. http://dx.doi.org/10.1016/j.dnarep.2006.05.024
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 1030-1041
    • Franco, S.1    Alt, F.W.2    Manis, J.P.3
  • 18
    • 79953032797 scopus 로고    scopus 로고
    • Mechanisms that promote and suppress chromosomal translocations in lymphocytes
    • Gostissa, M., F.W. Alt, and R. Chiarle. 2011. Mechanisms that promote and suppress chromosomal translocations in lymphocytes. Annu. Rev. Immunol. 29: 319-350. http://dx.doi.org/10.1146/annurev-immunol-031210-101329
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 319-350
    • Gostissa, M.1    Alt, F.W.2    Chiarle, R.3
  • 19
    • 53649090109 scopus 로고    scopus 로고
    • DNA helicases Sgs1 and BLM promote DNA double-strand break resection
    • Gravel, S., J.R. Chapman, C. Magill, and S.P. Jackson. 2008. DNA helicases Sgs1 and BLM promote DNA double-strand break resection. Genes Dev. 22:2767-2772. http://dx.doi.org/10.1101/gad.503108
    • (2008) Genes Dev. , vol.22 , pp. 2767-2772
    • Gravel, S.1    Chapman, J.R.2    Magill, C.3    Jackson, S.P.4
  • 23
    • 78650988959 scopus 로고    scopus 로고
    • CtIP promotes microhomology-mediated alternative end joining during class-switch recombination
    • Lee-Theilen, M., A.J. Matthews, D. Kelly, S. Zheng, and J. Chaudhuri. 2011. CtIP promotes microhomology-mediated alternative end joining during class-switch recombination. Nat. Struct. Mol. Biol. 18:75-79. http://dx.doi.org/10.1038/nsmb.1942
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 75-79
    • Lee-Theilen, M.1    Matthews, A.J.2    Kelly, D.3    Zheng, S.4    Chaudhuri, J.5
  • 24
    • 0034644220 scopus 로고    scopus 로고
    • Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
    • Li, S., N.S. Ting, L. Zheng, P.L. Chen, Y. Ziv, Y. Shiloh, E.Y. Lee, and W.H. Lee. 2000. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature. 406:210-215. http://dx.doi.org/10.1038/35018134
    • (2000) Nature. , vol.406 , pp. 210-215
    • Li, S.1    Ting, N.S.2    Zheng, L.3    Chen, P.L.4    Ziv, Y.5    Shiloh, Y.6    Lee, E.Y.7    Lee, W.H.8
  • 26
    • 2442707746 scopus 로고    scopus 로고
    • 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
    • Manis, J.P., J.C. Morales, Z. Xia, J.L. Kutok, F.W. Alt, and P.B. Carpenter. 2004. 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat. Immunol. 5:481-487. http://dx.doi.org/10.1038/ni1067
    • (2004) Nat. Immunol , vol.5 , pp. 481-487
    • Manis, J.P.1    Morales, J.C.2    Xia, Z.3    Kutok, J.L.4    Alt, F.W.5    Carpenter, P.B.6
  • 28
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • Mimitou, E.P., and L.S. Symington. 2008. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature. 455:770-774. http://dx.doi.org/10.1038/nature07312
    • (2008) Nature. , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 29
    • 33947581390 scopus 로고    scopus 로고
    • The impact of translocations and gene fusions on cancer causation
    • Mitelman, F., B. Johansson, and F. Mertens. 2007. The impact of translocations and gene fusions on cancer causation. Nat. Rev. Cancer. 7:233-245. http://dx.doi.org/10.1038/nrc2091
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 233-245
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 30
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activationinduced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activationinduced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 102:553-563. http://dx.doi.org/10.1016/S0092-8674(00)00078-7
    • (2000) Cell. , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 31
    • 13444259474 scopus 로고    scopus 로고
    • Somatic hypermutation at AT pairs: polymerase error versus dUTP incorporation
    • Neuberger, M.S., J.M. Di Noia, R.C. Beale, G.T. Williams, Z. Yang, and C. Rada. 2005. Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation. Nat. Rev. Immunol. 5:171-178. http://dx.doi.org/10.1038/nri1553
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 171-178
    • Neuberger, M.S.1    Di Noia, J.M.2    Beale, R.C.3    Williams, G.T.4    Yang, Z.5    Rada, C.6
  • 32
    • 79951688343 scopus 로고    scopus 로고
    • BLM-DNA2- RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
    • Nimonkar, A.V., J. Genschel, E. Kinoshita, P. Polaczek, J.L. Campbell, C. Wyman, P. Modrich, and S.C. Kowalczykowski. 2011. BLM-DNA2- RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair. Genes Dev. 25: 350-362. http://dx.doi.org/10.1101/gad.2003811
    • (2011) Genes Dev. , vol.25 , pp. 350-362
    • Nimonkar, A.V.1    Genschel, J.2    Kinoshita, E.3    Polaczek, P.4    Campbell, J.L.5    Wyman, C.6    Modrich, P.7    Kowalczykowski, S.C.8
  • 33
    • 84860389035 scopus 로고    scopus 로고
    • 53BP1-mediated DNA double strand break repair: insert bad pun here
    • Noon, A.T., and A.A. Goodarzi. 2011. 53BP1-mediated DNA double strand break repair: insert bad pun here. DNA Repair (Amst.). 10:1071-1076. http://dx.doi.org/10.1016/j.dnarep.2011.07.012
    • (2011) DNA Repair (Amst.) , vol.10 , pp. 1071-1076
    • Noon, A.T.1    Goodarzi, A.A.2
  • 34
    • 77950955761 scopus 로고    scopus 로고
    • Origin of chromosomal translocations in lymphoid cancer
    • Nussenzweig, A., and M.C. Nussenzweig. 2010. Origin of chromosomal translocations in lymphoid cancer. Cell. 141:27-38. http://dx.doi.org/10.1016/j.cell.2010.03.016
    • (2010) Cell. , vol.141 , pp. 27-38
    • Nussenzweig, A.1    Nussenzweig, M.C.2
  • 35
    • 29244437908 scopus 로고    scopus 로고
    • The role of double-strand break repair - insights from human genetics
    • O'Driscoll, M., and P.A. Jeggo. 2006. The role of double-strand break repair - insights from human genetics. Nat. Rev. Genet. 7:45-54. http://dx.doi.org/10.1038/nrg1746
    • (2006) Nat. Rev. Genet , vol.7 , pp. 45-54
    • O'Driscoll, M.1    Jeggo, P.A.2
  • 37
    • 8644238314 scopus 로고    scopus 로고
    • ATM is required for efficient recombination between immunoglobulin switch regions
    • Reina-San-Martin, B., H.T. Chen, A. Nussenzweig, and M.C. Nussenzweig. 2004. ATM is required for efficient recombination between immunoglobulin switch regions. J. Exp. Med. 200:1103-1110. http://dx.doi.org/10.1084/jem.20041162
    • (2004) J. Exp. Med. , vol.200 , pp. 1103-1110
    • Reina-San-Martin, B.1    Chen, H.T.2    Nussenzweig, A.3    Nussenzweig, M.C.4
  • 38
    • 0030818183 scopus 로고    scopus 로고
    • B lymphocyte-specific, Cre-mediated mutagenesis in mice
    • Rickert, R.C., J. Roes, and K. Rajewsky. 1997. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res. 25:1317-1318. http://dx.doi.org/10.1093/nar/25.6.1317
    • (1997) Nucleic Acids Res , vol.25 , pp. 1317-1318
    • Rickert, R.C.1    Roes, J.2    Rajewsky, K.3
  • 39
    • 84873322531 scopus 로고    scopus 로고
    • Chromosome Translocation, B Cell Lymphoma, and Activation-induced Cytidine Deaminase
    • Robbiani, D.F., and M.C. Nussenzweig. 2012. Chromosome Translocation, B Cell Lymphoma, and Activation-induced Cytidine Deaminase. Annu. Rev. Pathol.
    • (2012) Annu. Rev. Pathol
    • Robbiani, D.F.1    Nussenzweig, M.C.2
  • 42
    • 42649123314 scopus 로고    scopus 로고
    • Mechanism and regulation of class switch recombination
    • Stavnezer, J., J.E. Guikema, and C.E. Schrader. 2008. Mechanism and regulation of class switch recombination. Annu. Rev. Immunol. 26:261-292. http://dx.doi.org/10.1146/annurev.immunol.26.021607.090248
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 261-292
    • Stavnezer, J.1    Guikema, J.E.2    Schrader, C.E.3
  • 43
    • 80755187806 scopus 로고    scopus 로고
    • Double-strand break end resection and repair pathway choice
    • Symington, L.S., and J. Gautier. 2011. Double-strand break end resection and repair pathway choice. Annu. Rev. Genet. 45:247-271. http://dx.doi.org/10.1146/annurev-genet-110410-132435
    • (2011) Annu. Rev. Genet. , vol.45 , pp. 247-271
    • Symington, L.S.1    Gautier, J.2
  • 45
    • 0037364995 scopus 로고    scopus 로고
    • Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility
    • Wei, K., A.B. Clark, E. Wong, M.F. Kane, D.J. Mazur, T. Parris, N.K. Kolas, R. Russell, H. Hou Jr., B. Kneitz, et al. 2003. Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. Genes Dev. 17:603-614. http://dx.doi.org/10.1101/gad.1060603
    • (2003) Genes Dev. , vol.17 , pp. 603-614
    • Wei, K.1    Clark, A.B.2    Wong, E.3    Kane, M.F.4    Mazur, D.J.5    Parris, T.6    Kolas, N.K.7    Russell, R.8    Hou, H.9    Kneitz, B.10
  • 47
    • 0034674706 scopus 로고    scopus 로고
    • Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor
    • Yu, X., and R. Baer. 2000. Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor. J. Biol. Chem. 275:18541-18549. http://dx.doi.org/10.1074/jbc.M909494199
    • (2000) J. Biol. Chem. , vol.275 , pp. 18541-18549
    • Yu, X.1    Baer, R.2
  • 48
    • 78650995499 scopus 로고    scopus 로고
    • An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
    • Zhang, Y., and M. Jasin. 2011. An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway. Nat. Struct. Mol. Biol. 18:80-84. http://dx.doi.org/10.1038/nsmb.1940
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 80-84
    • Zhang, Y.1    Jasin, M.2
  • 49
    • 84862778059 scopus 로고    scopus 로고
    • Spatial organization of the mouse genome and its role in recurrent chromosomal translocations
    • Zhang, Y., R.P. McCord, Y.J. Ho, B.R. Lajoie, D.G. Hildebrand, A.C. Simon, M.S. Becker, F.W. Alt, and J. Dekker. 2012. Spatial organization of the mouse genome and its role in recurrent chromosomal translocations. Cell. 148:908-921. http://dx.doi.org/10.1016/j.cell.2012.02.002
    • (2012) Cell. , vol.148 , pp. 908-921
    • Zhang, Y.1    McCord, R.P.2    Ho, Y.J.3    Lajoie, B.R.4    Hildebrand, D.G.5    Simon, A.C.6    Becker, M.S.7    Alt, F.W.8    Dekker, J.9
  • 50
    • 51549095956 scopus 로고    scopus 로고
    • Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
    • Zhu, Z., W.H. Chung, E.Y. Shim, S.E. Lee, and G. Ira. 2008. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell. 134:981-994. http://dx.doi.org/10.1016/j.cell.2008.08.037
    • (2008) Cell. , vol.134 , pp. 981-994
    • Zhu, Z.1    Chung, W.H.2    Shim, E.Y.3    Lee, S.E.4    Ira, G.5


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