Genetic and epigenetic basis of Treg cell development and function: From a FoxP3-centered view to an epigenome-defined view of natural Treg cells

Immunological Reviews

Volumn 259, Issue 1, 2014, Pages 192-205

  Morikawa, Hiromasa ^a   Sakaguchi, Shimon ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

DNA methylation; Epigenome; FoxP3; Regulatory T cells

Indexed keywords

BIOLOGICAL MARKER; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IKZF4 PROTEIN; INTERLEUKIN 2 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL HETEROGENEITY; CELL MATURATION; DNA METHYLATION; ENHANCER REGION; EPIGENETICS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOME; HUMAN; IMMUNE SYSTEM; LYMPHOCYTE FUNCTION; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN STABILITY; REGULATORY T LYMPHOCYTE; STABLE EXPRESSION; STEADY STATE; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE;

DNA METHYLATION; EPIGENOME; FOXP3; REGULATORY T CELLS;

ANIMALS; EPIGENESIS, GENETIC; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMANS; SELF TOLERANCE; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTOME;

EID: 84897935715     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12174     Document Type: Article

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