메뉴 건너뛰기




Volumn 241, Issue 1, 2011, Pages 260-268

Regulatory T cells and Foxp3

Author keywords

Foxp3; Inflammation; Regulatory T cells; Tolerance

Indexed keywords

TRANSCRIPTION FACTOR FOXP3;

EID: 79954486763     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/j.1600-065X.2011.01018.x     Document Type: Article
Times cited : (653)

References (77)
  • 1
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 2
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi T, et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2000;192:303-310.
    • (2000) J Exp Med , vol.192 , pp. 303-310
    • Takahashi, T.1
  • 3
    • 0021997185 scopus 로고
    • Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
    • Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J Exp Med 1985;161:72-87.
    • (1985) J Exp Med , vol.161 , pp. 72-87
    • Sakaguchi, S.1    Fukuma, K.2    Kuribayashi, K.3    Masuda, T.4
  • 4
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
    • Asano M, Toda M, Sakaguchi N, Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med 1996;184:387-396.
    • (1996) J Exp Med , vol.184 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3    Sakaguchi, S.4
  • 5
    • 7144259082 scopus 로고    scopus 로고
    • Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
    • Papiernik M, de Moraes ML, Pontoux C, Vasseur F, Penit C. Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int Immunol 1998;10:371-378.
    • (1998) Int Immunol , vol.10 , pp. 371-378
    • Papiernik, M.1    de Moraes, M.L.2    Pontoux, C.3    Vasseur, F.4    Penit, C.5
  • 7
    • 0031939403 scopus 로고    scopus 로고
    • CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
    • Suri-Payer E, Amar AZ, Thornton AM, Shevach EM. CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol 1998;160:1212-1218.
    • (1998) J Immunol , vol.160 , pp. 1212-1218
    • Suri-Payer, E.1    Amar, A.Z.2    Thornton, A.M.3    Shevach, E.M.4
  • 8
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow ME, et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 2001;27:68-73.
    • (2001) Nat Genet , vol.27 , pp. 68-73
    • Brunkow, M.E.1
  • 9
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • Bennett CL, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001;27:20-21.
    • (2001) Nat Genet , vol.27 , pp. 20-21
    • Bennett, C.L.1
  • 10
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin RS, et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001;27:18-20.
    • (2001) Nat Genet , vol.27 , pp. 18-20
    • Wildin, R.S.1
  • 11
    • 0034526617 scopus 로고    scopus 로고
    • JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
    • Chatila TA, et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 2000;106:R75-R81.
    • (2000) J Clin Invest , vol.106
    • Chatila, T.A.1
  • 13
    • 0026043866 scopus 로고
    • Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education
    • Godfrey VL, Wilkinson JE, Rinchik EM, Russell LB. Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education. Proc Natl Acad Sci USA 1991;88:5528-5532.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5528-5532
    • Godfrey, V.L.1    Wilkinson, J.E.2    Rinchik, E.M.3    Russell, L.B.4
  • 14
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003;4:330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 15
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299: 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 16
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 2003;4:337-342.
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 18
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
    • Wan YY, Flavell RA. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc Natl Acad Sci USA 2005;102:5126-5131.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5126-5131
    • Wan, Y.Y.1    Flavell, R.A.2
  • 19
    • 26844450449 scopus 로고    scopus 로고
    • How defects in central tolerance impinge on a deficiency in regulatory T cells
    • Chen Z, Benoist C, Mathis D. How defects in central tolerance impinge on a deficiency in regulatory T cells. Proc Natl Acad Sci USA 2005;102:14735-14740.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14735-14740
    • Chen, Z.1    Benoist, C.2    Mathis, D.3
  • 20
    • 33645102841 scopus 로고    scopus 로고
    • An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires
    • Hsieh CS, Zheng Y, Liang Y, Fontenot JD, Rudensky AY. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat Immunol 2006;7:401-410.
    • (2006) Nat Immunol , vol.7 , pp. 401-410
    • Hsieh, C.S.1    Zheng, Y.2    Liang, Y.3    Fontenot, J.D.4    Rudensky, A.Y.5
  • 21
    • 45949099261 scopus 로고    scopus 로고
    • Cutting edge: broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells
    • Chen GY, Chen C, Wang L, Chang X, Zheng P, Liu Y. Cutting edge: broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells. J Immunol 2008;180:5163-5166.
    • (2008) J Immunol , vol.180 , pp. 5163-5166
    • Chen, G.Y.1    Chen, C.2    Wang, L.3    Chang, X.4    Zheng, P.5    Liu, Y.6
  • 22
    • 26844476814 scopus 로고    scopus 로고
    • The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis
    • Chang X, et al. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis. J Exp Med 2005;202:1141-1151.
    • (2005) J Exp Med , vol.202 , pp. 1141-1151
    • Chang, X.1
  • 23
    • 34250863911 scopus 로고    scopus 로고
    • FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene
    • Zuo T, et al. FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene. Cell 2007;129:1275-1286.
    • (2007) Cell , vol.129 , pp. 1275-1286
    • Zuo, T.1
  • 24
    • 70349466655 scopus 로고    scopus 로고
    • Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate
    • Wang L, et al. Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. Cancer Cell 2009;16:336-346.
    • (2009) Cancer Cell , vol.16 , pp. 336-346
    • Wang, L.1
  • 25
    • 76249088097 scopus 로고    scopus 로고
    • Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice
    • Kim J, et al. Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice. J Immunol 2009;183:7631-7634.
    • (2009) J Immunol , vol.183 , pp. 7631-7634
    • Kim, J.1
  • 26
    • 33947427514 scopus 로고    scopus 로고
    • Lack of Foxp3 function and expression in the thymic epithelium
    • Liston A, et al. Lack of Foxp3 function and expression in the thymic epithelium. J Exp Med 2007;204:475-480.
    • (2007) J Exp Med , vol.204 , pp. 475-480
    • Liston, A.1
  • 27
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim JM, Rasmussen JP, Rudensky AY. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol 2007;8:191-197.
    • (2007) Nat Immunol , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 28
    • 33846423147 scopus 로고    scopus 로고
    • Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
    • Lahl K, et al. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J Exp Med 2007;204:57-63.
    • (2007) J Exp Med , vol.204 , pp. 57-63
    • Lahl, K.1
  • 29
    • 65249089638 scopus 로고    scopus 로고
    • In vivo analysis of dendritic cell development and homeostasis
    • Liu K, et al. In vivo analysis of dendritic cell development and homeostasis. Science 2009;324:392-397.
    • (2009) Science , vol.324 , pp. 392-397
    • Liu, K.1
  • 30
    • 29244482759 scopus 로고    scopus 로고
    • Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
    • Tang Q, et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 2006;7:83-92.
    • (2006) Nat Immunol , vol.7 , pp. 83-92
    • Tang, Q.1
  • 31
    • 33645067654 scopus 로고    scopus 로고
    • Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo
    • Tadokoro CE, et al. Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. J Exp Med 2006;203:505-511.
    • (2006) J Exp Med , vol.203 , pp. 505-511
    • Tadokoro, C.E.1
  • 32
    • 69549103141 scopus 로고    scopus 로고
    • Feedback control of regulatory T cell homeostasis by dendritic cells in vivo
    • Darrasse-Jeze G, et al. Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. J Exp Med 2009;206:1853-1862.
    • (2009) J Exp Med , vol.206 , pp. 1853-1862
    • Darrasse-Jeze, G.1
  • 33
    • 67650638850 scopus 로고    scopus 로고
    • Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment
    • Swee LK, Bosco N, Malissen B, Ceredig R, Rolink A. Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment. Blood 2009;113:6277-6287.
    • (2009) Blood , vol.113 , pp. 6277-6287
    • Swee, L.K.1    Bosco, N.2    Malissen, B.3    Ceredig, R.4    Rolink, A.5
  • 34
    • 78149310029 scopus 로고    scopus 로고
    • A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota
    • Chinen T, Volchkov PY, Chervonsky AV, Rudensky AY. A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota. J Exp Med 2010;207:2323-2330.
    • (2010) J Exp Med , vol.207 , pp. 2323-2330
    • Chinen, T.1    Volchkov, P.Y.2    Chervonsky, A.V.3    Rudensky, A.Y.4
  • 35
    • 33847153417 scopus 로고    scopus 로고
    • Foxp3-dependent programme of regulatory T-cell differentiation
    • Gavin MA, et al. Foxp3-dependent programme of regulatory T-cell differentiation. Nature 2007;445:771-775.
    • (2007) Nature , vol.445 , pp. 771-775
    • Gavin, M.A.1
  • 36
    • 33947600584 scopus 로고    scopus 로고
    • Regulatory T cell development in the absence of functional Foxp3
    • Lin W, et al. Regulatory T cell development in the absence of functional Foxp3. Nat Immunol 2007;8:359-368.
    • (2007) Nat Immunol , vol.8 , pp. 359-368
    • Lin, W.1
  • 37
    • 33847125247 scopus 로고    scopus 로고
    • Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
    • Wan YY, Flavell RA. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 2007;445:766-770.
    • (2007) Nature , vol.445 , pp. 766-770
    • Wan, Y.Y.1    Flavell, R.A.2
  • 38
    • 43449135305 scopus 로고    scopus 로고
    • TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function
    • Zhou L, et al. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature 2008;453:236-240.
    • (2008) Nature , vol.453 , pp. 236-240
    • Zhou, L.1
  • 39
    • 36048978911 scopus 로고    scopus 로고
    • Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
    • Hill JA, et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity 2007;27:786-800.
    • (2007) Immunity , vol.27 , pp. 786-800
    • Hill, J.A.1
  • 40
    • 33847220736 scopus 로고    scopus 로고
    • Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
    • Zheng Y, Josefowicz SZ, Kas A, Chu TT, Gavin MA, Rudensky AY. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 2007;445:936-940.
    • (2007) Nature , vol.445 , pp. 936-940
    • Zheng, Y.1    Josefowicz, S.Z.2    Kas, A.3    Chu, T.T.4    Gavin, M.A.5    Rudensky, A.Y.6
  • 41
    • 33847242598 scopus 로고    scopus 로고
    • Foxp3 occupancy and regulation of key target genes during T-cell stimulation
    • Marson A, et al. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature 2007;445:931-935.
    • (2007) Nature , vol.445 , pp. 931-935
    • Marson, A.1
  • 42
    • 34247271308 scopus 로고    scopus 로고
    • Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
    • Williams LM, Rudensky AY. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol 2007;8:277-284.
    • (2007) Nat Immunol , vol.8 , pp. 277-284
    • Williams, L.M.1    Rudensky, A.Y.2
  • 43
    • 46749138596 scopus 로고    scopus 로고
    • Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
    • Yang XO, et al. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 2008;29:44-56.
    • (2008) Immunity , vol.29 , pp. 44-56
    • Yang, X.O.1
  • 44
    • 78650124721 scopus 로고    scopus 로고
    • Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice
    • Sharma MD, et al. Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice. Immunity 2010;33:942-954.
    • (2010) Immunity , vol.33 , pp. 942-954
    • Sharma, M.D.1
  • 45
    • 60549115770 scopus 로고    scopus 로고
    • Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
    • Komatsu N, Mariotti-Ferrandiz ME, Wang Y, Malissen B, Waldmann H, Hori S. Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci USA 2009;106:1903-1908.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1903-1908
    • Komatsu, N.1    Mariotti-Ferrandiz, M.E.2    Wang, Y.3    Malissen, B.4    Waldmann, H.5    Hori, S.6
  • 46
    • 69049107358 scopus 로고    scopus 로고
    • Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
    • Zhou X, et al. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nat Immunol 2009;10:1000-1007.
    • (2009) Nat Immunol , vol.10 , pp. 1000-1007
    • Zhou, X.1
  • 47
    • 77957371028 scopus 로고    scopus 로고
    • Stability of the regulatory T cell lineage in vivo
    • Rubtsov YP, et al. Stability of the regulatory T cell lineage in vivo. Science 2010;329:1667-1671.
    • (2010) Science , vol.329 , pp. 1667-1671
    • Rubtsov, Y.P.1
  • 48
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol 2005;6:1142-1151.
    • (2005) Nat Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 49
    • 70449532980 scopus 로고    scopus 로고
    • Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
    • Oldenhove G, et al. Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity 2009;31:772-786.
    • (2009) Immunity , vol.31 , pp. 772-786
    • Oldenhove, G.1
  • 50
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Zheng Y, Josefowicz S, Chaudhry A, Peng XP, Forbush K, Rudensky AY Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 2010;463:808-812.
    • (2010) Nature , vol.463 , pp. 808-812
    • Zheng, Y.1    Josefowicz, S.2    Chaudhry, A.3    Peng, X.P.4    Forbush, K.5    Rudensky, A.Y.6
  • 51
    • 71749094333 scopus 로고    scopus 로고
    • Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome
    • Ruan Q, et al. Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome. Immunity 2009;31:932-940.
    • (2009) Immunity , vol.31 , pp. 932-940
    • Ruan, Q.1
  • 52
    • 77749245828 scopus 로고    scopus 로고
    • c-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells
    • Visekruna A, et al. c-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells. Eur J Immunol 2010;40:671-676.
    • (2010) Eur J Immunol , vol.40 , pp. 671-676
    • Visekruna, A.1
  • 53
    • 77952767221 scopus 로고    scopus 로고
    • Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development
    • Vang KB, et al. Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. J Immunol 2010;184:4074-4077.
    • (2010) J Immunol , vol.184 , pp. 4074-4077
    • Vang, K.B.1
  • 54
    • 71749088574 scopus 로고    scopus 로고
    • Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor
    • Long M, Park SG, Strickland I, Hayden MS, Ghosh S. Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. Immunity 2009;31:921-931.
    • (2009) Immunity , vol.31 , pp. 921-931
    • Long, M.1    Park, S.G.2    Strickland, I.3    Hayden, M.S.4    Ghosh, S.5
  • 55
    • 73949090725 scopus 로고    scopus 로고
    • c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells
    • Isomura I, et al. c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells. J Exp Med 2009;206:3001-3014.
    • (2009) J Exp Med , vol.206 , pp. 3001-3014
    • Isomura, I.1
  • 56
    • 77954395996 scopus 로고    scopus 로고
    • Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells
    • Harada Y, Elly C, Ying G, Paik JH, DePinho RA, Liu YC Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells. J Exp Med 2010;207:1381-1391.
    • (2010) J Exp Med , vol.207 , pp. 1381-1391
    • Harada, Y.1    Elly, C.2    Ying, G.3    Paik, J.H.4    DePinho, R.A.5    Liu, Y.C.6
  • 57
    • 77953811224 scopus 로고    scopus 로고
    • Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells
    • Ouyang W, Beckett O, Ma Q, Paik JH, DePinho RA, Li MO. Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells. Nat Immunol 2010;11:618-627.
    • (2010) Nat Immunol , vol.11 , pp. 618-627
    • Ouyang, W.1    Beckett, O.2    Ma, Q.3    Paik, J.H.4    DePinho, R.A.5    Li, M.O.6
  • 58
    • 78650085394 scopus 로고    scopus 로고
    • Foxo transcription factors control regulatory T cell development and function
    • Kerdiles YM, et al. Foxo transcription factors control regulatory T cell development and function. Immunity 2010;33:890-904.
    • (2010) Immunity , vol.33 , pp. 890-904
    • Kerdiles, Y.M.1
  • 59
    • 33845935950 scopus 로고    scopus 로고
    • IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
    • Burchill MA, Yang J, Vogtenhuber C, Blazar BR, Farrar MA. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. J Immunol 2007;178:280-290.
    • (2007) J Immunol , vol.178 , pp. 280-290
    • Burchill, M.A.1    Yang, J.2    Vogtenhuber, C.3    Blazar, B.R.4    Farrar, M.A.5
  • 60
    • 34247564147 scopus 로고    scopus 로고
    • Nonredundant roles for Stat5a/b in directly regulating Foxp3
    • Yao Z, et al. Nonredundant roles for Stat5a/b in directly regulating Foxp3. Blood 2007;109:4368-4375.
    • (2007) Blood , vol.109 , pp. 4368-4375
    • Yao, Z.1
  • 61
    • 77957724587 scopus 로고    scopus 로고
    • The Ets-1 transcription factor controls the development and function of natural regulatory T cells
    • Mouly E, et al. The Ets-1 transcription factor controls the development and function of natural regulatory T cells. J Exp Med 2010;207:2113-2125.
    • (2010) J Exp Med , vol.207 , pp. 2113-2125
    • Mouly, E.1
  • 62
    • 37849008688 scopus 로고    scopus 로고
    • Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire
    • Burchill MA, et al. Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. Immunity 2008;28:112-121.
    • (2008) Immunity , vol.28 , pp. 112-121
    • Burchill, M.A.1
  • 63
    • 37849009964 scopus 로고    scopus 로고
    • A two-step process for thymic regulatory T cell development
    • Lio CW, Hsieh CS. A two-step process for thymic regulatory T cell development. Immunity 2008;28:100-111.
    • (2008) Immunity , vol.28 , pp. 100-111
    • Lio, C.W.1    Hsieh, C.S.2
  • 64
    • 65749120321 scopus 로고    scopus 로고
    • Intraclonal competition limits the fate determination of regulatory T cells in the thymus
    • Bautista JL, et al. Intraclonal competition limits the fate determination of regulatory T cells in the thymus. Nat Immunol 2009;10:610-617.
    • (2009) Nat Immunol , vol.10 , pp. 610-617
    • Bautista, J.L.1
  • 65
    • 70350440009 scopus 로고    scopus 로고
    • TCR-dependent differentiation of thymic Foxp3+ cells is limited to small clonal sizes
    • Leung MW, Shen S, Lafaille JJ. TCR-dependent differentiation of thymic Foxp3+ cells is limited to small clonal sizes. J Exp Med 2009;206:2121-2130.
    • (2009) J Exp Med , vol.206 , pp. 2121-2130
    • Leung, M.W.1    Shen, S.2    Lafaille, J.J.3
  • 66
    • 34447265236 scopus 로고    scopus 로고
    • CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation
    • Kim HP, Leonard WJ. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. J Exp Med 2007;204:1543-1551.
    • (2007) J Exp Med , vol.204 , pp. 1543-1551
    • Kim, H.P.1    Leonard, W.J.2
  • 67
    • 33846980131 scopus 로고    scopus 로고
    • Epigenetic control of the foxp3 locus in regulatory T cells
    • Floess S, et al. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol 2007;5:e38.
    • (2007) PLoS Biol , vol.5
    • Floess, S.1
  • 68
    • 49649107703 scopus 로고    scopus 로고
    • DNA methylation controls Foxp3 gene expression
    • Polansky JK, et al. DNA methylation controls Foxp3 gene expression. Eur J Immunol 2008;38:1654-1663.
    • (2008) Eur J Immunol , vol.38 , pp. 1654-1663
    • Polansky, J.K.1
  • 69
    • 78149408519 scopus 로고    scopus 로고
    • Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells
    • Polansky JK, et al. Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells. J Mol Med 2010;88:1029-1040.
    • (2010) J Mol Med , vol.88 , pp. 1029-1040
    • Polansky, J.K.1
  • 70
    • 70350451993 scopus 로고    scopus 로고
    • Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells
    • Rudra D, Egawa T, Chong MM, Treuting P, Littman DR, Rudensky AY. Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells. Nat Immunol 2009;10:1170-1177.
    • (2009) Nat Immunol , vol.10 , pp. 1170-1177
    • Rudra, D.1    Egawa, T.2    Chong, M.M.3    Treuting, P.4    Littman, D.R.5    Rudensky, A.Y.6
  • 71
    • 70349741295 scopus 로고    scopus 로고
    • Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells
    • Kitoh A, et al. Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells. Immunity 2009;31:609-620.
    • (2009) Immunity , vol.31 , pp. 609-620
    • Kitoh, A.1
  • 72
    • 0141706718 scopus 로고    scopus 로고
    • Inheritance of Polycomb-dependent chromosomal interactions in Drosophila
    • Bantignies F, Grimaud C, Lavrov S, Gabut M, Cavalli G. Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev 2003;17:2406-2420.
    • (2003) Genes Dev , vol.17 , pp. 2406-2420
    • Bantignies, F.1    Grimaud, C.2    Lavrov, S.3    Gabut, M.4    Cavalli, G.5
  • 73
    • 0037108255 scopus 로고    scopus 로고
    • A cellular memory module conveys epigenetic inheritance of hedgehog expression during Drosophila wing imaginal disc development
    • Maurange C, Paro R. A cellular memory module conveys epigenetic inheritance of hedgehog expression during Drosophila wing imaginal disc development. Genes Dev 2002;16:2672-2683.
    • (2002) Genes Dev , vol.16 , pp. 2672-2683
    • Maurange, C.1    Paro, R.2
  • 75
    • 77957025756 scopus 로고    scopus 로고
    • Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I
    • Xu L, Kitani A, Stuelten C, McGrady G, Fuss I, Strober W. Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I. Immunity 2010;33:313-325.
    • (2010) Immunity , vol.33 , pp. 313-325
    • Xu, L.1    Kitani, A.2    Stuelten, C.3    McGrady, G.4    Fuss, I.5    Strober, W.6
  • 76
    • 34848853915 scopus 로고    scopus 로고
    • Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors
    • Cobaleda C, Jochum W, Busslinger M. Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors. Nature 2007;449:473-477.
    • (2007) Nature , vol.449 , pp. 473-477
    • Cobaleda, C.1    Jochum, W.2    Busslinger, M.3
  • 77
    • 78650178058 scopus 로고    scopus 로고
    • Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells
    • Ghosh HS, Cisse B, Bunin A, Lewis KL, Reizis B. Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells. Immunity 2010;33:905-916.
    • (2010) Immunity , vol.33 , pp. 905-916
    • Ghosh, H.S.1    Cisse, B.2    Bunin, A.3    Lewis, K.L.4    Reizis, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.