Thymus, innate immunity and autoimmune arthritis: Interplay of gene and environment

FEBS Letters

Volumn 585, Issue 23, 2011, Pages 3633-3639

  Sakaguchi, Shimon ^a,b   Tanaka, Satoshi ^b   Tanaka, Atsushi ^b   Ito, Yoshinaga ^b   Maeda, Shinji ^b   Sakaguchi, Noriko ^a   Hashimoto, Motomu ^b,c  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Animal model; Autoimmune arthritis; Innate immunity; Regulatory T cell; Rheumatoid arthritis; T cell selection; TCR signaling; ZAP 70

Indexed keywords

AUTOANTIGEN; BETA GLUCAN; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 7; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; AUTOIMMUNE DISEASE; CELL SELECTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; EFFECTOR CELL; ENVIRONMENTAL FACTOR; GENE; GENE MUTATION; HEREDITY; HUMAN; INNATE IMMUNITY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH17 CELL; THYMUS; ZAP 70 GENE;

ANIMALS; ARTHRITIS, RHEUMATOID; AUTOIMMUNITY; GENE-ENVIRONMENT INTERACTION; HUMANS; IMMUNITY, INNATE; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

ANIMALIA; MUS;

EID: 81755185452     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.10.026     Document Type: Review

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