High-throughput screening platform for engineered nanoparticle-mediated genotoxicity using cometchip technology

ACS Nano

Volumn 8, Issue 3, 2014, Pages 2118-2133

  Watson, Christa ^a   Ge, Jing ^b   Cohen, Joel ^a   Pyrgiotakis, Georgios ^a   Engelward, Bevin P ^b   Demokritou, Philip ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b USA   (United States)

Author keywords

comet; CometChip; DNA damage; engineered nanoparticles; genotoxicity; nanotoxicology

Indexed keywords

ASSAYS; CELL CULTURE; DNA; SILVER; ZINC OXIDE;

COMET; COMETCHIP; DNA DAMAGES; ENGINEERED NANOPARTICLES; GENOTOXICITIES; NANOTOXICOLOGY;

NANOPARTICLES;

FERRIC ION; FERRIC OXIDE; MUTAGENIC AGENT; NANOPARTICLE; SILICON DIOXIDE; SILVER;

ANIMAL; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; CHO CELL LINE; COMET ASSAY; CRICETULUS; DRUG EFFECT; ENGINEERING; HAMSTER; HIGH THROUGHPUT SCREENING; HUMAN; METHODOLOGY; SINGLE STRANDED DNA BREAK; STRUCTURE ACTIVITY RELATION; TIME;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CHO CELLS; COMET ASSAY; CRICETINAE; CRICETULUS; DNA BREAKS, SINGLE-STRANDED; ENGINEERING; FERRIC COMPOUNDS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MUTAGENS; NANOPARTICLES; SILICON DIOXIDE; SILVER; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 84896911744     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn404871p     Document Type: Article

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