Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity

Toxicological Sciences

Volumn 125, Issue 2, 2012, Pages 462-472

  Kao, Yi Yun ^a   Chiung, Yin Mei ^b   Chen, Yi Chun ^b   Cheng, Tsun Jen ^c   Liu, Pei Shan ^a  

^a SOOCHOW UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c Institute of Occupational Safety and Health   (Taiwan)

Author keywords

Caspase 3; Cytosolic zinc ion concentration; Mitochondria membrane potential; Mitochondrial zinc ion concentration; Zinc ion; Zinc oxide nanoparticles

Indexed keywords

CASPASE 3; LACTATE DEHYDROGENASE; NANOPARTICLE; UNCLASSIFIED DRUG; ZINC ION; ZINC OXIDE; ZINC OXIDE NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; CYTOTOXICITY; ENDOSOME; ENZYME ACTIVATION; ENZYME RELEASE; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL LINE; LEUKOCYTE; LUNG CARCINOMA; LUNG LAVAGE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; RAT;

RATTUS;

EID: 84862925782     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr319     Document Type: Article

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