Comparative study of genotoxicity and tissue distribution of nano and micron sized iron oxide in rats after acute oral treatment

Toxicology and Applied Pharmacology

Volumn 266, Issue 1, 2013, Pages 56-66

  Singh, Shailendra Pratap ^a   Rahman, M F ^a   Murty, U S N ^a   Mahboob, M ^a   Grover, Paramjit ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Biodistribution; Chromosomal aberration assay; Comet assay; Fe2O3 30nm; Fe2O3 bulk; Genotoxicity; Micronucleus test; Wistar rats

Indexed keywords

IRON OXIDE; NANOMATERIAL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSAY; ATOMIC ABSORPTION SPECTROMETRY; BONE MARROW CELL; CHROMOSOME ABERRATION; COMET ASSAY; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FECES; FEMALE; GENOTOXICITY; HEART; KIDNEY; LEUKOCYTE; LIVER; MICRONUCLEUS TEST; NANOTECHNOLOGY; NATIONAL HEALTH ORGANIZATION; NONHUMAN; RAT; SPLEEN; TISSUE DISTRIBUTION; URINE;

ADMINISTRATION, ORAL; ANIMALS; BONE MARROW CELLS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FERRIC COMPOUNDS; GASTROINTESTINAL TRACT; METAL NANOPARTICLES; RANDOM ALLOCATION; RATS; RATS, WISTAR; TIME FACTORS; TISSUE DISTRIBUTION;

RATTUS; RATTUS NORVEGICUS;

EID: 84870174971     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.10.016     Document Type: Article

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