Intraperitoneal injection of magnetic Fe3O4-nanoparticle induces hepatic and renal tissue injury via oxidative stress in mice

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 4809-4818

  Ma, Ping ^a,b   Luo, Qing ^b   Chen, Jiaoe ^a   Gan, Yaping ^a   Du, Juan ^b   Ding, Shumao ^b   Xi, Zhuge ^c   Yang, Xu ^b  

^a HUBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b CENTRAL CHINA NORMAL UNIVERSITY   (China)

^c INSTITUTE OF HEALTH AND ENVIRONMENTAL MEDICINE   (China)

Author keywords

8 hydroxy 2 deoxyguanosine; DNA protein crosslinks; Fe3O4 nanoparticles; Glutathione; Malondialdehyde; Reactive oxygen species

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DEOXYRIBONUCLEOPROTEIN; GLUTATHIONE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ADVERSE OUTCOME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; DRUG MEGADOSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENOTOXICITY; HISTOPATHOLOGY; KIDNEY INJURY; LIPID PEROXIDATION; LIVER INJURY; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PROTEIN CROSS LINKING; RISK BENEFIT ANALYSIS; SCANNING ELECTRON MICROSCOPY;

ACUTE KIDNEY INJURY; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; INJECTIONS, INTRAPERITONEAL; MAGNETITE NANOPARTICLES; MALE; MICE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

MUS;

EID: 84870356283     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S34349     Document Type: Article

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