Single-cell microarray enables high-throughput evaluation of DNA double-strand breaks and DNA repair inhibitors

Cell Cycle

Volumn 12, Issue 6, 2013, Pages 907-915

  Weingeist, David M ^a   Ge, Jing ^a   Wood, David K ^b   Mutamba, James T ^a   Huang, Qiuying ^b   Rowland, Elizabeth A ^a   Yaffe, Michael B ^a,b,c   Floyd, Scott ^b,c   Engelward, Bevin P ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

DNA double strand breaks; DNA repair; DNA PK inhibitors; High throughput; Microarray; Neutral comet assay; Neutral single cell electrophoresis assay; Non homologous end joining

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; COMET ASSAY; CONCENTRATION RESPONSE; DNA DETERMINATION; DNA END JOINING REPAIR; DNA MICROARRAY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; HIGH THROUGHPUT SCREENING; MAMMAL CELL; MORPHOLOGY; NONHUMAN; PREDICTIVE VALUE; RADIATION DOSE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS;

EID: 84875179758     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.23880     Document Type: Article

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