Cerium dioxide nanoparticles induce apoptosis and autophagy in human peripheral blood monocytes

ACS Nano

Volumn 6, Issue 7, 2012, Pages 5820-5829

  Hussain, Salik ^a   Al Nsour, Faris ^a   Rice, Annette B ^a   Marshburn, Jamie ^a   Yingling, Brenda ^a   Ji, Zhaoxia ^b   Zink, Jeffrey I ^b   Walker, Nigel J ^a   Garantziotis, Stavros ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

apoptosis; autophagy; cerium dioxide ceria; monocytes; nanoparticle; toxicity; ultrafine

Indexed keywords

APOPTOSIS-INDUCING FACTORS; AUTOPHAGY; CASPASE ACTIVATION; CELL INJURY; CELL VIABILITY; CERIUM DIOXIDES; CYTOTOXIC EFFECTS; DNA FRAGMENTATION; HEALTHY HUMANS; HUMAN CELLS; HUMAN MONOCYTES; HUMAN PERIPHERAL BLOOD; INDUSTRIAL USE; LOW DOSE; MECHANISTIC DATA; MITOCHONDRIAL DAMAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MONOCYTES; OVER-EXPRESSION; PHARMACOLOGICAL INHIBITION; REACTIVE OXYGEN SPECIES; THERAPEUTIC APPLICATION; TRANSMISSION ELECTRON MICROSCOPY TEM; TUMOR SUPPRESSOR PROTEINS; ULTRAFINE; ZETA POTENTIAL ANALYSIS;

BLOOD; CERIUM; CYTOTOXICITY; INDUSTRIAL APPLICATIONS; MITOCHONDRIA; NANOPARTICLES; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

CELL DEATH;

BAX PROTEIN, HUMAN; CERIC OXIDE; CERIUM; METAL NANOPARTICLE; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TP53 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; AUTOPHAGY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; IN VITRO STUDY; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MONOCYTE; NANOTECHNOLOGY; PATHOLOGY; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

APOPTOSIS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; CERIUM; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; METAL NANOPARTICLES; MICROSCOPY, ELECTRON, TRANSMISSION; MONOCYTES; NANOTECHNOLOGY; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84864194308     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn302235u     Document Type: Article

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