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Volumn 7, Issue 12, 2013, Pages 10621-10635

Quantification of ZnO Nanoparticle Uptake, Distribution, and Dissolution within Individual Human Macrophages

Author keywords

cellular uptake; metallomics; nanoparticle solubility; X ray fluorescence microscopy; ZnO nanoparticles

Indexed keywords

CELLULAR UPTAKE; CYTOTOXIC RESPONSE; HUMAN MACROPHAGES; METAL OXIDE NANOPARTICLES; METALLOMICS; X RAY FLUORESCENCE; X-RAY FLUORESCENCE MICROSCOPY; ZNO NANOPARTICLES;

EID: 84891369071     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn403118u     Document Type: Article
Times cited : (103)

References (93)
  • 2
    • 84866179295 scopus 로고    scopus 로고
    • Ecotoxicity of Manufactured ZnO Nanoparticles - A Review
    • Ma, H.; Williams, P. L.; Diamond, S. A. Ecotoxicity of Manufactured ZnO Nanoparticles-A Review Environ. Pollut. 2013, 172, 76-85
    • (2013) Environ. Pollut. , vol.172 , pp. 76-85
    • Ma, H.1    Williams, P.L.2    Diamond, S.A.3
  • 3
    • 31944451232 scopus 로고    scopus 로고
    • Toxic Potential of Materials at the Nanolevel
    • Nel, A.; Xia, T.; Mädler, L.; Li, N. Toxic Potential of Materials at the Nanolevel Science 2006, 311, 622-627
    • (2006) Science , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Mädler, L.3    Li, N.4
  • 4
    • 78650509723 scopus 로고    scopus 로고
    • Role of the Dissolved Zinc Ion and Reactive Oxygen Species in Cytotoxicity of ZnO Nanoparticles
    • Song, W.; Zhang, J.; Guo, J.; Zhang, J.; Ding, F.; Li, L.; Sun, Z. Role of the Dissolved Zinc Ion and Reactive Oxygen Species in Cytotoxicity of ZnO Nanoparticles Toxicol. Lett. 2010, 199, 389-397
    • (2010) Toxicol. Lett. , vol.199 , pp. 389-397
    • Song, W.1    Zhang, J.2    Guo, J.3    Zhang, J.4    Ding, F.5    Li, L.6    Sun, Z.7
  • 8
    • 80052505577 scopus 로고    scopus 로고
    • Safety Evaluation of Sunscreen Formulations Containing Titanium Dioxide and Zinc Oxide Nanoparticles in UVB Sunburned Skin: An in Vitro and in Vivo Study
    • Monteiro-Riviere, N. A.; Wiench, K.; Landsiedel, R.; Schulte, S.; Inman, A. O.; Riviere, J. E. Safety Evaluation of Sunscreen Formulations Containing Titanium Dioxide and Zinc Oxide Nanoparticles in UVB Sunburned Skin: An In Vitro and In Vivo Study Toxicol. Sci. 2011, 123, 264-280
    • (2011) Toxicol. Sci. , vol.123 , pp. 264-280
    • Monteiro-Riviere, N.A.1    Wiench, K.2    Landsiedel, R.3    Schulte, S.4    Inman, A.O.5    Riviere, J.E.6
  • 10
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the Full Spectrum of Macrophage Activation
    • Mosser, D. M.; Edwards, J. P. Exploring the Full Spectrum of Macrophage Activation Nat. Rev. Immunol. 2008, 8, 958-969
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 11
    • 84867487858 scopus 로고    scopus 로고
    • Independent Cytotoxic and Inflammatory Responses to Zinc Oxide Nanoparticles in Human Monocytes and Macrophages
    • Feltis, B. N.; O'Keefe, S. J.; Harford, A. J.; Piva, T. J.; Turney, T. W.; Wright, P. F. A. Independent Cytotoxic and Inflammatory Responses to Zinc Oxide Nanoparticles in Human Monocytes and Macrophages Nanotoxicology 2012, 6, 757-765
    • (2012) Nanotoxicology , vol.6 , pp. 757-765
    • Feltis, B.N.1    O'Keefe, S.J.2    Harford, A.J.3    Piva, T.J.4    Turney, T.W.5    Wright, P.F.A.6
  • 12
    • 79957676879 scopus 로고    scopus 로고
    • Cytotoxicity and Uptake of Zinc Oxide Nanoparticles Leading to Enhanced Inflammatory Cytokines Levels in Murine Macrophages: Comparison with Bulk Zinc Oxide
    • Roy, R.; Tripathi, A.; Das, M.; Dwivedi, P. D. Cytotoxicity and Uptake of Zinc Oxide Nanoparticles Leading to Enhanced Inflammatory Cytokines Levels in Murine Macrophages: Comparison with Bulk Zinc Oxide J. Biomed. Nanotechnol. 2011, 7, 110-111
    • (2011) J. Biomed. Nanotechnol. , vol.7 , pp. 110-111
    • Roy, R.1    Tripathi, A.2    Das, M.3    Dwivedi, P.D.4
  • 13
    • 84865129488 scopus 로고    scopus 로고
    • Zinc Oxide Nanoparticles Induce Oxidative DNA Damage and ROS-Triggered Mitochondria Mediated Apoptosis in Human Liver Cells (HepG2)
    • Sharma, V.; Anderson, D.; Dhawan, A. Zinc Oxide Nanoparticles Induce Oxidative DNA Damage and ROS-Triggered Mitochondria Mediated Apoptosis in Human Liver Cells (HepG2) Apoptosis 2012, 17, 852-870
    • (2012) Apoptosis , vol.17 , pp. 852-870
    • Sharma, V.1    Anderson, D.2    Dhawan, A.3
  • 14
    • 84862330295 scopus 로고    scopus 로고
    • Zinc Oxide Nanoparticles Selectively Induce Apoptosis in Human Cancer Cells Through Reactive Oxygen Species
    • Javed Akhtar, M.; Ahamed, M.; Sudhir, K.; Majeed Khan, M. A.; Ahmad, J.; Alrokayan, S. A. Zinc Oxide Nanoparticles Selectively Induce Apoptosis in Human Cancer Cells Through Reactive Oxygen Species Int. J. Nanomed. 2012, 7, 845-857
    • (2012) Int. J. Nanomed. , vol.7 , pp. 845-857
    • Javed Akhtar, M.1    Ahamed, M.2    Sudhir, K.3    Majeed Khan, M.A.4    Ahmad, J.5    Alrokayan, S.A.6
  • 15
    • 84862891546 scopus 로고    scopus 로고
    • The Fate of ZnO Nanoparticles Administered to Human Bronchial Epithelial Cells
    • Gilbert, B.; Fakra, S. C.; Xia, T.; Pokhrel, S.; Mädler, L.; Nel, A. E. The Fate of ZnO Nanoparticles Administered to Human Bronchial Epithelial Cells ACS Nano 2012, 6, 4921-4930
    • (2012) ACS Nano , vol.6 , pp. 4921-4930
    • Gilbert, B.1    Fakra, S.C.2    Xia, T.3    Pokhrel, S.4    Mädler, L.5    Nel, A.E.6
  • 16
    • 56049106549 scopus 로고    scopus 로고
    • Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties
    • Xia, T.; Kovochich, M.; Liong, M.; Mädler, L.; Gilbert, B.; Shi, H.; Yeh, J. I.; Zink, J. I.; Nel, A. E. Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties ACS Nano 2008, 2, 2121-2134
    • (2008) ACS Nano , vol.2 , pp. 2121-2134
    • Xia, T.1    Kovochich, M.2    Liong, M.3    Mädler, L.4    Gilbert, B.5    Shi, H.6    Yeh, J.I.7    Zink, J.I.8    Nel, A.E.9
  • 18
    • 84862908796 scopus 로고    scopus 로고
    • Dissolution of ZnO Nanoparticles at Circumneutral pH: A Study of Size Effects in the Presence and Absence of Citric Acid
    • Mudunkotuwa, I. A.; Rupasinghe, T.; Wu, C.-M.; Grassian, V. H. Dissolution of ZnO Nanoparticles at Circumneutral pH: A Study of Size Effects in the Presence and Absence of Citric Acid Langmuir 2011, 28, 396-403
    • (2011) Langmuir , vol.28 , pp. 396-403
    • Mudunkotuwa, I.A.1    Rupasinghe, T.2    Wu, C.-M.3    Grassian, V.H.4
  • 20
    • 84865781067 scopus 로고    scopus 로고
    • Palladium Nanoparticles as the Modifier for the Determination of Zn, As, Cd, Sb, Hg and Pb in Biological Samples by Ultrasonic Slurry Sampling Electrothermal Vaporization Inductively Coupled Plasma Mass Spectrometry
    • Yi, Y.-Z.; Jiang, S.-J.; Sahayam, A. C. Palladium Nanoparticles as the Modifier for the Determination of Zn, As, Cd, Sb, Hg and Pb in Biological Samples by Ultrasonic Slurry Sampling Electrothermal Vaporization Inductively Coupled Plasma Mass Spectrometry J. Anal. At. Spectrom. 2012, 27, 426-431
    • (2012) J. Anal. At. Spectrom. , vol.27 , pp. 426-431
    • Yi, Y.-Z.1    Jiang, S.-J.2    Sahayam, A.C.3
  • 21
    • 84865170415 scopus 로고    scopus 로고
    • Imaging Mass Spectrometry of Thin Tissue Sections: A Decade of Collective Efforts
    • Chaurand, P. Imaging Mass Spectrometry of Thin Tissue Sections: A Decade of Collective Efforts J. Proteomics 2012, 75, 4883-4892
    • (2012) J. Proteomics , vol.75 , pp. 4883-4892
    • Chaurand, P.1
  • 22
    • 84869465644 scopus 로고    scopus 로고
    • Quantitative Imaging of Gold and Silver Nanoparticles in Single Eukaryotic Cells by Laser Ablation ICP-MS
    • Drescher, D.; Giesen, C.; Traub, H.; Panne, U.; Kneipp, J.; Jakubowski, N. Quantitative Imaging of Gold and Silver Nanoparticles in Single Eukaryotic Cells by Laser Ablation ICP-MS Anal. Chem. 2012, 84, 9684-9688
    • (2012) Anal. Chem. , vol.84 , pp. 9684-9688
    • Drescher, D.1    Giesen, C.2    Traub, H.3    Panne, U.4    Kneipp, J.5    Jakubowski, N.6
  • 23
    • 79955804385 scopus 로고    scopus 로고
    • SEM X-ray Microanalysis of Nanoparticles Present in Tissue or Cultured Cell Thin Sections
    • In; McNeil, S. E. Humana Press: New York
    • Zheng, J.; Nagashima, K.; Parmiter, D.; Cruz, J.; Patri, A. SEM X-ray Microanalysis of Nanoparticles Present in Tissue or Cultured Cell Thin Sections. In Characterization of Nanoparticles Intended for Drug Delivery; McNeil, S. E., Ed.; Humana Press: New York, 2011; Vol. 697, pp 93-99.
    • (2011) Characterization of Nanoparticles Intended for Drug Delivery , vol.697 , pp. 93-99
    • Zheng, J.1    Nagashima, K.2    Parmiter, D.3    Cruz, J.4    Patri, A.5
  • 24
    • 34548623442 scopus 로고    scopus 로고
    • Three-Dimensional Elemental Mapping of Phosphorus by Quantitative Electron Spectroscopic Tomography (QuEST)
    • Aronova, M. A.; Kim, Y. C.; Harmon, R.; Sousa, A. A.; Zhang, G.; Leapman, R. D. Three-Dimensional Elemental Mapping of Phosphorus by Quantitative Electron Spectroscopic Tomography (QuEST) J. Struct. Biol. 2007, 160, 35-48
    • (2007) J. Struct. Biol. , vol.160 , pp. 35-48
    • Aronova, M.A.1    Kim, Y.C.2    Harmon, R.3    Sousa, A.A.4    Zhang, G.5    Leapman, R.D.6
  • 26
    • 39549089076 scopus 로고    scopus 로고
    • Comparison of NEXAFS Microscopy and TEM-EELS for Studies of Soft Matter
    • Hitchcock, A. P.; Dynes, J. J.; Johansson, G.; Wang, J.; Botton, G. Comparison of NEXAFS Microscopy and TEM-EELS for Studies of Soft Matter Micron 2008, 39, 311-319
    • (2008) Micron , vol.39 , pp. 311-319
    • Hitchcock, A.P.1    Dynes, J.J.2    Johansson, G.3    Wang, J.4    Botton, G.5
  • 27
    • 84874406895 scopus 로고    scopus 로고
    • Imaging Interactions of Metal Oxide Nanoparticles with Macrophage Cells by Ultra-High Resolution Scanning Electron Microscopy Techniques
    • Plascencia-Villa, G.; Starr, C. R.; Armstrong, L. S.; Ponce, A.; Jose-Yacaman, M. Imaging Interactions of Metal Oxide Nanoparticles with Macrophage Cells by Ultra-High Resolution Scanning Electron Microscopy Techniques Integr. Biol. 2012, 4, 1358-1366
    • (2012) Integr. Biol. , vol.4 , pp. 1358-1366
    • Plascencia-Villa, G.1    Starr, C.R.2    Armstrong, L.S.3    Ponce, A.4    Jose-Yacaman, M.5
  • 28
    • 84864310728 scopus 로고    scopus 로고
    • Visualizing Metal Ions in Cells: An Overview of Analytical Techniques, Approaches, and Probes
    • Dean, K. M.; Qin, Y.; Palmer, A. E. Visualizing Metal Ions in Cells: An Overview of Analytical Techniques, Approaches, and Probes Biochim. Biophys. Acta, Mol. Cell Res. 2012, 1823, 1406-1415
    • (2012) Biochim. Biophys. Acta, Mol. Cell Res. , vol.1823 , pp. 1406-1415
    • Dean, K.M.1    Qin, Y.2    Palmer, A.E.3
  • 29
    • 84882373300 scopus 로고    scopus 로고
    • Fluorophore-Metal Nanoparticle Interactions and Their Applications in Biosensing
    • In; Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim
    • Klar, T. A.; Feldmann, J. Fluorophore-Metal Nanoparticle Interactions and Their Applications in Biosensing. In Complex-Shaped Metal Nanoparticles; Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim, 2012; pp 395-427.
    • (2012) Complex-Shaped Metal Nanoparticles , pp. 395-427
    • Klar, T.A.1    Feldmann, J.2
  • 30
    • 84864449619 scopus 로고    scopus 로고
    • The Challenges of Using a Copper Fluorescent Sensor (CS1) to Track Intracellular Distributions of Copper in Neuronal and Glial Cells
    • Price, K. A.; Hickey, J. L.; Xiao, Z.; Wedd, A. G.; James, S. A.; Liddell, J. R.; Crouch, P. J.; White, A. R.; Donnelly, P. S. The Challenges of Using a Copper Fluorescent Sensor (CS1) to Track Intracellular Distributions of Copper in Neuronal and Glial Cells Chem. Sci. 2012, 3, 2748-2759
    • (2012) Chem. Sci. , vol.3 , pp. 2748-2759
    • Price, K.A.1    Hickey, J.L.2    Xiao, Z.3    Wedd, A.G.4    James, S.A.5    Liddell, J.R.6    Crouch, P.J.7    White, A.R.8    Donnelly, P.S.9
  • 31
    • 77957914199 scopus 로고    scopus 로고
    • Loss of Pluripotency in Human Embryonic Stem Cells Directly Correlates with an Increase in Nuclear Zinc
    • Wolford, J. L.; Chishti, Y.; Jin, Q.; Ward, J.; Chen, L.; Vogt, S.; Finney, L. Loss of Pluripotency in Human Embryonic Stem Cells Directly Correlates with an Increase in Nuclear Zinc PLoS One 2010, 5, e12308
    • (2010) PLoS One , vol.5 , pp. 12308
    • Wolford, J.L.1    Chishti, Y.2    Jin, Q.3    Ward, J.4    Chen, L.5    Vogt, S.6    Finney, L.7
  • 33
    • 33744967290 scopus 로고    scopus 로고
    • Correlative μxRF and Optical Immunofluorescence Microscopy of Adherent Cells Labeled with Ultrasmall Gold Particles
    • McRae, R.; Lai, B.; Vogt, S.; Fahrni, C. J. Correlative μXRF and Optical Immunofluorescence Microscopy of Adherent Cells Labeled with Ultrasmall Gold Particles J. Struct. Biol. 2006, 155, 22-29
    • (2006) J. Struct. Biol. , vol.155 , pp. 22-29
    • McRae, R.1    Lai, B.2    Vogt, S.3    Fahrni, C.J.4
  • 34
    • 84880895826 scopus 로고    scopus 로고
    • A Detailed Study of Gold-Nanoparticle Loaded Cells Using X-ray Based Techniques for cell-Tracking Applications with Single-Cell Sensitivity
    • Astolfo, A.; Arfelli, F.; Schultke, E.; James, S. A.; Mancini, L.; Menk, R.-H. A Detailed Study of Gold-Nanoparticle Loaded Cells Using X-ray Based Techniques for cell-Tracking Applications with Single-Cell Sensitivity Nanoscale 2013, 5, 3337-3345
    • (2013) Nanoscale , vol.5 , pp. 3337-3345
    • Astolfo, A.1    Arfelli, F.2    Schultke, E.3    James, S.A.4    Mancini, L.5    Menk, R.-H.6
  • 35
    • 84857828366 scopus 로고    scopus 로고
    • Caenorhabditis elegans Maintains Highly Compartmentalized Cellular Distribution of Metals and Steep Concentration Gradients of Manganese
    • McColl, G.; James, S. A.; Mayo, S.; Howard, D. L.; Ryan, C. G.; Kirkham, R.; Moorhead, G. F.; Paterson, D.; de Jonge, M. D.; Bush, A. I. Caenorhabditis elegans Maintains Highly Compartmentalized Cellular Distribution of Metals and Steep Concentration Gradients of Manganese PLoS One 2012, 7, e32685
    • (2012) PLoS One , vol.7 , pp. 32685
    • McColl, G.1    James, S.A.2    Mayo, S.3    Howard, D.L.4    Ryan, C.G.5    Kirkham, R.6    Moorhead, G.F.7    Paterson, D.8    De Jonge, M.D.9    Bush, A.I.10
  • 36
  • 37
    • 79951872356 scopus 로고    scopus 로고
    • Decreased Dissolution of ZnO by Iron Doping Yields Nanoparticles with Reduced Toxicity in the Rodent Lung and Zebrafish Embryos
    • Xia, T.; Zhao, Y.; Sager, T.; George, S.; Pokhrel, S.; Li, N.; Schoenfeld, D.; Meng, H.; Lin, S.; Wang, X. et al. Decreased Dissolution of ZnO by Iron Doping Yields Nanoparticles with Reduced Toxicity in the Rodent Lung and Zebrafish Embryos ACS Nano 2011, 5, 1223-1235
    • (2011) ACS Nano , vol.5 , pp. 1223-1235
    • Xia, T.1    Zhao, Y.2    Sager, T.3    George, S.4    Pokhrel, S.5    Li, N.6    Schoenfeld, D.7    Meng, H.8    Lin, S.9    Wang, X.10
  • 39
    • 84856597458 scopus 로고    scopus 로고
    • Co-Doped ZnO Nanopowders: Location of Cobalt and Reduction in Photocatalytic Activity
    • He, R.; Hocking, R. K.; Tsuzuki, T. Co-Doped ZnO Nanopowders: Location of Cobalt and Reduction in Photocatalytic Activity Mater. Chem. Phys. 2012, 132, 1035-1040
    • (2012) Mater. Chem. Phys. , vol.132 , pp. 1035-1040
    • He, R.1    Hocking, R.K.2    Tsuzuki, T.3
  • 42
    • 78650725684 scopus 로고    scopus 로고
    • Effects of Cell Culture Media on the Dynamic Formation of Protein-Nanoparticle Complexes and Influence on the Cellular Response
    • Maiorano, G.; Sabella, S.; Sorce, B.; Brunetti, V.; Malvindi, M. A.; Cingolani, R.; Pompa, P. P. Effects of Cell Culture Media on the Dynamic Formation of Protein-Nanoparticle Complexes and Influence on the Cellular Response ACS Nano 2010, 4, 7481-7491
    • (2010) ACS Nano , vol.4 , pp. 7481-7491
    • Maiorano, G.1    Sabella, S.2    Sorce, B.3    Brunetti, V.4    Malvindi, M.A.5    Cingolani, R.6    Pompa, P.P.7
  • 49
  • 50
    • 2142765951 scopus 로고    scopus 로고
    • A Syntaxin 1, Gαo, and N-Type Calcium Channel Complex at a Presynaptic Nerve Terminal: Analysis by Quantitative Immunocolocalization
    • Li, Q.; Lau, A.; Morris, T. J.; Guo, L.; Fordyce, C. B.; Stanley, E. F. A Syntaxin 1, Gαo, and N-Type Calcium Channel Complex at a Presynaptic Nerve Terminal: Analysis by Quantitative Immunocolocalization J. Neurosci. 2004, 24, 4070-4081
    • (2004) J. Neurosci. , vol.24 , pp. 4070-4081
    • Li, Q.1    Lau, A.2    Morris, T.J.3    Guo, L.4    Fordyce, C.B.5    Stanley, E.F.6
  • 53
    • 0034978467 scopus 로고    scopus 로고
    • Log-Normal Distributions Across the Sciences: Keys and Clues
    • Limpert, E.; Stahel, W. A.; Abbt, M. Log-Normal Distributions Across the Sciences: Keys and Clues BioScience 2001, 51, 341-352
    • (2001) BioScience , vol.51 , pp. 341-352
    • Limpert, E.1    Stahel, W.A.2    Abbt, M.3
  • 54
    • 33644897539 scopus 로고    scopus 로고
    • Ubiquity of Log-Normal Distributions in Intra-Cellular Reaction Dynamics
    • Furusawa, C.; Suzuki, T.; Kashiwagi, A.; Yomo, T.; Kaneko, K. Ubiquity of Log-Normal Distributions in Intra-Cellular Reaction Dynamics Biophysics 2005, 1, 25-31
    • (2005) Biophysics , vol.1 , pp. 25-31
    • Furusawa, C.1    Suzuki, T.2    Kashiwagi, A.3    Yomo, T.4    Kaneko, K.5
  • 55
    • 80455145115 scopus 로고    scopus 로고
    • A Numerical Analysis Model for Interpretation of Flow Cytometric Studies of Ex Vivo Phagocytosis
    • Strom, T. S.; Anur, P.; Prislovsky, A. A Numerical Analysis Model for Interpretation of Flow Cytometric Studies of Ex Vivo Phagocytosis PLoS One 2011, 6, e26657
    • (2011) PLoS One , vol.6 , pp. 26657
    • Strom, T.S.1    Anur, P.2    Prislovsky, A.3
  • 57
    • 34347260600 scopus 로고    scopus 로고
    • Living with Noisy Genes: How Cells Function Reliably with Inherent Variability in Gene Expression
    • Maheshri, N.; O'Shea, E. K. Living with Noisy Genes: How Cells Function Reliably with Inherent Variability in Gene Expression Annu. Rev. Biophys. Biomol. Struct. 2007, 36, 413-434
    • (2007) Annu. Rev. Biophys. Biomol. Struct. , vol.36 , pp. 413-434
    • Maheshri, N.1    O'Shea, E.K.2
  • 58
    • 0004616853 scopus 로고
    • The Stability of Transition-Metal Complexes
    • Irving, H.; Williams, R. J. P. The Stability of Transition-Metal Complexes J. Chem. Soc. 1953, 0, 3192-3210
    • (1953) J. Chem. Soc. , vol.0 , pp. 3192-3210
    • Irving, H.1    Williams, R.J.P.2
  • 59
    • 78649602405 scopus 로고    scopus 로고
    • PH-Dependent Toxicity of High Aspect Ratio ZnO Nanowires in Macrophages Due to Intracellular Dissolution
    • Müller, K., H.; Kulkarni, J.; Motskin, M.; Goode, A.; Winship, P.; Skepper, J. N.; Ryan, M. P.; Porter, A. E. pH-Dependent Toxicity of High Aspect Ratio ZnO Nanowires in Macrophages Due to Intracellular Dissolution ACS Nano 2010, 4, 6767-6779
    • (2010) ACS Nano , vol.4 , pp. 6767-6779
    • Müller, K.H.1    Kulkarni, J.2    Motskin, M.3    Goode, A.4    Winship, P.5    Skepper, J.N.6    Ryan, M.P.7    Porter, A.E.8
  • 60
    • 80052575055 scopus 로고    scopus 로고
    • Rapid Dissolution of ZnO Nanocrystals in Acidic Cancer Microenvironment Leading to Preferential Apoptosis
    • Sasidharan, A.; Chandran, P.; Menon, D.; Raman, S.; Nair, S.; Koyakutty, M. Rapid Dissolution of ZnO Nanocrystals in Acidic Cancer Microenvironment Leading to Preferential Apoptosis Nanoscale 2011, 3, 3657-3669
    • (2011) Nanoscale , vol.3 , pp. 3657-3669
    • Sasidharan, A.1    Chandran, P.2    Menon, D.3    Raman, S.4    Nair, S.5    Koyakutty, M.6
  • 62
    • 84886953381 scopus 로고    scopus 로고
    • Endocytic Regulation of Alkali Metal Transport Proteins in Mammals, Yeast and Plants
    • Mulet, J.; Llopis-Torregrosa, V.; Primo, C.; Marqués, M. C.; Yenush, L. Endocytic Regulation of Alkali Metal Transport Proteins in Mammals, Yeast and Plants Curr. Genet. 2013, 1-24
    • (2013) Curr. Genet. , pp. 1-24
    • Mulet, J.1    Llopis-Torregrosa, V.2    Primo, C.3    Marqués, M.C.4    Yenush, L.5
  • 63
    • 0041940266 scopus 로고    scopus 로고
    • Iron, Manganese, and Cobalt Transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) Expressed at the Plasma Membrane
    • Forbes, J. R.; Gros, P. Iron, Manganese, and Cobalt Transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) Expressed at the Plasma Membrane Blood 2003, 102, 1884-1892
    • (2003) Blood , vol.102 , pp. 1884-1892
    • Forbes, J.R.1    Gros, P.2
  • 67
    • 84894036271 scopus 로고    scopus 로고
    • Zinc Signals and Immune Function
    • 10.1002/biof.1114
    • Haase, H.; Rink, L. Zinc Signals and Immune Function BioFactors 2013, 10.1002/biof.1114
    • (2013) BioFactors
    • Haase, H.1    Rink, L.2
  • 68
    • 33749371029 scopus 로고    scopus 로고
    • Dissolving Behavior and Stability of ZnO Wires in Biofluids: A Study on Biodegradability and Biocompatibility of ZnO Nanostructures
    • Zhou, J.; Xu, N. S.; Wang, Z. L. Dissolving Behavior and Stability of ZnO Wires in Biofluids: A Study on Biodegradability and Biocompatibility of ZnO Nanostructures Adv. Mater. 2006, 18, 2432-2435
    • (2006) Adv. Mater. , vol.18 , pp. 2432-2435
    • Zhou, J.1    Xu, N.S.2    Wang, Z.L.3
  • 71
    • 84855878885 scopus 로고    scopus 로고
    • Differential Pro-Inflammatory Effects of Metal Oxide Nanoparticles and their Soluble Ions in Vitro and i n Vivo; Zinc and Copper Nanoparticles, but Not Their Ions, Recruit Eosinophils to the Lungs
    • Cho, W.-S.; Duffin, R.; Poland, C. A.; Duschl, A.; Oostingh, G. J.; MacNee, W.; Bradley, M.; Megson, I. L.; Donaldson, K. Differential Pro-Inflammatory Effects of Metal Oxide Nanoparticles and their Soluble Ions In Vitro and I n Vivo; Zinc and Copper Nanoparticles, But Not Their Ions, Recruit Eosinophils to the Lungs Nanotoxicology 2012, 6, 22-35
    • (2012) Nanotoxicology , vol.6 , pp. 22-35
    • Cho, W.-S.1    Duffin, R.2    Poland, C.A.3    Duschl, A.4    Oostingh, G.J.5    Macnee, W.6    Bradley, M.7    Megson, I.L.8    Donaldson, K.9
  • 72
    • 74649084231 scopus 로고    scopus 로고
    • The Influences of Cell Type and ZnO Nanoparticle Size on Immune Cell Cytotoxicity and Cytokine Induction
    • Hanley, C.; Thurber, A.; Hanna, C.; Punnoose, A.; Zhang, J.; Wingett, D. The Influences of Cell Type and ZnO Nanoparticle Size on Immune Cell Cytotoxicity and Cytokine Induction Nanoscale Res. Lett. 2009, 4, 1409-1420
    • (2009) Nanoscale Res. Lett. , vol.4 , pp. 1409-1420
    • Hanley, C.1    Thurber, A.2    Hanna, C.3    Punnoose, A.4    Zhang, J.5    Wingett, D.6
  • 74
    • 0023732274 scopus 로고
    • A Site-Specific Mechanism for Free Radical Induced Biological Damage: The Essential Role of Redox-Active Transition Metals
    • Chevion, M. A Site-Specific Mechanism for Free Radical Induced Biological Damage: The Essential Role of Redox-Active Transition Metals Free Radical Biol. Med. 1988, 5, 27-37
    • (1988) Free Radical Biol. Med. , vol.5 , pp. 27-37
    • Chevion, M.1
  • 75
    • 34447106867 scopus 로고    scopus 로고
    • The Zinc/Thiolate Redox Biochemistry of Metallothionein and the Control of Zinc Ion Fluctuations in Cell Signaling
    • KreÌ̈ziel, A.; Hao, Q.; Maret, W. The Zinc/Thiolate Redox Biochemistry of Metallothionein and the Control of Zinc Ion Fluctuations in Cell Signaling Arch. Biochem. Biophys. 2007, 463, 188-200
    • (2007) Arch. Biochem. Biophys. , vol.463 , pp. 188-200
    • Kreì̈ziel, A.1    Hao, Q.2    Maret, W.3
  • 76
    • 84867534243 scopus 로고    scopus 로고
    • Susceptibility of Mitochondrial Electron-Transport Complexes to Oxidative Damage. Focus on Cytochrome C Oxidase
    • Musatov, A.; Robinson, N. C. Susceptibility of Mitochondrial Electron-Transport Complexes to Oxidative Damage. Focus on Cytochrome C Oxidase Free Radical Res. 2012, 46, 1313-1326
    • (2012) Free Radical Res. , vol.46 , pp. 1313-1326
    • Musatov, A.1    Robinson, N.C.2
  • 77
    • 84887859098 scopus 로고    scopus 로고
    • Relating Cytotoxicity, Zinc Ions, and Reactive Oxygen in ZnO Nanoparticle-Exposed Human Immune Cells
    • 10.1093/toxsci/kft187
    • Shen, C.; James, S. A.; de Jonge, M. D.; Turney, T. W.; Wright, P. F. A.; Feltis, B. N. Relating Cytotoxicity, Zinc Ions, and Reactive Oxygen in ZnO Nanoparticle-Exposed Human Immune Cells Toxicol. Sci. 2013, 10.1093/toxsci/ kft187
    • (2013) Toxicol. Sci.
    • Shen, C.1    James, S.A.2    De Jonge, M.D.3    Turney, T.W.4    Wright, P.F.A.5    Feltis, B.N.6
  • 80
    • 0021017501 scopus 로고
    • Rapid Acidification of Endocytic Vesicles Containing Asialoglycoprotein in Cells of a Human Hepatoma Line
    • Tycko, B.; Keith, C. H.; Maxfield, F. R. Rapid Acidification of Endocytic Vesicles Containing Asialoglycoprotein in Cells of a Human Hepatoma Line J. Cell Biol. 1983, 97, 1762-1776
    • (1983) J. Cell Biol. , vol.97 , pp. 1762-1776
    • Tycko, B.1    Keith, C.H.2    Maxfield, F.R.3
  • 82
    • 84883158864 scopus 로고    scopus 로고
    • Cytosolic Zinc Accumulation Contributes to Excitotoxic Oligodendroglial Death
    • Mato, S.; Sánchez-Gómez, M. V.; Bernal-Chico, A.; Matute, C. Cytosolic Zinc Accumulation Contributes to Excitotoxic Oligodendroglial Death Glia 2013, 61, 750-764
    • (2013) Glia , vol.61 , pp. 750-764
    • Mato, S.1    Sánchez-Gómez, M.V.2    Bernal-Chico, A.3    Matute, C.4
  • 84
    • 33749987490 scopus 로고    scopus 로고
    • In Vitro Studies of Copper Release from Powder Particles in Synthetic Biological Media
    • Midander, K.; Wallinder, I. O.; Leygraf, C. In Vitro Studies of Copper Release from Powder Particles in Synthetic Biological Media Environ. Pollut. 2007, 145, 51-59
    • (2007) Environ. Pollut. , vol.145 , pp. 51-59
    • Midander, K.1    Wallinder, I.O.2    Leygraf, C.3
  • 86
    • 0037687691 scopus 로고    scopus 로고
    • MAPS: A Set of Software Tools for Analysis and Visualization of 3D X-ray Fluorescence Data sets
    • Vogt, S. MAPS: A Set of Software Tools for Analysis and Visualization of 3D X-ray Fluorescence Data sets J. Phys. IV 2003, 104, 635-638
    • (2003) J. Phys. IV , vol.104 , pp. 635-638
    • Vogt, S.1
  • 87
    • 0034440686 scopus 로고    scopus 로고
    • Quantitative Trace Element Imaging Using PIXE and the Nuclear Microprobe
    • Ryan, C. G. Quantitative Trace Element Imaging Using PIXE and the Nuclear Microprobe Int. J. Imaging Syst. Technol. 2000, 11, 219-230
    • (2000) Int. J. Imaging Syst. Technol. , vol.11 , pp. 219-230
    • Ryan, C.G.1
  • 88
    • 0035388028 scopus 로고    scopus 로고
    • Developments in Dynamic Analysis for Quantitative PIXE True Elemental Imaging
    • Ryan, C. G. Developments in Dynamic Analysis for Quantitative PIXE True Elemental Imaging Nucl. Instrum. Methods Phys. Res., Sect. B 2001, 181, 170-179
    • (2001) Nucl. Instrum. Methods Phys. Res., Sect. B , vol.181 , pp. 170-179
    • Ryan, C.G.1
  • 90
    • 0025942394 scopus 로고
    • Image Averaging of Flexible Fibrous Macromolecules: The Clathrin Triskelion has an Elastic Proximal Segment
    • Kocsis, E.; Trus, B. L.; Steer, C. J.; Bisher, M. E.; Steven, A. C. Image Averaging of Flexible Fibrous Macromolecules: The Clathrin Triskelion has an Elastic Proximal Segment J. Struct. Biol. 1991, 107, 6-14
    • (1991) J. Struct. Biol. , vol.107 , pp. 6-14
    • Kocsis, E.1    Trus, B.L.2    Steer, C.J.3    Bisher, M.E.4    Steven, A.C.5
  • 91
    • 84863205849 scopus 로고    scopus 로고
    • NIH Image to ImageJ: 25 Years of Image Analysis
    • Schneider, C. A.; Rasband, W. S.; Eliceiri, K. W. NIH Image to ImageJ: 25 Years of Image Analysis Nat. Methods 2012, 9, 671-675
    • (2012) Nat. Methods , vol.9 , pp. 671-675
    • Schneider, C.A.1    Rasband, W.S.2    Eliceiri, K.W.3
  • 92
    • 33845764296 scopus 로고    scopus 로고
    • A Guided Tour into Subcellular Colocalization Analysis in Light Microscopy
    • Bolte, S.; Cordelieres, F. P. A Guided Tour into Subcellular Colocalization Analysis in Light Microscopy J. Microsc. 2006, 224, 213-232
    • (2006) J. Microsc. , vol.224 , pp. 213-232
    • Bolte, S.1    Cordelieres, F.P.2
  • 93
    • 0035041142 scopus 로고    scopus 로고
    • A Step-By-Step guide to Non-Linear Regression Analysis of Experimental Data Using a Microsoft Excel Spreadsheet
    • Brown, A. M. A Step-By-Step guide to Non-Linear Regression Analysis of Experimental Data Using a Microsoft Excel Spreadsheet Comput. Methods Programs Biomed. 2001, 65, 191-200
    • (2001) Comput. Methods Programs Biomed. , vol.65 , pp. 191-200
    • Brown, A.M.1


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