Effects of copy center particles on the lungs: A toxicological characterization using a Balb/c mouse model

Inhalation Toxicology

Volumn 25, Issue 9, 2013, Pages 498-508

  Pirela, Sandra ^a   Molina, Ramon ^a   Watson, Christa ^a   Cohen, Joel M ^a   Bello, Dhimiter ^a,b   Demokritou, Philip ^a   Brain, Joseph ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

Author keywords

Inflammation; Lung injury; Nanoparticles; Photocopiers; Printers

Indexed keywords

COLONY STIMULATING FACTOR 1; CXCL9 CHEMOKINE; EOTAXIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 3; LACTATE DEHYDROGENASE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; COPIER EMITTED PARTICLE; DOSE RESPONSE; EXPERIMENTAL DESIGN; HYDRODYNAMICS; INFLAMMATORY CELL; INHALATION; LACTATE DEHYDROGENASE BLOOD LEVEL; LEUKOCYTE DIFFERENTIAL COUNT; LIGHT SCATTERING; LUNG; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MACROPHAGE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NOSE MUCOSA; PARTICLE RADIATION; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; RADIATION EXPOSURE; RESPIRATORY EPITHELIUM; WELDING FUME; ZETA POTENTIAL;

EID: 84881438646     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2013.806614     Document Type: Article

References (52)

1. Anjilvel S, Asgharian B. (1995). A multiple-path model of particle deposition in the rat lung. Fundam Appl Toxicol 28:41-50.
2. Antonini J, Lawryk N, Murthy G, Brain J. (1999). Effect of welding fume solubility on lung macrophage viability and function in vitro. J Toxicol Environ Health A 58:343-63.
3. Antonini J, Zeidler-erdely P, Young S, et al. (2012). Systemic immune cell response in rats after pulmonary exposure to manganese-containing particles collected from welding aerosols. J Immunotoxicol 9:184-92.
4. Bai R, Zhang L, Liu Y, et al. (2010). Pulmonary responses to printer toner particles in mice after intratracheal instillation. Toxicol Lett 199:288-300.
5. Balakrishnan M, Das A. (2010). Chromosomal aberration of workers occupationally exposed to photocopy machines in Sular, South India. Int J Pharm Bio Sci 1:b304-7.
6. Barthel M, Pedan V, Hahn O, et al. (2011). Xrf-analysis of fine and ultrafine particles emitted from laser printing devices. Environ Sci Technol 45:7819-25.
7. Beck B, Brain J, Bohannon D. (1982). An in vivo hamster bioassay to assess the toxicity of particulates for the lungs. Toxicol Appl Pharmacol 66:9-29.
8. Bello D, Martin J, Santeufemio C, et al. (2012). Physicochemical and morphological characterisation of nanoparticles from photocopiers: implications for environmental health. Nanotoxicology. [Epub ahead of print]. doi: 10.3109/17435390.2012.689883.
9. Chang P, Bhavsar P, Michaeloudes C, et al. (2012). Corticosteroid insensitivity of chemokine expression in airway smooth muscle of patients with severe asthma. J Allergy Clin Immunol 130:877-85e5.
10. Chung K, Patel H, Fadlon E, et al. (1999). Induction of eotaxin expression and release from human airway smooth muscle cells by IL-1b and TNFa: effects of IL-10 and corticosteroids. Br J Pharmacol 127:1145-50.
11. Cohen J, Deloid G, Pyrgiotakis G, Demokritou P. (2012). Interactions of engineered nanomaterials in physiological media and implications for in vitro dosimetry. Nanotoxicology 7:417-31.
12. Demokritou P, Buchel R, Molina RM, et al. (2010). Development and characterization of a versatile engineered nanomaterial generation system (venges) suitable for toxicological studies. Inhal Toxicol 22: 107-16.
13. Demokritou P, Lee SJ, Ferguson ST, Koutrakis P. (2004). A compact multistage (cascade) impactor for the characterization of atmospheric' aerosols. J Aerosol Sci 35:281-99.
14. Dockery D, Arden C, Xu X, et al. (1993). An association between air pollution and mortality in six U.S. Cities. New Engl J Med 329: 1753-9.
15. Dominici F, Peng R, Bell M, et al. (2006). Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases. J Am Med Assoc 295:1127-34.
16. Gminski R, Decker K, Heinz C, et al. (2011). Genotoxic effects of three selected black toner powders and their dimethyl sulfoxide extracts in cultured human epithelial a549 lung cells in vitro. Environ Mol Mutagen 52:296-309.
17. Goud KI, Hasan Q, Balakrishna N, et al. (2004). Genotoxicity evaluation of individuals working with photocopying machines. Mutat Res-Gen Toxicol Environ Mutagen 563:151-8.
18. Jamieson L. (2012). Ink and toner cartridge use among SMBs in the United States [Online]. Photizo Group. Available from: http://photizogroup.com/wp- content/uploads/2012/09/8.31.12-U.S.-SMB-Ink-and-Toner-Cartridge-Use.pdf. [Last accessed: 17 Mar 2013].
19. Jang S, Park JW, Cha HR, et al. (2012). Silver nanoparticles modify VEGF signaling pathway and mucus hypersecretion in allergic airway inflammation. Int J Nanomed 7:1329-43.
20. Johnson P, Roth M, Tamm M, et al. (2001). Airway smooth muscle muscle proliferation is increased in asthma. Am J Respir Crit Care Med 164:474-7.
21. Khatri M, Bello D, Gaines P, et al. (2012). Nanoparticles from photocopiers induce oxidative stress and upper respiratory tract inflammation in healthy volunteers. Nanotoxicology. [Epub ahead of print].
22. Khatri M, Bello D, Pal A, et al. (2013a). Human cell line evaluation of cytotoxic, genotoxic and inflammatory responses caused by nano-particles from photocopiers. Particle Fiber Toxicol. (submitted for publication).
23. Khatri M, Bello D, Pal A, et al. (2013b). Toxicological effects of PM0.1-2.5 particles collected from a photocopy center in three human cell lines. Inhal Toxicol. In press.
24. Kleinsorge E, Erben M, Galan M, et al. (2011). Assessment of oxidative status and genotoxicity in photocopier operators: a pilot study. Biomarkers 16:642-8.
25. Konczol M, Weiss A, Gminski R, et al. (2013). Oxidative stress and inflammatory response to printer toner particles in human epithelial A549 lung cells. Toxicol Lett 216:171-80.
26. Lee C, Hsu D. (2007). Measurements of fine and ultrafine particles formation in photocopy centers in taiwan. Atmos Environ 41: 6598-609.
27. Lin G. (1994). Toxicological studies of a representative xerox reprographic toner. Int J Toxicol 18:23-34.
28. Lough G, Schauer J, Park J, et al. (2005). Emissions of metals associated with motor vehicle roadways. Environ Sci Technol 39:826-36.
29. Manikantan P, Balachandar V, Sasikala K, et al. (2010). DNA damage in workers occupationally exposed to photocopying machines in Coimbatore South India, using comet assay. The Internet J Toxicol 7.
30. Mccullagh A, Rosenthal M, Wanner A, et al. (2010). The bronchial circulation-worth a closer look: a review of the relationship between the bronchial vasculature and airway inflammation. Pediatr Pulmonol 45:1-13.
31. Mohr U, Ernst H, Roller M, Pott F. (2005). Carcinogenicity study with nineteen granular dusts in rats. Eur J Oncol 10:249-81.
32. Mohr U, Ernst H, Roller M, Pott F. (2006). Pulmonary tumor types induced in wistar rats of the so-called "19-dust study". Exp Toxicol Pathol 58:13-20.
33. Moller A, Muhle H, Creutzenberg O, et al. (2004). Biological procedures for the toxicological assessment of toner dusts. Gefahrstoffe-reinhaltung der luft 64:13-20.
34. Montiel-davalos A, Ventura-gallegos JL, Alfaro-moreno E, et al. (2012). Tio(2) nanoparticles induce dysfunction and activation of human endothelial cells. Chem Res Toxicol 25:920-30.
35. Morawska L, He C, Johnson G, et al. (2009). An investigation into the characteristics and formation mechanisms of particles originating from the operation of laser printers. Environ Sci Technol 43:1015-22.
36. Morimoto Y, Kim H, Oyabu T, et al. (2005). Negative effect of long-term inhalation of toner on formation of 8-hydroxydeoxyguanosine in dna in the lungs of rats in vivo. Inhal Toxicol 17:749-53.
37. Morimoto Y, Ogami A, Todoroki M, et al. (2010). Expression of inflammation-related cytokines following intratracheal instillation of nickel oxide nanoparticles. Nanotoxicology 4:161-76.
38. Patel D, Tamakuwala D, Solanki K, et al. (2005). A preliminary cytogenetic and hematological study of photocopying machine operators. Ind J Occupat Environ Med 9:22-5.
39. Perrone MG, Gualtieri M, Consonni V, et al. (2013). Particle size, chemical composition, seasons of the year and urban, rural or remote site origins as determinants of biological effects of particulate matter on pulmonary cells. Environ Pollut 176c:215-27.
40. Rehn B, Bruch J, Zou T, Hobusch G. (1992). Recovery of rat alveolar macrophages by bronchoalveolar lavage under normal and activated conditions. Environ Health Perspect 97:11-16.
41. Slesinski RS, Turnbull D. (2008). Chronic inhalation exposure of rats for up to 104 weeks to a non-carbon-based magnetite photocopying toner. Int J Toxicol 27:427-39.
42. Sotiriou GA, Diaz E, Long MS, et al. (2012). A novel platform for pulmonary and cardiovascular toxicological characterization of inhaled engineered nanomaterials. Nanotoxicology 6:680-90.
43. Sriram K, Lin GX, Jefferson AM, et al. (2012). Manganese accumulation in nail clippings as a biomarker of welding fume exposure and neurotoxicity. Toxicology 291:73-82.
44. Stewart C. (2007). Copying success. The orange county register.
45. Tang T, Gminski R, Konczol M, et al. (2012a). Investigations on cytotoxic and genotoxic effects of laser printer emissions in human epithelial A549 lung cells using an air/liquid exposure system. Environ Mol Mutagen 53:125-35.
46. Tang T, Hurrass J, Gminski R, Mersch-sundermann V. (2012b). Fine and ultrafine particles emitted from laser printers as indoor air contaminants in german offices. Environ Sci Pollut Res Int 19: 3840-9.
47. Taurozzi JS, Hackley VA, Wiesner MR. (2010). Ultrasonic dispersion of nanoparticles for environmental, health and safety assessment-issues and recommendations. Nanotoxicology 5:711-29.
48. Wensing M, Pinz G, Bednarek M, et al. (2006). Particle measurement of hardcopy devices. Healthy buildings conference
49. Lisboa. Yang C, Haung Y. (2008). A cross-sectional study of respiratory and irritant health symptoms in photocopier workers in Taiwan. J Toxicol Environ Health A 71:1314-17.
50. Yazdi AS, Guarda G, Riteau N, et al. (2010). Nanoparticles activate the nlr pyrin domain containing 3 (nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta. Proc Natl Acad Sci USA 107:19449-54.
51. Zeidler-erdely P, Battelli L, Salmen-muniz R, et al. (2011). Lung tumor production and tissue metal distribution after exposure to manual metal arc-stainless steel welding fume in a/j and c57bl/6j mice. J Toxicol Environ Health A 74:728-36.
52. Zhao J, Gao Z, Tian Z, et al. (2013). The biological effects of individual-level PM2.5 exposure on systemic immunity and inflammatory response in traffic policemen. Occup Environ Med 70:426-31.