메뉴 건너뛰기




Volumn 20, Issue 9, 2014, Pages 1447-1462

Hematopoietic stem cell injury induced by ionizing radiation

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN;

EID: 84896881470     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2013.5635     Document Type: Review
Times cited : (261)

References (175)
  • 2
    • 0037071386 scopus 로고    scopus 로고
    • Replicative senescence of hematopoietic stem cells during serial transplantation: Does telomere shortening play a role?
    • Allsopp RC and Weissman IL. Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role? Oncogene 21: 3270-3273, 2002.
    • (2002) Oncogene , vol.21 , pp. 3270-3273
    • Allsopp, R.C.1    Weissman, I.L.2
  • 3
    • 0037480961 scopus 로고    scopus 로고
    • Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation
    • Allsopp RC, Morin GB, DePinho R, Harley CB, and Weissman IL. Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation. Blood 102: 517-520, 2003.
    • (2003) Blood , vol.102 , pp. 517-520
    • Allsopp, R.C.1    Morin, G.B.2    Depinho, R.3    Harley, C.B.4    Weissman, I.L.5
  • 4
    • 0345636016 scopus 로고    scopus 로고
    • Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells
    • Allsopp RC, Morin GB, Horner JW, DePinho R, Harley CB, and Weissman IL. Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells. Nat Med 9: 369-371, 2003.
    • (2003) Nat Med , vol.9 , pp. 369-371
    • Allsopp, R.C.1    Morin, G.B.2    Horner, J.W.3    Depinho, R.4    Harley, C.B.5    Weissman, I.L.6
  • 5
    • 77956239280 scopus 로고    scopus 로고
    • Noninvasive assessment of lower extremity hemodynamics in individuals with diabetes mellitus
    • Andersen CA. Noninvasive assessment of lower extremity hemodynamics in individuals with diabetes mellitus. J Vasc Surg 52: 76S-80S, 2010.
    • (2010) J Vasc Surg , vol.52
    • Andersen, C.A.1
  • 6
    • 0037023528 scopus 로고    scopus 로고
    • HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
    • Antonchuk J, Sauvageau G, and Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell 109: 39-45, 2002.
    • (2002) Cell , vol.109 , pp. 39-45
    • Antonchuk, J.1    Sauvageau, G.2    Humphries, R.K.3
  • 7
    • 34547874440 scopus 로고    scopus 로고
    • Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche
    • Arai F and Suda T. Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche. Ann N Y Acad Sci 1106: 41-53, 2007.
    • (2007) Ann N y Acad Sci , vol.1106 , pp. 41-53
    • Arai, F.1    Suda, T.2
  • 8
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, Ito K, Koh GY, and Suda T. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118: 149-161, 2004.
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6    Ito, K.7    Koh, G.Y.8    Suda, T.9
  • 10
    • 79952300115 scopus 로고    scopus 로고
    • Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species
    • Aykin-Burns N, Slane BG, Liu AT, Owens KM, O'Malley MS, Smith BJ, Domann FE, and Spitz DR. Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species. Radiat Res 175: 150-158, 2011.
    • (2011) Radiat Res , vol.175 , pp. 150-158
    • Aykin-Burns, N.1    Slane, B.G.2    Liu, A.T.3    Owens, K.M.4    O'Malley, M.S.5    Smith, B.J.6    Domann, F.E.7    Spitz, D.R.8
  • 11
    • 84867483822 scopus 로고    scopus 로고
    • Ionizing radiationinduced metabolic oxidative stress and prolonged cell injury
    • Azzam EI, Jay-Gerin JP, and Pain D. Ionizing radiationinduced metabolic oxidative stress and prolonged cell injury. Cancer Lett 327: 48-60, 2012.
    • (2012) Cancer Lett , vol.327 , pp. 48-60
    • Azzam, E.I.1    Jay-Gerin, J.P.2    Pain, D.3
  • 12
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban RS, Nemoto S, and Finkel T. Mitochondria, oxidants, and aging. Cell 120: 483-495, 2005.
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 13
    • 8144230239 scopus 로고    scopus 로고
    • Maintenance and selfrenewal of long-term reconstituting hematopoietic stem cells supported by amniotic fluid
    • Barria E, Mikels A, and Haas M. Maintenance and selfrenewal of long-term reconstituting hematopoietic stem cells supported by amniotic fluid. Stem Cells Dev 13: 548-562, 2004.
    • (2004) Stem Cells Dev , vol.13 , pp. 548-562
    • Barria, E.1    Mikels, A.2    Haas, M.3
  • 15
    • 0000062301 scopus 로고
    • Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells
    • Becker AJ, Mcculloch EA, and Till JE. Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature 197: 452-454, 1963.
    • (1963) Nature , vol.197 , pp. 452-454
    • Becker, A.J.1    McCulloch, E.A.2    Till, J.E.3
  • 16
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS generating NADPH oxidases: Physiology and pathophysiology
    • Bedard K and Krause KH. The NOX family of ROS generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 87: 245-313, 2007.
    • (2007) Physiol Rev , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 17
    • 0024457281 scopus 로고
    • The radiation response and recovery of bone marrow stroma with particular reference to long-term bone marrow cultures
    • Bierkens JG, Hendry JH, and Testa NG. The radiation response and recovery of bone marrow stroma with particular reference to long-term bone marrow cultures. Eur J Haematol 43: 95-107, 1989.
    • (1989) Eur J Haematol , vol.43 , pp. 95-107
    • Bierkens, J.G.1    Hendry, J.H.2    Testa, N.G.3
  • 18
    • 0030846533 scopus 로고    scopus 로고
    • Stem cell factor and hematopoiesis
    • Broudy VC. Stem cell factor and hematopoiesis. Blood 90: 1345-1364, 1997.
    • (1997) Blood , vol.90 , pp. 1345-1364
    • Broudy, V.C.1
  • 19
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120: 513-522, 2005.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 20
    • 0034774859 scopus 로고    scopus 로고
    • Cellular senescence, cancer and aging: The telomere connection
    • Campisi J, Kim SH, Lim CS, and Rubio M. Cellular senescence, cancer and aging: the telomere connection. Exp Gerontol 36: 1619-1637, 2001.
    • (2001) Exp Gerontol , vol.36 , pp. 1619-1637
    • Campisi, J.1    Kim, S.H.2    Lim, C.S.3    Rubio, M.4
  • 21
    • 84856076520 scopus 로고    scopus 로고
    • Ionizing radiationinduced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis
    • Carbonneau CL, Despars G, Rojas-Sutterlin S, Fortin A, Le O, Hoang T, and Beausejour CM. Ionizing radiationinduced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis. Blood 119: 717-726, 2012.
    • (2012) Blood , vol.119 , pp. 717-726
    • Carbonneau, C.L.1    Despars, G.2    Rojas-Sutterlin, S.3    Fortin, A.4    Le, O.5    Hoang, T.6    Beausejour, C.M.7
  • 23
    • 53349091768 scopus 로고    scopus 로고
    • TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
    • Chen C, Liu Y, Liu R, Ikenoue T, Guan KL, Liu Y, and Zheng P. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med 205: 2397-2408, 2008.
    • (2008) J Exp Med , vol.205 , pp. 2397-2408
    • Chen, C.1    Liu, Y.2    Liu, R.3    Ikenoue, T.4    Guan, K.L.5    Liu, Y.6    Zheng, P.7
  • 24
    • 33646469353 scopus 로고    scopus 로고
    • Cutting edge: Apoptosis-regulating signal kinase 1 is required for reactive oxygen species-mediated activation of IFN regulatory factor 3 by lipopolysaccharide
    • Chiang E, Dang O, Anderson K, Matsuzawa A, Ichijo H, and David M. Cutting edge: apoptosis-regulating signal kinase 1 is required for reactive oxygen species-mediated activation of IFN regulatory factor 3 by lipopolysaccharide. J Immunol 176: 5720-5724, 2006.
    • (2006) J Immunol , vol.176 , pp. 5720-5724
    • Chiang, E.1    Dang, O.2    Anderson, K.3    Matsuzawa, A.4    Ichijo, H.5    David, M.6
  • 26
    • 0035807964 scopus 로고    scopus 로고
    • Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
    • Christensen JL and Weissman IL. Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells. Proc Natl Acad Sci U S A 98: 14541-14546, 2001.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14541-14546
    • Christensen, J.L.1    Weissman, I.L.2
  • 27
    • 33748670457 scopus 로고    scopus 로고
    • The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
    • Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, and Evan GI. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature 443: 214-217, 2006.
    • (2006) Nature , vol.443 , pp. 214-217
    • Christophorou, M.A.1    Ringshausen, I.2    Finch, A.J.3    Swigart, L.B.4    Evan, G.I.5
  • 28
    • 33947265398 scopus 로고    scopus 로고
    • Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice
    • Chute JP, Muramoto GG, Salter AB, Meadows SK, Rickman DW, Chen B, Himburg HA, and Chao NJ. Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice. Blood 109: 2365-2372, 2007.
    • (2007) Blood , vol.109 , pp. 2365-2372
    • Chute, J.P.1    Muramoto, G.G.2    Salter, A.B.3    Meadows, S.K.4    Rickman, D.W.5    Chen, B.6    Himburg, H.A.7    Chao, N.J.8
  • 30
    • 0036286183 scopus 로고    scopus 로고
    • Hematologic consequences of exposure to ionizing radiation
    • Dainiak N. Hematologic consequences of exposure to ionizing radiation. Exp Hematol 30: 513-528, 2002.
    • (2002) Exp Hematol , vol.30 , pp. 513-528
    • Dainiak, N.1
  • 31
    • 85047692887 scopus 로고    scopus 로고
    • Expansion of human SCID-repopulating cells under hypoxic conditions
    • Danet GH, Pan Y, Luongo JL, Bonnet DA, and Simon MC. Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest 112: 126-135, 2003.
    • (2003) J Clin Invest , vol.112 , pp. 126-135
    • Danet, G.H.1    Pan, Y.2    Luongo, J.L.3    Bonnet, D.A.4    Simon, M.C.5
  • 32
    • 84858987918 scopus 로고    scopus 로고
    • The glutathione disulfide mimetic NOV-002 inhibits cyclophosphamide induced hematopoietic and immune suppression by reducing oxidative stress
    • Diaz-Montero CM, Wang Y, Shao L, Feng W, Zidan AA, Pazoles CJ, Montero AJ, and Zhou D. The glutathione disulfide mimetic NOV-002 inhibits cyclophosphamide induced hematopoietic and immune suppression by reducing oxidative stress. Free Radic Biol Med 52: 1560-1568, 2012.
    • (2012) Free Radic Biol Med , vol.52 , pp. 1560-1568
    • Diaz-Montero, C.M.1    Wang, Y.2    Shao, L.3    Feng, W.4    Zidan, A.A.5    Pazoles, C.J.6    Montero, A.J.7    Zhou, D.8
  • 33
    • 84855607470 scopus 로고    scopus 로고
    • The ATM protein kinase and cellular redox signaling: Beyond the DNA damage response
    • Ditch S and Paull TT. The ATM protein kinase and cellular redox signaling: beyond the DNA damage response. Trends Biochem Sci 37: 15-22, 2012.
    • (2012) Trends Biochem Sci , vol.37 , pp. 15-22
    • Ditch, S.1    Paull, T.T.2
  • 34
    • 0032055166 scopus 로고    scopus 로고
    • Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation
    • Domen J, Gandy KL, and Weissman IL. Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 91: 2272-2282, 1998.
    • (1998) Blood , vol.91 , pp. 2272-2282
    • Domen, J.1    Gandy, K.L.2    Weissman, I.L.3
  • 38
    • 51349138695 scopus 로고    scopus 로고
    • Oxidative stress in Fanconi anemia hematopoiesis and disease progression
    • Du W, Adam Z, Rani R, Zhang X, and Pang Q. Oxidative stress in Fanconi anemia hematopoiesis and disease progression. Antioxid Redox Signal 10: 1909-1921, 2008.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1909-1921
    • Du, W.1    Adam, Z.2    Rani, R.3    Zhang, X.4    Pang, Q.5
  • 39
    • 0037012003 scopus 로고    scopus 로고
    • Hematopoietic cells and replicative senescence
    • Effros RB and Globerson A. Hematopoietic cells and replicative senescence. Exp Gerontol 37: 191-196, 2002.
    • (2002) Exp Gerontol , vol.37 , pp. 191-196
    • Effros, R.B.1    Globerson, A.2
  • 40
    • 33845739316 scopus 로고    scopus 로고
    • Increased longevity of hematopoiesis in continuous bone marrow cultures derived from NOS1 (nNOS, mtNOS) homozygous recombinant negative mice correlates with radioresistance of hematopoietic and marrow stromal cells
    • Epperly MW, Cao S, Zhang X, Franicola D, Shen H, Greenberger EE, Epperly LD, and Greenberger JS. Increased longevity of hematopoiesis in continuous bone marrow cultures derived from NOS1 (nNOS, mtNOS) homozygous recombinant negative mice correlates with radioresistance of hematopoietic and marrow stromal cells. Exp Hematol 35: 137-145, 2007.
    • (2007) Exp Hematol , vol.35 , pp. 137-145
    • Epperly, M.W.1    Cao, S.2    Zhang, X.3    Franicola, D.4    Shen, H.5    Greenberger, E.E.6    Epperly, L.D.7    Greenberger, J.S.8
  • 41
    • 28844472952 scopus 로고    scopus 로고
    • BH3-only proteins puma and bim are rate-limiting for gammaradiation-and glucocorticoid-induced apoptosis of lymphoid cells in vivo
    • Erlacher M, Michalak EM, Kelly PN, Labi V, Niederegger H, Coultas L, Adams JM, Strasser A, and Villunger A. BH3-only proteins Puma and Bim are rate-limiting for gammaradiation-and glucocorticoid-induced apoptosis of lymphoid cells in vivo. Blood 106: 4131-4138, 2005.
    • (2005) Blood , vol.106 , pp. 4131-4138
    • Erlacher, M.1    Michalak, E.M.2    Kelly, P.N.3    Labi, V.4    Niederegger, H.5    Coultas, L.6    Adams, J.M.7    Strasser, A.8    Villunger, A.9
  • 42
    • 77956858165 scopus 로고    scopus 로고
    • Ionizing radiation and hematopoietic malignancies: Altering the adaptive landscape
    • Fleenor CJ, Marusyk A, and DeGregori J. Ionizing radiation and hematopoietic malignancies: altering the adaptive landscape. Cell Cycle 9: 3005-3011, 2010.
    • (2010) Cell Cycle , vol.9 , pp. 3005-3011
    • Fleenor, C.J.1    Marusyk, A.2    Degregori, J.3
  • 43
    • 0006234768 scopus 로고
    • Cytological identification of radiation-chimaeras
    • Ford CE, Hamerton JL, Barnes DW, and Loutit JF. Cytological identification of radiation-chimaeras. Nature 177: 452-454, 1956.
    • (1956) Nature , vol.177 , pp. 452-454
    • Ford, C.E.1    Hamerton, J.L.2    Barnes, D.W.3    Loutit, J.F.4
  • 45
    • 0027163483 scopus 로고
    • Assessing permanent damage to primitive hematopoietic stem cells after chemotherapy using the competitive repopulation assay
    • Gardner RV, Lerner C, Astle CM, and Harrison DE. Assessing permanent damage to primitive hematopoietic stem cells after chemotherapy using the competitive repopulation assay. Cancer Chemother Pharmacol 32: 450-454, 1993.
    • (1993) Cancer Chemother Pharmacol , vol.32 , pp. 450-454
    • Gardner, R.V.1    Lerner, C.2    Astle, C.M.3    Harrison, D.E.4
  • 46
    • 69449088578 scopus 로고    scopus 로고
    • MAPK signaling pathways in the regulation of hematopoiesis
    • Geest CR and Coffer PJ. MAPK signaling pathways in the regulation of hematopoiesis. J Leukoc Biol 86: 237-250, 2009.
    • (2009) J Leukoc Biol , vol.86 , pp. 237-250
    • Geest, C.R.1    Coffer, P.J.2
  • 48
    • 33746802358 scopus 로고    scopus 로고
    • Redox signaling in cancer biology
    • Gius D and Spitz DR. Redox signaling in cancer biology. Antioxid Redox Signal 8: 1249-1252, 2006.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1249-1252
    • Gius, D.1    Spitz, D.R.2
  • 50
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • Goodell MA, Brose K, Paradis G, Conner AS, and Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 183: 1797-1806, 1996.
    • (1996) J Exp Med , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 53
    • 0026006714 scopus 로고
    • Toxic effects on the hematopoietic microenvironment
    • Greenberger JS. Toxic effects on the hematopoietic microenvironment. Exp Hematol 19: 1101-1109, 1991.
    • (1991) Exp Hematol , vol.19 , pp. 1101-1109
    • Greenberger, J.S.1
  • 54
    • 0346374776 scopus 로고    scopus 로고
    • Telomeres, telomerase, and hematopoietic stem cell biology
    • Greenwood MJ and Lansdorp PM. Telomeres, telomerase, and hematopoietic stem cell biology. Arch Med Res 34: 489-495, 2003.
    • (2003) Arch Med Res , vol.34 , pp. 489-495
    • Greenwood, M.J.1    Lansdorp, P.M.2
  • 56
    • 0034213902 scopus 로고    scopus 로고
    • A new four-color flow cytometric assay to detect apoptosis in lymphocyte subsets of cultured peripheral blood cells
    • Hasper HJ, Weghorst RM, Richel DJ, Meerwaldt JH, Olthuis FM, and Schenkeveld CE. A new four-color flow cytometric assay to detect apoptosis in lymphocyte subsets of cultured peripheral blood cells. Cytometry 40: 167-171, 2000.
    • (2000) Cytometry , vol.40 , pp. 167-171
    • Hasper, H.J.1    Weghorst, R.M.2    Richel, D.J.3    Meerwaldt, J.H.4    Olthuis, F.M.5    Schenkeveld, C.E.6
  • 59
    • 0017597993 scopus 로고
    • Stem cell depletion: An explanation of the late effects of cytotoxins
    • Hellman S and Botnick LE. Stem cell depletion: an explanation of the late effects of cytotoxins. Int J Radiat Oncol Biol Phys 2: 181-184, 1977.
    • (1977) Int J Radiat Oncol Biol Phys , vol.2 , pp. 181-184
    • Hellman, S.1    Botnick, L.E.2
  • 60
    • 0021845173 scopus 로고
    • The cellular basis of long-term marrow injury after irradiation
    • Hendry JH. The cellular basis of long-term marrow injury after irradiation. Radiother Oncol 3: 331-338, 1985.
    • (1985) Radiother Oncol , vol.3 , pp. 331-338
    • Hendry, J.H.1
  • 65
    • 0033760763 scopus 로고    scopus 로고
    • Effect of bcl-2 deficiency on the radiation response of clonogenic cells in small and large intestine, bone marrow and testis
    • Hoyes KP, Cai WB, Potten CS, and Hendry JH. Effect of bcl-2 deficiency on the radiation response of clonogenic cells in small and large intestine, bone marrow and testis. Int J Radiat Biol 76: 1435-1442, 2000.
    • (2000) Int J Radiat Biol , vol.76 , pp. 1435-1442
    • Hoyes, K.P.1    Cai, W.B.2    Potten, C.S.3    Hendry, J.H.4
  • 70
    • 0345932931 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway
    • Iwasa H, Han J, and Ishikawa F. Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells 8: 131-144, 2003.
    • (2003) Genes Cells , vol.8 , pp. 131-144
    • Iwasa, H.1    Han, J.2    Ishikawa, F.3
  • 71
    • 0000653216 scopus 로고
    • Evidence for a humoral factor (or factors) concerned in recovery from radiation injury: A review
    • Jacobson LO. Evidence for a humoral factor (or factors) concerned in recovery from radiation injury: a review. Cancer Res 12: 315-325, 1952.
    • (1952) Cancer Res , vol.12 , pp. 315-325
    • Jacobson, L.O.1
  • 72
    • 78651039513 scopus 로고
    • Hematopoietic responses to radiation injury
    • Jacobson LO. Hematopoietic responses to radiation injury. Annu Rev Med 7: 345-352, 1956.
    • (1956) Annu Rev Med , vol.7 , pp. 345-352
    • Jacobson, L.O.1
  • 73
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L and Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 25: 585-621, 1961.
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 75
    • 33745551781 scopus 로고    scopus 로고
    • Ionizing radiation induces apoptosis and inhibits neuronal differentiation in rat neural stem cells via the c-Jun NH2-terminal kinase (JNK) pathway
    • Kanzawa T, Iwado E, Aoki H, Iwamaru A, Hollingsworth EF, Sawaya R, Kondo S, and Kondo Y. Ionizing radiation induces apoptosis and inhibits neuronal differentiation in rat neural stem cells via the c-Jun NH2-terminal kinase (JNK) pathway. Oncogene 25: 3638-3648, 2006.
    • (2006) Oncogene , vol.25 , pp. 3638-3648
    • Kanzawa, T.1    Iwado, E.2    Aoki, H.3    Iwamaru, A.4    Hollingsworth, E.F.5    Sawaya, R.6    Kondo, S.7    Kondo, Y.8
  • 76
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, and Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239-257, 1972.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 77
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • Keyse SM. Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 27: 253-261, 2008.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 78
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, and Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121: 1109-1121, 2005.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Yilmaz, O.H.4    Terhorst, C.5    Morrison, S.J.6
  • 79
    • 0142214646 scopus 로고    scopus 로고
    • Thrombopoietin stimulates Hoxb4 expression: An explanation for the favorable effects of TPO on hematopoietic stem cells
    • Kirito K, Fox N, and Kaushansky K. Thrombopoietin stimulates Hoxb4 expression: an explanation for the favorable effects of TPO on hematopoietic stem cells. Blood 102: 3172-3178, 2003.
    • (2003) Blood , vol.102 , pp. 3172-3178
    • Kirito, K.1    Fox, N.2    Kaushansky, K.3
  • 80
    • 80555148138 scopus 로고    scopus 로고
    • Ionizing radiation accelerates Drp1-dependent mitochondrial fission, which involves delayed mitochondrial reactive oxygen species production in normal human fibroblast-like cells
    • Kobashigawa S, Suzuki K, and Yamashita S. Ionizing radiation accelerates Drp1-dependent mitochondrial fission, which involves delayed mitochondrial reactive oxygen species production in normal human fibroblast-like cells. Biochem Biophys Res Commun 414: 795-800, 2011.
    • (2011) Biochem Biophys Res Commun , vol.414 , pp. 795-800
    • Kobashigawa, S.1    Suzuki, K.2    Yamashita, S.3
  • 83
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis JM and Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81: 807-869, 2001.
    • (2001) Physiol Rev , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 85
    • 34347257042 scopus 로고    scopus 로고
    • Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy
    • Lambeth JD. Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. Free Radic Biol Med 43: 332-347, 2007.
    • (2007) Free Radic Biol Med , vol.43 , pp. 332-347
    • Lambeth, J.D.1
  • 86
    • 0027285380 scopus 로고
    • P53 mutations increase resistance to ionizing radiation
    • Lee JM and Bernstein A. p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci U S A 90: 5742-5746, 1993.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 87
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J and Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423: 255-260, 2003.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 89
  • 90
    • 79957968764 scopus 로고    scopus 로고
    • Mn(III) meso-tetrakis-(Nethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression
    • Li H, Wang Y, Pazhanisamy SK, Shao L, Batinic-Haberle I, Meng A, and Zhou D. Mn(III) meso-tetrakis-(Nethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression. Free Radic Biol Med 51: 30-37, 2011.
    • (2011) Free Radic Biol Med , vol.51 , pp. 30-37
    • Li, H.1    Wang, Y.2    Pazhanisamy, S.K.3    Shao, L.4    Batinic-Haberle, I.5    Meng, A.6    Zhou, D.7
  • 91
    • 28444486367 scopus 로고    scopus 로고
    • Stem cell niche: Structure and function
    • Li L and Xie T. Stem cell niche: structure and function. Annu Rev Cell Dev Biol 21: 605-631, 2005.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 605-631
    • Li, L.1    Xie, T.2
  • 92
    • 13944273471 scopus 로고    scopus 로고
    • P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
    • Lin T, Chao C, Saito S, Mazur SJ, Murphy ME, Appella E, and Xu Y. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 7: 165-171, 2005.
    • (2005) Nat Cell Biol , vol.7 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3    Mazur, S.J.4    Murphy, M.E.5    Appella, E.6    Xu, Y.7
  • 93
    • 79961180595 scopus 로고    scopus 로고
    • P53, oxidative stress, and aging
    • Liu D and Xu Y. p53, oxidative stress, and aging. Antioxid Redox Signal 15: 1669-1678, 2011.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 1669-1678
    • Liu, D.1    Xu, Y.2
  • 95
    • 0000448725 scopus 로고
    • Modification of irradiation injury in mice and guinea pigs by bone marrow injections
    • Lorenz E, Uphoff D, Reid TR, and Shelton E. Modification of irradiation injury in mice and guinea pigs by bone marrow injections. J Natl Cancer Inst 12: 197-201, 1951.
    • (1951) J Natl Cancer Inst , vol.12 , pp. 197-201
    • Lorenz, E.1    Uphoff, D.2    Reid, T.R.3    Shelton, E.4
  • 96
    • 0242490151 scopus 로고    scopus 로고
    • Radiation-induced genomic instability and bystander effects: Inter-related nontargeted effects of exposure to ionizing radiation
    • Lorimore SA, Coates PJ, and Wright EG. Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation. Oncogene 22: 7058-7069, 2003.
    • (2003) Oncogene , vol.22 , pp. 7058-7069
    • Lorimore, S.A.1    Coates, P.J.2    Wright, E.G.3
  • 97
    • 0037309326 scopus 로고    scopus 로고
    • Tumor suppression by Ink4a-Arf: Progress and puzzles
    • Lowe SW and Sherr CJ. Tumor suppression by Ink4a-Arf: progress and puzzles. Curr Opin Genet Dev 13: 77-83, 2003.
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 77-83
    • Lowe, S.W.1    Sherr, C.J.2
  • 98
    • 0033208655 scopus 로고    scopus 로고
    • Dose-response effects of inactivated Newcastle disease vaccines: Influence of serologic assay, time after vaccination, and type of chickens
    • Maas RA, Oei HL, Venema-Kemper S, Koch G, and Bongers J. Dose-response effects of inactivated Newcastle disease vaccines: influence of serologic assay, time after vaccination, and type of chickens. Avian Dis 43: 670-677, 1999.
    • (1999) Avian Dis , vol.43 , pp. 670-677
    • Maas, R.A.1    Oei, H.L.2    Venema-Kemper, S.3    Koch, G.4    Bongers, J.5
  • 100
    • 84959796172 scopus 로고
    • Successful skin homografts after the administration of high dosage X radiation and homologous bone marrow
    • Main JM and Prehn RT. Successful skin homografts after the administration of high dosage X radiation and homologous bone marrow. J Natl Cancer Inst 15: 1023-1029, 1955.
    • (1955) J Natl Cancer Inst , vol.15 , pp. 1023-1029
    • Main, J.M.1    Prehn, R.T.2
  • 101
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis. An overview of cell death
    • Majno G and Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 146: 3-15, 1995.
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 103
    • 49349083531 scopus 로고    scopus 로고
    • Redox control of cell fate by MAP kinase: Physiological roles of ASK1-MAP kinase pathway in stress signaling
    • Matsuzawa A and Ichijo H. Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling. Biochim Biophys Acta 1780: 1325-1336, 2008.
    • (2008) Biochim Biophys Acta , vol.1780 , pp. 1325-1336
    • Matsuzawa, A.1    Ichijo, H.2
  • 105
    • 0023685196 scopus 로고
    • Permanent loss in stem cell self renewal capacity following stress to the marrow
    • Mauch P, Rosenblatt M, and Hellman S. Permanent loss in stem cell self renewal capacity following stress to the marrow. Blood 72: 1193-1196, 1988.
    • (1988) Blood , vol.72 , pp. 1193-1196
    • Mauch, P.1    Rosenblatt, M.2    Hellman, S.3
  • 106
    • 0343236268 scopus 로고
    • The radiation sensitivity of normal mouse bone marrow cells, determined by quantitative marrow transplantation into irradiated mice
    • Mcculloch EA and Till JE. The radiation sensitivity of normal mouse bone marrow cells, determined by quantitative marrow transplantation into irradiated mice. Radiat Res 13: 115-125, 1960.
    • (1960) Radiat Res , vol.13 , pp. 115-125
    • McCulloch, E.A.1    Till, J.E.2
  • 108
    • 0345528832 scopus 로고    scopus 로고
    • Ionizing radiation and busulfan inhibit murine bone marrow cell hematopoietic function via apoptosis-dependent and-independent mechanisms
    • Meng A, Wang Y, Brown SA, Van Zant G, and Zhou D. Ionizing radiation and busulfan inhibit murine bone marrow cell hematopoietic function via apoptosis-dependent and-independent mechanisms. Exp Hematol 31: 1348-1356, 2003.
    • (2003) Exp Hematol , vol.31 , pp. 1348-1356
    • Meng, A.1    Wang, Y.2    Brown, S.A.3    Van Zant, G.4    Zhou, D.5
  • 109
    • 0141482100 scopus 로고    scopus 로고
    • Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells
    • Meng A, Wang Y, Van Zant G, and Zhou D. Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells. Cancer Res 63: 5414-5419, 2003.
    • (2003) Cancer Res , vol.63 , pp. 5414-5419
    • Meng, A.1    Wang, Y.2    Van Zant, G.3    Zhou, D.4
  • 111
    • 77955912797 scopus 로고    scopus 로고
    • Apoptosis-promoted tumorigenesis: Gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death
    • Michalak EM, Vandenberg CJ, Delbridge AR, Wu L, Scott CL, Adams JM, and Strasser A. Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death. Genes Dev 24: 1608-1613, 2010.
    • (2010) Genes Dev , vol.24 , pp. 1608-1613
    • Michalak, E.M.1    Vandenberg, C.J.2    Delbridge, A.R.3    Wu, L.4    Scott, C.L.5    Adams, J.M.6    Strasser, A.7
  • 113
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, and Morrison SJ. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425: 962-967, 2003.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 114
    • 0036735783 scopus 로고    scopus 로고
    • Irradiation induces neural precursor-cell dysfunction
    • Monje ML, Mizumatsu S, Fike JR, and Palmer TD. Irradiation induces neural precursor-cell dysfunction. Nat Med 8: 955-962, 2002.
    • (2002) Nat Med , vol.8 , pp. 955-962
    • Monje, M.L.1    Mizumatsu, S.2    Fike, J.R.3    Palmer, T.D.4
  • 115
    • 0038640479 scopus 로고    scopus 로고
    • Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects
    • Morgan WF. Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiat Res 159: 581-596, 2003.
    • (2003) Radiat Res , vol.159 , pp. 581-596
    • Morgan, W.F.1
  • 119
    • 0027888222 scopus 로고
    • Hematopoietic stem cell deficit of transplanted bone marrow previously exposed to cytotoxic agents
    • Neben S, Hellman S, Montgomery M, Ferrara J, and Mauch P. Hematopoietic stem cell deficit of transplanted bone marrow previously exposed to cytotoxic agents. Exp Hematol 21: 156-162, 1993.
    • (1993) Exp Hematol , vol.21 , pp. 156-162
    • Neben, S.1    Hellman, S.2    Montgomery, M.3    Ferrara, J.4    Mauch, P.5
  • 121
    • 0000838940 scopus 로고
    • Growth and continued function of rat marrow cells in x-radiated mice
    • Nowell PC, Cole LJ, Habermeyer JG, and Roan PL. Growth and continued function of rat marrow cells in x-radiated mice. Cancer Res 16: 258-261, 1956.
    • (1956) Cancer Res , vol.16 , pp. 258-261
    • Nowell, P.C.1    Cole, L.J.2    Habermeyer, J.G.3    Roan, P.L.4
  • 122
    • 0027092050 scopus 로고
    • In vivo and in vitro stem cell function of ckit-and Sca-1-positive murine hematopoietic cells
    • Okada S, Nakauchi H, Nagayoshi K, Nishikawa S, Miura Y, and Suda T. In vivo and in vitro stem cell function of ckit-and Sca-1-positive murine hematopoietic cells. Blood 80: 3044-3050, 1992.
    • (1992) Blood , vol.80 , pp. 3044-3050
    • Okada, S.1    Nakauchi, H.2    Nagayoshi, K.3    Nishikawa, S.4    Miura, Y.5    Suda, T.6
  • 123
    • 77957020167 scopus 로고    scopus 로고
    • The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche
    • Omatsu Y, Sugiyama T, Kohara H, Kondoh G, Fujii N, Kohno K, and Nagasawa T. The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche. Immunity 33: 387-399, 2010.
    • (2010) Immunity , vol.33 , pp. 387-399
    • Omatsu, Y.1    Sugiyama, T.2    Kohara, H.3    Kondoh, G.4    Fujii, N.5    Kohno, K.6    Nagasawa, T.7
  • 124
    • 0029796633 scopus 로고    scopus 로고
    • Longterm lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
    • Osawa M, Hanada K, Hamada H, and Nakauchi H. Longterm lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273: 242-245, 1996.
    • (1996) Science , vol.273 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3    Nakauchi, H.4
  • 125
    • 80053513183 scopus 로고    scopus 로고
    • Regulation of protein tyrosine phosphatases by reversible oxidation
    • Ostman A, Frijhoff J, Sandin A, and Bohmer FD. Regulation of protein tyrosine phosphatases by reversible oxidation. J Biochem 150: 345-356, 2011.
    • (2011) J Biochem , vol.150 , pp. 345-356
    • Ostman, A.1    Frijhoff, J.2    Sandin, A.3    Bohmer, F.D.4
  • 126
    • 84862776900 scopus 로고    scopus 로고
    • Acceleration of astrocytic differentiation in neural stem cells surviving X-irradiation
    • Ozeki A, Suzuki K, Suzuki M, Ozawa H, and Yamashita S. Acceleration of astrocytic differentiation in neural stem cells surviving X-irradiation. Neuroreport 23: 290-293, 2012.
    • (2012) Neuroreport , vol.23 , pp. 290-293
    • Ozeki, A.1    Suzuki, K.2    Suzuki, M.3    Ozawa, H.4    Yamashita, S.5
  • 128
    • 62149114138 scopus 로고    scopus 로고
    • Dualspecificity phosphatases: Critical regulators with diverse cellular targets
    • Patterson KI, Brummer T, O'Brien PM, and Daly RJ. Dualspecificity phosphatases: critical regulators with diverse cellular targets. Biochem J 418: 475-489, 2009.
    • (2009) Biochem J , vol.418 , pp. 475-489
    • Patterson, K.I.1    Brummer, T.2    O'Brien, P.M.3    Daly, R.J.4
  • 129
    • 33846130574 scopus 로고    scopus 로고
    • Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species
    • Piccoli C, D'Aprile A, Ripoli M, Scrima R, Lecce L, Boffoli D, Tabilio A, and Capitanio N. Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species. Biochem Biophys Res Commun 353: 965-972, 2007.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 965-972
    • Piccoli, C.1    D'Aprile, A.2    Ripoli, M.3    Scrima, R.4    Lecce, L.5    Boffoli, D.6    Tabilio, A.7    Capitanio, N.8
  • 130
    • 22544446192 scopus 로고    scopus 로고
    • Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity
    • Piccoli C, Ria R, Scrima R, Cela O, D'Aprile A, Boffoli D, Falzetti F, Tabilio A, and Capitanio N. Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity. J Biol Chem 280: 26467-26476, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 26467-26476
    • Piccoli, C.1    Ria, R.2    Scrima, R.3    Cela, O.4    D'Aprile, A.5    Boffoli, D.6    Falzetti, F.7    Tabilio, A.8    Capitanio, N.9
  • 131
    • 0042809621 scopus 로고    scopus 로고
    • Regulation of hematopoietic stem cell self-renewal
    • Reya T. Regulation of hematopoietic stem cell self-renewal. Recent Prog Horm Res 58: 283-295, 2003.
    • (2003) Recent Prog Horm Res , vol.58 , pp. 283-295
    • Reya, T.1
  • 132
    • 0032485213 scopus 로고    scopus 로고
    • Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts
    • Robles SJ and Adami GR. Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts. Oncogene 16: 1113-1123, 1998.
    • (1998) Oncogene , vol.16 , pp. 1113-1123
    • Robles, S.J.1    Adami, G.R.2
  • 136
    • 77954087743 scopus 로고    scopus 로고
    • Role of the polycomb group gene BMI1 in normal and leukemic hematopoietic stem and progenitor cells
    • Schuringa JJ and Vellenga E. Role of the polycomb group gene BMI1 in normal and leukemic hematopoietic stem and progenitor cells. Curr Opin Hematol 17: 294-299, 2010.
    • (2010) Curr Opin Hematol , vol.17 , pp. 294-299
    • Schuringa, J.J.1    Vellenga, E.2
  • 138
    • 0035545802 scopus 로고    scopus 로고
    • Putting the stress on senescence
    • Serrano M and Blasco MA. Putting the stress on senescence. Curr Opin Cell Biol 13: 748-753, 2001.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 748-753
    • Serrano, M.1    Blasco, M.A.2
  • 140
    • 77954709903 scopus 로고    scopus 로고
    • Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation
    • Shao L, Sun Y, Zhang Z, Feng W, Gao Y, Cai Z, Wang ZZ, Look AT, and Wu WS. Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation. Blood 115: 4707-4714, 2010.
    • (2010) Blood , vol.115 , pp. 4707-4714
    • Shao, L.1    Sun, Y.2    Zhang, Z.3    Feng, W.4    Gao, Y.5    Cai, Z.6    Wang, Z.Z.7    Look, A.T.8    Wu, W.S.9
  • 141
    • 0033037541 scopus 로고    scopus 로고
    • The INK4A/ARF locus and its two gene products
    • Sharpless NE and DePinho RA. The INK4A/ARF locus and its two gene products. Curr Opin Genet Dev 9: 22-30, 1999.
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 22-30
    • Sharpless, N.E.1    Depinho, R.A.2
  • 143
    • 0009542078 scopus 로고
    • Aplasia of marrow and fatal intoxication in dogs produced by roentgen radiation of all bones
    • Shouse SS, Warren SL, and Whipple GH. II. Aplasia of marrow and fatal intoxication in dogs produced by roentgen radiation of all bones. J Exp Med 53: 421-435, 1931.
    • (1931) J Exp Med , vol.53 , pp. 421-435
    • Shouse, S.S.1    Warren, S.L.2    Whipple, G.H.I.I.3
  • 144
    • 23044461852 scopus 로고    scopus 로고
    • A limited role for p16Ink4a and p19Arf in the loss of hematopoietic stem cells during proliferative stress
    • Stepanova L and Sorrentino BP. A limited role for p16Ink4a and p19Arf in the loss of hematopoietic stem cells during proliferative stress. Blood 106: 827-832, 2005.
    • (2005) Blood , vol.106 , pp. 827-832
    • Stepanova, L.1    Sorrentino, B.P.2
  • 146
    • 0037086268 scopus 로고    scopus 로고
    • DNA damage is able to induce senescence in tumor cells in vitro and in vivo
    • Te PR, Okorokov AL, Jardine L, Cummings J, and Joel SP. DNA damage is able to induce senescence in tumor cells in vitro and in vivo. Cancer Res 62: 1876-1883, 2002.
    • (2002) Cancer Res , vol.62 , pp. 1876-1883
    • Te, P.R.1    Okorokov, A.L.2    Jardine, L.3    Cummings, J.4    Joel, S.P.5
  • 147
    • 0021908880 scopus 로고
    • Long-term bone marrow damage in experimental systems and in patients after radiation or chemotherapy
    • Testa NG, Hendry JH, and Molineux G. Long-term bone marrow damage in experimental systems and in patients after radiation or chemotherapy. Anticancer Res 5: 101-110, 1985.
    • (1985) Anticancer Res , vol.5 , pp. 101-110
    • Testa, N.G.1    Hendry, J.H.2    Molineux, G.3
  • 148
    • 84956427297 scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
    • Till JE and Mcculloch EA. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res 14: 213-222, 1961.
    • (1961) Radiat Res , vol.14 , pp. 213-222
    • Till, J.E.1    McCulloch, E.A.2
  • 150
    • 0000090270 scopus 로고
    • Mortality and skin transplantability in x-irradiated mice receiving isologous, homologous or heterologous bone marrow
    • Trentin JJ. Mortality and skin transplantability in x-irradiated mice receiving isologous, homologous or heterologous bone marrow. Proc Soc Exp Biol Med 92: 688-693, 1956.
    • (1956) Proc Soc Exp Biol Med , vol.92 , pp. 688-693
    • Trentin, J.J.1
  • 151
    • 0032530347 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor enhances bone marrow stem cell damage caused by repeated administration of cytotoxic agents
    • van Os R, Robinson S, Sheridan T, Mislow JM, Dawes D, and Mauch PM. Granulocyte colony-stimulating factor enhances bone marrow stem cell damage caused by repeated administration of cytotoxic agents. Blood 92: 1950-1956, 1998.
    • (1998) Blood , vol.92 , pp. 1950-1956
    • Van Os, R.1    Robinson, S.2    Sheridan, T.3    Mislow, J.M.4    Dawes, D.5    Mauch, P.M.6
  • 152
    • 0033929767 scopus 로고    scopus 로고
    • Radiation-induced apoptosis
    • Verheij M and Bartelink H. Radiation-induced apoptosis. Cell Tissue Res 301: 133-142, 2000.
    • (2000) Cell Tissue Res , vol.301 , pp. 133-142
    • Verheij, M.1    Bartelink, H.2
  • 154
    • 0027993402 scopus 로고
    • Growth acceleration and stem cell expansion in Dexter-type cultures by neutralization of TGF-beta
    • Waegell WO, Higley HR, Kincade PW, and Dasch JR. Growth acceleration and stem cell expansion in Dexter-type cultures by neutralization of TGF-beta. Exp Hematol 22: 1051-1057, 1994.
    • (1994) Exp Hematol , vol.22 , pp. 1051-1057
    • Waegell, W.O.1    Higley, H.R.2    Kincade, P.W.3    Dasch, J.R.4
  • 156
    • 82955239883 scopus 로고    scopus 로고
    • Inhibition of p38 MAPK attenuates ionizing radiation-induced hematopoietic cell senescence and residual bone marrow injury
    • Wang Y, Liu L, and Zhou D. Inhibition of p38 MAPK attenuates ionizing radiation-induced hematopoietic cell senescence and residual bone marrow injury. Radiat Res 176: 743-752, 2011.
    • (2011) Radiat Res , vol.176 , pp. 743-752
    • Wang, Y.1    Liu, L.2    Zhou, D.3
  • 157
    • 72649103214 scopus 로고    scopus 로고
    • Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells
    • Wang Y, Liu L, Pazhanisamy SK, Li H, Meng A, and Zhou D. Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells. Free Radic Biol Med 48: 348-356, 2010.
    • (2010) Free Radic Biol Med , vol.48 , pp. 348-356
    • Wang, Y.1    Liu, L.2    Pazhanisamy, S.K.3    Li, H.4    Meng, A.5    Zhou, D.6
  • 158
    • 33747026136 scopus 로고    scopus 로고
    • Cancer therapy-induced residual bone marrow injury-mechanisms of induction and implication for therapy
    • Wang Y, Probin V, and Zhou D. Cancer therapy-induced residual bone marrow injury-mechanisms of induction and implication for therapy. Curr Cancer Ther Rev 2: 271-279, 2006.
    • (2006) Curr Cancer Ther Rev , vol.2 , pp. 271-279
    • Wang, Y.1    Probin, V.2    Zhou, D.3
  • 159
    • 33645297174 scopus 로고    scopus 로고
    • Hematopoietic stem cell senescence and long-term bone marrow injury
    • Wang Y, Schulte BA, and Zhou D. Hematopoietic stem cell senescence and long-term bone marrow injury. Cell Cycle 5: 35-38, 2006.
    • (2006) Cell Cycle , vol.5 , pp. 35-38
    • Wang, Y.1    Schulte, B.A.2    Zhou, D.3
  • 160
    • 30144439380 scopus 로고    scopus 로고
    • Total body irradiation selectively induces murine hematopoietic stem cell senescence
    • Wang Y, Schulte BA, LaRue AC, Ogawa M, and Zhou D. Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood 107: 358-366, 2006.
    • (2006) Blood , vol.107 , pp. 358-366
    • Wang, Y.1    Schulte, B.A.2    Larue, A.C.3    Ogawa, M.4    Zhou, D.5
  • 161
    • 85025425170 scopus 로고
    • Roentgen ray intoxication: I. Unit dose over thorax negative-over abdomen lethal. Epithelium of small intestine sensitive to x-rays
    • Warren SL and Whipple GH. Roentgen ray intoxication: I. unit dose over thorax negative-over abdomen lethal. Epithelium of small intestine sensitive to x-rays. J Exp Med 35: 187-202, 1922.
    • (1922) J Exp Med , vol.35 , pp. 187-202
    • Warren, S.L.1    Whipple, G.H.2
  • 164
    • 0033152340 scopus 로고    scopus 로고
    • Biochemical and genetic control of apoptosis: Relevance to normal hematopoiesis and hematological malignancies
    • Wickremasinghe RG and Hoffbrand AV. Biochemical and genetic control of apoptosis: relevance to normal hematopoiesis and hematological malignancies. Blood 93: 3587-3600, 1999.
    • (1999) Blood , vol.93 , pp. 3587-3600
    • Wickremasinghe, R.G.1    Hoffbrand, A.V.2
  • 165
    • 71849114718 scopus 로고    scopus 로고
    • Balancing dormant and self-renewing hematopoietic stem cells
    • Wilson A, Laurenti E, and Trumpp A. Balancing dormant and self-renewing hematopoietic stem cells. Curr Opin Genet Dev 19: 461-468, 2009.
    • (2009) Curr Opin Genet Dev , vol.19 , pp. 461-468
    • Wilson, A.1    Laurenti, E.2    Trumpp, A.3
  • 169
    • 84862284114 scopus 로고    scopus 로고
    • Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint
    • Yamamori T, Yasui H, Yamazumi M, Wada Y, Nakamura Y, Nakamura H, and Inanami O. Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint. Free Radic Biol Med 53: 260-270, 2012.
    • (2012) Free Radic Biol Med , vol.53 , pp. 260-270
    • Yamamori, T.1    Yasui, H.2    Yamazumi, M.3    Wada, Y.4    Nakamura, Y.5    Nakamura, H.6    Inanami, O.7
  • 172
    • 77951753647 scopus 로고    scopus 로고
    • Deletion of puma protects hematopoietic stem cells and confers longterm survival in response to high-dose gamma-irradiation
    • Yu H, Shen H, Yuan Y, XuFeng R, Hu X, Garrison SP, Zhang L, Yu J, Zambetti GP, and Cheng T. Deletion of Puma protects hematopoietic stem cells and confers longterm survival in response to high-dose gamma-irradiation. Blood 115: 3472-3480, 2010.
    • (2010) Blood , vol.115 , pp. 3472-3480
    • Yu, H.1    Shen, H.2    Yuan, Y.3    Xufeng, R.4    Hu, X.5    Garrison, S.P.6    Zhang, L.7    Yu, J.8    Zambetti, G.P.9    Cheng, T.10
  • 174
    • 78751524972 scopus 로고    scopus 로고
    • Angiopoietin-like protein 3 supports the activity of hematopoietic stem cells in the bone marrow niche
    • Zheng J, Huynh H, Umikawa M, Silvany R, and Zhang CC. Angiopoietin-like protein 3 supports the activity of hematopoietic stem cells in the bone marrow niche. Blood 117: 470-479, 2011.
    • (2011) Blood , vol.117 , pp. 470-479
    • Zheng, J.1    Huynh, H.2    Umikawa, M.3    Silvany, R.4    Zhang, C.C.5
  • 175
    • 33947309693 scopus 로고    scopus 로고
    • P38 MAP kinase regulates stem cell apoptosis in human hematopoietic failure
    • Zhou L, Opalinska J, and Verma A. p38 MAP kinase regulates stem cell apoptosis in human hematopoietic failure. Cell Cycle 6: 534-537, 2007.
    • (2007) Cell Cycle , vol.6 , pp. 534-537
    • Zhou, L.1    Opalinska, J.2    Verma, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.