Agents that cause DNA double strand breaks lead to p16(INK4a) enrichment and the premature senescence of normal fibroblasts

Oncogene

Volumn 16, Issue 9, 1998, Pages 1113-1123

  Robles, Steven J ^a   Adami, Guy R ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Cellular senescence; DNA damage; p16(INK4a); p21; p53

Indexed keywords

BLEOMYCIN; CELL MARKER; COLLAGENASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLOPHILIN; DACTINOMYCIN; DOUBLE STRANDED DNA; PROTEIN P16; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME INDUCTION; FIBROBLAST; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; SENESCENCE; TRANSACTIVATION; TUMOR SUPPRESSOR GENE;

GOES;

EID: 0032485213     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1201862     Document Type: Article

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