The p53-deficient hemopoietic stem cells: Their resistance to radiation-apoptosis, but lasted transiently

Leukemia

Volumn 11, Issue SUPPL. 3, 1997, Pages 489-492

  Hirabayashi, Yoko ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; BLOOD DISEASE; BONE MARROW; CELL CYCLE G1 PHASE; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DNA STRAND BREAKAGE; HEMATOPOIETIC STEM CELL; HETEROZYGOTE; HOMOZYGOTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RADIATION; RADIOSENSITIVITY; SPLEEN CELL;

EID: 0030878808     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Donehower LA, et al. (1992) Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356: 215-21.
2. Harvey M, et al. (1993) Genetic background alters the spectrum of tumors that develop in p53-deficient mice. FASEB J7: 938-43.
3. Kemp CJ, et al. (1994) p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis. Nat Genet 8: 66-69
4. Kemp C. J. (1995) Hepatocarcino-genesis in p53-deficientmice. Mol Carcinog 12: 132-136.
5. Lowe S.W, et al. (1994) p53 status and the efficacy of cancer therapy in vivo. Science 266: 807-810.