N-Cadherin Expression Level Distinguishes Reserved versus Primed States of Hematopoietic Stem Cells

Cell Stem Cell

Volumn 2, Issue 4, 2008, Pages 367-379

  Haug, Jeffrey S ^a   He, Xi C ^a   Grindley, Justin C ^a   Wunderlich, Joshua P ^a   Gaudenz, Karin ^a   Ross, Jason T ^a,c   Paulson, Ariel ^a   Wagner, Kathryn P ^a   Xie, Yucai ^a   Zhu, Ruihong ^a   Yin, Tong ^a   Perry, John M ^a   Hembree, Mark J ^a   Redenbaugh, Erin P ^a   Radice, Glenn L ^b   Seidel, Christopher ^a   Li, Linheng ^a,c  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

STEMCELL

Indexed keywords

NERVE CELL ADHESION MOLECULE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL ASSAY; CELL CYCLE PROGRESSION; CELL FUNCTION; CELL ISOLATION; CELL LINEAGE; CELL MOTILITY; CELL SUBPOPULATION; CONTROLLED STUDY; GENE EXPRESSION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC SYSTEM; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SPLEEN;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BASE SEQUENCE; BIOLOGICAL MARKERS; BONE MARROW CELLS; CADHERINS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; DNA PRIMERS; FLOW CYTOMETRY; FLUOROURACIL; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELLS; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOBLASTS; PROTO-ONCOGENE PROTEINS C-KIT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPLEEN;

MUS;

EID: 41449107903     PISSN: 19345909     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stem.2008.01.017     Document Type: Article

References (40)

1. Akashi K., He X., Chen J., Iwasaki H., Niu C., Steenhard B., Zhang J., Haug J., and Li L. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood 101 (2003) 383-389
2. Arai F., Hirao A., Ohmura M., Sato H., Matsuoka S., Takubo K., Ito K., Koh G.Y., and Suda T. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118 (2004) 149-161
3. Balazs A.B., Fabian A.J., Esmon C.T., and Mulligan R.C. Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood 107 (2006) 2317-2321
4. Bronner-Fraser M., Wolf J.J., and Murray B.A. Effects of antibodies against N-cadherin and N-CAM on the cranial neural crest and neural tube. Dev. Biol. 153 (1992) 291-301
5. Calvi L.M., Adams G.B., Weibrecht K.W., Weber J.M., Olson D.P., Knight M.C., Martin R.P., Schipani E., Divieti P., Bringhurst F.R., et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425 (2003) 841-846
6. Christensen J.L., and Weissman I.L. Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells. Proc. Natl. Acad. Sci. USA 98 (2001) 14541-14546
7. Fleming W.H., Alpern E.J., Uchida N., Ikuta K., Spangrude G.J., and Weissman I.L. Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells. J. Cell Biol. 122 (1993) 897-902
8. Forsberg E.C., Prohaska S.S., Katzman S., Heffner G.C., Stuart J.M., and Weissman I.L. Differential expression of novel potential regulators in hematopoietic stem cells. PLoS Genet. 1 (2005) e28 10.1371/journal.pgen.0010028
9. Gupta R., Hong D., Iborra F., Sarno S., and Enver T. NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells. Science 316 (2007) 590-593
10. Hosokawa K., Arai F., Yoshihara H., Nakamura Y., Gomei Y., Iwasaki H., Miyamoto K., Shima H., Ito K., and Suda T. Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction. Biochem. Biophys. Res. Commun. 363 (2007) 578-583
11. Jang Y.-Y., and Sharkis S.J. A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 110 (2007) 3056-3063
12. Janowska-Wieczorek A., Marquez L.A., Dobrowsky A., Ratajczak M.Z., and Cabuhat M.L. Differential MMP and TIMP production by human marrow and peripheral blood CD34(+) cells in response to chemokines. Exp. Hematol. 28 (2000) 1274-1285
13. Kasemeier-Kulesa J.C., Bradley R., Pasquale E.B., Lefcort F., and Kulesa P.M. Eph/ephrins and N-cadherin coordinate to control the pattern of sympathetic ganglia. Development 133 (2006) 4839-4847
14. Kiel M.J., Yilmaz O.H., Iwashita T., Terhorst C., and Morrison S.J. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121 (2005) 1109-1121
15. Kiel M.J., He S., Ashkenazi R., Gentry S.N., Teta M., Kushner J.A., Jackson T.L., and Morrison S.J. Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 449 (2007) 238-242
16. Kiel M.J., Radice G.L., and Morrison S.J. Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance. Cell Stem Cell 1 (2007) 204-217
17. Kollet O., Dar A., Shivtiel S., Kalinkovich A., Lapid K., Sztainberg Y., Tesio M., Samstein R.M., Goichberg P., Spiegel A., et al. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat. Med. 12 (2006) 657-664
18. Kopp H.G., Avecilla S.T., Hooper A.T., and Rafii S. The bone marrow vascular niche: home of HSC differentiation and mobilization. Physiology (Bethesda) 20 (2005) 349-356
19. Lerner C., and Harrison D.E. 5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation. Exp. Hematol. 18 (1990) 114-118
20. Luo Y., Kostetskii I., and Radice G.L. N-cadherin is not essential for limb mesenchymal chondrogenesis. Dev. Dyn. 232 (2005) 336-344
21. Moser B., Wolf M., Walz A., and Loetscher P. Chemokines: multiple levels of leukocyte migration control. Trends Immunol. 25 (2004) 75-84
22. Muguruma Y., Yahata T., Miyatake H., Sato T., Uno T., Itoh J., Kato S., Ito M., Hotta T., and Ando K. Reconstitution of the functional human hematopoietic microenvironment derived from human mesenchymal stem cells in the murine bone marrow compartment. Blood 107 (2006) 1878-1887
23. Park I.K., Qian D., Kiel M., Becker M.W., Pihalja M., Weissman I.L., Morrison S.J., and Clarke M.F. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423 (2003) 302-305
24. Pezzato E., Dona M., Sartor L., Dell'Aica I., Benelli R., Albini A., and Garbisa S. Proteinase-3 directly activates MMP-2 and degrades gelatin and Matrigel; differential inhibition by (-)epigallocatechin-3-gallate. J. Leukoc. Biol. 74 (2003) 88-94
25. Raychaudhuri S., Stuart J.M., and Altman R.B. Principal components analysis to summarize microarray experiments: application to sporulation time series. Pac. Symp. Biocomput. (2000) 455-466
26. Roederer M. Spectral compensation for flow cytometry: visualization artifacts, limitations, and caveats. Cytometry 45 (2001) 194-205
27. Scadden D.T. The stem-cell niche as an entity of action. Nature 441 (2006) 1075-1079
28. Schofield R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4 (1978) 7-25
29. Sleutels F., Zwart R., and Barlow D.P. The non-coding Air RNA is required for silencing autosomal imprinted genes. Nature 415 (2002) 810-813
30. Song X., and Xie T. DE-cadherin-mediated cell adhesion is essential for maintaining somatic stem cells in the Drosophila ovary. Proc. Natl. Acad. Sci. USA 99 (2002) 14813-14818
31. Terskikh A.V., Miyamoto T., Chang C., Diatchenko L., and Weissman I.L. Gene expression analysis of purified hematopoietic stem cells and committed progenitors. Blood 102 (2003) 94-101
32. Tucker K.L., Meyer M., and Barde Y.-A. Neurotrophins are required for nerve growth during development. Nat. Neurosci. 4 (2001) 29-37
33. Tydell C.C., David-Fung E.-S., Moore J.E., Rowen L., Taghon T., and Rothenberg E.V. Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway. J. Immunol. 179 (2007) 421-438
34. Venezia T.A., Merchant A.A., Ramos C.A., Whitehouse N.L., Young A.S., Shaw C.A., and Goodell M.A. Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol. 2 (2004) e301 10.1371/journal.pbio.0020301
35. Walkley C.R., Olsen G.H., Dworkin S., Fabb S.A., Swann J., McArthur G.A., Westmoreland S.V., Chambon P., Scadden D.T., and Purton L.E. A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell 129 (2007) 1097-1110
36. Walkley C.R., Shea J.M., Sims N.A., Purton L.E., and Orkin S.H. Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment. Cell 129 (2007) 1081-1095
37. Wilson A., Murphy M.J., Oskarsson T., Kaloulis K., Bettess M.D., Oser G.M., Pasche A.C., Knabenhans C., Macdonald H.R., and Trumpp A. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev. 18 (2004) 2747-2763
38. Yin T., and Li L. The stem cell niches in bone. J. Clin. Invest. 116 (2006) 1195-1201
39. Zhang J., Niu C., Ye L., Huang H., He X., Tong W.G., Ross J., Haug J., Johnson T., Feng J.Q., et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425 (2003) 836-841
40. Zhang C.C., Kaba M., Ge G., Xie K., Tong W., Hug C., and Lodish H.F. Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells. Nat. Med. 12 (2006) 240-245