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Volumn 106, Issue 3, 2005, Pages 827-832

A limited role for p16Ink4a and p19Arf in the loss of hematopoietic stem cells during proliferative stress

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; PROTEIN P16INK4A; PROTEIN P19; CDKN2A PROTEIN, MOUSE; PROTEIN P14ARF;

EID: 23044461852     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-06-2242     Document Type: Article
Times cited : (68)

References (23)
  • 1
    • 8544252411 scopus 로고    scopus 로고
    • Clinical strategies for expansion of haematopoietic stem cells
    • Sorrentino BP. Clinical strategies for expansion of haematopoietic stem cells. Nat Rev Immunol. 2004;4:878-888.
    • (2004) Nat Rev Immunol , vol.4 , pp. 878-888
    • Sorrentino, B.P.1
  • 2
    • 33544460095 scopus 로고    scopus 로고
    • Hematopoietic stem cell quiescence maintained by p21cip1/waf1
    • Cheng T, Rodrigues N, Shen H, et al. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science. 2000;22:5506-5517.
    • (2000) Science , vol.22 , pp. 5506-5517
    • Cheng, T.1    Rodrigues, N.2    Shen, H.3
  • 3
    • 0033694302 scopus 로고    scopus 로고
    • Stem cell repopulation efficiency but not pool size is governed by p27(kip1)
    • Cheng T, Rodrigues N, Dombkowski D, Stier S, Scadden DT. Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat Med. 2000;6:1235-1240.
    • (2000) Nat Med , vol.6 , pp. 1235-1240
    • Cheng, T.1    Rodrigues, N.2    Dombkowski, D.3    Stier, S.4    Scadden, D.T.5
  • 4
    • 2342601849 scopus 로고    scopus 로고
    • In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
    • Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol. 2004;6:436-442.
    • (2004) Nat Cell Biol , vol.6 , pp. 436-442
    • Yuan, Y.1    Shen, H.2    Franklin, D.S.3    Scadden, D.T.4    Cheng, T.5
  • 5
    • 0037480961 scopus 로고    scopus 로고
    • Telomerase is required to slow telomere shortening and extend replicative lifespan of HSC during serial transplantation
    • Allsopp RC, Morin GB, DePinho R, Harley CB, Weissman IL. Telomerase is required to slow telomere shortening and extend replicative lifespan of HSC during serial transplantation. Blood. 2003; 102:517-520.
    • (2003) Blood , vol.102 , pp. 517-520
    • Allsopp, R.C.1    Morin, G.B.2    DePinho, R.3    Harley, C.B.4    Weissman, I.L.5
  • 6
    • 0345636016 scopus 로고    scopus 로고
    • Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells
    • Allsopp RC, Morin GB, Horner JW, et al. Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells. Nat Med. 2003;9:369-371.
    • (2003) Nat Med , vol.9 , pp. 369-371
    • Allsopp, R.C.1    Morin, G.B.2    Horner, J.W.3
  • 7
    • 0034892945 scopus 로고    scopus 로고
    • HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation
    • Antonchuk J, Sauvageau G, Humphries RK. HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation. Exp Hematol. 2001;29:1125-1134.
    • (2001) Exp Hematol , vol.29 , pp. 1125-1134
    • Antonchuk, J.1    Sauvageau, G.2    Humphries, R.K.3
  • 8
    • 0037023528 scopus 로고    scopus 로고
    • HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
    • Antonchuk J, Sauvegeau G, Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 2002;109:39-45.
    • (2002) Cell , vol.109 , pp. 39-45
    • Antonchuk, J.1    Sauvegeau, G.2    Humphries, R.K.3
  • 9
    • 0032188998 scopus 로고    scopus 로고
    • Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice
    • Bunting KD, Galipeau J, Topham D, Benaim E, Sorrentino BP. Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice. Blood. 1998;92:2269-2279.
    • (1998) Blood , vol.92 , pp. 2269-2279
    • Bunting, K.D.1    Galipeau, J.2    Topham, D.3    Benaim, E.4    Sorrentino, B.P.5
  • 10
    • 0034254733 scopus 로고    scopus 로고
    • Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo
    • Bunting DK, Zhou S, Lu T, Sorrentino BP. Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo. Blood. 2000;96:902-909.
    • (2000) Blood , vol.96 , pp. 902-909
    • Bunting, D.K.1    Zhou, S.2    Lu, T.3    Sorrentino, B.P.4
  • 11
    • 0036317908 scopus 로고    scopus 로고
    • Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation
    • de Guzman CG, Warren AJ, Zhang A, et al. Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation. Mol Cell Biol. 2002;22:5506-5517.
    • (2002) Mol Cell Biol , vol.22 , pp. 5506-5517
    • De Guzman, C.G.1    Warren, A.J.2    Zhang, A.3
  • 12
    • 0345167904 scopus 로고    scopus 로고
    • + hematopoietic cells using a single genetic element
    • + hematopoietic cells using a single genetic element. Blood. 2003;102: 4369-4376.
    • (2003) Blood , vol.102 , pp. 4369-4376
    • Mulloy, J.C.1    Cammenga, J.2    Berguido, F.J.3
  • 13
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferate capacity of normal and leukemic stem cells
    • Lessard J, Sauvageau G. Bmi-1 determines the proliferate capacity of normal and leukemic stem cells. Nature. 2003;423:255-260.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 14
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required tor maintenance of adult self-renewing hematopoietic stem cells
    • Park IK, Qian D, Kiel M, et al. Bmi-1 is required tor maintenance of adult self-renewing hematopoietic stem cells. Nature. 2003;423:302-305.
    • (2003) Nature , vol.423 , pp. 302-305
    • Park, I.K.1    Qian, D.2    Kiel, M.3
  • 15
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky AV, Pardal R, Iwashita T, et al. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature. 2003;425:962-967.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3
  • 16
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and polycomb-group gene bmi-1 regulates cell proliferation and senescence through an Ink4a locus
    • Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. The oncogene and polycomb-group gene bmi-1 regulates cell proliferation and senescence through an Ink4a locus. Nature. 1999;397:164-168.
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    Van Lohuizen, M.5
  • 17
    • 0029993450 scopus 로고    scopus 로고
    • Role of the Ink4a locus in tumor suppression and cell mortality
    • Serrano M, Lee H, Chin L, et al. Role of the Ink4a locus in tumor suppression and cell mortality. Cell. 1996;85:27-37.
    • (1996) Cell , vol.85 , pp. 27-37
    • Serrano, M.1    Lee, H.2    Chin, L.3
  • 18
    • 0030728468 scopus 로고    scopus 로고
    • Tumor suppression at the mouse Ink4a locus mediated by the alternative reading frame product p19Arf
    • Kamijo T, Zindy F, Roussel MF, et al. Tumor suppression at the mouse Ink4a locus mediated by the alternative reading frame product p19Arf. Cell. 1997;91:649-659.
    • (1997) Cell , vol.91 , pp. 649-659
    • Kamijo, T.1    Zindy, F.2    Roussel, M.F.3
  • 19
    • 0035817688 scopus 로고    scopus 로고
    • Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
    • Sharpless NE, Bardeesy N, Lee KH, et al. Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis. Nature. 2001;413:86-91.
    • (2001) Nature , vol.413 , pp. 86-91
    • Sharpless, N.E.1    Bardeesy, N.2    Lee, K.H.3
  • 20
    • 0035817687 scopus 로고    scopus 로고
    • Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice
    • Krimpenfort P, Quon KC, Mooi WS, Loonstra A, Berns A. Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice. Nature. 2001; 413:83-86.
    • (2001) Nature , vol.413 , pp. 83-86
    • Krimpenfort, P.1    Quon, K.C.2    Mooi, W.S.3    Loonstra, A.4    Berns, A.5
  • 21
    • 0347994891 scopus 로고    scopus 로고
    • Art tumor suppressor promoter monitors latent oncogenic signals in vivo
    • Zindy F, Williams RT, Baudino T, et al. Art tumor suppressor promoter monitors latent oncogenic signals in vivo. Proc Natl Acad Sci U S A. 2003; 100:15930-15935.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15930-15935
    • Zindy, F.1    Williams, R.T.2    Baudino, T.3
  • 22
    • 0032145569 scopus 로고    scopus 로고
    • Myc signaling via the Art tumor suppressor regulates p53-dependent apoptosis and immortalization
    • Zindy F, Eischen CM, Randle DH, et al. Myc signaling via the Art tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev. 1998;12:2424-2433.
    • (1998) Genes Dev , vol.12 , pp. 2424-2433
    • Zindy, F.1    Eischen, C.M.2    Randle, D.H.3
  • 23
    • 0034682721 scopus 로고    scopus 로고
    • Cellular senescence: Mitotic clock or culture shock?
    • Sherr CJ, DePinho RA. Cellular senescence: mitotic clock or culture shock? Cell. 2000;102:407-410.
    • (2000) Cell , vol.102 , pp. 407-410
    • Sherr, C.J.1    DePinho, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.