-
1
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
-
de Sauvage, F.J. et al. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature 369, 533-538 (1994).
-
(1994)
Nature
, vol.369
, pp. 533-538
-
-
De Sauvage, F.J.1
-
2
-
-
0028199208
-
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
-
Lok, S. et al. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 369, 565-568 (1994).
-
(1994)
Nature
, vol.369
, pp. 565-568
-
-
Lok, S.1
-
3
-
-
0028332474
-
Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin
-
Kaushansky, K. et al. Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature 369, 568-571 (1994).
-
(1994)
Nature
, vol.369
, pp. 568-571
-
-
Kaushansky, K.1
-
4
-
-
0028117771
-
The purification of megapoietin: A physiological regulator of megakaryocyte growth and platelet production
-
Kuter, D.J., Beeler, D.L. & Rosenberg, R.D. The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production. Proc. Natl. Acad. Sci. USA 91, 11104-11108 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11104-11108
-
-
Kuter, D.J.1
Beeler, D.L.2
Rosenberg, R.D.3
-
5
-
-
0028343099
-
Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl
-
Bartley, T.D. et al. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell 77, 1117-1124 (1994).
-
(1994)
Cell
, vol.77
, pp. 1117-1124
-
-
Bartley, T.D.1
-
6
-
-
0028086542
-
Thrombocytopenia in c-mpl-deficient mice
-
Gurney, A.L., Carver-Moore, K., de Sauvage, F.J. & Moore, M.W. Thrombocytopenia in c-mpl-deficient mice. Science 265, 1445-1447 (1994).
-
(1994)
Science
, vol.265
, pp. 1445-1447
-
-
Gurney, A.L.1
Carver-Moore, K.2
De Sauvage, F.J.3
Moore, M.W.4
-
7
-
-
0030307599
-
Dissection of c-Mpl and thrombopoietin function: Studies of knockout mice and receptor signal transduction
-
Gurney, A.L. & de Sauvage, F.J. Dissection of c-Mpl and thrombopoietin function: studies of knockout mice and receptor signal transduction. Stem Cells 14 (suppl. 1), 116-123 (1996).
-
(1996)
Stem Cells
, vol.14
, Issue.SUPPL. 1
, pp. 116-123
-
-
Gurney, A.L.1
De Sauvage, F.J.2
-
8
-
-
0030788804
-
Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin
-
Bunting, S. et al. Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin. Blood 90, 3423-3429 (1997).
-
(1997)
Blood
, vol.90
, pp. 3423-3429
-
-
Bunting, S.1
-
9
-
-
0030024685
-
Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin
-
de Sauvage, F.J. et al. Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin. J. Exp. Med. 183, 651-656 (1996).
-
(1996)
J. Exp. Med.
, vol.183
, pp. 651-656
-
-
De Sauvage, F.J.1
-
10
-
-
0033869985
-
Platelet production in the pulmonary capillary bed: New ultrastructural evidence for an old concept
-
Zucker-Franklin, D. & Philipp, C.S. Platelet production in the pulmonary capillary bed: new ultrastructural evidence for an old concept. Am. J. Pathol. 157, 69-74 (2000).
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 69-74
-
-
Zucker-Franklin, D.1
Philipp, C.S.2
-
11
-
-
0024574755
-
Localization of megakaryocytes in the bone marrow
-
Tavassoli, M. & Aoki, M. Localization of megakaryocytes in the bone marrow. Blood Cells 15, 3-14 (1989).
-
(1989)
Blood Cells
, vol.15
, pp. 3-14
-
-
Tavassoli, M.1
Aoki, M.2
-
12
-
-
0032227239
-
IL-3 does not contribute to platelet production in c-Mpl-deficient mice
-
Chen, Q., Solar, G., Eaton, D.L. & de Sauvage, F.J. IL-3 does not contribute to platelet production in c-Mpl-deficient mice. Stem Cells 16 (suppl. 2), 31-36 (1998).
-
(1998)
Stem Cells
, vol.16
, Issue.SUPPL. 2
, pp. 31-36
-
-
Chen, Q.1
Solar, G.2
Eaton, D.L.3
De Sauvage, F.J.4
-
13
-
-
0032522963
-
Cytokine production and function in c-mpl-deficient mice: No physiologic role for interleukin- 3 in residual megakaryocyte and platelet production
-
Gainsford, T. et al. Cytokine production and function in c-mpl-deficient mice: no physiologic role for interleukin-3 in residual megakaryocyte and platelet production. Blood 91, 2745-2752 (1998).
-
(1998)
Blood
, vol.91
, pp. 2745-2752
-
-
Gainsford, T.1
-
14
-
-
0034650935
-
The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin- 11, or leukemia inhibitory factor
-
Gainsford, T. et al. The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor. Blood 95, 528-534 (2000).
-
(2000)
Blood
, vol.95
, pp. 528-534
-
-
Gainsford, T.1
-
15
-
-
0032479867
-
Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation
-
Hamada, T. et al. Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation. J. Exp. Med. 188, 539-548 (1998).
-
(1998)
J. Exp. Med.
, vol.188
, pp. 539-548
-
-
Hamada, T.1
-
16
-
-
0032147012
-
The α-chemokine receptor CXCR 4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion
-
Wang, J.F., Liu, Z.Y. & Groopman, J.E. The α-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood 92, 756-764 (1998).
-
(1998)
Blood
, vol.92
, pp. 756-764
-
-
Wang, J.F.1
Liu, Z.Y.2
Groopman, J.E.3
-
17
-
-
0345040163
-
Phenotypic and functional evidence for the expression of CXCR 4 receptor during megakaryocytopoiesis
-
Riviere, C. et al. Phenotypic and functional evidence for the expression of CXCR4 receptor during megakaryocytopoiesis. Blood 93, 1511-1523 (1999).
-
(1999)
Blood
, vol.93
, pp. 1511-1523
-
-
Riviere, C.1
-
18
-
-
0034672426
-
Stromal-derived factor 1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases
-
Lane, W.J. et al. Stromal-derived factor 1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. Blood 96, 4152-4159 (2000).
-
(2000)
Blood
, vol.96
, pp. 4152-4159
-
-
Lane, W.J.1
-
19
-
-
0034672371
-
Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis
-
Majka, M. et al. Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis. Blood 96, 4142-4151 (2000).
-
(2000)
Blood
, vol.96
, pp. 4142-4151
-
-
Majka, M.1
-
20
-
-
0029119091
-
Effective prevention of thrombocytopenia in mice using adenovirus-mediated transfer of HST-1 (FGF-4) gene
-
Konishi, H. et al. Effective prevention of thrombocytopenia in mice using adenovirus-mediated transfer of HST-1 (FGF-4) gene. J. Clin. Invest. 96, 1125-1130 (1995).
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1125-1130
-
-
Konishi, H.1
-
21
-
-
0028589321
-
Adenovirus-mediated transfer of the HST-1 (FGF4) gene induces increased levels of platelet count in vivo
-
Sakamoto, H. et al. Adenovirus-mediated transfer of the HST-1 (FGF4) gene induces increased levels of platelet count in vivo. Proc. Natl. Acad. Sci. USA 91, 12368-12372 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12368-12372
-
-
Sakamoto, H.1
-
22
-
-
0037441869
-
Autocrine-paracrine VEGF loops potentiate the maturation of megakaryocytic precursors through Flt 1 receptor
-
Casella, I. et al. Autocrine-paracrine VEGF loops potentiate the maturation of megakaryocytic precursors through Flt1 receptor. Blood 101, 1316-1323 (2003).
-
(2003)
Blood
, vol.101
, pp. 1316-1323
-
-
Casella, I.1
-
23
-
-
0028232741
-
Isolation and characterization of human bone marrow microvascular endothelial cells: Hematopoietic progenitor cell adhesion
-
Rafii, S. et al. Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion. Blood 84, 10-19 (1994).
-
(1994)
Blood
, vol.84
, pp. 10-19
-
-
Rafii, S.1
-
24
-
-
0028864381
-
Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors
-
Rafii, S. et al. Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors. Blood 86, 3353-3363 (1995).
-
(1995)
Blood
, vol.86
, pp. 3353-3363
-
-
Rafii, S.1
-
25
-
-
0035869433
-
Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability
-
Corada, M. et al. Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability. Blood 97, 1679-1684 (2001).
-
(2001)
Blood
, vol.97
, pp. 1679-1684
-
-
Corada, M.1
-
26
-
-
0037111775
-
Differential movements of VE-cadherin and PECAM- 1 during transmigration of polymorphonuclear leukocytes through human umbilical vein endothelium
-
Su, W.H., Chen, H.I. & Jen, C.J. Differential movements of VE-cadherin and PECAM-1 during transmigration of polymorphonuclear leukocytes through human umbilical vein endothelium. Blood 100, 3597-3603 (2002).
-
(2002)
Blood
, vol.100
, pp. 3597-3603
-
-
Su, W.H.1
Chen, H.I.2
Jen, C.J.3
-
27
-
-
18444389451
-
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
-
Heissig, B. et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 109, 625-637 (2002).
-
(2002)
Cell
, vol.109
, pp. 625-637
-
-
Heissig, B.1
-
28
-
-
0036344496
-
+ stem cells from bone-marrow microenvironment
-
+ stem cells from bone-marrow microenvironment. Nat. Med. 8, 841-849 (2002).
-
(2002)
Nat. Med.
, vol.8
, pp. 841-849
-
-
Hattori, K.1
-
29
-
-
0036570220
-
Selective targeting of angiogenic tumor vasculature by vascular endothelial-cadherin antibody inhibits tumor growth without affecting vascular permeability
-
Liao, F. et al. Selective targeting of angiogenic tumor vasculature by vascular endothelial-cadherin antibody inhibits tumor growth without affecting vascular permeability. Cancer Res. 62, 2567-2575 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 2567-2575
-
-
Liao, F.1
-
30
-
-
0028323447
-
Modulation of megakaryocytopoiesis by human basic fibroblast growth factor
-
Avraham, H., Banu, N., Scadden, D.T., Abraham, J. & Groopman, J.E. Modulation of megakaryocytopoiesis by human basic fibroblast growth factor. Blood 83, 2126-2132 (1994).
-
(1994)
Blood
, vol.83
, pp. 2126-2132
-
-
Avraham, H.1
Banu, N.2
Scadden, D.T.3
Abraham, J.4
Groopman, J.E.5
-
31
-
-
0027242027
-
Characterization of adhesive interactions between human endothelial cells and megakaryocytes
-
Avraham, H., Cowley, S., Chi, S.Y., Jiang, S. & Groopman, J.E. Characterization of adhesive interactions between human endothelial cells and megakaryocytes. J. Clin. Invest. 91, 2378-2384 (1993).
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 2378-2384
-
-
Avraham, H.1
Cowley, S.2
Chi, S.Y.3
Jiang, S.4
Groopman, J.E.5
-
32
-
-
0026730776
-
Interaction of human bone marrow fibroblasts with megakaryocytes: Role of the c-kit ligand
-
Avraham, H. et al. Interaction of human bone marrow fibroblasts with megakaryocytes: role of the c-kit ligand. Blood 80, 1679-1684 (1992).
-
(1992)
Blood
, vol.80
, pp. 1679-1684
-
-
Avraham, H.1
-
33
-
-
0035883096
-
-/- mice can produce a normal level of platelets after administration of 5-fluorouracil: The effect of age on the response
-
-/- mice can produce a normal level of platelets after administration of 5-fluorouracil: the effect of age on the response. Blood 98, 1019-1027 (2001).
-
(2001)
Blood
, vol.98
, pp. 1019-1027
-
-
Levin, J.1
-
34
-
-
0036302147
-
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR 4
-
Petit, I. et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat. Immunol. 3, 687-694 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 687-694
-
-
Petit, I.1
-
35
-
-
0033524834
-
Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR 4
-
Peled, A. et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 283, 845-851 (1999).
-
(1999)
Science
, vol.283
, pp. 845-851
-
-
Peled, A.1
-
36
-
-
0037111558
-
Recombinant human thrombopoietin: Basic biology and evaluation of clinical studies
-
Kuter, D.J. & Begley, C.G. Recombinant human thrombopoietin: basic biology and evaluation of clinical studies. Blood 100, 3457-3469 (2002).
-
(2002)
Blood
, vol.100
, pp. 3457-3469
-
-
Kuter, D.J.1
Begley, C.G.2
-
37
-
-
0036517818
-
Whatever happened to thrombopoietin?
-
Kuter, D.J. Whatever happened to thrombopoietin? Transfusion 42, 279-283 (2002).
-
(2002)
Transfusion
, vol.42
, pp. 279-283
-
-
Kuter, D.J.1
-
38
-
-
0034050651
-
Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer
-
Vadhan-Raj, S. et al. Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer. Ann. Intern. Med. 132, 364-368 (2000).
-
(2000)
Ann. Intern. Med.
, vol.132
, pp. 364-368
-
-
Vadhan-Raj, S.1
-
39
-
-
0030798633
-
Expression and function of receptors for extracellular matrix molecules in the differentiation of human megakaryocytes in vitro
-
Mossuz, P., Schweitzer, A., Molla, A. & Berthier, R. Expression and function of receptors for extracellular matrix molecules in the differentiation of human megakaryocytes in vitro. Br. J. Haematol. 98, 819-827 (1997).
-
(1997)
Br. J. Haematol.
, vol.98
, pp. 819-827
-
-
Mossuz, P.1
Schweitzer, A.2
Molla, A.3
Berthier, R.4
-
40
-
-
0034142019
-
Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK)
-
Hodohara, K., Fujii, N., Yamamoto, N. & Kaushansky, K. Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK). Blood 95, 769-775 (2000).
-
(2000)
Blood
, vol.95
, pp. 769-775
-
-
Hodohara, K.1
Fujii, N.2
Yamamoto, N.3
Kaushansky, K.4
-
41
-
-
0037369260
-
Stromal inhibition of megakaryocytic differentiation is associated with blockade of sustained Rap 1 activation
-
Delehanty, L.L. et al. Stromal inhibition of megakaryocytic differentiation is associated with blockade of sustained Rap1 activation. Blood 101, 1744-1751 (2003).
-
(2003)
Blood
, vol.101
, pp. 1744-1751
-
-
Delehanty, L.L.1
-
42
-
-
0034055007
-
Regulation of megakaryocytopoiesis in an in vitro stroma model: Preferential adhesion of megakaryocytic progenitors and subsequent inhibition of maturation
-
Zweegman, S., Veenhof, M.A., Huijgens, P.C., Schuurhuis, G.J. & Drager, A.M. Regulation of megakaryocytopoiesis in an in vitro stroma model: preferential adhesion of megakaryocytic progenitors and subsequent inhibition of maturation. Exp. Hematol. 28, 401-410 (2000).
-
(2000)
Exp. Hematol.
, vol.28
, pp. 401-410
-
-
Zweegman, S.1
Veenhof, M.A.2
Huijgens, P.C.3
Schuurhuis, G.J.4
Drager, A.M.5
-
43
-
-
0031445929
-
Regulation of hematopoiesis by microvascular endothelium
-
Rafii, S., Mohle, R., Shapiro, F., Frey, B.M. & Moore, M.A. Regulation of hematopoiesis by microvascular endothelium. Leuk. Lymphoma 27, 375-386 (1997).
-
(1997)
Leuk Lymphoma
, vol.27
, pp. 375-386
-
-
Rafii, S.1
Mohle, R.2
Shapiro, F.3
Frey, B.M.4
Moore, M.A.5
-
44
-
-
0030258014
-
Isolation, characterization, and biologic features of bone marrow endothelial cells
-
Almeida-Porada, G. & Ascensao, J.L. Isolation, characterization, and biologic features of bone marrow endothelial cells. J. Lab. Clin. Med. 128, 399-407 (1996).
-
(1996)
J. Lab. Clin. Med.
, vol.128
, pp. 399-407
-
-
Almeida-Porada, G.1
Ascensao, J.L.2
-
45
-
-
0030030009
-
Constitutive expression of E-selectin and vascular cell adhesion molecule- 1 on endothelial cells of hematopoietic tissues
-
Schweitzer, K.M. et al. Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues. Am. J. Pathol. 148, 165-175 (1996).
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 165-175
-
-
Schweitzer, K.M.1
-
46
-
-
0028171294
-
Immuno-, lectin-, and enzyme-histochemical characterization of human bone marrow endothelium
-
Masek, L.C., Sweetenham, J.W., Whitehouse, J.M. & Schumacher, U. Immuno-, lectin-, and enzyme-histochemical characterization of human bone marrow endothelium. Exp. Hematol. 22, 1203-1239 (1994).
-
(1994)
Exp. Hematol.
, vol.22
, pp. 1203-1239
-
-
Masek, L.C.1
Sweetenham, J.W.2
Whitehouse, J.M.3
Schumacher, U.4
-
47
-
-
0031029290
-
Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets
-
Mohle, R., Green, D., Moore, M.A., Nachman, R.L. & Rafii, S. Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proc. Natl. Acad. Sci. USA 94, 663-668 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 663-668
-
-
Mohle, R.1
Green, D.2
Moore, M.A.3
Nachman, R.L.4
Rafii, S.5
-
48
-
-
0041411416
-
Importance of predosing of recombinant human thrombopoietin to reduce chemotherapy-induced early thrombocytopenia
-
Vadhan-Raj, S. et al. Importance of predosing of recombinant human thrombopoietin to reduce chemotherapy-induced early thrombocytopenia. J. Clin. Oncol. 21, 3158-3167 (2003).
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 3158-3167
-
-
Vadhan-Raj, S.1
-
49
-
-
0342980388
-
The murine chemokine receptor CXCR 4 is tightly regulated during T cell development and activation
-
Schabath, R. et al. The murine chemokine receptor CXCR4 is tightly regulated during T cell development and activation. J. Leukoc. Biol. 66, 996-1004 (1999).
-
(1999)
J. Leukoc. Biol.
, vol.66
, pp. 996-1004
-
-
Schabath, R.1
-
50
-
-
0038117657
-
Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: Rapid internalization and recycling upon activation
-
Forster, R. et al. Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation. J. Immunol. 160, 1522-1531 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 1522-1531
-
-
Forster, R.1
|