Role of the polycomb group gene BMI1 in normal and leukemic hematopoietic stem and progenitor cells

Current Opinion in Hematology

Volumn 17, Issue 4, 2010, Pages 294-299

  Schuringa, Jan J ^a   Vellenga, Edo ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

B cell specific MLV integration site 1; hematopoietic stem cell self renewal; leukemic transformation; oxidative stress; reactive oxygen species

Indexed keywords

ARF PROTEIN; BMI1 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; POLYCOMB GROUP PROTEIN; REACTIVE OXYGEN METABOLITE; BMI1 PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; REPRESSOR PROTEIN;

APOPTOSIS; CELL DIVISION; CELL EXPANSION; CELL RENEWAL; DNA DAMAGE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; LEUKEMIA; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVIEW; SENESCENCE; STEM CELL; BIOLOGICAL MODEL; CYTOLOGY; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

APOPTOSIS; DNA DAMAGE; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA; MODELS, BIOLOGICAL; MUTATION; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; REPRESSOR PROTEINS; STEM CELLS; POLYCOMB REPRESSIVE COMPLEX 1;

EID: 77954087743     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0b013e328338c439     Document Type: Review

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