Differential, dominant activation and inhibition of notch signalling and APP cleavage by truncations of PSEN1 in human disease deficits

Human Molecular Genetics

Volumn 23, Issue 3, 2014, Pages 602-617

  Newman, Morgan ^a   Wilson, Lachlan ^a   Verdile, Giuseppe ^b,c,d   Lim, Anne ^a   Khan, Imran ^b,c   Moussavi Nik, Seyyed Hani ^a   Pursglove, Sharon ^e   Chapman, Gavin ^e   Martins, Ralph N ^b,c   Lardelli, Michael ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b EDITH COWAN UNIVERSITY   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d CURTIN UNIVERSITY   (Australia)

^e VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; NEUROGENIN 1; NOTCH RECEPTOR; PRESENILIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; EMBRYO; EXON; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC TRANSCRIPTION; NONHUMAN; OPEN READING FRAME; PICK PRESENILE DEMENTIA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ZEBRA FISH;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOIDOGENIC PROTEINS; ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; EMBRYO, NONMAMMALIAN; EXONS; HEK293 CELLS; HIDRADENITIS SUPPURATIVA; HUMANS; INTRACELLULAR MEMBRANES; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUTATION; NERVE TISSUE PROTEINS; PICK DISEASE OF THE BRAIN; PRESENILIN-1; PRESENILIN-2; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84892449716     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt448     Document Type: Article

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