A role for presenilins in autophagy revisited: Normal acidification of lysosomes in cells lacking PSEN1 and PSEN2

Journal of Neuroscience

Volumn 32, Issue 25, 2012, Pages 8633-8648

  Zhang, Xulun ^a   Garbett, Krassimira ^b   Veeraraghavalu, Karthikeyan ^a   Wilburn, Brian ^a   Gilmore, Reid ^c   Mirnics, Karoly ^b   Sisodia, Sangram S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN D; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 2; NEURON SPECIFIC NUCLEAR PROTEIN; PRESENILIN; PRESENILIN 1; PRESENILIN 2; PROTEIN P62; SMALL INTERFERING RNA;

ACIDIFICATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; EMBRYO; FLUORESCENCE MICROSCOPY; FRONTAL CORTEX; GENE EXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; LYSOSOME; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN MICROARRAY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BLASTOCYST; BLOTTING, WESTERN; CATHEPSIN D; CELL LINE, TUMOR; CELLS, CULTURED; DNA PRIMERS; GENE EXPRESSION; HUMANS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MICE; MICE, KNOCKOUT; NEURONS; POLYMERASE CHAIN REACTION; PRESENILIN-1; PRESENILIN-2; PRESENILINS; RNA; RNA, SMALL INTERFERING; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84862883617     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0556-12.2012     Document Type: Article

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