DAPT protects brain against cerebral ischemia by down-regulating the expression of Notch 1 and Nuclear factor kappa B in rats

Neurological Sciences

Volumn 33, Issue 6, 2012, Pages 1257-1264

  Li, Shuya ^a   Zhang, Xiangjian ^b   Wang, Yongjun ^a   Ji, Hui ^b   Du, Yuanyuan ^b   Liu, Haichao ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral ischemia; DAPT; Inflammation; Notch 1; Nuclear factor kappa B

Indexed keywords

GAMMA SECRETASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N [N (3,5 DIFLUOROPHENACETYL) 1 ALANYL]PHENYLGLYCINE TERT BUTYL ESTER; NEUROPROTECTIVE AGENT; NOTCH1 RECEPTOR; UNCLASSIFIED DRUG; DIPEPTIDE; N (N (3,5 DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT BUTYL ESTER; N-(N-(3,5-DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT-BUTYL ESTER; NOTCH1 PROTEIN, RAT; SECRETASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; BRAIN WATER; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; WATER CONTENT; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BRAIN; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; PHYSIOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BRAIN; BRAIN ISCHEMIA; DIPEPTIDES; DOWN-REGULATION; GENE EXPRESSION REGULATION; INJECTIONS, INTRAVENTRICULAR; MALE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, NOTCH1;

EID: 84883550398     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-012-0948-6     Document Type: Article

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