-
1
-
-
84878341989
-
Acute lymphoblastic leukaemia
-
Inaba H., Greaves M., Mullighan C.G. Acute lymphoblastic leukaemia. Lancet 2013, 381(9881):1943-1955.
-
(2013)
Lancet
, vol.381
, Issue.9881
, pp. 1943-1955
-
-
Inaba, H.1
Greaves, M.2
Mullighan, C.G.3
-
2
-
-
0036344108
-
Cytogenetics and molecular genetics of acute lymphoblastic leukemia
-
Harrison C.J., Foroni L. Cytogenetics and molecular genetics of acute lymphoblastic leukemia. Rev Clin Exp Hematol 2002, 6(2):91-113.
-
(2002)
Rev Clin Exp Hematol
, vol.6
, Issue.2
, pp. 91-113
-
-
Harrison, C.J.1
Foroni, L.2
-
4
-
-
0033619452
-
Prenatal origin of acute lymphoblastic leukaemia in children
-
Wiemels J.L., Cazzaniga G., Daniotti M., et al. Prenatal origin of acute lymphoblastic leukaemia in children. Lancet 1999, 354(9189):1499-1503.
-
(1999)
Lancet
, vol.354
, Issue.9189
, pp. 1499-1503
-
-
Wiemels, J.L.1
Cazzaniga, G.2
Daniotti, M.3
-
5
-
-
0027259413
-
Cytogenetically different leukemic clones at relapse of childhood acute lymphoblastic leukemia
-
Raimondi S.C., Pui C.H., Head D.R., Rivera G.K., Behm F.G. Cytogenetically different leukemic clones at relapse of childhood acute lymphoblastic leukemia. Blood 1993, 82(2):576-580.
-
(1993)
Blood
, vol.82
, Issue.2
, pp. 576-580
-
-
Raimondi, S.C.1
Pui, C.H.2
Head, D.R.3
Rivera, G.K.4
Behm, F.G.5
-
6
-
-
34147224008
-
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
-
Mullighan C.G., Goorha S., Radtke I., et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 2007, 446(7137):758-764.
-
(2007)
Nature
, vol.446
, Issue.7137
, pp. 758-764
-
-
Mullighan, C.G.1
Goorha, S.2
Radtke, I.3
-
7
-
-
43049139905
-
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
-
Mullighan C.G., Miller C.B., Radtke I., et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature 2008, 453(7191):110-114.
-
(2008)
Nature
, vol.453
, Issue.7191
, pp. 110-114
-
-
Mullighan, C.G.1
Miller, C.B.2
Radtke, I.3
-
8
-
-
58749109707
-
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
-
Mullighan C.G., Su X., Zhang J., et al. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med 2009, 360(5):470-480.
-
(2009)
N Engl J Med
, vol.360
, Issue.5
, pp. 470-480
-
-
Mullighan, C.G.1
Su, X.2
Zhang, J.3
-
9
-
-
84861633881
-
The pediatric cancer genome project
-
Downing J.R., Wilson R.K., Zhang J., et al. The pediatric cancer genome project. Nat Genet 2012, 44(6):619-622.
-
(2012)
Nat Genet
, vol.44
, Issue.6
, pp. 619-622
-
-
Downing, J.R.1
Wilson, R.K.2
Zhang, J.3
-
10
-
-
84862907593
-
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
-
Zhang J., Ding L., Holmfeldt L., et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 2012, 481(7380):157-163.
-
(2012)
Nature
, vol.481
, Issue.7380
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
-
11
-
-
84874647204
-
The genomic landscape of hypodiploid acute lymphoblastic leukemia
-
Holmfeldt L., Wei L., Diaz-Flores E., et al. The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet 2013, 45(3):242-252.
-
(2013)
Nat Genet
, vol.45
, Issue.3
, pp. 242-252
-
-
Holmfeldt, L.1
Wei, L.2
Diaz-Flores, E.3
-
12
-
-
84943642443
-
Whole genome sequence analysis of 22 MLL rearranged infant acute lymphoblastic leukemias reveals remarkably few somatic mutations: a report from the St Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project
-
Andersson A.K., Ma J., Wang J., et al. Whole genome sequence analysis of 22 MLL rearranged infant acute lymphoblastic leukemias reveals remarkably few somatic mutations: a report from the St Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project. ASH Annual Meeting Abstracts 2011, 118(21):69.
-
(2011)
ASH Annual Meeting Abstracts
, vol.118
, Issue.21
, pp. 69
-
-
Andersson, A.K.1
Ma, J.2
Wang, J.3
-
13
-
-
84865118132
-
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
-
Roberts K.G., Morin R.D., Zhang J., et al. Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell 2012, 22(2):153-166.
-
(2012)
Cancer Cell
, vol.22
, Issue.2
, pp. 153-166
-
-
Roberts, K.G.1
Morin, R.D.2
Zhang, J.3
-
14
-
-
84859209595
-
The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia
-
Moorman A.V. The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia. Blood Rev 2012, 26(3):123-135.
-
(2012)
Blood Rev
, vol.26
, Issue.3
, pp. 123-135
-
-
Moorman, A.V.1
-
15
-
-
70350497118
-
Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study
-
Balgobind B.V., Raimondi S.C., Harbott J., et al. Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study. Blood 2009, 114(12):2489-2496.
-
(2009)
Blood
, vol.114
, Issue.12
, pp. 2489-2496
-
-
Balgobind, B.V.1
Raimondi, S.C.2
Harbott, J.3
-
16
-
-
70350519430
-
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
-
Russell L.J., Capasso M., Vater I., et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood 2009, 114(13):2688-2698.
-
(2009)
Blood
, vol.114
, Issue.13
, pp. 2688-2698
-
-
Russell, L.J.1
Capasso, M.2
Vater, I.3
-
17
-
-
70350680415
-
Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia
-
Mullighan C.G., Collins-Underwood J.R., Phillips L.A., et al. Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet 2009, 41(11):1243-1246.
-
(2009)
Nat Genet
, vol.41
, Issue.11
, pp. 1243-1246
-
-
Mullighan, C.G.1
Collins-Underwood, J.R.2
Phillips, L.A.3
-
18
-
-
77949910163
-
Immunoglobulin heavy chain (IGH) locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL): rare clinical curios or potent genetic drivers?
-
Dyer M.J., Akasaka T., Capasso M., et al. Immunoglobulin heavy chain (IGH) locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL): rare clinical curios or potent genetic drivers?. Blood 2010, 115(8):1490-1499.
-
(2010)
Blood
, vol.115
, Issue.8
, pp. 1490-1499
-
-
Dyer, M.J.1
Akasaka, T.2
Capasso, M.3
-
19
-
-
84881258981
-
Chromosomal translocations involving the IGH@ locus in B-cell precursor acute lymphoblastic leukemia: 29 new cases and a review of the literature
-
Chapiro E., Radford-Weiss I., Cung H.A., et al. Chromosomal translocations involving the IGH@ locus in B-cell precursor acute lymphoblastic leukemia: 29 new cases and a review of the literature. Cancer Genet 2013, 206(5):162-173.
-
(2013)
Cancer Genet
, vol.206
, Issue.5
, pp. 162-173
-
-
Chapiro, E.1
Radford-Weiss, I.2
Cung, H.A.3
-
20
-
-
42649124306
-
Molecular pathogenesis of T-cell leukaemia and lymphoma
-
Aifantis I., Raetz E., Buonamici S. Molecular pathogenesis of T-cell leukaemia and lymphoma. Nat Rev Immunol 2008, 8(5):380-390.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.5
, pp. 380-390
-
-
Aifantis, I.1
Raetz, E.2
Buonamici, S.3
-
21
-
-
84856756817
-
ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy
-
Bhojwani D., Pei D., Sandlund J.T., et al. ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy. Leukemia 2012, 26(2):265-270.
-
(2012)
Leukemia
, vol.26
, Issue.2
, pp. 265-270
-
-
Bhojwani, D.1
Pei, D.2
Sandlund, J.T.3
-
22
-
-
33947375681
-
Age-related differences in leukemia biology and prognosis: the paradigm of MLL-AF4-positive acute lymphoblastic leukemia
-
Pui C.H., Campana D. Age-related differences in leukemia biology and prognosis: the paradigm of MLL-AF4-positive acute lymphoblastic leukemia. Leukemia 2007, 21(4):593-594.
-
(2007)
Leukemia
, vol.21
, Issue.4
, pp. 593-594
-
-
Pui, C.H.1
Campana, D.2
-
23
-
-
78149276142
-
Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005
-
Arico M., Schrappe M., Hunger S.P., et al. Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005. J Clin Oncol 2010, 28(31):4755-4761.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4755-4761
-
-
Arico, M.1
Schrappe, M.2
Hunger, S.P.3
-
24
-
-
2942563738
-
Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia
-
Harrison C.J., Moorman A.V., Broadfield Z.J., et al. Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia. Br J Haematol 2004, 125(5):552-559.
-
(2004)
Br J Haematol
, vol.125
, Issue.5
, pp. 552-559
-
-
Harrison, C.J.1
Moorman, A.V.2
Broadfield, Z.J.3
-
25
-
-
0345529967
-
Reassessment of the prognostic significance of hypodiploidy in pediatric patients with acute lymphoblastic leukemia
-
Raimondi S.C., Zhou Y., Mathew S., et al. Reassessment of the prognostic significance of hypodiploidy in pediatric patients with acute lymphoblastic leukemia. Cancer 2003, 98(12):2715-2722.
-
(2003)
Cancer
, vol.98
, Issue.12
, pp. 2715-2722
-
-
Raimondi, S.C.1
Zhou, Y.2
Mathew, S.3
-
26
-
-
34249733805
-
High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression
-
Kuiper R.P., Schoenmakers E.F., van Reijmersdal S.V., et al. High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression. Leukemia 2007, 21(6):1258-1266.
-
(2007)
Leukemia
, vol.21
, Issue.6
, pp. 1258-1266
-
-
Kuiper, R.P.1
Schoenmakers, E.F.2
van Reijmersdal, S.V.3
-
27
-
-
79960061227
-
Single nucleotide polymorphism microarray analysis of genetic alterations in cancer
-
Mullighan C.G. Single nucleotide polymorphism microarray analysis of genetic alterations in cancer. Methods Mol Biol 2011, 730:235-258.
-
(2011)
Methods Mol Biol
, vol.730
, pp. 235-258
-
-
Mullighan, C.G.1
-
28
-
-
57549097632
-
Global genomic characterization of acute lymphoblastic leukemia
-
Mullighan C.G., Downing J.R. Global genomic characterization of acute lymphoblastic leukemia. Semin Hematol 2009, 46(1):3-15.
-
(2009)
Semin Hematol
, vol.46
, Issue.1
, pp. 3-15
-
-
Mullighan, C.G.1
Downing, J.R.2
-
29
-
-
38349177862
-
Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray
-
Kawamata N., Ogawa S., Zimmermann M., et al. Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray. Blood 2008, 111(2):776-784.
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 776-784
-
-
Kawamata, N.1
Ogawa, S.2
Zimmermann, M.3
-
30
-
-
80052922387
-
Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group
-
Zhang J., Mullighan C.G., Harvey R.C., et al. Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood 2011, 118(11):3080-3087.
-
(2011)
Blood
, vol.118
, Issue.11
, pp. 3080-3087
-
-
Zhang, J.1
Mullighan, C.G.2
Harvey, R.C.3
-
31
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng A.P., Ferrando A.A., Lee W., et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004, 306(5694):269-271.
-
(2004)
Science
, vol.306
, Issue.5694
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
-
32
-
-
70149087158
-
High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia
-
Gutierrez A., Sanda T., Grebliunaite R., et al. High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia. Blood 2009, 114(3):647-650.
-
(2009)
Blood
, vol.114
, Issue.3
, pp. 647-650
-
-
Gutierrez, A.1
Sanda, T.2
Grebliunaite, R.3
-
33
-
-
70349232830
-
WT1 mutations in T-ALL
-
Tosello V., Mansour M.R., Barnes K., et al. WT1 mutations in T-ALL. Blood 2009, 114(5):1038-1045.
-
(2009)
Blood
, vol.114
, Issue.5
, pp. 1038-1045
-
-
Tosello, V.1
Mansour, M.R.2
Barnes, K.3
-
34
-
-
34547780475
-
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors
-
O'Neil J., Grim J., Strack P., et al. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors. J Exp Med 2007, 204(8):1813-1824.
-
(2007)
J Exp Med
, vol.204
, Issue.8
, pp. 1813-1824
-
-
O'Neil, J.1
Grim, J.2
Strack, P.3
-
35
-
-
84883050573
-
The silent mutational landscape of infant MLL-AF4 pro-B acute lymphoblastic leukemia
-
Dobbins S.E., Sherborne A.L., Ma Y.P., et al. The silent mutational landscape of infant MLL-AF4 pro-B acute lymphoblastic leukemia. Genes Chromosomes Cancer 2013, 52(10):954-960.
-
(2013)
Genes Chromosomes Cancer
, vol.52
, Issue.10
, pp. 954-960
-
-
Dobbins, S.E.1
Sherborne, A.L.2
Ma, Y.P.3
-
36
-
-
57149113918
-
The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1
-
Parker H., An Q., Barber K., et al. The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1. Genes Chromosomes Cancer 2008, 47(12):1118-1125.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, Issue.12
, pp. 1118-1125
-
-
Parker, H.1
An, Q.2
Barber, K.3
-
37
-
-
77954609243
-
Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia
-
Virely C., Moulin S., Cobaleda C., et al. Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia. Leukemia 2010, 24(6):1200-1204.
-
(2010)
Leukemia
, vol.24
, Issue.6
, pp. 1200-1204
-
-
Virely, C.1
Moulin, S.2
Cobaleda, C.3
-
38
-
-
79958288742
-
Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia
-
Heltemes-Harris L.M., Willette M.J., Ramsey L.B., et al. Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia. J Exp Med 2011, 208(6):1135-1149.
-
(2011)
J Exp Med
, vol.208
, Issue.6
, pp. 1135-1149
-
-
Heltemes-Harris, L.M.1
Willette, M.J.2
Ramsey, L.B.3
-
39
-
-
77957796750
-
The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party
-
Iacobucci I., Lonetti A., Paoloni F., et al. The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party. Haematologica 2010, 95(10):1683-1690.
-
(2010)
Haematologica
, vol.95
, Issue.10
, pp. 1683-1690
-
-
Iacobucci, I.1
Lonetti, A.2
Paoloni, F.3
-
40
-
-
70349242044
-
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell' Adulto Acute Leukemia Working Party (GIMEMA AL WP)
-
Iacobucci I., Storlazzi C.T., Cilloni D., et al. Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell' Adulto Acute Leukemia Working Party (GIMEMA AL WP). Blood 2009, 114(10):2159-2167.
-
(2009)
Blood
, vol.114
, Issue.10
, pp. 2159-2167
-
-
Iacobucci, I.1
Storlazzi, C.T.2
Cilloni, D.3
-
41
-
-
70449719091
-
IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report
-
Martinelli G., Iacobucci I., Storlazzi C.T., et al. IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report. J Clin Oncol 2009, 27(31):5202-5207.
-
(2009)
J Clin Oncol
, vol.27
, Issue.31
, pp. 5202-5207
-
-
Martinelli, G.1
Iacobucci, I.2
Storlazzi, C.T.3
-
42
-
-
58749097408
-
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study
-
Den Boer M.L., van Slegtenhorst M., De Menezes R.X., et al. A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. Lancet Oncol 2009, 10(2):125-134.
-
(2009)
Lancet Oncol
, vol.10
, Issue.2
, pp. 125-134
-
-
Den Boer, M.L.1
van Slegtenhorst, M.2
De Menezes, R.X.3
-
43
-
-
0028001362
-
The Ikaros gene is required for the development of all lymphoid lineages
-
Georgopoulos K., Bigby M., Wang J.H., et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994, 79(1):143-156.
-
(1994)
Cell
, vol.79
, Issue.1
, pp. 143-156
-
-
Georgopoulos, K.1
Bigby, M.2
Wang, J.H.3
-
44
-
-
77949425065
-
Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia
-
Chapiro E., Russell L., Lainey E., et al. Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia. Leukemia 2010, 24(3):642-645.
-
(2010)
Leukemia
, vol.24
, Issue.3
, pp. 642-645
-
-
Chapiro, E.1
Russell, L.2
Lainey, E.3
-
45
-
-
77649214639
-
Down syndrome acute lymphoblastic leukemia: a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the iBFM Study Group
-
Hertzberg L., Vendramini E., Ganmore I., et al. Down syndrome acute lymphoblastic leukemia: a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the iBFM Study Group. Blood 2010, 115(5):1006-1017.
-
(2010)
Blood
, vol.115
, Issue.5
, pp. 1006-1017
-
-
Hertzberg, L.1
Vendramini, E.2
Ganmore, I.3
-
46
-
-
42249091014
-
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia
-
Flex E., Petrangeli V., Stella L., et al. Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia. J Exp Med 2008, 205(4):751-758.
-
(2008)
J Exp Med
, vol.205
, Issue.4
, pp. 751-758
-
-
Flex, E.1
Petrangeli, V.2
Stella, L.3
-
47
-
-
54349086521
-
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome
-
Bercovich D., Ganmore I., Scott L.M., et al. Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome. Lancet 2008, 372(9648):1484-1492.
-
(2008)
Lancet
, vol.372
, Issue.9648
, pp. 1484-1492
-
-
Bercovich, D.1
Ganmore, I.2
Scott, L.M.3
-
48
-
-
67249146555
-
JAK mutations in high-risk childhood acute lymphoblastic leukemia
-
Mullighan C.G., Zhang J., Harvey R.C., et al. JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A 2009, 106:9414-9418.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9414-9418
-
-
Mullighan, C.G.1
Zhang, J.2
Harvey, R.C.3
-
49
-
-
60249086789
-
A specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukaemia
-
Kearney L., Gonzalez De Castro D., Yeung J., et al. A specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukaemia. Blood 2008, 113:646-648.
-
(2008)
Blood
, vol.113
, pp. 646-648
-
-
Kearney, L.1
Gonzalez De Castro, D.2
Yeung, J.3
-
50
-
-
84864440264
-
Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia
-
Tasian S.K., Doral M.Y., Borowitz M.J., et al. Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia. Blood 2012, 120(4):833-842.
-
(2012)
Blood
, vol.120
, Issue.4
, pp. 833-842
-
-
Tasian, S.K.1
Doral, M.Y.2
Borowitz, M.J.3
-
51
-
-
84868528389
-
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
-
Maude S.L., Tasian S.K., Vincent T., et al. Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia. Blood 2012, 120(17):3510-3518.
-
(2012)
Blood
, vol.120
, Issue.17
, pp. 3510-3518
-
-
Maude, S.L.1
Tasian, S.K.2
Vincent, T.3
-
52
-
-
77954516863
-
Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
-
Harvey R.C., Mullighan C.G., Chen I.M., et al. Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. Blood 2010, 115(26):5312-5321.
-
(2010)
Blood
, vol.115
, Issue.26
, pp. 5312-5321
-
-
Harvey, R.C.1
Mullighan, C.G.2
Chen, I.M.3
-
53
-
-
78649742010
-
Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome
-
Harvey R.C., Mullighan C.G., Wang X., et al. Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome. Blood 2010, 116(23):4874-4884.
-
(2010)
Blood
, vol.116
, Issue.23
, pp. 4874-4884
-
-
Harvey, R.C.1
Mullighan, C.G.2
Wang, X.3
-
54
-
-
77954500629
-
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol
-
Cario G., Zimmermann M., Romey R., et al. Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol. Blood 2010, 115(26):5393-5397.
-
(2010)
Blood
, vol.115
, Issue.26
, pp. 5393-5397
-
-
Cario, G.1
Zimmermann, M.2
Romey, R.3
-
55
-
-
79951845044
-
Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial
-
Ensor H.M., Schwab C., Russell L.J., et al. Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial. Blood 2011, 117(7):2129-2136.
-
(2011)
Blood
, vol.117
, Issue.7
, pp. 2129-2136
-
-
Ensor, H.M.1
Schwab, C.2
Russell, L.J.3
-
56
-
-
84859820034
-
Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study
-
Chen I.M., Harvey R.C., Mullighan C.G., et al. Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study. Blood 2012, 119(15):3512-3522.
-
(2012)
Blood
, vol.119
, Issue.15
, pp. 3512-3522
-
-
Chen, I.M.1
Harvey, R.C.2
Mullighan, C.G.3
-
57
-
-
84872457525
-
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project
-
Loh M.L., Zhang J., Harvey R.C., et al. Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project. Blood 2013, 121(3):485-488.
-
(2013)
Blood
, vol.121
, Issue.3
, pp. 485-488
-
-
Loh, M.L.1
Zhang, J.2
Harvey, R.C.3
-
58
-
-
77953193307
-
Lnk constrains myeloproliferative diseases in mice
-
Bersenev A., Wu C., Balcerek J., et al. Lnk constrains myeloproliferative diseases in mice. J Clin Invest 2010, 120(6):2058-2069.
-
(2010)
J Clin Invest
, vol.120
, Issue.6
, pp. 2058-2069
-
-
Bersenev, A.1
Wu, C.2
Balcerek, J.3
-
59
-
-
84886513092
-
Tyrosine kinase inhibitor therapy induces remission in a patient with refractory EBF1-PDGFRB-positive acute lymphoblastic leukemia
-
Weston B.W., Hayden M.A., Roberts K.G., et al. Tyrosine kinase inhibitor therapy induces remission in a patient with refractory EBF1-PDGFRB-positive acute lymphoblastic leukemia. J Clin Oncol 2013, 31(25):e413-e416.
-
(2013)
J Clin Oncol
, vol.31
, Issue.25
-
-
Weston, B.W.1
Hayden, M.A.2
Roberts, K.G.3
-
60
-
-
13044264463
-
Hypodiploidy with less than 45 chromosomes confers adverse risk in childhood acute lymphoblastic leukemia: a report from the children's cancer group
-
Heerema N.A., Nachman J.B., Sather H.N., et al. Hypodiploidy with less than 45 chromosomes confers adverse risk in childhood acute lymphoblastic leukemia: a report from the children's cancer group. Blood 1999, 94(12):4036-4045.
-
(1999)
Blood
, vol.94
, Issue.12
, pp. 4036-4045
-
-
Heerema, N.A.1
Nachman, J.B.2
Sather, H.N.3
-
61
-
-
0023260072
-
Hypodiploidy is associated with a poor prognosis in childhood acute lymphoblastic leukemia
-
Pui C.H., Williams D.L., Raimondi S.C., et al. Hypodiploidy is associated with a poor prognosis in childhood acute lymphoblastic leukemia. Blood 1987, 70(1):247-253.
-
(1987)
Blood
, vol.70
, Issue.1
, pp. 247-253
-
-
Pui, C.H.1
Williams, D.L.2
Raimondi, S.C.3
-
62
-
-
84876447944
-
Identification of TP53 as an acute lymphocytic leukemia susceptibility gene through exome sequencing
-
Powell B.C., Jiang L., Muzny D.M., et al. Identification of TP53 as an acute lymphocytic leukemia susceptibility gene through exome sequencing. Pediatr Blood Cancer 2013, 60(6):E1-E3.
-
(2013)
Pediatr Blood Cancer
, vol.60
, Issue.6
-
-
Powell, B.C.1
Jiang, L.2
Muzny, D.M.3
-
63
-
-
84884999671
-
-
A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia. Nat Genet. In press. doi:10.1038/ng.2754.
-
Shah S, Schrader KA, Waanders E, et al. A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia. Nat Genet. In press. doi:10.1038/ng.2754.
-
-
-
Shah, S.1
Schrader, K.A.2
Waanders, E.3
-
64
-
-
33947257508
-
Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21)
-
Moorman A.V., Richards S.M., Robinson H.M., et al. Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21). Blood 2007, 109(6):2327-2330.
-
(2007)
Blood
, vol.109
, Issue.6
, pp. 2327-2330
-
-
Moorman, A.V.1
Richards, S.M.2
Robinson, H.M.3
-
65
-
-
33947131584
-
Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle
-
Robinson H.M., Harrison C.J., Moorman A.V., Chudoba I., Strefford J.C. Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle. Genes Chromosomes Cancer 2007, 46(4):318-326.
-
(2007)
Genes Chromosomes Cancer
, vol.46
, Issue.4
, pp. 318-326
-
-
Robinson, H.M.1
Harrison, C.J.2
Moorman, A.V.3
Chudoba, I.4
Strefford, J.C.5
-
66
-
-
33744474290
-
Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21
-
Strefford J.C., van Delft F.W., Robinson H.M., et al. Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21. Proc Natl Acad Sci U S A 2006, 103(21):8167-8172.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.21
, pp. 8167-8172
-
-
Strefford, J.C.1
van Delft, F.W.2
Robinson, H.M.3
-
67
-
-
84887513571
-
Risk-directed treatment intensification significantly reduces the risk of relapse among children and adolescents with acute lymphoblastic leukemia and intrachromosomal amplification of chromosome 21: a comparison of the MRC ALL97/99 and UKALL2003 Trials
-
Moorman A.V., Robinson H., Schwab C., et al. Risk-directed treatment intensification significantly reduces the risk of relapse among children and adolescents with acute lymphoblastic leukemia and intrachromosomal amplification of chromosome 21: a comparison of the MRC ALL97/99 and UKALL2003 Trials. J Clin Oncol 2013, 31(27):3389-3396.
-
(2013)
J Clin Oncol
, vol.31
, Issue.27
, pp. 3389-3396
-
-
Moorman, A.V.1
Robinson, H.2
Schwab, C.3
-
68
-
-
57549119069
-
ERG deletions define a novel subtype of B-progenitor acute lymphoblastic leukemia
-
Mullighan C.G., Miller C.B., Su X., et al. ERG deletions define a novel subtype of B-progenitor acute lymphoblastic leukemia. Blood (ASH Annual Meeting Abstracts) 2007, 110(11):691.
-
(2007)
Blood (ASH Annual Meeting Abstracts)
, vol.110
, Issue.11
, pp. 691
-
-
Mullighan, C.G.1
Miller, C.B.2
Su, X.3
-
69
-
-
77950299929
-
PHF6 mutations in T-cell acute lymphoblastic leukemia
-
Van Vlierberghe P., Palomero T., Khiabanian H., et al. PHF6 mutations in T-cell acute lymphoblastic leukemia. Nat Genet 2010, 42(4):338-342.
-
(2010)
Nat Genet
, vol.42
, Issue.4
, pp. 338-342
-
-
Van Vlierberghe, P.1
Palomero, T.2
Khiabanian, H.3
-
70
-
-
78651299314
-
PHF6 mutations in adult acute myeloid leukemia
-
Van Vlierberghe P., Patel J., Abdel-Wahab O., et al. PHF6 mutations in adult acute myeloid leukemia. Leukemia 2011, 25(1):130-134.
-
(2011)
Leukemia
, vol.25
, Issue.1
, pp. 130-134
-
-
Van Vlierberghe, P.1
Patel, J.2
Abdel-Wahab, O.3
-
71
-
-
84864627629
-
PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex
-
Todd M.A., Picketts D.J. PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex. J Proteome Res 2012, 11(8):4326-4337.
-
(2012)
J Proteome Res
, vol.11
, Issue.8
, pp. 4326-4337
-
-
Todd, M.A.1
Picketts, D.J.2
-
72
-
-
84873303336
-
PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis
-
Wang J., Leung J.W., Gong Z., Feng L., Shi X., Chen J. PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis. J Biol Chem 2013, 288(5):3174-3183.
-
(2013)
J Biol Chem
, vol.288
, Issue.5
, pp. 3174-3183
-
-
Wang, J.1
Leung, J.W.2
Gong, Z.3
Feng, L.4
Shi, X.5
Chen, J.6
-
73
-
-
58749095816
-
Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia
-
Coustan-Smith E., Mullighan C.G., Onciu M., et al. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol 2009, 10(2):147-156.
-
(2009)
Lancet Oncol
, vol.10
, Issue.2
, pp. 147-156
-
-
Coustan-Smith, E.1
Mullighan, C.G.2
Onciu, M.3
-
74
-
-
84855793253
-
Clinical significance of early T-cell precursor acute lymphoblastic leukaemia: results of the Tokyo Children's Cancer Study Group Study L99-15
-
Inukai T., Kiyokawa N., Campana D., et al. Clinical significance of early T-cell precursor acute lymphoblastic leukaemia: results of the Tokyo Children's Cancer Study Group Study L99-15. Br J Haematol 2012, 156(3):358-365.
-
(2012)
Br J Haematol
, vol.156
, Issue.3
, pp. 358-365
-
-
Inukai, T.1
Kiyokawa, N.2
Campana, D.3
-
75
-
-
79551693621
-
Patients with early t-cell precursor (ETP) acute lymphoblastic leukemia (ALL) have high levels of minimal residual disease (MRD) at the end of induction-a Children's Oncology Group (COG) study
-
Wood B., Winter S., Dunsmore K., et al. Patients with early t-cell precursor (ETP) acute lymphoblastic leukemia (ALL) have high levels of minimal residual disease (MRD) at the end of induction-a Children's Oncology Group (COG) study. Blood (ASH Annual Meeting Abstracts) 2009, 114(22):9.
-
(2009)
Blood (ASH Annual Meeting Abstracts)
, vol.114
, Issue.22
, pp. 9
-
-
Wood, B.1
Winter, S.2
Dunsmore, K.3
-
76
-
-
37549010335
-
Launching the T-cell-lineage developmental programme
-
Rothenberg E.V., Moore J.E., Yui M.A. Launching the T-cell-lineage developmental programme. Nat Rev Immunol 2008, 8(1):9-21.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.1
, pp. 9-21
-
-
Rothenberg, E.V.1
Moore, J.E.2
Yui, M.A.3
-
77
-
-
84875135862
-
Criteria for inference of chromothripsis in cancer genomes
-
Korbel J.O., Campbell P.J. Criteria for inference of chromothripsis in cancer genomes. Cell 2013, 152(6):1226-1236.
-
(2013)
Cell
, vol.152
, Issue.6
, pp. 1226-1236
-
-
Korbel, J.O.1
Campbell, P.J.2
-
78
-
-
84862776920
-
Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL
-
Della Gatta G., Palomero T., Perez-Garcia A., et al. Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL. Nat Med 2012, 18(3):436-440.
-
(2012)
Nat Med
, vol.18
, Issue.3
, pp. 436-440
-
-
Della Gatta, G.1
Palomero, T.2
Perez-Garcia, A.3
-
79
-
-
84855508998
-
ETV6 mutations in early immature human T cell leukemias
-
Van Vlierberghe P., Ambesi-Impiombato A., Perez-Garcia A., et al. ETV6 mutations in early immature human T cell leukemias. J Exp Med 2011, 208(13):2571-2579.
-
(2011)
J Exp Med
, vol.208
, Issue.13
, pp. 2571-2579
-
-
Van Vlierberghe, P.1
Ambesi-Impiombato, A.2
Perez-Garcia, A.3
-
80
-
-
79956108320
-
Gain-of-function mutations in interleukin-7 receptor-alpha (IL7R) in childhood acute lymphoblastic leukemias
-
Shochat C., Tal N., Bandapalli O.R., et al. Gain-of-function mutations in interleukin-7 receptor-alpha (IL7R) in childhood acute lymphoblastic leukemias. J Exp Med 2011, 208(5):901-908.
-
(2011)
J Exp Med
, vol.208
, Issue.5
, pp. 901-908
-
-
Shochat, C.1
Tal, N.2
Bandapalli, O.R.3
-
81
-
-
80053385665
-
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
-
Zenatti P.P., Ribeiro D., Li W., et al. Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia. Nat Genet 2011, 43(10):932-939.
-
(2011)
Nat Genet
, vol.43
, Issue.10
, pp. 932-939
-
-
Zenatti, P.P.1
Ribeiro, D.2
Li, W.3
-
82
-
-
84856747744
-
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
-
Ntziachristos P., Tsirigos A., Vlierberghe P.V., et al. Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia. Nat Med 2012, 18(2):298-303.
-
(2012)
Nat Med
, vol.18
, Issue.2
, pp. 298-303
-
-
Ntziachristos, P.1
Tsirigos, A.2
Vlierberghe, P.V.3
-
83
-
-
84872851349
-
FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors
-
Neumann M., Coskun E., Fransecky L., et al. FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors. PLoS One 2013, 8(1):e53190.
-
(2013)
PLoS One
, vol.8
, Issue.1
-
-
Neumann, M.1
Coskun, E.2
Fransecky, L.3
-
84
-
-
84863966948
-
Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations
-
Neumann M., Heesch S., Gokbuget N., et al. Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations. Blood Cancer J 2012, 2(1):e55.
-
(2012)
Blood Cancer J
, vol.2
, Issue.1
-
-
Neumann, M.1
Heesch, S.2
Gokbuget, N.3
-
85
-
-
75749124332
-
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
-
Morin R.D., Johnson N.A., Severson T.M., et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet 2010, 42(2):181-185.
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 181-185
-
-
Morin, R.D.1
Johnson, N.A.2
Severson, T.M.3
-
86
-
-
78650454078
-
Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
-
Sneeringer C.J., Scott M.P., Kuntz K.W., et al. Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas. Proc Natl Acad Sci U S A 2010, 107(49):20980-20985.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.49
, pp. 20980-20985
-
-
Sneeringer, C.J.1
Scott, M.P.2
Kuntz, K.W.3
-
87
-
-
79952167230
-
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
-
Yap D.B., Chu J., Berg T., et al. Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Blood 2011, 117(8):2451-2459.
-
(2011)
Blood
, vol.117
, Issue.8
, pp. 2451-2459
-
-
Yap, D.B.1
Chu, J.2
Berg, T.3
-
88
-
-
84859295400
-
A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia
-
Simon C., Chagraoui J., Krosl J., et al. A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. Genes Dev 2012, 26(7):651-656.
-
(2012)
Genes Dev
, vol.26
, Issue.7
, pp. 651-656
-
-
Simon, C.1
Chagraoui, J.2
Krosl, J.3
-
89
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
Ley T.J., Ding L., Walter M.J., et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med 2010, 363(25):2424-2433.
-
(2010)
N Engl J Med
, vol.363
, Issue.25
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
-
90
-
-
84881041250
-
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations
-
Neumann M., Heesch S., Schlee C., et al. Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations. Blood 2013, 121(23):4749-4752.
-
(2013)
Blood
, vol.121
, Issue.23
, pp. 4749-4752
-
-
Neumann, M.1
Heesch, S.2
Schlee, C.3
-
91
-
-
84874106911
-
The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia
-
Shi J., Wang E., Zuber J., et al. The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia. Oncogene 2013, 32(7):930-938.
-
(2013)
Oncogene
, vol.32
, Issue.7
, pp. 930-938
-
-
Shi, J.1
Wang, E.2
Zuber, J.3
-
92
-
-
84859475727
-
Polycomb repressive complex 2 is required for MLL-AF9 leukemia
-
Neff T., Sinha A.U., Kluk M.J., et al. Polycomb repressive complex 2 is required for MLL-AF9 leukemia. Proc Natl Acad Sci U S A 2012, 109(13):5028-5033.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.13
, pp. 5028-5033
-
-
Neff, T.1
Sinha, A.U.2
Kluk, M.J.3
-
93
-
-
84884532954
-
Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer
-
Kim W., Bird G.H., Neff T., et al. Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. Nat Chem Biol 2013, 9(10):643-650.
-
(2013)
Nat Chem Biol
, vol.9
, Issue.10
, pp. 643-650
-
-
Kim, W.1
Bird, G.H.2
Neff, T.3
-
94
-
-
84873084751
-
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia
-
De Keersmaecker K., Atak Z.K., Li N., et al. Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia. Nat Genet 2013, 45(2):186-190.
-
(2013)
Nat Genet
, vol.45
, Issue.2
, pp. 186-190
-
-
De Keersmaecker, K.1
Atak, Z.K.2
Li, N.3
-
95
-
-
61549114444
-
Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia
-
Yang J.J., Bhojwani D., Yang W., et al. Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia. Blood 2008, 112(10):4178-4183.
-
(2008)
Blood
, vol.112
, Issue.10
, pp. 4178-4183
-
-
Yang, J.J.1
Bhojwani, D.2
Yang, W.3
-
96
-
-
67649442524
-
Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia
-
Kawamata N., Ogawa S., Seeger K., et al. Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia. Int J Oncol 2009, 34(6):1603-1612.
-
(2009)
Int J Oncol
, vol.34
, Issue.6
, pp. 1603-1612
-
-
Kawamata, N.1
Ogawa, S.2
Seeger, K.3
-
97
-
-
57149118627
-
Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia
-
Mullighan C.G., Phillips L.A., Su X., et al. Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science 2008, 322(5906):1377-1380.
-
(2008)
Science
, vol.322
, Issue.5906
, pp. 1377-1380
-
-
Mullighan, C.G.1
Phillips, L.A.2
Su, X.3
-
98
-
-
79952381408
-
CREBBP mutations in relapsed acute lymphoblastic leukaemia
-
Mullighan C.G., Zhang J., Kasper L.H., et al. CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature 2011, 471(7337):235-239.
-
(2011)
Nature
, vol.471
, Issue.7337
, pp. 235-239
-
-
Mullighan, C.G.1
Zhang, J.2
Kasper, L.H.3
-
99
-
-
84864865832
-
CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia
-
Inthal A., Zeitlhofer P., Zeginigg M., et al. CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia. Leukemia 2012, 26(8):1797-1803.
-
(2012)
Leukemia
, vol.26
, Issue.8
, pp. 1797-1803
-
-
Inthal, A.1
Zeitlhofer, P.2
Zeginigg, M.3
-
100
-
-
79952430906
-
Inactivating mutations of acetyltransferase genes in B-cell lymphoma
-
Pasqualucci L., Dominguez-Sola D., Chiarenza A., et al. Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature 2011, 471(7337):189-195.
-
(2011)
Nature
, vol.471
, Issue.7337
, pp. 189-195
-
-
Pasqualucci, L.1
Dominguez-Sola, D.2
Chiarenza, A.3
-
101
-
-
0032865411
-
Conditional modulation of glucocorticoid receptor activities by CREB-binding protein (CBP) and p300
-
Kino T., Nordeen S.K., Chrousos G.P. Conditional modulation of glucocorticoid receptor activities by CREB-binding protein (CBP) and p300. J Steroid Biochem Mol Biol 1999, 70(1-3):15-25.
-
(1999)
J Steroid Biochem Mol Biol
, vol.70
, Issue.1-3
, pp. 15-25
-
-
Kino, T.1
Nordeen, S.K.2
Chrousos, G.P.3
-
102
-
-
0037503874
-
CBP recruitment and histone acetylation in differential gene induction by glucocorticoids and progestins
-
Lambert J.R., Nordeen S.K. CBP recruitment and histone acetylation in differential gene induction by glucocorticoids and progestins. Mol Endocrinol 2003, 17(6):1085-1094.
-
(2003)
Mol Endocrinol
, vol.17
, Issue.6
, pp. 1085-1094
-
-
Lambert, J.R.1
Nordeen, S.K.2
-
103
-
-
84874663688
-
Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
-
Meyer J.A., Wang J., Hogan L.E., et al. Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia. Nat Genet 2013, 45(3):290-294.
-
(2013)
Nat Genet
, vol.45
, Issue.3
, pp. 290-294
-
-
Meyer, J.A.1
Wang, J.2
Hogan, L.E.3
-
104
-
-
84875158235
-
Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL
-
Tzoneva G., Perez-Garcia A., Carpenter Z., et al. Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL. Nat Med 2013, 19(3):368-371.
-
(2013)
Nat Med
, vol.19
, Issue.3
, pp. 368-371
-
-
Tzoneva, G.1
Perez-Garcia, A.2
Carpenter, Z.3
-
105
-
-
84871525322
-
Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia
-
Faham M., Zheng J., Moorhead M., et al. Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia. Blood 2012, 120(26):5173-5180.
-
(2012)
Blood
, vol.120
, Issue.26
, pp. 5173-5180
-
-
Faham, M.1
Zheng, J.2
Moorhead, M.3
-
106
-
-
84862013829
-
Highly sensitive MRD tests for ALL based on the IKZF1 Delta3-6 microdeletion
-
Venn N.C., van der Velden V.H., de Bie M., et al. Highly sensitive MRD tests for ALL based on the IKZF1 Delta3-6 microdeletion. Leukemia 2012, 26(6):1414-1416.
-
(2012)
Leukemia
, vol.26
, Issue.6
, pp. 1414-1416
-
-
Venn, N.C.1
van der Velden, V.H.2
de Bie, M.3
-
107
-
-
84879634027
-
Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia
-
Figueroa M.E., Chen S.C., Andersson A.K., et al. Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia. J Clin Invest 2013, 123(7):3099-3111.
-
(2013)
J Clin Invest
, vol.123
, Issue.7
, pp. 3099-3111
-
-
Figueroa, M.E.1
Chen, S.C.2
Andersson, A.K.3
-
108
-
-
84870007432
-
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia
-
Geng H., Brennan S., Milne T.A., et al. Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Cancer Discov 2012, 2(11):1004-1023.
-
(2012)
Cancer Discov
, vol.2
, Issue.11
, pp. 1004-1023
-
-
Geng, H.1
Brennan, S.2
Milne, T.A.3
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