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Volumn 115, Issue 8, 2010, Pages 1490-1499

Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: Rare clinical curios or potent genetic drivers?

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CCAAT ENHANCER BINDING PROTEIN; CYTOKINE; CYTOKINE RECEPTOR LIKE FACTOR 2; ERYTHROPOIETIN RECEPTOR; IMMUNOGLOBULIN HEAVY CHAIN; INHIBITOR OF DNA BINDING 4; NUCLEIC ACID BINDING PROTEIN; TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; CRLF2 PROTEIN, HUMAN; CYTOKINE RECEPTOR; ID4 PROTEIN, HUMAN; INHIBITOR OF DIFFERENTIATION PROTEIN; ONCOPROTEIN; TEL AML1 FUSION PROTEIN; TEL-AML1 FUSION PROTEIN;

EID: 77949910163     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-09-235986     Document Type: Article
Times cited : (50)

References (87)
  • 1
    • 34547687734 scopus 로고    scopus 로고
    • Discovery of the Philadelphia chromosome: A personal perspective
    • DOI 10.1172/JCI31771
    • Nowell PC. Discovery of the Philadelphia chromosome: a personal perspective. J Clin Invest. 2007;117(8):2033-2035. (Pubitemid 47219542)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.8 , pp. 2033-2035
    • Nowell, P.C.1
  • 2
    • 33947581390 scopus 로고    scopus 로고
    • The impact of translocations and gene fusions on cancer causation
    • DOI 10.1038/nrc2091, PII NRC2091
    • Mitelman F, Johansson B, Mertens F. The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer. 2007;7(4):233-245. (Pubitemid 46480968)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.4 , pp. 233-245
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 3
    • 0025089467 scopus 로고
    • Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome-17
    • Borrow J, Goddard AD, Sheer D, Solomon E. Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome-17. Science. 1990;249(4976):1577-1580.
    • (1990) Science , vol.249 , Issue.4976 , pp. 1577-1580
    • Borrow, J.1    Goddard, A.D.2    Sheer, D.3    Solomon, E.4
  • 4
    • 65249144557 scopus 로고    scopus 로고
    • Commonality but diversity in cancer gene fusions
    • Rabbitts TH. Commonality but diversity in cancer gene fusions. Cell. 2009;137(3):391-395.
    • (2009) Cell , vol.137 , Issue.3 , pp. 391-395
    • Rabbitts, T.H.1
  • 5
    • 0345582392 scopus 로고    scopus 로고
    • Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer
    • DOI 10.1016/S1535-6108(03)00106-5, PII S1535610803001065
    • Forster A, Pannell R, Drynan LF, et al. Engineering de novo reciprocal chromosomal translocations associated with MII to replicate primary events of human cancer. Cancer Cell. 2003;3(5):449-458. (Pubitemid 38340292)
    • (2003) Cancer Cell , vol.3 , Issue.5 , pp. 449-458
    • Forster, A.1    Pannell, R.2    Drynan, L.F.3    McCormack, M.4    Collins, E.C.5    Daser, A.6    Rabbitts, T.H.7
  • 6
    • 58149398623 scopus 로고    scopus 로고
    • Translation of the Philadelphia chromosome into therapy for CML
    • Druker BJ. Translation of the Philadelphia chromosome into therapy for CML. Blood. 2008;112(13):4808-4817.
    • (2008) Blood , vol.112 , Issue.13 , pp. 4808-4817
    • Druker, B.J.1
  • 8
    • 55549101623 scopus 로고    scopus 로고
    • DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
    • Ley TJ, Mardis ER, Ding L, et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature. 2008;456(7218):66-72.
    • (2008) Nature , vol.456 , Issue.7218 , pp. 66-72
    • Ley, T.J.1    Mardis, E.R.2    Ding, L.3
  • 9
    • 70149093912 scopus 로고    scopus 로고
    • Recurring mutations found by sequencing an acute myeloid leukemia genome
    • Mardis ER, Ding L, Dooling DJ, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med. 2009;361(11):1058- 1066.
    • (2009) N Engl J Med , vol.361 , Issue.11 , pp. 1058-1066
    • Mardis, E.R.1    Ding, L.2    Dooling, D.J.3
  • 10
    • 72049125350 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • Dang L, WhiteDW, Gross S, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009;462(7274):739-744.
    • (2009) Nature , vol.462 , Issue.7274 , pp. 739-744
    • Dang, L.1    Whitedw Gross, S.2
  • 13
    • 33751196596 scopus 로고    scopus 로고
    • Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia
    • Chapiro E, Russell L, Radford-Weiss I, et al. Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia. Blood. 2006;108(10):3560-3563.
    • (2006) Blood , vol.108 , Issue.10 , pp. 3560-3563
    • Chapiro, E.1    Russell, L.2    Radford-Weiss, I.3
  • 15
    • 38049126095 scopus 로고    scopus 로고
    • T(6;14)(p22;q32): A new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)
    • Russell LJ, Akasaka T, Majid A, et al. t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood. 2008;111(1):387-391.
    • (2008) Blood , vol.111 , Issue.1 , pp. 387-391
    • Russell, L.J.1    Akasaka, T.2    Majid, A.3
  • 16
    • 62549141516 scopus 로고    scopus 로고
    • A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin
    • Russell LJ, De Castro DG, Griffiths M, et al. A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin. Leukemia. 2009;23(3):614-617.
    • (2009) Leukemia , vol.23 , Issue.3 , pp. 614-617
    • Russell, L.J.1    De Castro, D.G.2    Griffiths, M.3
  • 17
    • 70350519430 scopus 로고    scopus 로고
    • Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B cell precursor acute lymphoblastic leukemia
    • Russell LJ, Capasso M, Vater I, et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B cell precursor acute lymphoblastic leukemia. Blood. 2009;114(13):2688-2698.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2688-2698
    • Russell, L.J.1    Capasso, M.2    Vater, I.3
  • 18
    • 0034254687 scopus 로고    scopus 로고
    • The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies
    • Willis TG, Dyer MJS. The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies. Blood. 2000;96(3):808-822. (Pubitemid 30618048)
    • (2000) Blood , vol.96 , Issue.3 , pp. 808-822
    • Willis, T.G.1    Dyer, M.J.S.2
  • 19
    • 68049086918 scopus 로고    scopus 로고
    • Chromatin architecture and the generation of antigen receptor diversity
    • Jhunjhunwala S, van Zelm MC, Peak MM, Murre C. Chromatin architecture and the generation of antigen receptor diversity. Cell. 2009;138(3):435-448.
    • (2009) Cell , vol.138 , Issue.3 , pp. 435-448
    • Jhunjhunwala, S.1    Van Zelm, M.C.2    Peak, M.M.3    Murre, C.4
  • 20
    • 0035284896 scopus 로고    scopus 로고
    • Novel control motif cluster in the IgH delta-gamma 3 interval exhibits B cell-specific enhancer function in early development
    • Mundt CA, Nicholson IC, Zou XG, Popov AV, Ayling C, Bruggemann M. Novel control motif cluster in the IgH delta-gamma 3 interval exhibits B cell-specific enhancer function in early development. J Immunol. 2001;166(5):3315-3323.
    • (2001) J Immunol , vol.166 , Issue.5 , pp. 3315-3323
    • Mundt, C.A.1    Nicholson, I.C.2    Zou, X.G.3    Popov, A.V.4    Ayling, C.5    Bruggemann, M.6
  • 21
    • 0027305991 scopus 로고
    • Unusual deletions within the immunoglobulin heavy-chain locus in acute leukemias
    • Dyer MJS, Heward JM, Zani VJ, Buccheri V, Catovsky D. Unusual deletions within the immunoglobulin heavy-chain locus in acute leukemias. Blood. 1993;82(3):865-871. (Pubitemid 23221667)
    • (1993) Blood , vol.82 , Issue.3 , pp. 865-871
    • Dyer, M.J.S.1    Heward, J.M.2    Zani, V.J.3    Buccheri, V.4    Catovsky, D.5
  • 22
    • 33750356062 scopus 로고    scopus 로고
    • Identification of cryptic aberrations and characterization of translocation breakpoints using array CGH in high hyperdiploid childhood acute lymphoblastic leukemia
    • DOI 10.1038/sj.leu.2404372, PII 2404372
    • Paulsson K, Heidenblad M, Morse H, Borg A, Fioretos T, Johansson B. Identification of cryptic aberrations and characterization of translocation breakpoints using array CGH in high hyperdiploid childhood acute lymphoblastic leukemia. Leukemia. 2006;20(11):2002-2007. (Pubitemid 44614890)
    • (2006) Leukemia , vol.20 , Issue.11 , pp. 2002-2007
    • Paulsson, K.1    Heidenblad, M.2    Morse, H.3    Borg, A.4    Fioretos, T.5    Johansson, B.6
  • 23
    • 43049139905 scopus 로고    scopus 로고
    • BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
    • Mullighan CG, Miller CB, Radtke I, et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature. 2008;453(7191):110-114.
    • (2008) Nature , vol.453 , Issue.7191 , pp. 110-114
    • Mullighan, C.G.1    Miller, C.B.2    Radtke, I.3
  • 24
    • 57149141010 scopus 로고    scopus 로고
    • Collateral damage from antigen receptor gene diversification
    • Mahowald GK, Baron JM, Sleckman BP. Collateral damage from antigen receptor gene diversification. Cell. 2008;135(6):1009-1012.
    • (2008) Cell , vol.135 , Issue.6 , pp. 1009-1012
    • Mahowald, G.K.1    Baron, J.M.2    Sleckman, B.P.3
  • 25
    • 70350680415 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 in B-progenitor- And Down syndrome-associated acute lymphoblastic leukemia
    • Mullighan CG, Collins-Underwood JR, Phillips LA, et al. Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet. 2009;41(11):1243-1246.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1243-1246
    • Mullighan, C.G.1    Collins-Underwood, J.R.2    Phillips, L.A.3
  • 26
    • 77649214639 scopus 로고    scopus 로고
    • Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: A report from the International BFM Study Group
    • Hertzberg L, Vendramini E, Ganmore I, et al. Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. Blood. 2010;115(5):1006-1017.
    • (2010) Blood , vol.115 , Issue.5 , pp. 1006-1017
    • Hertzberg, L.1    Vendramini, E.2    Ganmore, I.3
  • 27
    • 0037308761 scopus 로고    scopus 로고
    • Acute lymphoblastic leukemia characterized by t(8;14)(q11.2;q32)
    • DOI 10.1016/S0165-4608(02)00643-X, PII S016546080200643X
    • Moore S, Suttle J, Bain S, Story C, Rice M. Acute lymphoblastic leukemia characterized by t(8;14) (q11.2;q32). Cancer Genet Cytogenet. 2003;141(1):1-4. (Pubitemid 36165189)
    • (2003) Cancer Genetics and Cytogenetics , vol.141 , Issue.1 , pp. 1-4
    • Moore, S.1    Suttle, J.2    Bain, S.3    Story, C.4    Rice, M.5
  • 28
    • 57649219316 scopus 로고    scopus 로고
    • B-cell precursor t(8;14)(q11;q32)-positive acute lymphoblastic leukemia in children is strongly associated with Down syndrome or with a concomitant Philadelphia chromosome
    • Lundin C, Heldrup J, Ahlgren T, Olofsson T, Johansson B. B-cell precursor t(8;14)(q11;q32)-positive acute lymphoblastic leukemia in children is strongly associated with Down syndrome or with a concomitant Philadelphia chromosome. Eur J Haematol. 2009;82(1):46-53.
    • (2009) Eur J Haematol , vol.82 , Issue.1 , pp. 46-53
    • Lundin, C.1    Heldrup, J.2    Ahlgren, T.3    Olofsson, T.4    Johansson, B.5
  • 29
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114(5):937-951.
    • (2009) Blood , vol.114 , Issue.5 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 30
    • 27644442420 scopus 로고    scopus 로고
    • Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia [9]
    • DOI 10.1038/sj.leu.2403938, PII 2403938
    • Sonoki T, Iwanaga E, Mitsuya H, Asou N. Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia. Leukemia. 2005;19(11):2009-2010. (Pubitemid 41554016)
    • (2005) Leukemia , vol.19 , Issue.11 , pp. 2009-2010
    • Sonoki, T.1    Iwanaga, E.2    Mitsuya, H.3    Asou, N.4
  • 31
    • 0032520975 scopus 로고    scopus 로고
    • Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21
    • Willis TG, Zalcberg IR, Coignet LJA, et al. Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21. Blood. 1998;91:1873-1881.
    • (1998) Blood , vol.91 , pp. 1873-1881
    • Willis, T.G.1    Zalcberg, I.R.2    Coignet, L.J.A.3
  • 32
    • 47649124998 scopus 로고    scopus 로고
    • Novel IGHalpha translocations, t(2;14)(q14.3;q32) and t(14;17)(q32;q21), in B-cell precursor acute lymphoblastic leukemia
    • Aventin A, Sanchez J, Nomdedeu JF, et al. Novel IGHalpha translocations, t(2;14)(q14.3;q32) and t(14;17)(q32;q21), in B-cell precursor acute lymphoblastic leukemia. Cancer Genet Cytogenet. 2008;185(1):57-59.
    • (2008) Cancer Genet Cytogenet , vol.185 , Issue.1 , pp. 57-59
    • Aventin, A.1    Sanchez, J.2    Nomdedeu, J.F.3
  • 33
    • 0037173742 scopus 로고    scopus 로고
    • A novel chromosomal translocation t(1;14)(q25;q32) in pre-B acute lymphoblastic leukemia involves the LIM homeodomain protein gene, Lhx4
    • Kawamata N, Sakajiri S, Sugimoto KJ, Isobe Y, Kobayashi H, Oshimi K. A novel chromosomal translocation t(1;14)(q25;q32) in pre-B acute lymphoblastic leukemia involves the LIM homeodomain protein gene, Lhx4. Oncogene. 2002;21(32):4983-4991.
    • (2002) Oncogene , vol.21 , Issue.32 , pp. 4983-4991
    • Kawamata, N.1    Sakajiri, S.2    Sugimoto, K.J.3    Isobe, Y.4    Kobayashi, H.5    Oshimi, K.6
  • 34
    • 0346840435 scopus 로고
    • A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia
    • Pegoraro L, Palumbo A, Erikson J, et al. A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia. Proc Natl Acad Sci U S A. 1984;81(22):7166-7170.
    • (1984) Proc Natl Acad Sci U S A , vol.81 , Issue.22 , pp. 7166-7170
    • Pegoraro, L.1    Palumbo, A.2    Erikson, J.3
  • 35
    • 58149095544 scopus 로고    scopus 로고
    • Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia
    • Harrison CJ. Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia. Br J Haematol. 2009;144(2):147-156.
    • (2009) Br J Haematol , vol.144 , Issue.2 , pp. 147-156
    • Harrison, C.J.1
  • 36
    • 0035003350 scopus 로고    scopus 로고
    • The leukaemia research fund/United Kingdom Cancer Cytogenetics Group Karyotype Database in acute lymphoblastic leukaemia: A valuable resource for patient management
    • DOI 10.1046/j.1365-2141.2001.02643.x
    • Harrison CJ, Martineau M, Secker-Walker LM. The Leukaemia Research Fund/United Kingdom Cancer Cytogenetics Group karyotype database in acute lymphoblastic leukaemia: a valuable resource for patient management. Br J Haematol. 2001;113(1):3-10. (Pubitemid 32423294)
    • (2001) British Journal of Haematology , vol.113 , Issue.1 , pp. 3-10
    • Harrison, C.J.1    Martineau, M.2    Secker-Walker, L.M.3
  • 37
    • 1342303482 scopus 로고    scopus 로고
    • Of Mice and Not Men: Differences between Mouse and Human Immunology
    • Mestas J, Hughes CCW. Of mice and not men: differences between mouse and human immunology. J Immunol. 2004;172(5):2731-2738. (Pubitemid 38263654)
    • (2004) Journal of Immunology , vol.172 , Issue.5 , pp. 2731-2738
    • Mestas, J.1    Hughes, C.C.W.2
  • 38
    • 64249139290 scopus 로고    scopus 로고
    • IL-7 dependence in human B lymphopoiesis increases during progression of ontogeny from cord blood to bone marrow
    • Parrish YK, Baez I, Milford TA, et al. IL-7 dependence in human B lymphopoiesis increases during progression of ontogeny from cord blood to bone marrow. J Immunol. 2009;182(7):4255-4266.
    • (2009) J Immunol , vol.182 , Issue.7 , pp. 4255-4266
    • Parrish, Y.K.1    Baez, I.2    Milford, T.A.3
  • 39
    • 0036302048 scopus 로고    scopus 로고
    • TSLP: Finally in the limelight
    • Leonard WJ. TSLP: finally in the limelight. Nat Immunol. 2002;3(7):605-607.
    • (2002) Nat Immunol , vol.3 , Issue.7 , pp. 605-607
    • Leonard, W.J.1
  • 40
    • 0033555804 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin: A cytokine that promotes the development of IgM(+) B cells in vitro and signals via a novel mechanism
    • Levin SD, Koelling RM, Friend SL, et al. Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM(+) B cells in vitro and signals via a novel mechanism. J Immunol. 1999;162(2):677-683.
    • (1999) J Immunol , vol.162 , Issue.2 , pp. 677-683
    • Levin, S.D.1    Koelling, R.M.2    Friend, S.L.3
  • 43
    • 35448953345 scopus 로고    scopus 로고
    • Thymic stromal-derived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Ralpha signaling
    • DOI 10.1158/0008-5472.CAN-06-4704
    • Brown VI, Hulitt J, Fish J, et al. Thymic stromalderived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Ralpha signaling. Cancer Res. 2007;67(20):9963-9970. (Pubitemid 47621246)
    • (2007) Cancer Research , vol.67 , Issue.20 , pp. 9963-9970
    • Brown, V.I.1    Hulitt, J.2    Fish, J.3    Sheen, C.4    Bruno, M.5    Xu, Q.6    Carroll, M.7    Fang, J.8    Teachey, D.9    Grupp, S.A.10
  • 45
    • 67249146555 scopus 로고    scopus 로고
    • JAK mutations in high-risk childhood acute lymphoblastic leukemia
    • Mullighan CG, Zhang JH, Harvey RC, et al. JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 2009;106(23):9414-9418.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.23 , pp. 9414-9418
    • Mullighan, C.G.1    Zhang, J.H.2    Harvey, R.C.3
  • 46
    • 77950423581 scopus 로고    scopus 로고
    • Use of genomic technologies to identify novel genetic abnormalities and therapeutic targets in acute lymphoblastic leukemia
    • Willman CL, Kang HN, Harvey RC, et al. Use of genomic technologies to identify novel genetic abnormalities and therapeutic targets in acute lymphoblastic leukemia. Blood. 2008;112(11):1344-1345.
    • (2008) Blood , vol.112 , Issue.11 , pp. 1344-1345
    • Willman, C.L.1    Kang, H.N.2    Harvey, R.C.3
  • 47
    • 58149348631 scopus 로고    scopus 로고
    • Role of the erythropoietin receptor in ETV6/RUNX1-positive acute lymphoblastic leukemia
    • Inthal A, Krapf G, Beck D, et al. Role of the erythropoietin receptor in ETV6/RUNX1-positive acute lymphoblastic leukemia. Clin Cancer Res. 2008;14(22):7196-7204.
    • (2008) Clin Cancer Res , vol.14 , Issue.22 , pp. 7196-7204
    • Inthal, A.1    Krapf, G.2    Beck, D.3
  • 48
    • 35748940965 scopus 로고    scopus 로고
    • Characterization of early stages of human B cell development by gene expression profiling
    • Hystad ME, Myklebust JH, Bo TH, et al. Characterization of early stages of human B cell development by gene expression profiling. J Immunol. 2007;179(6):3662-3671.
    • (2007) J Immunol , vol.179 , Issue.6 , pp. 3662-3671
    • Hystad, M.E.1    Myklebust, J.H.2    Bo, T.H.3
  • 49
    • 65249178875 scopus 로고    scopus 로고
    • The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells
    • Ford AM, Palmi C, Bueno C, et al. The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells. J Clin Invest. 2009;119(4):826-836.
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 826-836
    • Ford, A.M.1    Palmi, C.2    Bueno, C.3
  • 50
    • 70249134095 scopus 로고    scopus 로고
    • Erythroid-stimulating agents in cancer therapy: Potential dangers and biologic mechanisms
    • Hadland BK, Longmore GD. Erythroid-stimulating agents in cancer therapy: potential dangers and biologic mechanisms. J Clin Oncol. 2009;27(25):4217-4226.
    • (2009) J Clin Oncol , vol.27 , Issue.25 , pp. 4217-4226
    • Hadland, B.K.1    Longmore, G.D.2
  • 51
    • 2942627112 scopus 로고    scopus 로고
    • A 12-year-old boy with fatigue and eosinophilia: Precursor B-cell acute lymphoblastic leukemia with eosinophilia and the t(5;14)(q31;q32) translocation
    • Huang MS, Harris NL, D'Angelo HA, Hasserjian RP, Weinstein H. A 12-year-old boy with fatigue and eosinophilia: precursor B-cell acute lymphoblastic leukemia with eosinophilia and the t(5;14)(q31;q32) translocation. N Engl J Med. 2004;350(25):2604-2612.
    • (2004) N Engl J Med , vol.350 , Issue.25 , pp. 2604-2612
    • Huang, M.S.1    Harris, N.L.2    D'Angelo, H.A.3    Hasserjian, R.P.4    Weinstein, H.5
  • 52
    • 0028335141 scopus 로고
    • The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3
    • Riechmann V, van Cruchten I, Sablitzky F. The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. Nucleic Acids Res. 1994;22(5):749-755. (Pubitemid 24160899)
    • (1994) Nucleic Acids Research , vol.22 , Issue.5 , pp. 749-755
    • Riechmann, V.1    Van Cruchten, I.2    Sablitzky, F.3
  • 53
    • 0035169904 scopus 로고    scopus 로고
    • Id helix-loop-helix proteins antagonize Pax transcription factor activity by inhibiting DNA binding
    • DOI 10.1128/MCB.21.2.524-533.2001
    • Roberts EC, Deed RW, Inoue T, Norton JD, Sharrocks AD. Id helix-loop-helix proteins antagonize Pax transcription factor activity by inhibiting DNA binding. Mol Cell Biol. 2001;21(2):524-533. (Pubitemid 32037372)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.2 , pp. 524-533
    • Roberts, E.C.1    Deed, R.W.2    Inoue, T.3    Norton, J.D.4    Sharrocks, A.D.5
  • 54
    • 61349152914 scopus 로고    scopus 로고
    • E and ID proteins branch out
    • Kee BL. E and ID proteins branch out. Nat Rev Immunol. 2009;9(3):175-184.
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 175-184
    • Kee, B.L.1
  • 56
    • 48749083583 scopus 로고    scopus 로고
    • Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin e and notch signaling
    • Jeon HM, Jin X, Lee JS, et al. Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling. Genes Dev. 2008;22(15):2028-2033.
    • (2008) Genes Dev , vol.22 , Issue.15 , pp. 2028-2033
    • Jeon, H.M.1    Jin, X.2    Lee, J.S.3
  • 57
    • 0030967342 scopus 로고    scopus 로고
    • Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system
    • Cooper CL, Brady G, Bilia F, Iscove NN, Quesenberry PJ. Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system. Blood. 1997;89(9):3155-3165. (Pubitemid 27229798)
    • (1997) Blood , vol.89 , Issue.9 , pp. 3155-3165
    • Cooper, C.L.1    Brady, G.2    Bilia, F.3    Iscove, N.N.4    Quesenberry, P.J.5
  • 60
    • 33751160409 scopus 로고    scopus 로고
    • ID proteins as targets in cancer and tools in neurobiology
    • Iavarone A, Lasorella A. ID proteins as targets in cancer and tools in neurobiology. Trends Mol Med. 2006;12(12):588-594.
    • (2006) Trends Mol Med , vol.12 , Issue.12 , pp. 588-594
    • Iavarone, A.1    Lasorella, A.2
  • 61
    • 38049094661 scopus 로고    scopus 로고
    • Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo
    • Henke E, Perk J, Vider J, et al. Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo. Nat Biotechnol. 2008;26(1):91-100.
    • (2008) Nat Biotechnol , vol.26 , Issue.1 , pp. 91-100
    • Henke, E.1    Perk, J.2    Vider, J.3
  • 62
    • 0035525788 scopus 로고    scopus 로고
    • Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies
    • Sonoki T, Harder L, Horsman DE, et al. Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies. Blood. 2001;98(9):2837-2844.
    • (2001) Blood , vol.98 , Issue.9 , pp. 2837-2844
    • Sonoki, T.1    Harder, L.2    Horsman, D.E.3
  • 64
    • 14944358752 scopus 로고    scopus 로고
    • C/EBPdelta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation
    • DOI 10.1038/sj.onc.1208393
    • Gery S, Tanosaki S, Hofmann WK, Koppel A, Koeffler HP. C/EBP delta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation. Oncogene. 2005;24(9):1589-1597. (Pubitemid 40396088)
    • (2005) Oncogene , vol.24 , Issue.9 , pp. 1589-1597
    • Gery, S.1    Tanosaki, S.2    Hofmann, W.-K.3    Koppel, A.4    Koeffler, H.P.5
  • 65
    • 34547133494 scopus 로고    scopus 로고
    • The C/EBP family of transcription factors: A paradigm for interaction between gene expression and proliferation control
    • Nerlov C. The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control. Trends Cell Biol. 2007;17(7):318-324.
    • (2007) Trends Cell Biol , vol.17 , Issue.7 , pp. 318-324
    • Nerlov, C.1
  • 66
    • 10344230611 scopus 로고    scopus 로고
    • Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha
    • Zhang P, Iwasaki-Arai J, Iwasaki H, et al. Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. Immunity. 2004;21(6):853-863.
    • (2004) Immunity , vol.21 , Issue.6 , pp. 853-863
    • Zhang, P.1    Iwasaki-Arai, J.2    Iwasaki, H.3
  • 67
    • 2542455620 scopus 로고    scopus 로고
    • Stepwise reprogramming of B cells into macrophages
    • Xie HF, Ye M, Feng R, Graf T. Stepwise reprogramming of B cells into macrophages. Cell. 2004;117(5):663-676.
    • (2004) Cell , vol.117 , Issue.5 , pp. 663-676
    • Xie, H.F.1    Ye, M.2    Feng, R.3    Graf, T.4
  • 68
    • 33644641356 scopus 로고    scopus 로고
    • Determinants of lymphoid-myeloid lineage diversification
    • Laiosa CV, Stadtfeld M, Graf T. Determinants of lymphoid-myeloid lineage diversification. Annu Rev Immunol. 2006;24:705-738.
    • (2006) Annu Rev Immunol , vol.24 , pp. 705-738
    • Laiosa, C.V.1    Stadtfeld, M.2    Graf, T.3
  • 69
    • 59149096563 scopus 로고    scopus 로고
    • Dysregulation of the C/EBP alpha differentiation pathway in human cancer
    • Koschmieder S, Halmos B, Levantini E, Tenen DG. Dysregulation of the C/EBP alpha differentiation pathway in human cancer. J Clin Oncol. 2009;27(4):619-628.
    • (2009) J Clin Oncol , vol.27 , Issue.4 , pp. 619-628
    • Koschmieder, S.1    Halmos, B.2    Levantini, E.3    Tenen, D.G.4
  • 71
    • 0036340784 scopus 로고    scopus 로고
    • BCR-ABL suppresses C/EBP alpha expression through inhibitory action of hnRNP E2
    • Perrotti D, Cesi V, Trotta R, et al. BCR-ABL suppresses C/EBP alpha expression through inhibitory action of hnRNP E2. Nat Genet. 2002;30(1):48-58.
    • (2002) Nat Genet , vol.30 , Issue.1 , pp. 48-58
    • Perrotti, D.1    Cesi, V.2    Trotta, R.3
  • 72
    • 33846622099 scopus 로고    scopus 로고
    • Transcription factors in myeloid development: Balancing differentiation with transformation
    • DOI 10.1038/nri2024, PII NRI2024
    • Rosenbauer F, Tenen DG. Transcription factors in myeloid development: balancing differentiation with transformation. Nat Rev Immunol. 2007;7(2):105-117. (Pubitemid 46174858)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.2 , pp. 105-117
    • Rosenbauer, F.1    Tenen, D.G.2
  • 73
    • 69349101565 scopus 로고    scopus 로고
    • Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia
    • Papaemmanuil E, Hosking FJ, Vijayakrishnan J, et al. Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat Genet. 2009;41(9):1006-1010.
    • (2009) Nat Genet , vol.41 , Issue.9 , pp. 1006-1010
    • Papaemmanuil, E.1    Hosking, F.J.2    Vijayakrishnan, J.3
  • 74
    • 58149145653 scopus 로고    scopus 로고
    • Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation
    • Bousquet M, Quelen C, Rosati R, et al. Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation. J Exp Med. 2008;205(11):2499-2506.
    • (2008) J Exp Med , vol.205 , Issue.11 , pp. 2499-2506
    • Bousquet, M.1    Quelen, C.2    Rosati, R.3
  • 75
    • 64349101658 scopus 로고    scopus 로고
    • MicroRNA-125b is a novel negative regulator of p53
    • Le MTN, Teh C, Shyh-Chang N, et al. MicroRNA-125b is a novel negative regulator of p53. Genes Dev. 2009;23(7):862-876.
    • (2009) Genes Dev , vol.23 , Issue.7 , pp. 862-876
    • Le, M.T.N.1    Teh, C.2    Shyh-Chang, N.3
  • 76
    • 65549112644 scopus 로고    scopus 로고
    • Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas
    • Malumbres R, Sarosiek KA, Cubedo E, et al. Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas. Blood. 2009;113(16):3754-3764.
    • (2009) Blood , vol.113 , Issue.16 , pp. 3754-3764
    • Malumbres, R.1    Sarosiek, K.A.2    Cubedo, E.3
  • 77
    • 63149148538 scopus 로고    scopus 로고
    • Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome
    • Malinge S, Izraeli S, Crispino JD. Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome. Blood. 2009;113(12):2619-2628.
    • (2009) Blood , vol.113 , Issue.12 , pp. 2619-2628
    • Malinge, S.1    Izraeli, S.2    Crispino, J.D.3
  • 78
    • 77950379123 scopus 로고    scopus 로고
    • Chromosome 21-encoded miR-125b and its role in the development of myeloid leukemia in children with Down's syndrome [abstract]
    • Klusmann JH, Janikova K, Li Z, Orkin SH, Reinhardt D. Chromosome 21-encoded miR-125b and its role in the development of myeloid leukemia in children with Down's syndrome [abstract]. Blood. 2007;110(11):220.
    • (2007) Blood , vol.110 , Issue.11 , pp. 220
    • Klusmann, J.H.1    Janikova, K.2    Li, Z.3    Orkin, S.H.4    Reinhardt, D.5
  • 79
    • 74249103042 scopus 로고    scopus 로고
    • Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53
    • Gefen N, Binder V, Zaliova M, et al. Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53. Leukemia. 2010;24(1):89-96.
    • (2010) Leukemia , vol.24 , Issue.1 , pp. 89-96
    • Gefen, N.1    Binder, V.2    Zaliova, M.3
  • 80
    • 1642541155 scopus 로고    scopus 로고
    • Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia
    • DOI 10.1182/blood-2003-05-1518
    • Fine BM, Stanulla M, Schrappe M, et al. Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia. Blood. 2004;103(3):1043-1049. (Pubitemid 38129570)
    • (2004) Blood , vol.103 , Issue.3 , pp. 1043-1049
    • Fine, B.M.1    Stanulla, M.2    Schrappe, M.3    Ho, M.4    Viehmann, S.5    Harbott, J.6    Boxer, L.M.7
  • 81
    • 40749150603 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia
    • Pui CH, Robison LL, Look AT. Acute lymphoblastic leukaemia. Lancet. 2008;371(9617):1030-1043.
    • (2008) Lancet , vol.371 , Issue.9617 , pp. 1030-1043
    • Pui, C.H.1    Robison, L.L.2    Look, A.T.3
  • 82
    • 43249100129 scopus 로고    scopus 로고
    • Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin
    • Sustmann C, Flach H, Ebert H, Eastman Q, Grosschedl R. Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin. Mol Cell Biol. 2008;28(10):3526-3537.
    • (2008) Mol Cell Biol , vol.28 , Issue.10 , pp. 3526-3537
    • Sustmann, C.1    Flach, H.2    Ebert, H.3    Eastman, Q.4    Grosschedl, R.5
  • 85
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3′ UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr C, Bartel DP. Widespread shortening of 3′ UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell. 2009;138(4):673-684.
    • (2009) Cell , vol.138 , Issue.4 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 86
    • 0031024647 scopus 로고    scopus 로고
    • Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors
    • DOI 10.1093/emboj/16.2.332
    • Hara E, Hall M, Peters G. Cdk2-dependent phosphorylation of Id2 modulates activity of E2A-related transcription factors. EMBO J. 1997;16(2):332-342. (Pubitemid 27049390)
    • (1997) EMBO Journal , vol.16 , Issue.2 , pp. 332-342
    • Hara, E.1    Hall, M.2    Peters, G.3
  • 87
    • 0036510386 scopus 로고    scopus 로고
    • Contribution of the helix-loop-helix factor Id2 to regulation of vascular smooth muscle cell proliferation
    • Matsumura ME, Lobe DR, McNamara CA. Contribution of the helix-loop-helix factor Id2 to regulation of vascular smooth muscle cell proliferation. J Biol Chem. 2002;277(9):7293-7297.
    • (2002) J Biol Chem , vol.277 , Issue.9 , pp. 7293-7297
    • Matsumura, M.E.1    Lobe, D.R.2    McNamara, C.A.3


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