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Volumn 120, Issue 6, 2010, Pages 2058-2069

Lnk constrains myeloproliferative diseases in mice

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BCR ABL PROTEIN; CYTOKINE; PROTEIN LNK; UNCLASSIFIED DRUG;

EID: 77953193307     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI42032     Document Type: Article
Times cited : (90)

References (43)
  • 2
    • 0029171091 scopus 로고
    • Structure and function of the cytokine receptor superfamily
    • Drachman JG, Kaushansky K. Structure and function of the cytokine receptor superfamily. Curr Opin Hematol. 1995;2(1):22-28.
    • (1995) Curr Opin Hematol , vol.2 , Issue.1 , pp. 22-28
    • Drachman, J.G.1    Kaushansky, K.2
  • 3
    • 0042203565 scopus 로고    scopus 로고
    • SH2 and PTB domains in tyrosine kinase signaling
    • Schlessinger J, Lemmon MA. SH2 and PTB domains in tyrosine kinase signaling. Sci STKE. 2003;2003(191):RE12.
    • (2003) Sci STKE , vol.2003 , Issue.191
    • Schlessinger, J.1    Lemmon, M.A.2
  • 4
    • 0035811366 scopus 로고    scopus 로고
    • Lnk adaptor: Novel negative regulator of B cell lymphopoiesis
    • Rudd CE. Lnk adaptor: novel negative regulator of B cell lymphopoiesis. Sci STKE. 2001;2001(85):pe1.
    • (2001) Sci STKE , vol.2001 , Issue.85
    • Rudd, C.E.1
  • 5
    • 0033637359 scopus 로고    scopus 로고
    • Control of B cell production by the adaptor protein lnk. Definition of a conserved family of signal-modulating proteins
    • Takaki S, et al. Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins. Immunity. 2000;13(5):599-609.
    • (2000) Immunity , vol.13 , Issue.5 , pp. 599-609
    • Takaki, S.1
  • 8
    • 48749084130 scopus 로고    scopus 로고
    • Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2
    • Bersenev A, Wu C, Balcerek J, Tong W. Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2. J Clin Invest. 2008;118(8):2832-2844.
    • (2008) J Clin Invest , vol.118 , Issue.8 , pp. 2832-2844
    • Bersenev, A.1    Wu, C.2    Balcerek, J.3    Tong, W.4
  • 10
    • 4544277651 scopus 로고    scopus 로고
    • Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis
    • DOI 10.1084/jem.20040762
    • Tong W, Lodish HF. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. J Exp Med. 2004;200(5):569-580. (Pubitemid 39258306)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.5 , pp. 569-580
    • Tong, W.1    Lodish, H.F.2
  • 12
    • 0001639195 scopus 로고
    • Some speculations on the myeloproliferative syndromes
    • Dameshek W. Some speculations on the myeloproliferative syndromes. Blood. 1951;6(4):372-375.
    • (1951) Blood , vol.6 , Issue.4 , pp. 372-375
    • Dameshek, W.1
  • 13
    • 33947328520 scopus 로고    scopus 로고
    • Oncogenes in myeloproliferative disorders
    • Tefferi A, Gilliland DG. Oncogenes in myeloproliferative disorders. Cell Cycle. 2007;6(5):550-566.
    • (2007) Cell Cycle , vol.6 , Issue.5 , pp. 550-566
    • Tefferi, A.1    Gilliland, D.G.2
  • 18
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7(4):387-397.
    • (2005) Cancer Cell , vol.7 , Issue.4 , pp. 387-397
    • Levine, R.L.1
  • 19
    • 67149083222 scopus 로고    scopus 로고
    • Lnk inhibits myeloproliferative disorderassociated JAK2 mutant JAK2V617F
    • Gery S, Cao Q, Gueller S, Xing H, Tefferi A, Koeffler HP. Lnk inhibits myeloproliferative disorderassociated JAK2 mutant, JAK2V617F. J Leukoc Biol. 2009;85(6):957-965.
    • (2009) J Leukoc Biol , vol.85 , Issue.6 , pp. 957-965
    • Gery, S.1    Cao, Q.2    Gueller, S.3    Xing, H.4    Tefferi, A.5    Koeffler, H.P.6
  • 20
    • 36148995898 scopus 로고    scopus 로고
    • Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders
    • Gery S, Gueller S, Chumakova K, Kawamata N, Liu L, Koeffler HP. Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders. Blood. 2007;110(9):3360-3364.
    • (2007) Blood , vol.110 , Issue.9 , pp. 3360-3364
    • Gery, S.1    Gueller, S.2    Chumakova, K.3    Kawamata, N.4    Liu, L.5    Koeffler, H.P.6
  • 21
    • 35348849015 scopus 로고    scopus 로고
    • Hox genes in hematopoiesis and leukemogenesis
    • Argiropoulos B, Humphries RK. Hox genes in hematopoiesis and leukemogenesis. Oncogene. 2007;26(47):6766-6776.
    • (2007) Oncogene , vol.26 , Issue.47 , pp. 6766-6776
    • Argiropoulos, B.1    Humphries, R.K.2
  • 22
    • 33644843788 scopus 로고    scopus 로고
    • Zinc-finger transcription factor Gfi-1: Versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells
    • PII 0006275220060100000002
    • Hock H, Orkin SH. Zinc-finger transcription factor Gfi-1: versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells. Curr Opin Hematol. 2006;13(1):1-6. (Pubitemid 43755839)
    • (2006) Current Opinion in Hematology , vol.13 , Issue.1 , pp. 1-6
    • Hock, H.1    Orkin, S.H.2
  • 23
    • 35548934558 scopus 로고    scopus 로고
    • MLL translocations, histone modifications and leukaemia stem-cell development
    • Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer. 2007;7(11):823-833.
    • (2007) Nat Rev Cancer , vol.7 , Issue.11 , pp. 823-833
    • Krivtsov, A.V.1    Armstrong, S.A.2
  • 24
    • 33746459740 scopus 로고    scopus 로고
    • Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors
    • DOI 10.1101/sqb.2005.70.057
    • Pardal R, Molofsky AV, He S, Morrison SJ. Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors. Cold Spring Harb Symp Quant Biol. 2005;70:177-185. (Pubitemid 44124870)
    • (2005) Cold Spring Harbor Symposia on Quantitative Biology , vol.70 , pp. 177-185
    • Pardal, R.1    Molofsky, A.V.2    He, S.3    Morrison, S.J.4
  • 25
    • 33646057653 scopus 로고    scopus 로고
    • Pten, tumorigenesis, and stem cell self-renewal
    • Rossi DJ, Weissman IL. Pten, tumorigenesis, and stem cell self-renewal. Cell. 2006;125(2):229-231.
    • (2006) Cell , vol.125 , Issue.2 , pp. 229-231
    • Rossi, D.J.1    Weissman, I.L.2
  • 27
    • 22344437262 scopus 로고    scopus 로고
    • Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow
    • DOI 10.1084/jem.20041419
    • Ueda Y, Kondo M, Kelsoe G. Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow. J Exp Med. 2005;201(11):1771-1780. (Pubitemid 41002896)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.11 , pp. 1771-1780
    • Ueda, Y.1    Kondo, M.2    Kelsoe, G.3
  • 28
    • 0037968549 scopus 로고    scopus 로고
    • Gene expression analysis of purified hematopoietic stem cells and committed progenitors
    • DOI 10.1182/blood-2002-08-2509
    • Terskikh AV, Miyamoto T, Chang C, Diatchenko L, Weissman IL. Gene expression analysis of purified hematopoietic stem cells and committed progenitors. Blood. 2003;102(1):94-101. (Pubitemid 36759641)
    • (2003) Blood , vol.102 , Issue.1 , pp. 94-101
    • Terskikh, A.V.1    Miyamoto, T.2    Chang, C.3    Diatchenko, L.4    Weissman, I.L.5
  • 29
    • 20444426803 scopus 로고    scopus 로고
    • Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways
    • DOI 10.1182/blood-2004-10-4093
    • Tong W, Zhang J, Lodish HF. Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways. Blood. 2005;105(12):4604- 4612. (Pubitemid 40807278)
    • (2005) Blood , vol.105 , Issue.12 , pp. 4604-4612
    • Tong, W.1    Zhang, J.2    Lodish, H.F.3
  • 30
    • 33744490974 scopus 로고    scopus 로고
    • Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
    • DOI 10.1182/blood-2005-12-4824
    • Wernig G, Mercher T, Okabe R, Levine RL, Lee BH, Gilliland DG. Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood. 2006;107(11):4274-4281. (Pubitemid 43801351)
    • (2006) Blood , vol.107 , Issue.11 , pp. 4274-4281
    • Wernig, G.1    Mercher, T.2    Okabe, R.3    Levine, R.L.4    Lee, B.H.5    Gilliland, D.G.6
  • 31
    • 33745721197 scopus 로고    scopus 로고
    • V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis
    • DOI 10.1182/blood-2006-02-002030
    • Lacout C, Pisani DF, Tulliez M, Gachelin FM, Vainchenker W, Villeval JL. JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis. Blood. 2006;108(5):1652-1660. (Pubitemid 44316134)
    • (2006) Blood , vol.108 , Issue.5 , pp. 1652-1660
    • Lacout, C.1    Pisani, D.F.2    Tulliez, M.3    Gachelin, F.M.4    Vainchenker, W.5    Villeval, J.-L.6
  • 33
    • 0028956353 scopus 로고
    • Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
    • Klingmuller U, Lorenz U, Cantley LC, Neel BG, Lodish HF. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell. 1995;80(5):729-738.
    • (1995) Cell , vol.80 , Issue.5 , pp. 729-738
    • Klingmuller, U.1    Lorenz, U.2    Cantley, L.C.3    Neel, B.G.4    Lodish, H.F.5
  • 34
    • 42149188212 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells
    • DOI 10.1101/gad.1651408
    • Rathinam C, Thien CB, Langdon WY, Gu H, Flavell RA. The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells. Genes Dev. 2008;22(8):992-997. (Pubitemid 351544238)
    • (2008) Genes and Development , vol.22 , Issue.8 , pp. 992-997
    • Rathinam, C.1    Thien, C.B.F.2    Langdon, W.Y.3    Gu, H.4    Flavell, R.A.5
  • 35
    • 68949124841 scopus 로고    scopus 로고
    • Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms
    • Sanada M, et al. Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. Nature. 2009;460(7257):904-908.
    • (2009) Nature , vol.460 , Issue.7257 , pp. 904-908
    • Sanada, M.1
  • 36
    • 0041302153 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling and inflammatory diseases
    • DOI 10.1016/S1471-4892(03)00070-5, PII S1471489203000705
    • Inagaki-Ohara K, Hanada T, Yoshimura A. Negative regulation of cytokine signaling and inflammatory diseases. Curr Opin Pharmacol. 2003;3(4):435-442. (Pubitemid 36908948)
    • (2003) Current Opinion in Pharmacology , vol.3 , Issue.4 , pp. 435-442
    • Inagaki-Ohara, K.1    Hanada, T.2    Yoshimura, A.3
  • 37
    • 0033828672 scopus 로고    scopus 로고
    • SOCS: Physiological suppressors of cytokine signaling
    • Krebs DL, Hilton DJ. SOCS: physiological suppressors of cytokine signaling. J Cell Sci. 2000; 113(pt 16):2813-2819.
    • (2000) J Cell Sci , vol.113 , Issue.PART 16 , pp. 2813-2819
    • Krebs, D.L.1    Hilton, D.J.2
  • 38
    • 73949142609 scopus 로고    scopus 로고
    • Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- Cell population with intrinsic resistance to imatinib
    • Lemoli RM, et al. Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib. Blood. 2009;114(25):5191- 5200.
    • (2009) Blood , vol.114 , Issue.25 , pp. 5191-5200
    • Lemoli, R.M.1
  • 39
    • 70449726874 scopus 로고    scopus 로고
    • Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome
    • Will B, et al. Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome. Blood. 2009;114(18):3899-3908.
    • (2009) Blood , vol.114 , Issue.18 , pp. 3899-3908
    • Will, B.1
  • 41
    • 19944385935 scopus 로고    scopus 로고
    • MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
    • Huntly BJ, et al. MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. Cancer Cell. 2004;6(6):587-596.
    • (2004) Cancer Cell , vol.6 , Issue.6 , pp. 587-596
    • Huntly, B.J.1
  • 42
    • 0036463950 scopus 로고    scopus 로고
    • Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia
    • DOI 10.1016/S1535-6108(02)00016-8
    • Higuchi M, O'Brien D, Kumaravelu P, Lenny N, Yeoh EJ, Downing JR. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia. Cancer Cell. 2002;1(1):63-74. (Pubitemid 41039177)
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 63-74
    • Higuchi, M.1    O'Brien, D.2    Kumaravelu, P.3    Lenny, N.4    Yeoh, E.-J.5    Downing, J.R.6
  • 43
    • 0030791974 scopus 로고    scopus 로고
    • Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL
    • DOI 10.1093/emboj/16.14.4226
    • Lavau C, Szilvassy SJ, Slany R, Cleary ML. Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL. EMBO J. 1997;16(14):4226-4237. (Pubitemid 27298175)
    • (1997) EMBO Journal , vol.16 , Issue.14 , pp. 4226-4237
    • Lavau, C.1    Szilvassy, S.J.2    Slany, R.3    Cleary, M.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.