메뉴 건너뛰기




Volumn 118, Issue 11, 2011, Pages 3080-3087

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: A report from the Children's Oncology Group

(20)  Zhang, Jinghui a   Mullighan, Charles G a   Harvey, Richard C b   Wu, Gang a   Chen, Xiang a   Edmonson, Michael c   Buetow, Kenneth H c   Carroll, William L d   Chen, I Ming b   Devidas, Meenakshi e   Gerhard, Daniela S c   Loh, Mignon L f   Reaman, Gregory H g   Relling, Mary V a   Camitta, Bruce M h   Bowman, W Paul i   Smith, Malcolm A c   Willman, Cheryl L b   Downing, James R a   Hunger, Stephen P j,k  


Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; JANUS KINASE; MUCIN 4; PROTEIN P53; RAS PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR ERG; TRANSCRIPTION FACTOR ETV6;

EID: 80052922387     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-03-341412     Document Type: Article
Times cited : (225)

References (49)
  • 1
    • 76749102418 scopus 로고    scopus 로고
    • Longterm results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000
    • Moricke A, Zimmermann M, Reiter A, et al. Longterm results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000. Leukemia. 2010;24(2):265-284.
    • (2010) Leukemia , vol.24 , Issue.2 , pp. 265-284
    • Moricke, A.1    Zimmermann, M.2    Reiter, A.3
  • 2
    • 76749108960 scopus 로고    scopus 로고
    • Longterm results of the Pediatric Oncology Group Studies for Childhood Acute Lymphoblastic Leukemia 1984-2001: A report from the Children's Oncology Group
    • Salzer WL, Devidas M, Carroll WL, et al. Longterm results of the Pediatric Oncology Group Studies for Childhood Acute Lymphoblastic Leukemia 1984-2001: a report from the Children's Oncology Group. Leukemia. 2010;24(2):355-370.
    • (2010) Leukemia , vol.24 , Issue.2 , pp. 355-370
    • Salzer, W.L.1    Devidas, M.2    Carroll, W.L.3
  • 3
    • 57849138262 scopus 로고    scopus 로고
    • Factors influencing survival after relapse from acute lymphoblastic leukemia: A Children's Oncology Group study
    • Nguyen K, Devidas M, Cheng SC, et al. Factors influencing survival after relapse from acute lymphoblastic leukemia: a Children's Oncology Group study. Leukemia. 2008;22(12):2142-2150.
    • (2008) Leukemia , vol.22 , Issue.12 , pp. 2142-2150
    • Nguyen, K.1    Devidas, M.2    Cheng, S.C.3
  • 4
    • 70449711127 scopus 로고    scopus 로고
    • Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: A Children's Oncology Group study
    • Schultz KR, Bowman WP, Aledo A, et al. Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a Children's Oncology Group study. J Clin Oncol. 2009;27(31):5175-5181.
    • (2009) J Clin Oncol , vol.27 , Issue.31 , pp. 5175-5181
    • Schultz, K.R.1    Bowman, W.P.2    Aledo, A.3
  • 5
    • 58749109707 scopus 로고    scopus 로고
    • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
    • Mullighan CG, Su X, Zhang J, et al. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med. 2009;360:470-480.
    • (2009) N Engl J Med , vol.360 , pp. 470-480
    • Mullighan, C.G.1    Su, X.2    Zhang, J.3
  • 6
    • 67249146555 scopus 로고    scopus 로고
    • JAK mutations in high-risk childhood acute lymphoblastic leukemia
    • Mullighan CG, Zhang J, Harvey RC, et al. JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 2009;106:9414-9418.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9414-9418
    • Mullighan, C.G.1    Zhang, J.2    Harvey, R.C.3
  • 7
    • 77954516863 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/ Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
    • Harvey RC, Mullighan CG, Chen IM, et al. Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/ Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. Blood. 2010;115(26):5312-5321.
    • (2010) Blood , vol.115 , Issue.26 , pp. 5312-5321
    • Harvey, R.C.1    Mullighan, C.G.2    Chen, I.M.3
  • 8
    • 78649742010 scopus 로고    scopus 로고
    • Identification of novel cluster groups in pediatric highrisk B-precursor acute lymphoblastic leukemia with gene expression profiling: Correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome
    • Harvey RC, Mullighan CG, Wang X, et al. Identification of novel cluster groups in pediatric highrisk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome. Blood. 2010; 116(23):4874-4884.
    • (2010) Blood , vol.116 , Issue.23 , pp. 4874-4884
    • Harvey, R.C.1    Mullighan, C.G.2    Wang, X.3
  • 9
    • 77954659221 scopus 로고    scopus 로고
    • IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL
    • Kuiper RP, Waanders E, van der Velden VH, et al. IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL. Leukemia. 2010;24(7):1258-1264.
    • (2010) Leukemia , vol.24 , Issue.7 , pp. 1258-1264
    • Kuiper, R.P.1    Waanders, E.2    Van Der Velden, V.H.3
  • 10
    • 58749097408 scopus 로고    scopus 로고
    • Asubtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: A genomewide classification study
    • Den Boer ML, van Slegtenhorst M, De Menezes RX, et al.Asubtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genomewide classification study. Lancet Oncol. 2009;10(2):125-134.
    • (2009) Lancet Oncol , vol.10 , Issue.2 , pp. 125-134
    • Den Boer, M.L.1    Van Slegtenhorst, M.2    De Menezes, R.X.3
  • 11
    • 70350519430 scopus 로고    scopus 로고
    • Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
    • Russell LJ, Capasso M, Vater I, et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood. 2009;114(13):2688-2698.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2688-2698
    • Russell, L.J.1    Capasso, M.2    Vater, I.3
  • 12
    • 70350680415 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 in B-progenitor- And Down syndrome-associated acute lymphoblastic leukemia
    • Mullighan CG, Collins-Underwood JR, Phillips LA, et al. Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet. 2009;41(11):1243-1246.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1243-1246
    • Mullighan, C.G.1    Collins-Underwood, J.R.2    Phillips, L.A.3
  • 13
    • 54349086521 scopus 로고    scopus 로고
    • Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome
    • Bercovich D, Ganmore I, Scott LM, et al. Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome. Lancet. 2008;372(9648):1484-1492.
    • (2008) Lancet , vol.372 , Issue.9648 , pp. 1484-1492
    • Bercovich, D.1    Ganmore, I.2    Scott, L.M.3
  • 16
    • 79961191931 scopus 로고    scopus 로고
    • Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: Results of Children's Oncology Group trial P9906
    • Bowman WP, Larsen EL, Devidas M, et al. Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: Results of Children's Oncology Group trial P9906. Pediatr Blood Cancer. 2011;57(4):569-577.
    • (2011) Pediatr Blood Cancer , vol.57 , Issue.4 , pp. 569-577
    • Bowman, W.P.1    Larsen, E.L.2    Devidas, M.3
  • 18
    • 79952381408 scopus 로고    scopus 로고
    • CREBBP mutations in relapsed acute lymphoblastic leukaemia
    • Mullighan CG, Zhang J, Kasper LH, et al. CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature. 2011;471(7337):235-239.
    • (2011) Nature , vol.471 , Issue.7337 , pp. 235-239
    • Mullighan, C.G.1    Zhang, J.2    Kasper, L.H.3
  • 19
    • 0031955518 scopus 로고    scopus 로고
    • Base-calling of automated sequencer traces using phred. I. Accuracy assessment
    • Ewing B, Hillier L, Wendl MC, Green P. Basecalling of automated sequencer traces using phred: I. Accuracy assessment. Genome Res. 1998;8(3):175-185. (Pubitemid 28177229)
    • (1998) Genome Research , vol.8 , Issue.3 , pp. 175-185
    • Ewing, B.1    Hillier, L.2    Wendl, M.C.3    Green, P.4
  • 20
    • 34548084253 scopus 로고    scopus 로고
    • SNPdetector: A software tool for sensitive and accurate SNP detection
    • Zhang J, Wheeler DA, Yakub I, et al. SNPdetector: a software tool for sensitive and accurate SNP detection. PLoS Comput Biol. 2005;1(5): e53.
    • (2005) PLoS Comput Biol , vol.1 , Issue.5
    • Zhang, J.1    Wheeler, D.A.2    Yakub, I.3
  • 23
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455(7216):1061-1068.
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1061-1068
  • 24
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B. 1995;57:289-300.
    • (1995) J R Stat Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 26
    • 0034762778 scopus 로고    scopus 로고
    • Analysis of TP53 mutations in relapsed childhood acute lymphoblastic leukemia
    • DOI 10.1097/00043426-200110000-00005
    • Gump J, McGavran L, Wei Q, Hunger SP. Analysis of TP53 mutations in relapsed childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2001;23(7):416-419. (Pubitemid 33031768)
    • (2001) Journal of Pediatric Hematology/Oncology , vol.23 , Issue.7 , pp. 416-419
    • Gump, J.1    McGavran, L.2    Wei, Q.3    Hunger, S.P.4
  • 27
    • 53049109135 scopus 로고    scopus 로고
    • Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia
    • Case M, Matheson E, Minto L, et al. Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia. Cancer Res. 2008;68(16):6803-6809.
    • (2008) Cancer Res , vol.68 , Issue.16 , pp. 6803-6809
    • Case, M.1    Matheson, E.2    Minto, L.3
  • 28
    • 79251629946 scopus 로고    scopus 로고
    • The genetic landscape of the childhood cancer medulloblastoma
    • Parsons DW, Li M, Zhang X, et al. The genetic landscape of the childhood cancer medulloblastoma. Science. 2011;331(6016):435-439.
    • (2011) Science , vol.331 , Issue.6016 , pp. 435-439
    • Parsons, D.W.1    Li, M.2    Zhang, X.3
  • 29
    • 38849131230 scopus 로고    scopus 로고
    • TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis
    • DOI 10.1038/ncb1684, PII NCB1684
    • Li J, Wang CY. TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis. Nat Cell Biol. 2008;10(2):160-169. (Pubitemid 351194045)
    • (2008) Nature Cell Biology , vol.10 , Issue.2 , pp. 160-169
    • Li, J.1    Wang, C.-Y.2
  • 30
    • 79952430906 scopus 로고    scopus 로고
    • Inactivating mutations of acetyltransferase genes in B-cell lymphoma
    • Pasqualucci L, Dominguez-Sola D, Chiarenza A, et al. Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature. 2011;471(7337):189-195.
    • (2011) Nature , vol.471 , Issue.7337 , pp. 189-195
    • Pasqualucci, L.1    Dominguez-Sola, D.2    Chiarenza, A.3
  • 31
    • 33745713168 scopus 로고    scopus 로고
    • Activating alleles of JAK3 in acute megakaryoblastic leukemia
    • Walters DK, Mercher T, Gu TL, et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell. 2006;10(1):65-75.
    • (2006) Cancer Cell , vol.10 , Issue.1 , pp. 65-75
    • Walters, D.K.1    Mercher, T.2    Gu, T.L.3
  • 33
    • 9144244169 scopus 로고    scopus 로고
    • FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
    • DOI 10.1182/blood-2003-02-0418
    • Taketani T, Taki T, Sugita K, et al. FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rear-rangements and pediatric ALL with hyperdiploidy. Blood. 2004;103(3):1085-1088. (Pubitemid 38129575)
    • (2004) Blood , vol.103 , Issue.3 , pp. 1085-1088
    • Taketani, T.1    Taki, T.2    Sugita, K.3    Furuichi, Y.4    Ishii, E.5    Hanada, R.6    Tsuchida, M.7    Sugita, K.8    Ida, K.9    Hayashi, Y.10
  • 34
    • 35548934558 scopus 로고    scopus 로고
    • MLL translocations, histone modifications and leukaemia stem-cell development
    • DOI 10.1038/nrc2253, PII NRC2253
    • Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer. 2007;7(11):823-833. (Pubitemid 350006257)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.11 , pp. 823-833
    • Krivtsov, A.V.1    Armstrong, S.A.2
  • 35
    • 57149118627 scopus 로고    scopus 로고
    • Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia
    • DOI 10.1126/science.1164266
    • Mullighan CG, Phillips LA, Su X, et al. Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science. 2008;322 (5906):1377-1380. (Pubitemid 352775249)
    • (2008) Science , vol.322 , Issue.5906 , pp. 1377-1380
    • Mullighan, C.G.1    Phillips, L.A.2    Su, X.3    Ma, J.4    Miller, C.B.5    Shurtleff, S.A.6    Downing, J.R.7
  • 36
    • 78751661556 scopus 로고    scopus 로고
    • Evolution of human BCR-ABL1 lymphoblastic leukaemiainitiating cells
    • Notta F, Mullighan CG, Wang JC, et al. Evolution of human BCR-ABL1 lymphoblastic leukaemiainitiating cells. Nature. 2011;469(7330):362-367.
    • (2011) Nature , vol.469 , Issue.7330 , pp. 362-367
    • Notta, F.1    Mullighan, C.G.2    Wang, J.C.3
  • 37
    • 78751644099 scopus 로고    scopus 로고
    • Genetic variegation of clonal architecture and propagating cells in leukaemia
    • Anderson K, Lutz C, van Delft FW, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature. 2011;469(7330):356-361.
    • (2011) Nature , vol.469 , Issue.7330 , pp. 356-361
    • Anderson, K.1    Lutz, C.2    Van Delft, F.W.3
  • 38
    • 79955711142 scopus 로고    scopus 로고
    • Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse
    • Clappier E, Gerby B, Sigaux F, et al. Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse. J Exp Med. 2011;208(4):653-661.
    • (2011) J Exp Med , vol.208 , Issue.4 , pp. 653-661
    • Clappier, E.1    Gerby, B.2    Sigaux, F.3
  • 40
    • 32544448534 scopus 로고    scopus 로고
    • K-Ras mutations and N-Ras mutations in childhood acute leukemias with or without mixed-lineage leukemia gene rearrangements
    • Liang DC, Shih LY, Fu JF, et al. K-Ras mutations and N-Ras mutations in childhood acute leukemias with or without mixed-lineage leukemia gene rearrangements. Cancer. 2006;106(4):950-956.
    • (2006) Cancer , vol.106 , Issue.4 , pp. 950-956
    • Liang, D.C.1    Shih, L.Y.2    Fu, J.F.3
  • 44
    • 33747608619 scopus 로고    scopus 로고
    • Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: From thymocyte to lymphoblast
    • DOI 10.1038/sj.leu.2404302, PII 2404302
    • Graux C, Cools J, Michaux L, Vandenberghe P, Hagemeijer A. Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast. Leukemia. 2006;20(9):1496-1510. (Pubitemid 44264091)
    • (2006) Leukemia , vol.20 , Issue.9 , pp. 1496-1510
    • Graux, C.1    Cools, J.2    Michaux, L.3    Vandenberghe, P.4    Hagemeijer, A.5
  • 45
    • 70149087158 scopus 로고    scopus 로고
    • High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia
    • Gutierrez A, Sanda T, Grebliunaite R, et al. High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia. Blood. 2009;114(3):647-650.
    • (2009) Blood , vol.114 , Issue.3 , pp. 647-650
    • Gutierrez, A.1    Sanda, T.2    Grebliunaite, R.3
  • 46
    • 21344448655 scopus 로고    scopus 로고
    • Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia
    • DOI 10.1038/sj.onc.1208588
    • Barjesteh van Waalwijk van Doorn-Khosrovani S, Spensberger D, de Knegt Y, Tang M, Lowenberg B, Delwel R. Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia. Oncogene. 2005;24(25):4129-4137. (Pubitemid 40903096)
    • (2005) Oncogene , vol.24 , Issue.25 , pp. 4129-4137
    • Barjesteh Van Waalwijk Van Doorn-Khosrovani, S.1    Spensberger, D.2    De Knegt, Y.3    Tang, M.4    Lowenberg, B.5    Delwel, R.6
  • 47
    • 57149113918 scopus 로고    scopus 로고
    • The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1
    • Parker H, An Q, Barber K, et al. The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1. Genes Chromosomes Cancer. 2008;47(12):1118-1125.
    • (2008) Genes Chromosomes Cancer , vol.47 , Issue.12 , pp. 1118-1125
    • Parker, H.1    An, Q.2    Barber, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.